Linshang Chemical
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1,2-Bis(Chloromethyl)Benzene
Linshang Chemical
|
HS Code |
942217 |
| Chemical Formula | C8H8Cl2 |
| Molar Mass | 175.055 g/mol |
| Appearance | Colorless to light - yellow liquid |
| Odor | Pungent odor |
| Density | 1.25 g/cm³ (approximate) |
| Boiling Point | 215 - 217 °C |
| Melting Point | - 4 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like benzene, toluene |
| Flash Point | 97 °C |
| Vapor Pressure | Low vapor pressure at room temperature |
| Stability | Stable under normal conditions but can react with strong oxidizing agents |
As an accredited 1,2-Bis(Chloromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 1,2 - bis(chloromethyl)benzene packaged in a sealed, corrosion - resistant bottle. |
| Storage | 1,2 - bis(chloromethyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames due to its flammability. Keep it in a tightly sealed container to prevent leakage and exposure to air or moisture. Store it separately from oxidizing agents and reactive chemicals to avoid potential chemical reactions. |
| Shipping | 1,2 - bis(chloromethyl)benzene is a hazardous chemical. It should be shipped in accordance with strict regulations, using specialized containers. Ensure proper labeling, secure packaging, and compliance with transportation safety standards to prevent spills and risks. |
Competitive 1,2-Bis(Chloromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1,2-Bis(Chloromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1,2-bis (chloromethyl) benzene?
1% 2C2 -Bis (methoxy) naphthalene, this substance may have special use in ancient prescription skills and alchemy. It can be used to refine secret medicines to help practitioners reconcile internal qi and strengthen the essence. In the art of Dan Cauldron, it is often used as a medicinal guide to guide the power of various medicines to reach the depths of the meridians and collaterals, so that the effect of the medicine is better.
In ancient times, there were also craftsmen who used it as a basis to make special things, or as a wonderful agent to help the operation of the instrument. Because of its unique nature, after specific processing, it can make the joints of the instrument flexible, reduce the power of friction, and will not be damaged for a long time.
However, this substance is also toxic. If used improperly, it will hurt itself. Therefore, when the ancients used it, they must follow the inheritance of the sect, abide by the law, first use special methods to remove its toxicity, and then use it. When taking medicine, you need to check your own yin and yang, and act according to the symptoms. Don't be rash.
In short, 1% 2C2-bis (methoxy) naphthalene has wonderful uses in ancient alchemy and craftsmanship, but those who use it need to be well aware of its nature and control it with ancient methods to obtain its benefits and avoid its harm.
In ancient times, there were also craftsmen who used it as a basis to make special things, or as a wonderful agent to help the operation of the instrument. Because of its unique nature, after specific processing, it can make the joints of the instrument flexible, reduce the power of friction, and will not be damaged for a long time.
However, this substance is also toxic. If used improperly, it will hurt itself. Therefore, when the ancients used it, they must follow the inheritance of the sect, abide by the law, first use special methods to remove its toxicity, and then use it. When taking medicine, you need to check your own yin and yang, and act according to the symptoms. Don't be rash.
In short, 1% 2C2-bis (methoxy) naphthalene has wonderful uses in ancient alchemy and craftsmanship, but those who use it need to be well aware of its nature and control it with ancient methods to obtain its benefits and avoid its harm.
What are the physical properties of 1,2-bis (chloromethyl) benzene?
1% 2C2-bis (methoxy) benzene, also known as phthalene, is an organic compound. Its physical properties are described as follows:
- ** Properties **: Under normal temperature and pressure, this substance is colorless to light yellow liquid. It is clear and transparent in appearance, and has a unique aromatic odor, which can be identified by smell.
- ** Melting point **: Its melting point is -18 ° C. When the temperature drops to this point and below, 1% 2C2-bis (methoxy) benzene will gradually change from liquid to solid.
- ** Boiling point **: The boiling point reaches 206 ° C. If it is heated, when the temperature rises to 206 ° C, the substance will rapidly change from liquid to gaseous state, causing violent vaporization.
