Linshang Chemical
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1,2,4-Trichloro-5-Iodobenzene
Linshang Chemical
|
HS Code |
798965 |
| Chemical Formula | C6H2Cl3I |
| Molar Mass | 329.25 g/mol |
| Appearance | Solid (presumably, typical for many halogenated benzenes) |
| Melting Point | Data needed |
| Boiling Point | Data needed |
| Density | Data needed |
| Solubility In Water | Low (non - polar due to halogen substitution) |
| Solubility In Organic Solvents | Likely soluble in non - polar organic solvents like benzene, toluene |
| Vapor Pressure | Low (due to its relatively high molar mass and solid/liquid state at ambient conditions) |
| Stability | Stable under normal conditions, but can react under specific chemical reaction conditions like nucleophilic aromatic substitution |
As an accredited 1,2,4-Trichloro-5-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 1,2,4 - trichloro - 5 - iodobenzene packaged in a sealed glass bottle. |
| Storage | 1,2,4 - Trichloro - 5 - iodobenzene should be stored in a cool, dry, well - ventilated area away from sources of heat, ignition, and sunlight. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, strong acids, and bases to prevent potential chemical reactions. |
| Shipping | 1,2,4 - Trichloro - 5 - iodobenzene is shipped in sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, ensuring proper labeling, secure packaging to prevent leakage during transit. |
Competitive 1,2,4-Trichloro-5-Iodobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1,2,4-Trichloro-5-Iodobenzene in China?
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As a leading 1,2,4-Trichloro-5-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 1,2,4-trichloro-5-iodobenzene?
1%2C2%2C4-%E4%B8%89%E6%B0%AF-5-%E7%A2%98%E8%8B%AF%E7%9A%84%E5%8C%96%E5%AD%A6%E6%80%A7%E8%B4%A8%E5%A6%82%E4%B8%8B%EF%BC%9A
This compound is a white to light yellow crystalline solid with certain volatility and is stable at room temperature and pressure. In case of open flame, hot topic or strong oxidant, it may cause combustion and explosion.
Its melting point is in a specific range, and its boiling point also has a corresponding range. This physical property helps to separate and purify it under different conditions. In terms of solubility, it can be soluble in some organic solvents, such as poor water solubility. This property is of great significance in the extraction and reaction system construction of substances.
In terms of chemical activity, specific functional groups in its molecular structure determine its chemical behavior. Can participate in the substitution reaction. Under specific conditions, functional groups can be replaced by other atoms or groups to form new compounds. This reaction is often used in organic synthesis to introduce new functional groups to expand the variety of compounds. Addition reactions can also occur, which combine with specific reagents to change the molecular structure and properties, providing a way for the synthesis of complex organic molecules.
In redox reactions, it can be used as a reducing agent to provide electrons for other substances, and it is oxidized by itself, changing its own chemical structure and properties. In addition, due to its certain chemical stability, it can be stored for a long time under appropriate conditions, but care should be taken to avoid contact with incompatible substances to prevent accidental reactions. Its chemical properties make it potentially valuable in the fields of organic synthesis, medicinal chemistry, and materials science, and can be used as an intermediate to synthesize more complex compounds with specific functions.
This compound is a white to light yellow crystalline solid with certain volatility and is stable at room temperature and pressure. In case of open flame, hot topic or strong oxidant, it may cause combustion and explosion.
Its melting point is in a specific range, and its boiling point also has a corresponding range. This physical property helps to separate and purify it under different conditions. In terms of solubility, it can be soluble in some organic solvents, such as poor water solubility. This property is of great significance in the extraction and reaction system construction of substances.
In terms of chemical activity, specific functional groups in its molecular structure determine its chemical behavior. Can participate in the substitution reaction. Under specific conditions, functional groups can be replaced by other atoms or groups to form new compounds. This reaction is often used in organic synthesis to introduce new functional groups to expand the variety of compounds. Addition reactions can also occur, which combine with specific reagents to change the molecular structure and properties, providing a way for the synthesis of complex organic molecules.
