1,2,3,4-Tetrachloro-3-Nitrobenzene
Linshang Chemical
HS Code |
970410 |
Chemical Formula | C6HCl4NO2 |
Molecular Weight | 266.89 g/mol |
Appearance | Yellow - crystalline solid |
Odor | Typical of chlorinated and nitro - aromatic compounds |
Melting Point | 78 - 80 °C |
Boiling Point | 312 - 314 °C |
Density | 1.74 g/cm³ (approximate) |
Solubility In Water | Very low, sparingly soluble |
Solubility In Organic Solvents | Soluble in many organic solvents like benzene, toluene |
Vapor Pressure | Low vapor pressure at room temperature |
As an accredited 1,2,3,4-Tetrachloro-3-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500g of 1,2,3,4 - tetrachloro - 3 - nitrobenzene packaged in air - tight plastic bags. |
Storage | 1,2,3,4 - Tetrachloro - 3 - nitrobenzene is a hazardous chemical. Store it in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Separate it from oxidizing agents, reducing agents, and combustibles to prevent potential reactions. |
Shipping | 1,2,3,4 - Tetrachloro - 3 - nitrobenzene, a hazardous chemical, is shipped in specialized, tightly - sealed containers. These containers are compliant with international regulations to prevent leakage during transit. |
Competitive 1,2,3,4-Tetrachloro-3-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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As a leading 1,2,3,4-Tetrachloro-3-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
This substance is stable in nature and does not easily react chemically under normal conditions. Its vapor is heavier than air and can be diffused at a lower place to a considerable distance. Carbon tetrachloride was widely used as a fire extinguishing agent because it is non-flammable and steam can isolate air. However, it is rarely used today because of its destructive effect on the ozone layer.
In industry, carbon tetrachloride has also been used as a solvent to dissolve oils, resins, rubber and other substances. Due to its good solubility, it can assist in the progress of many chemical reactions and the separation and purification of substances. However, due to its toxicity and environmental hazards, other more environmentally friendly and safe solvents are now replaced. The chloroform referred to in
3 is also a colorless, transparent and volatile liquid with a special sweet smell. Its density is also greater than that of water, insoluble in water, and miscible with most organic solvents. Chloroform is relatively stable chemically, but under the action of light and oxygen in the air, it will gradually decompose to produce highly toxic phosgene. Therefore, chloroform is usually stored in a brown bottle with an appropriate amount of ethanol as a stabilizer.
Chloroform was often used as an anesthetic in the medical field in the early days. However, due to its damage to the human nervous system and liver and other organs, it is now less used for this purpose. In industry, chloroform is mainly used in the production of chemical products such as Freon, or as an intermediate in organic synthesis.
As for benzyl chloride, it is a colorless and transparent liquid with a strong pungent odor. Its density is greater than that of water, it is insoluble in water, and it can be miscible in most organic solvents such as ethanol and chloroform. Benzyl chloride is chemically active. Due to the presence of chlorine atoms in its molecules, it is prone to nucleophilic substitution reactions. It can be used to prepare a variety of organic compounds, such as fragrances, drugs, dyes However, benzyl chloride is corrosive and toxic, and has a strong irritating effect on the eyes, skin, and respiratory tract. Therefore, extra caution and protective measures should be taken when using it.
- ** Nucleophilic substitution reaction **: Because the halogen atom can be used as a leaving group, under the action of the nucleophilic reagent, the halogen atom will be replaced by the nucleophilic reagent. If under basic conditions, the hydroxyl group ($OH ^ - $) can replace the halogen atom as a nucleophilic reagent to form the corresponding phenolic compound. During the reaction, the nucleophilic reagent attacks the benzene ring and connects the carbon atom to the halogen atom, and
- ** Electrophilic Substitution Reaction **: The benzene ring is electron-rich and susceptible to attack by electrophilic reagents. The halogen atom is an ortho-and para-site locator, which will increase the electron cloud density of the benzene ring ortho-and para-site relatively, and the electrophilic reagents are easy to attack ortho-and para-sites. For example, during nitrification, the nitro group ($NO_2 ^ + $) acts as an electrophilic reagent and is mainly substituted in the ortho-and para-sites of the halogen atom to generate the corresponding nitro compound.
- ** Reduction Reaction **: The halogen atom in the molecule can be reduced and removed under the action of a suitable reducing agent. If a metal zinc and an acid are used to form a system, the halogen atom can In this reaction, metal zinc provides electrons, so that the halogen atom gets electrons to form a halogen ion and leaves.