- ** Density **: The density is about 1.08 g/cm ³. Compared with water, the density of 1% 2C2 - bis (methoxy) benzene is slightly higher than that of water, so when mixed with water, it will settle at the bottom.
- ** Solubility **: The substance is insoluble in water. Due to the characteristics of its molecular structure, the force between it and water molecules is weak, and it cannot be effectively dispersed in water. However, it is soluble in many organic solvents, such as ethanol, ether, acetone, etc., and can be uniformly dispersed in these organic solvents to form a stable solution system.
- ** Volatility **: 1% 2C2 - Bis (methoxy) benzene has a certain volatility. At room temperature, it will slowly change from liquid to gaseous and dissipate in the air, but its volatility is not extremely strong and relatively stable.
- ** Properties **: Under normal temperature and pressure, this substance is colorless to light yellow liquid. It is clear and transparent in appearance, and has a unique aromatic odor, which can be identified by smell.
- ** Melting point **: Its melting point is -18 ° C. When the temperature drops to this point and below, 1% 2C2-bis (methoxy) benzene will gradually change from liquid to solid.
- ** Boiling point **: The boiling point reaches 206 ° C. If it is heated, when the temperature rises to 206 ° C, the substance will rapidly change from liquid to gaseous state, causing violent vaporization.
- ** Density **: The density is about 1.08 g/cm ³. Compared with water, the density of 1% 2C2 - bis (methoxy) benzene is slightly higher than that of water, so when mixed with water, it will settle at the bottom.
- ** Solubility **: The substance is insoluble in water. Due to the characteristics of its molecular structure, the force between it and water molecules is weak, and it cannot be effectively dispersed in water. However, it is soluble in many organic solvents, such as ethanol, ether, acetone, etc., and can be uniformly dispersed in these organic solvents to form a stable solution system.
- ** Volatility **: 1% 2C2 - Bis (methoxy) benzene has a certain volatility. At room temperature, it will slowly change from liquid to gaseous and dissipate in the air, but its volatility is not extremely strong and relatively stable.
What are the chemical properties of 1,2-bis (chloromethyl) benzene?
1% 2C2-bis (methoxymethyl) benzene, its chemical properties are quite specific. Among this substance, the benzene ring is its main frame, and at the 1st and 2nd positions of the benzene ring, there are bis (methoxymethyl) groups connected. This structure causes it to exhibit many unique properties.
Discussing physical properties, 1% 2C2-bis (methoxymethyl) benzene is mostly liquid at room temperature, with specific boiling points and melting points. Due to the conjugated system of benzene rings in the molecule, it absorbs light of specific wavelengths, and the characteristic absorption peak can be found in the ultraviolet spectrum. In terms of chemical properties, the benzene ring attached to methoxy methyl group increases the electron cloud density of the benzene ring due to the electron-giving effect of methoxy group, and the activity of electrophilic substitution reaction is enhanced. In case of halogenated reagents, halogenation reactions are prone to occur, and halogen atoms can selectively replace the positions with higher electron cloud density on the benzene ring. In addition, in methoxy methyl group, oxygen atoms have lone pairs of electrons, which can participate in coordination reactions and form complexes with metal ions. In addition, the α-hydrogen of methoxy group has certain activity, and in a strong alkali environment, related reactions can occur, or the rearrangement and transformation of molecular structure can be caused. And methoxy methyl group can be hydrolyzed under specific conditions to generate corresponding products such as alcohol and formaldehyde.
Furthermore, 1% 2C2 -bis (methoxymethyl) benzene is widely used in the field of organic synthesis, and can be used as a key intermediate to construct complex organic molecular structures through a series of reactions. It has important applications in pharmaceutical chemistry, materials science and other fields.
