Linshang Chemical
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1,2,4-Trichloro-5-((4-Chlorophenyl)-Sulfonyl)Benzene
Linshang Chemical
|
HS Code |
161879 |
| Chemical Formula | C12H6Cl4O2S |
| Molecular Weight | 356.05 g/mol |
| Appearance | Solid (presumably, typical for such organic compounds) |
| Physical State At Room Temperature | Solid |
| Solubility In Water | Low (organic compound with hydrophobic aromatic and sulfonyl - chlorine groups) |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform (due to its non - polar and organic nature) |
As an accredited 1,2,4-Trichloro-5-((4-Chlorophenyl)-Sulfonyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500 - gram bottles containing 1,2,4 - trichloro - 5 - ((4 - chlorophenyl)sulfonyl)benzene. |
| Storage | 1,2,4 - trichloro - 5 - ((4 - chlorophenyl)sulfonyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and incompatible substances. Store in a tightly sealed container to prevent moisture and air exposure, which could potentially cause decomposition or reactivity issues. |
| Shipping | 1,2,4 - trichloro - 5 - ((4 - chlorophenyl)sulfonyl)benzene is a chemical. Shipping requires proper packaging in accordance with hazardous material regulations, likely in sealed, corrosion - resistant containers, with clear labeling for safe transport. |
Competitive 1,2,4-Trichloro-5-((4-Chlorophenyl)-Sulfonyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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Where to Buy 1,2,4-Trichloro-5-((4-Chlorophenyl)-Sulfonyl)Benzene in China?
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What are the main uses of 1,2,4-trichloro-5- ((4-chlorophenyl) sulfonyl) benzene?
The main uses of 1% 2C2% 2C4-trifluoro-5- ((4-fluorobenzyl) sulfonyl) benzyl are as follows:
This compound has important applications in the field of medicinal chemistry. Due to its unique chemical structure, the introduction of fluorine atoms can significantly change the physical and chemical properties of molecules, such as lipophilicity, stability, etc., thereby affecting their interaction with biological targets. In the process of drug development, this substance can be used as a key active fragment to construct drug molecules with specific biological activities. For example, due to its structural properties, it may have high affinity and selectivity for certain specific enzymes or receptors, which in turn lays the foundation for the development of innovative drugs for the treatment of specific diseases (such as cancer, neurological diseases, etc.).
In the field of materials science, 1% 2C2% 2C4-trifluoro-5- (4-fluorobenzyl) sulfonyl) benzyl also shows potential value. Due to its fluorine-containing group and sulfonyl group structure, it endows the material with unique properties. For example, its introduction into polymer materials can improve the chemical resistance, thermal stability and surface properties of the material. It can be used to prepare high-performance coating materials, electronic materials, etc., to meet the requirements of specific industrial scenarios for the special properties of materials.
In addition, in organic synthetic chemistry, it can act as an important synthesis intermediate. With the help of the activity check point in its molecular structure, a series of organic compounds with diverse structures can be derived through various organic chemical reactions, such as nucleophilic substitution reactions, coupling reactions, etc., providing organic synthesis chemists with rich structural modification possibilities, which helps to expand the library of organic compounds and promote the further development of organic synthesis chemistry.
This compound has important applications in the field of medicinal chemistry. Due to its unique chemical structure, the introduction of fluorine atoms can significantly change the physical and chemical properties of molecules, such as lipophilicity, stability, etc., thereby affecting their interaction with biological targets. In the process of drug development, this substance can be used as a key active fragment to construct drug molecules with specific biological activities. For example, due to its structural properties, it may have high affinity and selectivity for certain specific enzymes or receptors, which in turn lays the foundation for the development of innovative drugs for the treatment of specific diseases (such as cancer, neurological diseases, etc.).
