Linshang Chemical
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1,2,3-Trichloro-5-(Trifluoromethyl)-Benzene
Linshang Chemical
|
HS Code |
538336 |
| Chemical Formula | C7H2Cl3F3 |
| Molar Mass | 247.44 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 185 - 187 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like benzene, toluene |
As an accredited 1,2,3-Trichloro-5-(Trifluoromethyl)-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram bottles for 1,2,3 - trichloro - 5-(trifluoromethyl) - benzene, well - sealed. |
| Storage | 1,2,3 - trichloro - 5 - (trifluoromethyl) - benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials like stainless steel or certain plastics, to prevent leakage and exposure to air and moisture. |
| Shipping | 1,2,3 - trichloro - 5 - (trifluoromethyl) - benzene is shipped in tightly sealed, corrosion - resistant containers. Transport follows strict chemical safety regulations, ensuring proper handling to prevent spills and exposure during transit. |
Competitive 1,2,3-Trichloro-5-(Trifluoromethyl)-Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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What are the physical properties of 1,2,3-trichloro-5- (trifluoromethyl) benzene?
1% 2C2% 2C3-tribromo-5- (tribromo-methyl) benzene is an organic compound. Its physical properties are as follows:
In terms of appearance, this compound is often white to light yellow crystalline powder. It has a special smell, but its smell is not very strong and pungent.
Its melting point is quite high, about 150 ° C - 160 ° C. This property is due to the strong interaction force between molecules, which requires a higher temperature to disintegrate its lattice structure and convert from solid to liquid.
As for solubility, it shows good solubility in common organic solvents such as dichloromethane and chloroform. Due to the similarity between the molecular structures of these organic solvents and the molecular structures of 1% 2C2% 2C3-tribromo-5- (tribromo-methyl) benzene, they are easy to mix with each other according to the principle of "similar miscibility". However, their solubility in water is extremely poor and almost insoluble. Because this compound is a non-polar organic molecule and water is a polar molecule, the forces between the two molecules are very different and it is difficult to dissolve each other.
Furthermore, its density is higher than that of water. If it is mixed with water, it will sink to the bottom of the water. Because the molecules of this compound are relatively large in weight and the molecules are tightly packed, the mass per unit volume is higher than that of water.
In terms of appearance, this compound is often white to light yellow crystalline powder. It has a special smell, but its smell is not very strong and pungent.
Its melting point is quite high, about 150 ° C - 160 ° C. This property is due to the strong interaction force between molecules, which requires a higher temperature to disintegrate its lattice structure and convert from solid to liquid.
As for solubility, it shows good solubility in common organic solvents such as dichloromethane and chloroform. Due to the similarity between the molecular structures of these organic solvents and the molecular structures of 1% 2C2% 2C3-tribromo-5- (tribromo-methyl) benzene, they are easy to mix with each other according to the principle of "similar miscibility". However, their solubility in water is extremely poor and almost insoluble. Because this compound is a non-polar organic molecule and water is a polar molecule, the forces between the two molecules are very different and it is difficult to dissolve each other.
Furthermore, its density is higher than that of water. If it is mixed with water, it will sink to the bottom of the water. Because the molecules of this compound are relatively large in weight and the molecules are tightly packed, the mass per unit volume is higher than that of water.
What are the chemical properties of 1,2,3-trichloro-5- (trifluoromethyl) benzene?
1% 2C2% 2C3 -tribromo-5- (tribromo-methyl) benzene, this is an organic compound. Its chemical properties are as follows:
- ** Stability **: Under normal circumstances, the compound has a certain chemical stability. However, due to the fact that its molecule contains multiple bromine atoms, these bromine atoms are relatively active, and when encountered with specific reagents or reaction conditions, the stability of the entire molecule will be affected. For example, in the presence of strong reducing agents, bromine atoms may be reduced, resulting in changes in molecular structure.
- ** Substitution Reaction Characteristics **: Bromine atoms in the molecule can be used as good leaving groups. When it encounters a nucleophilic reagent, it is prone to nucleophilic substitution reactions. For example, if a nucleophilic reagent such as a hydroxyl negative ion attacks, the bromine atom may be replaced by a hydroxyl group, and then a new hydroxyl-containing compound is formed. This is due to the electronegativity of the bromine atom and its atomic radius and other factors, which make the C-Br bond relatively easy to break, creating conditions for the attack of the nucleophilic reagent.
- ** Addition Reaction Situation **: Although there are no common functional groups prone to addition reactions such as typical carbon-carbon double bonds in the molecule of this compound, under specific catalytic conditions, such as the action of some transition metal catalysts, the carbon atom where the bromine atom is located may undergo an addition reaction with some unsaturated reagents, thereby enriching the structure and properties of the molecule.
- ** Solubility characteristics **: Due to the fact that it contains multiple bromine atoms, the relative molecular weight is large, and the bromine atoms have certain hydrophobicity, the solubility of this compound in water is low. However, in some organic solvents, such as halogenated hydrocarbon solvents such as dichloromethane and chloroform, it may have good solubility, which is related to the principle of "similar compatibility", that is, substances with similar structures and polarities are more likely to dissolve with each other.