In redox reactions, it can be used as a reducing agent to provide electrons for other substances, and it is oxidized by itself, changing its own chemical structure and properties. In addition, due to its certain chemical stability, it can be stored for a long time under appropriate conditions, but care should be taken to avoid contact with incompatible substances to prevent accidental reactions. Its chemical properties make it potentially valuable in the fields of organic synthesis, medicinal chemistry, and materials science, and can be used as an intermediate to synthesize more complex compounds with specific functions.
What are the main uses of 1,2,4-trichloro-5-iodobenzene?
1,2,4-Trifluoro-5-chlorobenzonitrile is a crucial intermediate in the field of organic synthesis, and has a wide range of uses in various industries such as medicine, pesticides, and materials.
In the field of medicine, it is often used as a key intermediate in the synthesis of many drugs. For example, some compounds with special biological activities, 1,2,4-trifluoro-5-chlorobenzonitrile, can be introduced into the molecular structure of drugs through specific chemical reactions, thereby endowing drugs with unique pharmacological activities and therapeutic effects. Like the development of some anti-tumor drugs, this compound may participate in it. By modifying and modifying its structure, the drug can more accurately act on the target of tumor cells and effectively inhibit the growth and proliferation of tumor cells.
In terms of pesticides, 1,2,4-trifluoro-5-chlorobenzonitrile is also an important synthetic raw material. Many new and efficient pesticides will be used in the creation of it, and through a series of chemical synthesis steps, pesticide products with excellent insecticidal, bactericidal or herbicidal properties can be prepared. Due to the presence of fluorine and chlorine atoms in its structure, it can significantly enhance the biological activity and environmental stability of pesticides, enhance the control effect of pesticides on harmful organisms, and prolong their shelf life in the environment.
In the materials industry, this compound can also play a key role. For example, in the synthesis of special polymer materials, 1,2,4-trifluoro-5-chlorobenzonitrile can be used as a functional monomer to participate in the polymerization reaction, introducing fluorine and chlorine-containing structural units into the polymer materials, thereby imparting special properties such as excellent thermal stability, chemical stability and corrosion resistance to the materials. These special polymer materials can be used in high-end fields such as aerospace, electronics and electrical appliances to meet the strict requirements for high performance of materials in related fields.
In summary, 1,2,4-trifluoro-5-chlorobenzonitrile, with its unique chemical structure, plays an indispensable role in many industries such as medicine, pesticides, and materials, and is of great significance in promoting technological progress and product innovation in various industries.
In the field of medicine, it is often used as a key intermediate in the synthesis of many drugs. For example, some compounds with special biological activities, 1,2,4-trifluoro-5-chlorobenzonitrile, can be introduced into the molecular structure of drugs through specific chemical reactions, thereby endowing drugs with unique pharmacological activities and therapeutic effects. Like the development of some anti-tumor drugs, this compound may participate in it. By modifying and modifying its structure, the drug can more accurately act on the target of tumor cells and effectively inhibit the growth and proliferation of tumor cells.
In terms of pesticides, 1,2,4-trifluoro-5-chlorobenzonitrile is also an important synthetic raw material. Many new and efficient pesticides will be used in the creation of it, and through a series of chemical synthesis steps, pesticide products with excellent insecticidal, bactericidal or herbicidal properties can be prepared. Due to the presence of fluorine and chlorine atoms in its structure, it can significantly enhance the biological activity and environmental stability of pesticides, enhance the control effect of pesticides on harmful organisms, and prolong their shelf life in the environment.
In the materials industry, this compound can also play a key role. For example, in the synthesis of special polymer materials, 1,2,4-trifluoro-5-chlorobenzonitrile can be used as a functional monomer to participate in the polymerization reaction, introducing fluorine and chlorine-containing structural units into the polymer materials, thereby imparting special properties such as excellent thermal stability, chemical stability and corrosion resistance to the materials. These special polymer materials can be used in high-end fields such as aerospace, electronics and electrical appliances to meet the strict requirements for high performance of materials in related fields.
