Linshang Chemical
PRODUCTS
1,2,3-Trichloro-5-Nitrobenzene
Linshang Chemical
|
HS Code |
854244 |
| Chemical Formula | C6H2Cl3NO2 |
| Molar Mass | 238.44 g/mol |
| Appearance | Yellow solid |
| Odor | Pungent |
| Density | 1.74 g/cm³ |
| Melting Point | 57 - 60 °C |
| Boiling Point | 276 - 277 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in benzene, toluene, etc. |
| Vapor Pressure | Low |
As an accredited 1,2,3-Trichloro-5-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 kg of 1,2,3 - trichloro - 5 - nitrobenzene packaged in a sealed, labeled drum. |
| Storage | 1,2,3 - Trichloro - 5 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly - sealed container to prevent leakage. Store it separately from oxidizing agents, reducing agents, and incompatible substances to avoid reactions. Adhere to safety regulations for handling and storing hazardous chemicals. |
| Shipping | 1,2,3 - trichloro - 5 - nitrobenzene is a hazardous chemical. It must be shipped in accordance with strict regulations, using appropriate containers to prevent leakage, and accompanied by proper safety documentation. |
Competitive 1,2,3-Trichloro-5-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1,2,3-Trichloro-5-Nitrobenzene in China?
As a trusted 1,2,3-Trichloro-5-Nitrobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1,2,3-Trichloro-5-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 1,2,3-trichloro-5-nitrobenzene?
1% 2C2% 2C3 refers to the substance, that is, trichloromethane, also known as chloroform, which is a colorless, transparent and volatile liquid with a special sweet smell. Its physical properties are as follows:
- ** Appearance and odor **: It is colorless and transparent under normal circumstances, and has a special sweet smell when smelled. However, this smell is not a pleasant fragrance. Instead, it is toxic and harmful to the human body if inhaled too much.
- ** Volatile **: It is highly volatile. In a room temperature environment, trichloromethane liquid can quickly transform into a gaseous state and dissipate into the air. This characteristic requires special attention when using and storing it to prevent the concentration of volatilization from being too high and causing danger.
- ** Density **: The density is greater than that of water. When trichloromethane is mixed with water, it will sink to the bottom of the water. This property can be exploited in some separation and extraction operations.
- ** Solubility **: Slightly soluble in water, but can be miscible with many organic solvents such as ethanol and ether in any ratio. This solubility makes trichloromethane a common solvent in the field of organic synthesis and chemical analysis.
- ** Boiling point and melting point **: The boiling point is relatively low, about 61.2 ° C, and it is easy to boil into a gaseous state when heated slightly; the melting point is -63.5 ° C, and it can still maintain a liquid state at lower temperatures. The phenol referred to in
5, commonly known as carbolic acid, is a colorless needle-like crystal with a special odor. Its physical properties are as follows:
- ** Appearance **: It is a colorless needle-like crystal under normal circumstances, but it often appears pink because it is easily oxidized.
- ** Odor **: It has a special smell. This smell is quite unique, easy to identify, and because of its toxicity, it is harmful to the human body.
- ** Melting point **: The melting point is 43 ° C, and the temperature is slightly higher than this. Phenol melts from solid to liquid. This property needs to be taken into account when storing and using it.
- ** Solubility **: At room temperature, the solubility in water is limited, and when the temperature increases, the solubility will increase; in addition, phenol is easily soluble in organic solvents such as ethanol and ether, which makes it widely used in organic synthesis and other fields.
- ** Volatility **: It is volatile to a certain extent, although it is not as volatile as trichloromethane, it will also evaporate slowly in the air, so it needs to be sealed and stored to prevent volatilization loss and pollution of the environment.
- ** Appearance and odor **: It is colorless and transparent under normal circumstances, and has a special sweet smell when smelled. However, this smell is not a pleasant fragrance. Instead, it is toxic and harmful to the human body if inhaled too much.