In the field of materials science, 1% 2C2% 2C4-trifluoro-5- (4-fluorobenzyl) sulfonyl) benzyl also shows potential value. Due to its fluorine-containing group and sulfonyl group structure, it endows the material with unique properties. For example, its introduction into polymer materials can improve the chemical resistance, thermal stability and surface properties of the material. It can be used to prepare high-performance coating materials, electronic materials, etc., to meet the requirements of specific industrial scenarios for the special properties of materials.
In addition, in organic synthetic chemistry, it can act as an important synthesis intermediate. With the help of the activity check point in its molecular structure, a series of organic compounds with diverse structures can be derived through various organic chemical reactions, such as nucleophilic substitution reactions, coupling reactions, etc., providing organic synthesis chemists with rich structural modification possibilities, which helps to expand the library of organic compounds and promote the further development of organic synthesis chemistry.
What are the environmental effects of 1,2,4-trichloro-5- ((4-chlorophenyl) sulfonyl) benzene?
The environmental impact of 1% 2C2% 2C4-trifluoro-5- ((4-fluorobenzyl) phenolinyl) benzyl is a complex subject that needs to be investigated in detail.
This compound contains fluorine elements, and fluorine atoms can often significantly change the physical and chemical properties of molecules due to their special electronic structures. In the environment, fluorine-containing compounds are often highly stable, which may make them difficult to be rapidly degraded by microorganisms in the natural environment, and then remain in environmental media for a long time, such as soil, water, etc.
As far as the soil environment is concerned, the continuous accumulation of 1% 2C2% 2C4-trifluoro-5- (4-fluorobenzyl) phenyl) benzyl may affect the structure and function of soil microbial communities. Soil microorganisms play an indispensable role in many key ecological processes such as soil nutrient cycling and organic matter decomposition. The presence of this compound may inhibit the growth and metabolic activities of some beneficial microorganisms, disrupt the balance of soil ecosystems, and ultimately affect soil fertility and health.
In aquatic environments, it may also cause harm to aquatic organisms. Aquatic organisms are extremely sensitive to chemical substances, and this compound may be transmitted and enriched through the food chain, which may have adverse effects on the growth, reproduction and survival of aquatic organisms. For example, it may interfere with the endocrine system of aquatic organisms and affect their normal physiological development and behavior.
In addition, the migration and transformation process of this compound in the environment cannot be ignored. It may be transferred between different environmental media through surface runoff, groundwater flow, etc., thereby expanding the scope of its impact.
From a comprehensive perspective, 1% 2C2% 2C4-trifluoro-5- ((4-fluorobenzyl) phenyl) benzyl has a potential negative impact on the environment, and its environmental behavior and ecological effects need to be further studied in order to take appropriate measures for environmental threat and risk assessment and control.
This compound contains fluorine elements, and fluorine atoms can often significantly change the physical and chemical properties of molecules due to their special electronic structures. In the environment, fluorine-containing compounds are often highly stable, which may make them difficult to be rapidly degraded by microorganisms in the natural environment, and then remain in environmental media for a long time, such as soil, water, etc.
As far as the soil environment is concerned, the continuous accumulation of 1% 2C2% 2C4-trifluoro-5- (4-fluorobenzyl) phenyl) benzyl may affect the structure and function of soil microbial communities. Soil microorganisms play an indispensable role in many key ecological processes such as soil nutrient cycling and organic matter decomposition. The presence of this compound may inhibit the growth and metabolic activities of some beneficial microorganisms, disrupt the balance of soil ecosystems, and ultimately affect soil fertility and health.
In aquatic environments, it may also cause harm to aquatic organisms. Aquatic organisms are extremely sensitive to chemical substances, and this compound may be transmitted and enriched through the food chain, which may have adverse effects on the growth, reproduction and survival of aquatic organisms. For example, it may interfere with the endocrine system of aquatic organisms and affect their normal physiological development and behavior.
In addition, the migration and transformation process of this compound in the environment cannot be ignored. It may be transferred between different environmental media through surface runoff, groundwater flow, etc., thereby expanding the scope of its impact.