In summary, 1,2,4-trifluoro-5-chlorobenzonitrile, with its unique chemical structure, plays an indispensable role in many industries such as medicine, pesticides, and materials, and is of great significance in promoting technological progress and product innovation in various industries.
What are the preparation methods of 1,2,4-trichloro-5-iodobenzene?
1%2C2%2C4-%E4%B8%89%E6%B0%AF-5-%E7%A2%98%E8%8B%AF is 1,2,4-trifluoro-5-chlorobenzene, and there are many preparation methods. The following are described in detail:
1. ** Halogenation reaction method **:
- With benzene as the initial raw material, the chlorination process is first carried out. Under the help of a specific temperature and a catalyst (such as ferric chloride), chlorine atoms ingeniously replace hydrogen atoms on the benzene ring to generate chlorobenzene. Then, under appropriate conditions, fluorine atoms are carefully introduced to realize the fluorination reaction of p-chlorobenzene, and then 1,2,4-trifluoro-5-chlorobenzene is obtained. This route is common and easy to obtain, but the reaction steps are slightly complicated, and the reaction conditions of each step need to be precisely controlled.
- For example, benzene and chlorine are first introduced into a reactor containing ferric trichloride in a certain proportion, and the temperature is maintained at 40-60 ° C to fully react to form chlorobenzene. Then select a suitable fluorinated reagent, such as potassium fluoride, and react with chlorobenzene in the presence of an organic solvent and catalyst. After careful separation and purification, the final product is obtained.
2. ** Diazotization Reaction Method **:
- Starting from the corresponding amino compound, by means of diazotization reaction, the amino group is first converted into a diazonium salt. Subsequently, under the action of a specific reagent, the diazonium group is replaced by a fluorine atom and a chlorine atom to achieve the preparation of 1,2,4-trifluoro-5-chlorobenzene. This method has good reaction selectivity and high product purity, but it is difficult to prepare or store the raw material amino compound.
- During the specific operation, the amino-containing benzene derivative is dissolved in an appropriate amount of acid, cooled to 0-5 ° C, and the sodium nitrite solution is slowly added dropwise to complete the diazotization reaction. After that, fluorine source and chlorine source reagents are added to promote the substitution of diazo groups. Pure 1,2,4-trifluoro-5-chlorobenzene can be obtained through extraction, distillation and other processes.
3. ** Coupling reaction method of aryl halides **:
- Select suitable halogenated aromatics and couple them with fluorine and chlorine-containing reagents under the action of catalysts. This approach can efficiently construct carbon-halogen bonds, and the reaction conditions are relatively mild, but the catalyst requirements are high, and the cost or consideration factors.
- For example, using halogenated benzene derivatives and fluorinated and chlorinated reagents as raw materials, in the presence of palladium catalysts and ligands, heat the reaction in an organic solvent, and separate and purify to obtain 1,2,4-trifluoro-5-chlorobenzene.
1. ** Halogenation reaction method **:
- With benzene as the initial raw material, the chlorination process is first carried out. Under the help of a specific temperature and a catalyst (such as ferric chloride), chlorine atoms ingeniously replace hydrogen atoms on the benzene ring to generate chlorobenzene. Then, under appropriate conditions, fluorine atoms are carefully introduced to realize the fluorination reaction of p-chlorobenzene, and then 1,2,4-trifluoro-5-chlorobenzene is obtained. This route is common and easy to obtain, but the reaction steps are slightly complicated, and the reaction conditions of each step need to be precisely controlled.
- For example, benzene and chlorine are first introduced into a reactor containing ferric trichloride in a certain proportion, and the temperature is maintained at 40-60 ° C to fully react to form chlorobenzene. Then select a suitable fluorinated reagent, such as potassium fluoride, and react with chlorobenzene in the presence of an organic solvent and catalyst. After careful separation and purification, the final product is obtained.