- ** Volatile **: It is highly volatile. In a room temperature environment, trichloromethane liquid can quickly transform into a gaseous state and dissipate into the air. This characteristic requires special attention when using and storing it to prevent the concentration of volatilization from being too high and causing danger.
- ** Density **: The density is greater than that of water. When trichloromethane is mixed with water, it will sink to the bottom of the water. This property can be exploited in some separation and extraction operations.
- ** Solubility **: Slightly soluble in water, but can be miscible with many organic solvents such as ethanol and ether in any ratio. This solubility makes trichloromethane a common solvent in the field of organic synthesis and chemical analysis.
- ** Boiling point and melting point **: The boiling point is relatively low, about 61.2 ° C, and it is easy to boil into a gaseous state when heated slightly; the melting point is -63.5 ° C, and it can still maintain a liquid state at lower temperatures. The phenol referred to in
5, commonly known as carbolic acid, is a colorless needle-like crystal with a special odor. Its physical properties are as follows:
- ** Appearance **: It is a colorless needle-like crystal under normal circumstances, but it often appears pink because it is easily oxidized.
- ** Odor **: It has a special smell. This smell is quite unique, easy to identify, and because of its toxicity, it is harmful to the human body.
- ** Melting point **: The melting point is 43 ° C, and the temperature is slightly higher than this. Phenol melts from solid to liquid. This property needs to be taken into account when storing and using it.
- ** Solubility **: At room temperature, the solubility in water is limited, and when the temperature increases, the solubility will increase; in addition, phenol is easily soluble in organic solvents such as ethanol and ether, which makes it widely used in organic synthesis and other fields.
- ** Volatility **: It is volatile to a certain extent, although it is not as volatile as trichloromethane, it will also evaporate slowly in the air, so it needs to be sealed and stored to prevent volatilization loss and pollution of the environment.
What are the chemical properties of 1,2,3-trichloro-5-nitrobenzene?
1% 2C2% 2C3 shall refer to monofluorodichlorotribromomethane, which is commonly known as Freon-113. It is a colorless and transparent volatile liquid with a slight ether taste at room temperature and pressure.
Monofluorodichlorotribromomethane has the following chemical properties:
1. ** Stability **: It is relatively stable at room temperature, but may decompose at high temperatures, open flames or in contact with certain active substances. Its decomposition products may contain toxic and corrosive hydrogen halide gas. For example, in a fire scene, it will decompose to produce hydrogen chloride, hydrogen bromide and other gases. These gases not only have strong irritation to the human respiratory tract, but also have a corrosive effect on substances such as metals in the surrounding environment.
2. ** Reactivity **: As a halogenated hydrocarbon, it can participate in a variety of organic reactions. For example, nucleophilic substitution reaction, the halogen atoms in the molecule can be replaced by other nucleophilic reagents. Take the reaction with sodium hydroxide aqueous solution as an example, under appropriate conditions, the halogen atoms will be gradually replaced by hydroxyl groups to generate corresponding alcohols.
3. ** Solubility **: It is slightly soluble in water, but it can be miscible with many organic solvents, such as common ether, acetone, etc. This solubility characteristic makes it often used as a solvent in industry to dissolve some organic compounds that are not soluble in water. However, due to its destructive effect on the ozone layer, its current use has been strictly limited.
5-cyanopyridine, from a structural point of view, is a compound in which the 5th position of the pyridine ring is replaced by a cyanyl group (-CN). Its chemical properties are as follows:
1. ** Nucleophilic reaction **: The cyanyl group has a strong electron-withdrawing property, which changes the electron cloud density on the pyridine ring. This results in the pyridine ring being more susceptible to attack by nucleophilic testers. For example, under alkaline conditions, nucleophilic addition reactions can occur with water, and the cyanyl group is gradually hydrolyzed to carboxyl groups to generate 5-pyridinecarboxylic acid.
2. ** Basic **: The lone pair of electrons on the nitrogen atom of the pyridine ring makes it alkaline and can react with acids to form salts. For example, by reacting with hydrochloric acid, a corresponding hydrochloride salt can be formed, and the solubility of this salt in water is usually better than that of 5-cyanopyridine itself.