- ** Stability **: Under normal circumstances, the compound has a certain chemical stability. However, due to the fact that its molecule contains multiple bromine atoms, these bromine atoms are relatively active, and when encountered with specific reagents or reaction conditions, the stability of the entire molecule will be affected. For example, in the presence of strong reducing agents, bromine atoms may be reduced, resulting in changes in molecular structure.
- ** Substitution Reaction Characteristics **: Bromine atoms in the molecule can be used as good leaving groups. When it encounters a nucleophilic reagent, it is prone to nucleophilic substitution reactions. For example, if a nucleophilic reagent such as a hydroxyl negative ion attacks, the bromine atom may be replaced by a hydroxyl group, and then a new hydroxyl-containing compound is formed. This is due to the electronegativity of the bromine atom and its atomic radius and other factors, which make the C-Br bond relatively easy to break, creating conditions for the attack of the nucleophilic reagent.
- ** Addition Reaction Situation **: Although there are no common functional groups prone to addition reactions such as typical carbon-carbon double bonds in the molecule of this compound, under specific catalytic conditions, such as the action of some transition metal catalysts, the carbon atom where the bromine atom is located may undergo an addition reaction with some unsaturated reagents, thereby enriching the structure and properties of the molecule.
- ** Solubility characteristics **: Due to the fact that it contains multiple bromine atoms, the relative molecular weight is large, and the bromine atoms have certain hydrophobicity, the solubility of this compound in water is low. However, in some organic solvents, such as halogenated hydrocarbon solvents such as dichloromethane and chloroform, it may have good solubility, which is related to the principle of "similar compatibility", that is, substances with similar structures and polarities are more likely to dissolve with each other.
What are the main uses of 1,2,3-trichloro-5- (trifluoromethyl) benzene?
1% 2C2% 2C3-tribromo-5- (tribromomethyl) benzene, this substance has important uses in many fields.
In the field of pharmaceutical synthesis, it is often a key intermediate. Due to the structural characteristics of the phenyl ring and bromine atoms and methyl groups, it can react with various functional groups by organic synthesis methods, and through series transformation, construct a complex drug molecular structure. For example, when synthesizing specific anti-cancer drugs, it can precisely connect with other active groups according to their structures to form molecules with specific pharmacological activities, contributing to the research and development of anti-cancer drugs.
In the field of materials science, due to the bromine element, it has good flame retardant properties. Incorporating it into polymer materials, such as plastics and fibers, when exposed to fire, bromine atoms can inhibit combustion reactions, reduce material flammability, and improve the fire safety level of materials by means of mechanisms such as gas phase flame retardancy and condensed phase flame retardancy. It is widely used in construction, electronics and other fields that require strict material flame retardancy.
In organic synthetic chemistry, it is also an important raw material. With its special functional groups, it can participate in nucleophilic substitution, electrophilic substitution and other reactions, providing the possibility for the synthesis of novel organic compounds, assisting chemists in exploring the structure and properties of new substances, and promoting the continuous progress of organic chemistry theory and practice.
In conclusion, 1% 2C2% 2C3-tribromo-5- (tribromo-methyl) benzene plays a significant role in the fields of medicine, materials, and organic synthesis, and has a profound impact on the development of related industries.
In the field of pharmaceutical synthesis, it is often a key intermediate. Due to the structural characteristics of the phenyl ring and bromine atoms and methyl groups, it can react with various functional groups by organic synthesis methods, and through series transformation, construct a complex drug molecular structure. For example, when synthesizing specific anti-cancer drugs, it can precisely connect with other active groups according to their structures to form molecules with specific pharmacological activities, contributing to the research and development of anti-cancer drugs.
In the field of materials science, due to the bromine element, it has good flame retardant properties. Incorporating it into polymer materials, such as plastics and fibers, when exposed to fire, bromine atoms can inhibit combustion reactions, reduce material flammability, and improve the fire safety level of materials by means of mechanisms such as gas phase flame retardancy and condensed phase flame retardancy. It is widely used in construction, electronics and other fields that require strict material flame retardancy.
In organic synthetic chemistry, it is also an important raw material. With its special functional groups, it can participate in nucleophilic substitution, electrophilic substitution and other reactions, providing the possibility for the synthesis of novel organic compounds, assisting chemists in exploring the structure and properties of new substances, and promoting the continuous progress of organic chemistry theory and practice.
In conclusion, 1% 2C2% 2C3-tribromo-5- (tribromo-methyl) benzene plays a significant role in the fields of medicine, materials, and organic synthesis, and has a profound impact on the development of related industries.
What are the methods for preparing 1,2,3-trichloro-5- (trifluoromethyl) benzene?
To prepare 1,2,3-tribromo-5- (tribromo-methyl) benzene, the method is as follows:
First take an appropriate amount of benzene, place it in the reaction kettle, use iron filings as a catalyst, slowly add bromine, and control the temperature appropriately. This step is the substitution reaction between benzene and bromine to generate bromobenzene. The reaction is quite critical, and the temperature and catalyst dosage need to be precisely controlled. If the temperature is too high, side reactions will multiply and the product will be impure; if there is too little catalyst, the reaction will be delayed.