2. ** Diazotization Reaction Method **:
- Starting from the corresponding amino compound, by means of diazotization reaction, the amino group is first converted into a diazonium salt. Subsequently, under the action of a specific reagent, the diazonium group is replaced by a fluorine atom and a chlorine atom to achieve the preparation of 1,2,4-trifluoro-5-chlorobenzene. This method has good reaction selectivity and high product purity, but it is difficult to prepare or store the raw material amino compound.
- During the specific operation, the amino-containing benzene derivative is dissolved in an appropriate amount of acid, cooled to 0-5 ° C, and the sodium nitrite solution is slowly added dropwise to complete the diazotization reaction. After that, fluorine source and chlorine source reagents are added to promote the substitution of diazo groups. Pure 1,2,4-trifluoro-5-chlorobenzene can be obtained through extraction, distillation and other processes.
3. ** Coupling reaction method of aryl halides **:
- Select suitable halogenated aromatics and couple them with fluorine and chlorine-containing reagents under the action of catalysts. This approach can efficiently construct carbon-halogen bonds, and the reaction conditions are relatively mild, but the catalyst requirements are high, and the cost or consideration factors.
- For example, using halogenated benzene derivatives and fluorinated and chlorinated reagents as raw materials, in the presence of palladium catalysts and ligands, heat the reaction in an organic solvent, and separate and purify to obtain 1,2,4-trifluoro-5-chlorobenzene.
What should I pay attention to when storing and transporting 1,2,4-trichloro-5-iodobenzene?
1%2C2%2C4-%E4%B8%89%E6%B0%AF-5-%E7%A2%98%E8%8B%AF, it is a rare medicine. When storing and transporting, many matters need to be paid attention to carefully.
When storing, the temperature and humidity of the environment should be the first priority. This medicine should be stored in a cool and dry place, the temperature should not exceed 20 degrees Celsius, and the humidity should also be controlled in a suitable area. If the temperature and humidity are too high, the composition of the medicine may change, resulting in damage to the efficacy of the medicine. For example, if it is placed in a hot and humid place, its properties may change after a while, and the efficacy of the medicine will attenuate.
The second is the protection of light. 1%2C2%2C4-%E4%B8%89%E6%B0%AF-5-%E7%A2%98%E8%8B%AF afraid of light, strong light shines for a long time, which is easy to cause its chemical changes. Therefore, it should be stored in an opaque container or stored in a dark room to prevent light erosion.
Furthermore, the storage place should be clean and odor-free. If the medicine coexists with odorous substances, it may stain the odor, or react with other substances, endangering the quality of the medicine.
As for transportation, the packaging must be sturdy. When properly wrapped with shockproof and moisture-proof materials, it will not be bumped and collided on the way, causing damage to the container and damage to the medicine. During transportation, the control of temperature and humidity should not be ignored. It is necessary to maintain the environment with suitable equipment according to the requirements of storage. And when handling, handle it with care and do not treat it rudely.
In short, the storage and transportation of 1%2C2%2C4-%E4%B8%89%E6%B0%AF-5-%E7%A2%98%E8%8B%AF is related to the effectiveness of the medicine. Every step must be carried out strictly. If there is a slight mistake, or a big mistake is made.
When storing, the temperature and humidity of the environment should be the first priority. This medicine should be stored in a cool and dry place, the temperature should not exceed 20 degrees Celsius, and the humidity should also be controlled in a suitable area. If the temperature and humidity are too high, the composition of the medicine may change, resulting in damage to the efficacy of the medicine. For example, if it is placed in a hot and humid place, its properties may change after a while, and the efficacy of the medicine will attenuate.
The second is the protection of light. 1%2C2%2C4-%E4%B8%89%E6%B0%AF-5-%E7%A2%98%E8%8B%AF afraid of light, strong light shines for a long time, which is easy to cause its chemical changes. Therefore, it should be stored in an opaque container or stored in a dark room to prevent light erosion.
Furthermore, the storage place should be clean and odor-free. If the medicine coexists with odorous substances, it may stain the odor, or react with other substances, endangering the quality of the medicine.