From a comprehensive perspective, 1% 2C2% 2C4-trifluoro-5- ((4-fluorobenzyl) phenyl) benzyl has a potential negative impact on the environment, and its environmental behavior and ecological effects need to be further studied in order to take appropriate measures for environmental threat and risk assessment and control.
What are the physical properties of 1,2,4-trichloro-5- ((4-chlorophenyl) sulfonyl) benzene
1% 2C2% 2C4-trihalo-5- (4-halobenzyl) cyano-benzyl) benzyl has more physical properties. The melting properties of this compound are characteristic, depending on the size, mesh and location of the element in the molecule. If the atomic weight of the element is large and the distribution in the molecule is favorable for the formation of dense crystals, the melting rate is often higher.
Its boiling rate is also affected by the molecular force. Due to the high performance of the atom, the molecular resistance can be increased, and the even-even force of the molecule can be increased, resulting in an increase in the boiling rate. And the molecule contains a cyano group, and the presence of a cyano group also increases the molecular force, which affects the boiling rate.
In terms of solubility, the solubility of the mixture is good in the soluble solution. Due to the fact that some groups in the molecule can be dissolved into water or other molecular forces, such as the nitrogen atom of the cyanyl group can be dissolved into water molecules. Therefore, there may be a certain solubility in some alcohols, ketones, etc. However, in the non-soluble solution, due to the mismatch between the molecular solubility and the non-soluble solution, the solubility is poor.
Density is also important for physical properties. Due to the large atomic weight of the atoms, the introduction of atoms increases the molecular density. And the density of the molecules also affects the density. If the molecular arrangement is dense, the density of the molecules is higher.
In addition, the refractive index of the molecules is also affected by the molecular density. The distribution of subclouds in different groups is different, resulting in the degree of deflection of the light transmission. Therefore, the physical properties of 1% 2C2% 2C4-trihalo-5- ((4-halobenzyl) cyanobenzyl) benzyl receptors The effects of each group, location and interaction in the molecule show the characteristics of diversification.
Its boiling rate is also affected by the molecular force. Due to the high performance of the atom, the molecular resistance can be increased, and the even-even force of the molecule can be increased, resulting in an increase in the boiling rate. And the molecule contains a cyano group, and the presence of a cyano group also increases the molecular force, which affects the boiling rate.
In terms of solubility, the solubility of the mixture is good in the soluble solution. Due to the fact that some groups in the molecule can be dissolved into water or other molecular forces, such as the nitrogen atom of the cyanyl group can be dissolved into water molecules. Therefore, there may be a certain solubility in some alcohols, ketones, etc. However, in the non-soluble solution, due to the mismatch between the molecular solubility and the non-soluble solution, the solubility is poor.
Density is also important for physical properties. Due to the large atomic weight of the atoms, the introduction of atoms increases the molecular density. And the density of the molecules also affects the density. If the molecular arrangement is dense, the density of the molecules is higher.
In addition, the refractive index of the molecules is also affected by the molecular density. The distribution of subclouds in different groups is different, resulting in the degree of deflection of the light transmission. Therefore, the physical properties of 1% 2C2% 2C4-trihalo-5- ((4-halobenzyl) cyanobenzyl) benzyl receptors The effects of each group, location and interaction in the molecule show the characteristics of diversification.
What are the chemical properties of 1,2,4-trichloro-5- ((4-chlorophenyl) sulfonyl) benzene
The chemical properties of 1% 2C2% 2C4-trifluoro-5- ((4-fluorobenzyl) phenolinyl) benzyl are as follows:
This compound has a large electronegativity of fluorine atoms, which can change the distribution of molecular electron clouds. In nucleophilic substitution reactions, the stability of carbon positive ions connected to fluorine atoms is affected, and the reactivity may be different from that of fluorine-free analogs. Its electron-absorbing effect also affects adjacent chemical bonds, such as reducing the density of aromatic electron clouds, reducing the activity of electrophilic substitution reactions, and the substitution positions are also affected, preferring meta-substitution. The benzyl group in the
molecule, the benzene ring can undergo typical benzene ring-related reactions, such as halogenation, nitration, sulfonation and other electrophilic substitution reactions. Under appropriate conditions, the benzyl carbon-carbon bond can undergo oxidation reaction to generate the corresponding aldehyde or carboxylic acid.