- ** Metal Organic Reaction **: This compound can react with metal reagents to form metal organic compounds. For example, it reacts with magnesium to form Grignard reagents, which are extremely important in organic synthesis and can be used to build carbon-carbon bonds. It reacts with electrophilic reagents such as carbonyl compounds to generate various organic compounds, greatly expanding its application in the field of organic synthesis.
In the field of medicine, this group plays a key role in the design and synthesis of many drug molecules. Because of its specific chemical structure and properties, it can interact with specific targets in organisms, or exhibit antibacterial effects, inhibit bacterial growth and reproduction, and protect the human body from pathogens; or have anti-tumor activity, inhibit the growth and spread of tumor cells, and bring new opportunities for cancer treatment. For example, some new anti-cancer drugs have skillfully introduced this group and precisely acted on key proteins or signaling pathways of cancer cells to achieve high-efficiency anti-cancer purposes.
In the field of organic synthesis, mono-, di-, tri-, and tetrahydro-3-quinolinyl groups are like an important synthetic building block. With their unique structure, more complex and novel organic compounds can be constructed by means of diverse chemical reactions. Organic chemists often use it to build molecular frameworks with special spatial configurations and functions, injecting new vitality into the development of organic synthetic chemistry, and promoting cutting-edge research fields such as new materials and functional molecules.
In the field of materials science, compounds containing this group can be specially treated and processed to prepare materials with unique optical, electrical or mechanical properties. For example, it is possible to prepare optical materials with excellent absorption or emission properties for specific wavelengths of light, which can be used in optoelectronic devices such as Light Emitting Diodes, laser materials, etc.; or to prepare materials with special electrical conductivity properties, which can contribute to the development of miniaturization and high performance of electronic devices.
These chemicals have a very important impact on the environment. In the theory of carbon tetrachloride, it was widely used in dry cleaning, fire extinguishing agents and other fields in the past because of its good solubility. However, with in-depth research, it was found that it has a serious destructive effect on the ozone layer. Carbon tetrachloride decomposes chlorine atoms under ultraviolet irradiation. This chlorine atom can catalyze the decomposition of ozone, cause the ozone layer to thin, weaken its ability to shield against ultraviolet rays, and threaten the survival of earth organisms.
As for "3-chlorobenzene", if it enters the environment, it degrades slowly in the natural environment due to the stability of the benzene ring. It may migrate through soil, water and other pathways, affecting the surrounding ecosystem. If an organism ingests environmental media containing this substance, or accumulates in the organism, it will affect the normal physiological functions of the organism, such as interfering with the activity of enzymes in the organism, affecting cell metabolism, etc., and then causing a chain reaction on the ecological chain. Overall, the presence of such chemicals in the environment poses a potential threat to ecological balance and requires careful treatment and reasonable control.
First take an appropriate reaction vessel, wash and dry it to ensure that there are no water stains and impurities to avoid disturbance to the reaction. Prepare the raw materials and reagents required for the synthesis of 1,2,3,4-tetrahydro-3-carboxylindole, such as specific starting reactants, catalysts, solvents, etc., and ensure high purity to avoid impurities from accumulating in the product.
Pour the measured starting reactants into the reaction vessel in a specific order and proportion. This process needs to be handled carefully and used strictly according to the amount, because the proportion of raw materials has a great influence on the reaction process and product purity. Subsequently, add an appropriate amount of catalyst. The catalyst can change the rate of chemical reaction, which is a key factor in this reaction. The precise dosage can make the reaction proceed efficiently.
Then, a suitable solvent is slowly added to fully disperse and mix the reactants evenly, which is conducive to the full development of the reaction. After that, the reaction vessel is placed in a specific environment and adjusted to the required temperature and pressure conditions. The control of temperature and pressure is of paramount importance, and its fluctuations can make the reaction direction, rate and product distribution different.
During the reaction, it is necessary to closely observe the process. By means of various analytical methods, such as thin-layer chromatography, high-performance liquid chromatography, etc., the consumption of reactants and the production of products can be regularly monitored. According to the monitoring results, the reaction conditions can be fine-tuned in a timely manner to ensure that the reaction proceeds along the expected path.
After the reaction is completed, the product is separated and purified. First, suitable separation methods, such as filtration, extraction, distillation, etc., are used to separate the product from the reaction system. After purification methods such as column chromatography and recrystallization, high purity 1,2,3,4-tetrahydro-3-carboxyindole is obtained by removing impurities. The whole preparation process requires fine operation and strict compliance with procedures to obtain good quality products.

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