As for transportation, the packaging must be sturdy. When properly wrapped with shockproof and moisture-proof materials, it will not be bumped and collided on the way, causing damage to the container and damage to the medicine. During transportation, the control of temperature and humidity should not be ignored. It is necessary to maintain the environment with suitable equipment according to the requirements of storage. And when handling, handle it with care and do not treat it rudely.
In short, the storage and transportation of 1%2C2%2C4-%E4%B8%89%E6%B0%AF-5-%E7%A2%98%E8%8B%AF is related to the effectiveness of the medicine. Every step must be carried out strictly. If there is a slight mistake, or a big mistake is made.
What are the effects of 1,2,4-trichloro-5-iodobenzene on the environment and human health?
1%2C2%2C4-%E4%B8%89%E6%B0%AF-5-%E7%A2%98%E8%8B%AF, this substance has a considerable impact on the human environment and human health.
At one end of the environment, its biological stability is difficult to degrade, so it is easy to accumulate in the environment. If released in water bodies, it will migrate with water flow, causing pollution to surrounding waters, and aquatic organisms bear the brunt. After aquatic plants absorb this substance, their physiological functions may be disrupted, growth and development will be hindered, such as reduced photosynthesis efficiency, short and thin plants, etc. Aquatic animals accidentally eat food containing this substance, or cause reproductive system disorders, decreased reproductive capacity, and population numbers will also be reduced. And because it can be enriched through the food chain, organisms at the high end of the food chain have extremely high concentrations of this substance in their bodies, which seriously threatens the ecological balance.
As for human health, it can invade the human body in a variety of ways. Breathing air containing this pollutant, or coming into contact with contaminated soil, water, or even eating contaminated food, all have this risk. After entering the human body, it will interfere with the endocrine system. For example, it can imitate or antagonize the action of human natural hormones, affect hormone signaling pathways, and then interfere with normal physiological functions of the human body. Long-term exposure to this substance environment increases the risk of certain diseases, such as cancer, especially endocrine-related cancers such as breast cancer and prostate cancer. It may also cause damage to the nervous system, causing people to experience memory loss, inattention, mood swings and other symptoms, which seriously affect the quality of life and work efficiency. In short, the impact of 1%2C2%2C4-%E4%B8%89%E6%B0%AF-5-%E7%A2%98%E8%8B%AF on the environment and human health cannot be underestimated, and it needs to be paid attention to and properly dealt with.
At one end of the environment, its biological stability is difficult to degrade, so it is easy to accumulate in the environment. If released in water bodies, it will migrate with water flow, causing pollution to surrounding waters, and aquatic organisms bear the brunt. After aquatic plants absorb this substance, their physiological functions may be disrupted, growth and development will be hindered, such as reduced photosynthesis efficiency, short and thin plants, etc. Aquatic animals accidentally eat food containing this substance, or cause reproductive system disorders, decreased reproductive capacity, and population numbers will also be reduced. And because it can be enriched through the food chain, organisms at the high end of the food chain have extremely high concentrations of this substance in their bodies, which seriously threatens the ecological balance.
As for human health, it can invade the human body in a variety of ways. Breathing air containing this pollutant, or coming into contact with contaminated soil, water, or even eating contaminated food, all have this risk. After entering the human body, it will interfere with the endocrine system. For example, it can imitate or antagonize the action of human natural hormones, affect hormone signaling pathways, and then interfere with normal physiological functions of the human body. Long-term exposure to this substance environment increases the risk of certain diseases, such as cancer, especially endocrine-related cancers such as breast cancer and prostate cancer. It may also cause damage to the nervous system, causing people to experience memory loss, inattention, mood swings and other symptoms, which seriously affect the quality of life and work efficiency. In short, the impact of 1%2C2%2C4-%E4%B8%89%E6%B0%AF-5-%E7%A2%98%E8%8B%AF on the environment and human health cannot be underestimated, and it needs to be paid attention to and properly dealt with.
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