Linshang Chemical
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1-(2-Bromoethyl)-4-Chlorobenzene
Linshang Chemical
|
HS Code |
391285 |
| Chemical Formula | C8H8BrCl |
| Molecular Weight | 221.506 g/mol |
| Appearance | Typically a colorless to light - colored liquid |
| Boiling Point | Approximately in the range of 230 - 240 °C (estimated, actual may vary based on purity) |
| Density | Around 1.5 - 1.6 g/cm³ (estimated) |
| Solubility In Water | Insoluble in water due to its non - polar nature |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, diethyl ether, and chloroform |
| Flash Point | Relatively high, estimated around 100 - 110 °C |
| Vapor Pressure | Low vapor pressure at room temperature |
As an accredited 1-(2-Bromoethyl)-4-Chlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 g of 1-(2 - bromoethyl)-4 - chlorobenzene packaged in a sealed glass bottle. |
| Storage | 1-(2 - bromoethyl)-4 - chlorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container to prevent vapor leakage. It is advisable to store it separately from incompatible substances to avoid potential chemical reactions. Use appropriate storage cabinets or areas designated for hazardous chemicals. |
| Shipping | 1-(2 - bromoethyl)-4 - chlorobenzene is shipped in sealed, corrosion - resistant containers. Shipment follows strict chemical transport regulations to ensure safety during transit, protecting from physical damage and environmental exposure. |
Competitive 1-(2-Bromoethyl)-4-Chlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-(2-Bromoethyl)-4-Chlorobenzene in China?
As a trusted 1-(2-Bromoethyl)-4-Chlorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-(2-Bromoethyl)-4-Chlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 1- (2-bromoethyl) -4-chlorobenzene?
1 - (2 -hydroxyethyl) -4 -methoxybenzene, this substance has unique properties. Its color is colorless to light yellow liquid, like the shimmer through the mist in the morning, with its own unique clear texture.
Smell it, the smell emitted is relatively mild, not as flamboyant as some pungent substances, but with a faint and faint special smell, just like a fragrance hidden in the depths of the forest.
In terms of solubility, it shows good compatibility in organic solvents, just like a fish entering water, it can quickly blend with common organic solvents such as ethanol and ether, regardless of each other. In water, its solubility is quite limited, just like oil and water, it is difficult to melt, which also makes it show different states in different solvent environments.
Its boiling point and melting point are also one of the characteristics. The boiling point is stable at a certain value under certain conditions. During the heating process, when the temperature gradually rises to the boiling point, it will change from liquid to gaseous like the spirit of sublimation, opening a new journey of form. The melting point is also clear. When the external temperature drops below the melting point, it will solidify from a flowing liquid to a solid state, just like time solidifies, and the form is frozen frame, showing a different kind of static beauty.
These physical and chemical properties, like its unique imprint, make it have different uses and values in many fields, waiting for people to further explore and explore.
Smell it, the smell emitted is relatively mild, not as flamboyant as some pungent substances, but with a faint and faint special smell, just like a fragrance hidden in the depths of the forest.
In terms of solubility, it shows good compatibility in organic solvents, just like a fish entering water, it can quickly blend with common organic solvents such as ethanol and ether, regardless of each other. In water, its solubility is quite limited, just like oil and water, it is difficult to melt, which also makes it show different states in different solvent environments.
Its boiling point and melting point are also one of the characteristics. The boiling point is stable at a certain value under certain conditions. During the heating process, when the temperature gradually rises to the boiling point, it will change from liquid to gaseous like the spirit of sublimation, opening a new journey of form. The melting point is also clear. When the external temperature drops below the melting point, it will solidify from a flowing liquid to a solid state, just like time solidifies, and the form is frozen frame, showing a different kind of static beauty.
These physical and chemical properties, like its unique imprint, make it have different uses and values in many fields, waiting for people to further explore and explore.
What are the common uses of 1- (2-bromoethyl) -4-chlorobenzene?
1- (2-hydroxyethyl) -4-nitrobenzene has many common uses. This compound is often used as a key intermediate in the synthesis of many drugs in the field of medicine. Due to its chemical structure, it can be introduced into drug molecules through a series of chemical reactions, giving the drug specific pharmacological activity. For example, some drugs with antibacterial and anti-inflammatory effects are often synthesized with it as the starting material. By chemically modifying it, the active structure of the drug can be precisely constructed to achieve the purpose of treating diseases.
In the field of materials science, 1- (2-hydroxyethyl) -4-nitrobenzene also has important applications. It can participate in the synthesis of polymer materials. Using it as a monomer or modifier and incorporating it into a polymer system can significantly improve the properties of materials. For example, when preparing high-performance engineering plastics, adding an appropriate amount of this compound can improve the heat resistance, mechanical strength and chemical stability of plastics, making it widely used in aerospace, automobile manufacturing and other fields that require strict material properties.