3. ** Redox Reaction **: The cyano group can be reduced. Under the action of a suitable reducing agent such as lithium aluminum hydride, the cyano group can be reduced to an amino group to obtain 5-aminomethylpyridine. At the same time, the pyridine ring can also be oxidized under the action of a specific oxidant, but the reaction conditions are more harsh and the product is more complex.
Monofluorodichlorotribromomethane has the following chemical properties:
1. ** Stability **: It is relatively stable at room temperature, but may decompose at high temperatures, open flames or in contact with certain active substances. Its decomposition products may contain toxic and corrosive hydrogen halide gas. For example, in a fire scene, it will decompose to produce hydrogen chloride, hydrogen bromide and other gases. These gases not only have strong irritation to the human respiratory tract, but also have a corrosive effect on substances such as metals in the surrounding environment.
2. ** Reactivity **: As a halogenated hydrocarbon, it can participate in a variety of organic reactions. For example, nucleophilic substitution reaction, the halogen atoms in the molecule can be replaced by other nucleophilic reagents. Take the reaction with sodium hydroxide aqueous solution as an example, under appropriate conditions, the halogen atoms will be gradually replaced by hydroxyl groups to generate corresponding alcohols.
3. ** Solubility **: It is slightly soluble in water, but it can be miscible with many organic solvents, such as common ether, acetone, etc. This solubility characteristic makes it often used as a solvent in industry to dissolve some organic compounds that are not soluble in water. However, due to its destructive effect on the ozone layer, its current use has been strictly limited.
5-cyanopyridine, from a structural point of view, is a compound in which the 5th position of the pyridine ring is replaced by a cyanyl group (-CN). Its chemical properties are as follows:
1. ** Nucleophilic reaction **: The cyanyl group has a strong electron-withdrawing property, which changes the electron cloud density on the pyridine ring. This results in the pyridine ring being more susceptible to attack by nucleophilic testers. For example, under alkaline conditions, nucleophilic addition reactions can occur with water, and the cyanyl group is gradually hydrolyzed to carboxyl groups to generate 5-pyridinecarboxylic acid.
2. ** Basic **: The lone pair of electrons on the nitrogen atom of the pyridine ring makes it alkaline and can react with acids to form salts. For example, by reacting with hydrochloric acid, a corresponding hydrochloride salt can be formed, and the solubility of this salt in water is usually better than that of 5-cyanopyridine itself.
3. ** Redox Reaction **: The cyano group can be reduced. Under the action of a suitable reducing agent such as lithium aluminum hydride, the cyano group can be reduced to an amino group to obtain 5-aminomethylpyridine. At the same time, the pyridine ring can also be oxidized under the action of a specific oxidant, but the reaction conditions are more harsh and the product is more complex.
In what fields is 1,2,3-trichloro-5-nitrobenzene used?
1% 2C2% 2C3 is triA, which is a term in traditional Chinese medicine, and often refers to three different grades of medicinal materials. And "tribromine" is not a common Chinese medicine expression, and it is suspected to be a clerical error. 5-Cyanopyridine, which is an important raw material for organic synthesis, is also used in the field of medicine.
In the field of traditional Chinese medicine, triA is mainly used in orthopedics and traumatology, tonifying deficiency, etc. In ancient times, doctors often used triA in combination with other medicinal materials to treat bruises and injuries, to help build bones and tendons, promote blood circulation and remove blood stasis. In case of weakness syndrome of muscle and bone weakness, triA is also used as medicine to nourish liver and kidney, strengthen tendons and bones.
Although 5-cyanopyridine is not a traditional Chinese medicine ingredient, its role in modern medicine research cannot be underestimated. Many studies have been devoted to using 5-cyanopyridine as a starting material to synthesize new drug molecules for the treatment of various diseases, such as certain cardiovascular diseases and nervous system diseases. Due to the special chemical structure of 5-cyanopyridine, it can be converted into bioactive compounds through specific chemical reactions, thus exerting therapeutic effects.