The phenolic group structure will endow the compound with unique electronic and spatial characteristics, which affect the overall conformation of the molecule and the reaction check point. Its nitrogen atom may participate in the coordination reaction or participate in the reaction as a nucleophilic check point.
Trifluoromethyl has strong electron absorption, which greatly affects the properties of molecular polarity and acidity, which enhances the acidity of the compound and also has a significant impact on its physical properties such as boiling point and solubility. In organic synthesis, this group can improve the stability and fat solubility of compounds, which is conducive to the penetration of drugs through biofilms in the field of medicinal chemistry.
Overall, this complex structure of compounds is rich in chemical properties, and has potential diverse uses and reactivity in the fields of organic synthesis, drug research and development due to the synergistic effect of various parts.
This compound has a large electronegativity of fluorine atoms, which can change the distribution of molecular electron clouds. In nucleophilic substitution reactions, the stability of carbon positive ions connected to fluorine atoms is affected, and the reactivity may be different from that of fluorine-free analogs. Its electron-absorbing effect also affects adjacent chemical bonds, such as reducing the density of aromatic electron clouds, reducing the activity of electrophilic substitution reactions, and the substitution positions are also affected, preferring meta-substitution. The benzyl group in the
molecule, the benzene ring can undergo typical benzene ring-related reactions, such as halogenation, nitration, sulfonation and other electrophilic substitution reactions. Under appropriate conditions, the benzyl carbon-carbon bond can undergo oxidation reaction to generate the corresponding aldehyde or carboxylic acid.
The phenolic group structure will endow the compound with unique electronic and spatial characteristics, which affect the overall conformation of the molecule and the reaction check point. Its nitrogen atom may participate in the coordination reaction or participate in the reaction as a nucleophilic check point.
Trifluoromethyl has strong electron absorption, which greatly affects the properties of molecular polarity and acidity, which enhances the acidity of the compound and also has a significant impact on its physical properties such as boiling point and solubility. In organic synthesis, this group can improve the stability and fat solubility of compounds, which is conducive to the penetration of drugs through biofilms in the field of medicinal chemistry.
Overall, this complex structure of compounds is rich in chemical properties, and has potential diverse uses and reactivity in the fields of organic synthesis, drug research and development due to the synergistic effect of various parts.
What are the precautions in the synthesis of 1,2,4-trichloro-5- ((4-chlorophenyl) sulfonyl) benzene?
1% 2C2% 2C4 -tribromo-5- ((4-bromobenzyl) sulfonyl) benzyl In the synthesis process, the following matters should be paid attention to:
First, the purity of the raw material is very important. All kinds of raw materials used in the synthesis of this compound must meet the purity standard. If the raw material is impure, impurities or participate in the reaction, resulting in the formation of by-products, interfering with the purity and yield of the target product. For example, if the 1,2,4-tribromo raw material contains other halogenated impurities, in the subsequent reaction or generate unexpected halogenated products, the product composition is complex, and the separation and purification difficulty is greatly increased.
Second, the reaction conditions must be precisely controlled. Temperature has a huge impact on the reaction, and different reaction steps need to be adapted to a specific temperature range. If the temperature is too high, the reaction rate will increase, but the side reactions may also intensify; if the temperature is too low, the reaction rate will be delayed, and the reaction may not be able to start. Taking a nucleophilic substitution reaction as an example, the temperature is not suitable, which may lead to incomplete substitution or the formation of elimination products. The reaction time cannot be ignored. If the time is too short, the reaction will not be fully carried out, and the yield will be affected. If the time is too long, it may cause problems such as product decomposition. At the same time, the pH of the reaction system also needs to be finely adjusted. Some reactions can only proceed smoothly under a specific pH environment, otherwise the reaction activity and selectivity will be affected.