Furthermore, in the field of organic synthetic chemistry, 1 - (2-hydroxyethyl) - 4 - nitrobenzene is an extremely important synthetic building block. Chemists can flexibly use various organic reactions, such as nucleophilic substitution, reduction, oxidation, and other reactions, to construct complex organic molecular structures, providing an important foundation for the development and synthesis of new organic compounds, and assisting in the continuous development and innovation of organic synthetic chemistry.
In the field of materials science, 1- (2-hydroxyethyl) -4-nitrobenzene also has important applications. It can participate in the synthesis of polymer materials. Using it as a monomer or modifier and incorporating it into a polymer system can significantly improve the properties of materials. For example, when preparing high-performance engineering plastics, adding an appropriate amount of this compound can improve the heat resistance, mechanical strength and chemical stability of plastics, making it widely used in aerospace, automobile manufacturing and other fields that require strict material properties.
Furthermore, in the field of organic synthetic chemistry, 1 - (2-hydroxyethyl) - 4 - nitrobenzene is an extremely important synthetic building block. Chemists can flexibly use various organic reactions, such as nucleophilic substitution, reduction, oxidation, and other reactions, to construct complex organic molecular structures, providing an important foundation for the development and synthesis of new organic compounds, and assisting in the continuous development and innovation of organic synthetic chemistry.
What are the synthesis methods of 1- (2-bromoethyl) -4-chlorobenzene?
To prepare 1- (2-hydroxyethyl) -4-nitrobenzene, there are many ways to synthesize it. The following is a detailed description of Jun.
First, p-nitroacetophenone can be started from p-nitroacetophenone. First, p-nitroacetophenone and formaldehyde are subjected to hydroxyaldehyde condensation in an alkaline environment. Due to the high activity of aldehyde groups, under the action of alkali, the α-hydrogen of p-nitroacetophenone can be added to the carbonyl group of formaldehyde to form a β-hydroxyaldehyde intermediate. This intermediate can be dehydrated to obtain products containing ethylenes. Subsequently, the alkene bond is hydrogenated and reduced, while paying attention to the protection of nitro groups to avoid excessive reduction during the reduction process, and finally 1- (2-hydroxyethyl) -4-nitrobenzene can be obtained.
Second, p-nitrotoluene is used as the raw material. First, halogen atoms are introduced into the side chain of toluene through halogenation reaction. Commonly used halogenating agents such as N-bromosuccinimide (NBS) can selectively introduce bromine atoms at the benzyl position under the action of initiators such as benzoyl peroxide to obtain p-nitrobenzyl bromide. After that, p-nitrobenzyl bromide and ethylene glycol undergo nucleophilic substitution reaction, and the bromine atom is replaced by the hydroxyl group of ethylene glycol to form an ether bond. The obtained product is then oxidized, and another hydrogen atom at the benzyl position is oxidized to a hydroxyl group to obtain the target product.
Third, p-nitrophenol and ethylene oxide are used as starting materials. The phenolic hydroxyl group of p-nitrophenol is nucleophilic, and the ternary ring of ethylene oxide has high tension. Under the catalysis of an appropriate catalyst such as a base, the phenolic hydroxyl group of p-nitrophenol attacks the carbon atom of ethylene oxide, and ring-opening addition forms 1- (2-hydroxyethyl) -4-nitrobenzene. This method is relatively simple and has a high atomic utilization rate. However, attention should be paid to the control of reaction conditions to prevent side reactions such as polymerization of ethylene oxide.
First, p-nitroacetophenone can be started from p-nitroacetophenone. First, p-nitroacetophenone and formaldehyde are subjected to hydroxyaldehyde condensation in an alkaline environment. Due to the high activity of aldehyde groups, under the action of alkali, the α-hydrogen of p-nitroacetophenone can be added to the carbonyl group of formaldehyde to form a β-hydroxyaldehyde intermediate. This intermediate can be dehydrated to obtain products containing ethylenes. Subsequently, the alkene bond is hydrogenated and reduced, while paying attention to the protection of nitro groups to avoid excessive reduction during the reduction process, and finally 1- (2-hydroxyethyl) -4-nitrobenzene can be obtained.
Second, p-nitrotoluene is used as the raw material. First, halogen atoms are introduced into the side chain of toluene through halogenation reaction. Commonly used halogenating agents such as N-bromosuccinimide (NBS) can selectively introduce bromine atoms at the benzyl position under the action of initiators such as benzoyl peroxide to obtain p-nitrobenzyl bromide. After that, p-nitrobenzyl bromide and ethylene glycol undergo nucleophilic substitution reaction, and the bromine atom is replaced by the hydroxyl group of ethylene glycol to form an ether bond. The obtained product is then oxidized, and another hydrogen atom at the benzyl position is oxidized to a hydroxyl group to obtain the target product.