After obtaining bromobenzene, separate and purify it, then introduce a specific amount of iron bromide, and then introduce hydrogen bromide gas. At the same time, increase the temperature to promote the further bromination of bromobenzene and generate polybro In this process, it is necessary to pay close attention to the reaction process and monitor the degree of reaction by detection means to ensure that suitable polybrominated benzene products are generated.
Subsequently, a specific alkylation reagent, such as a reagent containing tribromo methyl, is alkylated with the above-mentioned polybrominated benzene under suitable reaction conditions. The reaction conditions in this step are strict, and there are requirements for the purity of the reagent, the pH of the reaction environment, and the temperature. It needs to be carried out in an anhydrous and oxygen-free environment to prevent side reactions from occurring.
After the reaction is completed, a series of separation and purification operations such as distillation, extraction, and recrystallization are used to remove impurities, and pure 1,2,3-tribromo-5- (tribromo methyl) benzene products can be obtained. Each step of separation and purification is related to the purity of the final product, and careful operation is required to obtain the ideal product.
First take an appropriate amount of benzene, place it in the reaction kettle, use iron filings as a catalyst, slowly add bromine, and control the temperature appropriately. This step is the substitution reaction between benzene and bromine to generate bromobenzene. The reaction is quite critical, and the temperature and catalyst dosage need to be precisely controlled. If the temperature is too high, side reactions will multiply and the product will be impure; if there is too little catalyst, the reaction will be delayed.
After obtaining bromobenzene, separate and purify it, then introduce a specific amount of iron bromide, and then introduce hydrogen bromide gas. At the same time, increase the temperature to promote the further bromination of bromobenzene and generate polybro In this process, it is necessary to pay close attention to the reaction process and monitor the degree of reaction by detection means to ensure that suitable polybrominated benzene products are generated.
Subsequently, a specific alkylation reagent, such as a reagent containing tribromo methyl, is alkylated with the above-mentioned polybrominated benzene under suitable reaction conditions. The reaction conditions in this step are strict, and there are requirements for the purity of the reagent, the pH of the reaction environment, and the temperature. It needs to be carried out in an anhydrous and oxygen-free environment to prevent side reactions from occurring.
After the reaction is completed, a series of separation and purification operations such as distillation, extraction, and recrystallization are used to remove impurities, and pure 1,2,3-tribromo-5- (tribromo methyl) benzene products can be obtained. Each step of separation and purification is related to the purity of the final product, and careful operation is required to obtain the ideal product.
What are the precautions for the use of 1,2,3-trichloro-5- (trifluoromethyl) benzene?
1% 2C2% 2C3-tribromo-5- (tribromo-methyl) benzene requires attention to many matters during use.
This substance is toxic and corrosive to a certain extent. Wear appropriate protective equipment during operation, such as protective gloves, goggles and protective clothing, etc., to avoid direct contact with the skin and eyes, and to prevent inhalation of its volatile gases, which may cause damage to the respiratory tract, skin and eyes.
In terms of storage, it should be placed in a cool, dry and well-ventilated place, away from fire, heat and oxidants. Due to its active nature, it may cause combustion or even explosion when exposed to heat, open flame or oxidants.
When using, it is necessary to operate in the fume hood to ensure good ventilation conditions, discharge volatile gases in time, and reduce the concentration of harmful substances in the air.
Furthermore, the waste generated by the use of this substance must be properly disposed of in accordance with relevant environmental regulations, and cannot be discarded at will to prevent pollution to the environment.
In addition, when taking the substance, precise control of the dosage is also extremely critical to avoid excessive use, which not only causes waste, but also increases the difficulty and risk of subsequent treatment. During the operation, it is also necessary to pay close attention to the reaction conditions, such as temperature, pressure, reaction time, etc., and strictly follow the operating procedures to ensure the safety and smoothness of the experiment or production process.
This substance is toxic and corrosive to a certain extent. Wear appropriate protective equipment during operation, such as protective gloves, goggles and protective clothing, etc., to avoid direct contact with the skin and eyes, and to prevent inhalation of its volatile gases, which may cause damage to the respiratory tract, skin and eyes.
In terms of storage, it should be placed in a cool, dry and well-ventilated place, away from fire, heat and oxidants. Due to its active nature, it may cause combustion or even explosion when exposed to heat, open flame or oxidants.
When using, it is necessary to operate in the fume hood to ensure good ventilation conditions, discharge volatile gases in time, and reduce the concentration of harmful substances in the air.
Furthermore, the waste generated by the use of this substance must be properly disposed of in accordance with relevant environmental regulations, and cannot be discarded at will to prevent pollution to the environment.
In addition, when taking the substance, precise control of the dosage is also extremely critical to avoid excessive use, which not only causes waste, but also increases the difficulty and risk of subsequent treatment. During the operation, it is also necessary to pay close attention to the reaction conditions, such as temperature, pressure, reaction time, etc., and strictly follow the operating procedures to ensure the safety and smoothness of the experiment or production process.
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