Discussing physical properties, 1% 2C2-bis (methoxymethyl) benzene is mostly liquid at room temperature, with specific boiling points and melting points. Due to the conjugated system of benzene rings in the molecule, it absorbs light of specific wavelengths, and the characteristic absorption peak can be found in the ultraviolet spectrum. In terms of chemical properties, the benzene ring attached to methoxy methyl group increases the electron cloud density of the benzene ring due to the electron-giving effect of methoxy group, and the activity of electrophilic substitution reaction is enhanced. In case of halogenated reagents, halogenation reactions are prone to occur, and halogen atoms can selectively replace the positions with higher electron cloud density on the benzene ring. In addition, in methoxy methyl group, oxygen atoms have lone pairs of electrons, which can participate in coordination reactions and form complexes with metal ions. In addition, the α-hydrogen of methoxy group has certain activity, and in a strong alkali environment, related reactions can occur, or the rearrangement and transformation of molecular structure can be caused. And methoxy methyl group can be hydrolyzed under specific conditions to generate corresponding products such as alcohol and formaldehyde.
Furthermore, 1% 2C2 -bis (methoxymethyl) benzene is widely used in the field of organic synthesis, and can be used as a key intermediate to construct complex organic molecular structures through a series of reactions. It has important applications in pharmaceutical chemistry, materials science and other fields.
What are the synthesis methods of 1,2-bis (chloromethyl) benzene?
The common methods for synthesizing 1% 2C2-bis (methoxymethyl) benzene are as follows:
First, benzene is used as the starting material by Fu-gram alkylation reaction. First, benzene is reacted with chloromethyl methyl ether under the catalysis of Lewis acid (such as anhydrous aluminum trichloride). In this process, Lewis acid activates chloromethyl methyl ether to generate carbon positive ions, which then undergoes electrophilic substitution with the benzene ring to obtain 1% 2C2-bis (methoxymethyl) benzene. The raw materials of this method are easy to obtain, and the operation is not complicated. However, the reaction conditions are relatively harsh, and Lewis acid is highly susceptible to deactivation in contact with water, so the reaction system needs to be strictly anhydrous.
Second, you can start from o-xylene. First, o-xylene is halogenated, and N-bromosuccinimide (NBS) is used as a bromination reagent. Under the action of light or initiator, the methyl of o-xylene is brominated to obtain o-di (bromo-methyl) benzene. Then, this product is reacted with sodium methoxide, and the bromine atom is replaced by methoxy to obtain 1% 2C2-bis (methoxy-methyl) benzene. This path has a little more steps, but the reaction selectivity of each step is good and the yield is considerable.
Third, phthalaldehyde is used as the raw material. First, phthalaldehyde is reduced to phthalol, and sodium borohydride isothermal and reducing agent can be selected. Afterwards, phthalol reacts with chloromethyl methyl ether under alkaline conditions, and the hydroxyl group is replaced by methoxy methyl to form the target product 1% 2C2-bis (methoxy methyl) benzene. The raw materials of this method are relatively special, but the synthesis route is relatively direct, and the requirements for reaction equipment are not high.
The above synthesis methods have their own advantages and disadvantages. In practical application, it is necessary to comprehensively consider many factors such as raw material availability, cost, reaction conditions and product purity, and make a prudent choice.
First, benzene is used as the starting material by Fu-gram alkylation reaction. First, benzene is reacted with chloromethyl methyl ether under the catalysis of Lewis acid (such as anhydrous aluminum trichloride). In this process, Lewis acid activates chloromethyl methyl ether to generate carbon positive ions, which then undergoes electrophilic substitution with the benzene ring to obtain 1% 2C2-bis (methoxymethyl) benzene. The raw materials of this method are easy to obtain, and the operation is not complicated. However, the reaction conditions are relatively harsh, and Lewis acid is highly susceptible to deactivation in contact with water, so the reaction system needs to be strictly anhydrous.
Second, you can start from o-xylene. First, o-xylene is halogenated, and N-bromosuccinimide (NBS) is used as a bromination reagent. Under the action of light or initiator, the methyl of o-xylene is brominated to obtain o-di (bromo-methyl) benzene. Then, this product is reacted with sodium methoxide, and the bromine atom is replaced by methoxy to obtain 1% 2C2-bis (methoxy-methyl) benzene. This path has a little more steps, but the reaction selectivity of each step is good and the yield is considerable.