In summary, trimethyl has long been used in the field of traditional Chinese medicine, while 5-cyanopyridine has broad prospects in the field of modern medicine research and development. Although the sources and application methods are different, both have made great contributions to human health.
In the field of traditional Chinese medicine, triA is mainly used in orthopedics and traumatology, tonifying deficiency, etc. In ancient times, doctors often used triA in combination with other medicinal materials to treat bruises and injuries, to help build bones and tendons, promote blood circulation and remove blood stasis. In case of weakness syndrome of muscle and bone weakness, triA is also used as medicine to nourish liver and kidney, strengthen tendons and bones.
Although 5-cyanopyridine is not a traditional Chinese medicine ingredient, its role in modern medicine research cannot be underestimated. Many studies have been devoted to using 5-cyanopyridine as a starting material to synthesize new drug molecules for the treatment of various diseases, such as certain cardiovascular diseases and nervous system diseases. Due to the special chemical structure of 5-cyanopyridine, it can be converted into bioactive compounds through specific chemical reactions, thus exerting therapeutic effects.
In summary, trimethyl has long been used in the field of traditional Chinese medicine, while 5-cyanopyridine has broad prospects in the field of modern medicine research and development. Although the sources and application methods are different, both have made great contributions to human health.
What is the preparation method of 1,2,3-trichloro-5-nitrobenzene?
To prepare the preparation of tribromo-5-cyanopyridine, the method is as follows:
First, take an appropriate reaction vessel, clean and dry to ensure that the reaction environment is suitable. Prepare the raw materials completely, and the purity of the materials used must be up to standard, which is the basis for the successful reaction.
In the container, according to a certain ratio, put in the relevant reagents. First put in the pyridine compound, which is the core substrate of the reaction, and the dosage is accurately weighed to determine the benchmark of the reaction. Then slowly add the brominating reagent. This process should be slow and uniform. At the same time, pay close attention to the temperature change of the reaction system. Because the bromination reaction is often exothermic, if the temperature is out of control, it is easy to cause side reactions. Control the reaction temperature in a moderate range, which can be adjusted by methods such as cooling device or water bath heating, so that the reaction can proceed smoothly.
After the bromination reaction is completed, a cyanylating agent is introduced. The cyanylation step also needs to be handled with caution, because it involves highly toxic reagents, and safety procedures must be strictly observed. Regulate the reaction conditions, such as pH, reaction time, etc. PH has a great influence on the rate and selectivity of the cyanylation reaction, so it needs to be fine-tuned with acid-base regulators. The control of the reaction time is also related to the purity and yield of the product. The reaction process needs to be monitored by experimental means, such as thin-layer chromatography, to stop the reaction in a timely manner.
After the reaction is completed, the product needs to be separated and purified. First extract with a suitable solvent to preliminarily separate the product from the impurities. The choice of extraction solvent depends on the difference in solubility between the product and the impurities. Then it is further purified by column chromatography or recrystallization. During column chromatography, appropriate stationary phase and eluent are selected to separate the product and impurities according to adsorption and desorption. Recrystallization controls the temperature and solvent dosage to crystallize the product and precipitate it to obtain high-purity tribromo-5-cyanopyridine. The whole preparation process requires rigorous operation at each step to obtain a high-quality product.
First, take an appropriate reaction vessel, clean and dry to ensure that the reaction environment is suitable. Prepare the raw materials completely, and the purity of the materials used must be up to standard, which is the basis for the successful reaction.
In the container, according to a certain ratio, put in the relevant reagents. First put in the pyridine compound, which is the core substrate of the reaction, and the dosage is accurately weighed to determine the benchmark of the reaction. Then slowly add the brominating reagent. This process should be slow and uniform. At the same time, pay close attention to the temperature change of the reaction system. Because the bromination reaction is often exothermic, if the temperature is out of control, it is easy to cause side reactions. Control the reaction temperature in a moderate range, which can be adjusted by methods such as cooling device or water bath heating, so that the reaction can proceed smoothly.