Third, the choice of solvent is crucial. The appropriate solvent should be selected for different reaction steps, because it not only affects the solubility of the reactants, but also has an effect on the reaction rate and selectivity. Polar solvents and non-polar solvents have very different effects on ionic reactions and free radical reactions. For example, in a certain step of the reaction, polar solvents are conducive to the stability of ionic intermediates and the reaction progress, while non-polar solvents may make the reaction impossible or the rate is extremely slow.
Fourth, separation and purification need to be handled with caution. After the synthesis is completed, the product is often mixed with impurities such as unreacted raw materials, by-products and solvents. Appropriate separation and purification methods should be selected according to the physical and chemical properties of the products and impurities. Preliminary separation can be used by extraction method first, and then further purification can be carried out by column chromatography to obtain high-purity target The operation process should pay attention to mild conditions to avoid product loss or chemical changes.
Fifth, safety protection should not be underestimated. The synthesis process involves many chemical reagents, some of which are toxic, corrosive or flammable and explosive. If bromine is highly corrosive and toxic, it must be operated in a well-ventilated environment, wearing protective gloves, goggles and masks and other protective equipment, and strictly follow the operating procedures to take and use to prevent safety accidents.
First, the purity of the raw material is very important. All kinds of raw materials used in the synthesis of this compound must meet the purity standard. If the raw material is impure, impurities or participate in the reaction, resulting in the formation of by-products, interfering with the purity and yield of the target product. For example, if the 1,2,4-tribromo raw material contains other halogenated impurities, in the subsequent reaction or generate unexpected halogenated products, the product composition is complex, and the separation and purification difficulty is greatly increased.
Second, the reaction conditions must be precisely controlled. Temperature has a huge impact on the reaction, and different reaction steps need to be adapted to a specific temperature range. If the temperature is too high, the reaction rate will increase, but the side reactions may also intensify; if the temperature is too low, the reaction rate will be delayed, and the reaction may not be able to start. Taking a nucleophilic substitution reaction as an example, the temperature is not suitable, which may lead to incomplete substitution or the formation of elimination products. The reaction time cannot be ignored. If the time is too short, the reaction will not be fully carried out, and the yield will be affected. If the time is too long, it may cause problems such as product decomposition. At the same time, the pH of the reaction system also needs to be finely adjusted. Some reactions can only proceed smoothly under a specific pH environment, otherwise the reaction activity and selectivity will be affected.
Third, the choice of solvent is crucial. The appropriate solvent should be selected for different reaction steps, because it not only affects the solubility of the reactants, but also has an effect on the reaction rate and selectivity. Polar solvents and non-polar solvents have very different effects on ionic reactions and free radical reactions. For example, in a certain step of the reaction, polar solvents are conducive to the stability of ionic intermediates and the reaction progress, while non-polar solvents may make the reaction impossible or the rate is extremely slow.
Fourth, separation and purification need to be handled with caution. After the synthesis is completed, the product is often mixed with impurities such as unreacted raw materials, by-products and solvents. Appropriate separation and purification methods should be selected according to the physical and chemical properties of the products and impurities. Preliminary separation can be used by extraction method first, and then further purification can be carried out by column chromatography to obtain high-purity target The operation process should pay attention to mild conditions to avoid product loss or chemical changes.
Fifth, safety protection should not be underestimated. The synthesis process involves many chemical reagents, some of which are toxic, corrosive or flammable and explosive. If bromine is highly corrosive and toxic, it must be operated in a well-ventilated environment, wearing protective gloves, goggles and masks and other protective equipment, and strictly follow the operating procedures to take and use to prevent safety accidents.
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