Third, phthalaldehyde is used as the raw material. First, phthalaldehyde is reduced to phthalol, and sodium borohydride isothermal and reducing agent can be selected. Afterwards, phthalol reacts with chloromethyl methyl ether under alkaline conditions, and the hydroxyl group is replaced by methoxy methyl to form the target product 1% 2C2-bis (methoxy methyl) benzene. The raw materials of this method are relatively special, but the synthesis route is relatively direct, and the requirements for reaction equipment are not high.
The above synthesis methods have their own advantages and disadvantages. In practical application, it is necessary to comprehensively consider many factors such as raw material availability, cost, reaction conditions and product purity, and make a prudent choice.
What are the precautions for using 1,2-bis (chloromethyl) benzene?
1% 2C2 -bis (methoxymethyl) benzene, this substance has many points to pay attention to during use.
First, it is related to safety. This substance is flammable to a certain extent. When storing and using, it is necessary to keep away from fire sources such as open flames and hot topics. For example, smoking is strictly prohibited in the operation site. Strictly follow the approval process and take corresponding protective measures before working on fire. At the same time, if you accidentally come into contact with the skin or eyes, you should immediately rinse with a large amount of flowing water. If the contact area is large or there is still discomfort after rinsing, you need to seek medical attention as soon as possible. If inhaling its volatile gas causes respiratory discomfort, you should quickly move to a fresh air place to keep breathing smoothly. If necessary, you need to seek medical attention.
Second, in terms of storage. It should be stored in a cool and well-ventilated place, away from oxidants and other substances that will react with it. The storage container must be tightly sealed to prevent leakage. The temperature and humidity of the storage environment should also be controlled to avoid improper temperature and humidity affecting its stability.
Third, the operation process. During operation, ensure that the site is well ventilated, and volatile gases can be discharged with the help of ventilation equipment. Operators need to wear appropriate protective equipment, such as protective gloves, protective glasses and gas masks, to prevent contact and inhalation. Moreover, the operation process should be strictly standardized to avoid leakage due to operation errors.
Fourth, transportation. During transportation, ensure that the container is stable to prevent collisions and bumps from causing leakage. Transportation vehicles need to be equipped with corresponding emergency treatment equipment and protective equipment, and transportation personnel should also be familiar with emergency treatment methods.
Only when using 1% 2C2-bis (methoxymethyl) benzene, careful attention to the above matters can effectively avoid risks and ensure personnel safety and environmental safety.
First, it is related to safety. This substance is flammable to a certain extent. When storing and using, it is necessary to keep away from fire sources such as open flames and hot topics. For example, smoking is strictly prohibited in the operation site. Strictly follow the approval process and take corresponding protective measures before working on fire. At the same time, if you accidentally come into contact with the skin or eyes, you should immediately rinse with a large amount of flowing water. If the contact area is large or there is still discomfort after rinsing, you need to seek medical attention as soon as possible. If inhaling its volatile gas causes respiratory discomfort, you should quickly move to a fresh air place to keep breathing smoothly. If necessary, you need to seek medical attention.
Second, in terms of storage. It should be stored in a cool and well-ventilated place, away from oxidants and other substances that will react with it. The storage container must be tightly sealed to prevent leakage. The temperature and humidity of the storage environment should also be controlled to avoid improper temperature and humidity affecting its stability.
Third, the operation process. During operation, ensure that the site is well ventilated, and volatile gases can be discharged with the help of ventilation equipment. Operators need to wear appropriate protective equipment, such as protective gloves, protective glasses and gas masks, to prevent contact and inhalation. Moreover, the operation process should be strictly standardized to avoid leakage due to operation errors.
Fourth, transportation. During transportation, ensure that the container is stable to prevent collisions and bumps from causing leakage. Transportation vehicles need to be equipped with corresponding emergency treatment equipment and protective equipment, and transportation personnel should also be familiar with emergency treatment methods.
Only when using 1% 2C2-bis (methoxymethyl) benzene, careful attention to the above matters can effectively avoid risks and ensure personnel safety and environmental safety.
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