After the bromination reaction is completed, a cyanylating agent is introduced. The cyanylation step also needs to be handled with caution, because it involves highly toxic reagents, and safety procedures must be strictly observed. Regulate the reaction conditions, such as pH, reaction time, etc. PH has a great influence on the rate and selectivity of the cyanylation reaction, so it needs to be fine-tuned with acid-base regulators. The control of the reaction time is also related to the purity and yield of the product. The reaction process needs to be monitored by experimental means, such as thin-layer chromatography, to stop the reaction in a timely manner.
After the reaction is completed, the product needs to be separated and purified. First extract with a suitable solvent to preliminarily separate the product from the impurities. The choice of extraction solvent depends on the difference in solubility between the product and the impurities. Then it is further purified by column chromatography or recrystallization. During column chromatography, appropriate stationary phase and eluent are selected to separate the product and impurities according to adsorption and desorption. Recrystallization controls the temperature and solvent dosage to crystallize the product and precipitate it to obtain high-purity tribromo-5-cyanopyridine. The whole preparation process requires rigorous operation at each step to obtain a high-quality product.
What are the effects of 1,2,3-trichloro-5-nitrobenzene on the environment and humans?
1% 2C2% 2C3, although these three are common in the world, compared with pentacyanopyridine, they each have their own unique effects on the environment and human body.
First of all, tribromine, tribromine, in the environment, or can be dispersed in various ways. If it exists in water bodies, or causes water quality variation, it affects the habitat of aquatic organisms, and hinders the reproduction and survival of many aquatic organisms. For the human body, if it is inadvertently touched or penetrated through the skin, it can cause skin diseases such as redness, swelling, itching and even ulceration. If ingested through breathing, it may damage the respiratory tract, cause cough, asthma, long-term exposure, or affect lung function, endangering life and health.
Fifth, in the environment, it may change the nature of the soil, affect the absorption of nutrients by plants, and then affect the growth of vegetation, resulting in ecological imbalance. If it enters the human body, it may interfere with the normal metabolism of the human body, involve the function of the viscera, and affect the normal operation of the body.
As for cyanopyridine, it is quite harmful to the environment. In the soil, it may inhibit the activity of microorganisms and destroy the balance of the soil ecosystem. In water bodies, it can cause water pollution and affect the survival of aquatic animals and plants. To the human body, cyanopyridine is toxic. If ingested or inhaled by mistake, it can quickly endanger life. It may interfere with the nervous system of the human body, causing dizziness, convulsions, and even coma and death.
In short, these substances pose potential hazards to the environment and the human body. The world should treat them with caution and strengthen prevention to ensure the safety of the environment and personal health.
First of all, tribromine, tribromine, in the environment, or can be dispersed in various ways. If it exists in water bodies, or causes water quality variation, it affects the habitat of aquatic organisms, and hinders the reproduction and survival of many aquatic organisms. For the human body, if it is inadvertently touched or penetrated through the skin, it can cause skin diseases such as redness, swelling, itching and even ulceration. If ingested through breathing, it may damage the respiratory tract, cause cough, asthma, long-term exposure, or affect lung function, endangering life and health.
Fifth, in the environment, it may change the nature of the soil, affect the absorption of nutrients by plants, and then affect the growth of vegetation, resulting in ecological imbalance. If it enters the human body, it may interfere with the normal metabolism of the human body, involve the function of the viscera, and affect the normal operation of the body.
As for cyanopyridine, it is quite harmful to the environment. In the soil, it may inhibit the activity of microorganisms and destroy the balance of the soil ecosystem. In water bodies, it can cause water pollution and affect the survival of aquatic animals and plants. To the human body, cyanopyridine is toxic. If ingested or inhaled by mistake, it can quickly endanger life. It may interfere with the nervous system of the human body, causing dizziness, convulsions, and even coma and death.
In short, these substances pose potential hazards to the environment and the human body. The world should treat them with caution and strengthen prevention to ensure the safety of the environment and personal health.
Scan to WhatsApp