Third, p-nitrophenol and ethylene oxide are used as starting materials. The phenolic hydroxyl group of p-nitrophenol is nucleophilic, and the ternary ring of ethylene oxide has high tension. Under the catalysis of an appropriate catalyst such as a base, the phenolic hydroxyl group of p-nitrophenol attacks the carbon atom of ethylene oxide, and ring-opening addition forms 1- (2-hydroxyethyl) -4-nitrobenzene. This method is relatively simple and has a high atomic utilization rate. However, attention should be paid to the control of reaction conditions to prevent side reactions such as polymerization of ethylene oxide.
What are the precautions for storing and transporting 1- (2-bromoethyl) -4-chlorobenzene?
Cyanoethyl butyronitrile is not suitable for storage and storage, and there is no need to pay more attention to it.
Cyanoethyl, the sexual activity of cyanoethyl, when it is not stored, it must be damaged, dry and good. If it is exposed to high temperatures and high tides, it is feared that its chemical properties will be destroyed, causing the amount to be affected. And it is isolated from oxidizing materials, acids and other substances, in order to prevent the reaction of the strong reaction and endanger safety. The package is also shipped to prevent leakage.
Nitrile should not be ignored. Its storage should be in a room that is clean and well-connected, where there is no fire and no source. Because of its flammability, it can explode in case of open flame or high temperature combustible. The storage quality is also suitable. Generally, the temperature is 5-35 ° C. High or low temperature may affect its performance.
In this case, cyanoethyl butyronitrile should be operated according to the quality of dangerous products. It must be equipped with appropriate fire equipment and emergency management of leaks. During the unloading process, it is necessary to unload, and it is forbidden to drop and collide, so as to avoid the leakage of materials due to package breakage. On the way, the company will pay attention to the materials and avoid densely populated areas and high-speed road sections.
In addition, all the people are well-versed in the characteristics, hazards and emergency management measures of cyanoethyl butyronitrile. In the event of an accident such as leakage, it can be dealt with quickly and properly to minimize harm. In this way, the safety of cyanoethyl butyronitrile can be guaranteed in the storage and storage process.
Cyanoethyl, the sexual activity of cyanoethyl, when it is not stored, it must be damaged, dry and good. If it is exposed to high temperatures and high tides, it is feared that its chemical properties will be destroyed, causing the amount to be affected. And it is isolated from oxidizing materials, acids and other substances, in order to prevent the reaction of the strong reaction and endanger safety. The package is also shipped to prevent leakage.
Nitrile should not be ignored. Its storage should be in a room that is clean and well-connected, where there is no fire and no source. Because of its flammability, it can explode in case of open flame or high temperature combustible. The storage quality is also suitable. Generally, the temperature is 5-35 ° C. High or low temperature may affect its performance.
In this case, cyanoethyl butyronitrile should be operated according to the quality of dangerous products. It must be equipped with appropriate fire equipment and emergency management of leaks. During the unloading process, it is necessary to unload, and it is forbidden to drop and collide, so as to avoid the leakage of materials due to package breakage. On the way, the company will pay attention to the materials and avoid densely populated areas and high-speed road sections.
In addition, all the people are well-versed in the characteristics, hazards and emergency management measures of cyanoethyl butyronitrile. In the event of an accident such as leakage, it can be dealt with quickly and properly to minimize harm. In this way, the safety of cyanoethyl butyronitrile can be guaranteed in the storage and storage process.
What are the effects of 1- (2-bromoethyl) -4-chlorobenzene on the environment and human health?
The effects of 1 - (2 -hydroxyethyl) -4 -chlorobenzene on the environment and human health are quite complex, and it is said in ancient Chinese.
At the environmental end, it is in the water body, or it may cause water quality deterioration. Aquatic organisms depend on water for their survival. If this substance enters the water body, it may disturb its normal physiological functions. Such as the gills of fish, which are for breathing, are invaded by this substance, or cause gas exchange to be blocked, causing fish to lack oxygen, lose vitality, and even die. In the soil, or change the physical and chemical properties of the soil, affecting the community structure and function of soil microorganisms. Microorganisms have a significant role in soil material circulation and nutrient transformation. If microorganisms are suppressed, soil fertility may decline, affecting plant growth.
As for human health, through breathing, skin contact or dietary intake, it can be harmful. Entering the respiratory system, or irritating the mucosa of the respiratory tract, causing cough and asthma, or damaging the function of the lungs for a long time. If it comes into contact with the skin, it can penetrate the skin into the body, or cause skin allergies, such as red rash and itching. Oral ingestion, or damaging the digestive system, causing abdominal pain, diarrhea, and even affecting important organs such as the liver and kidneys. The liver, the detoxification organ of the human body, and the kidneys, the main excretion. This substance may damage the liver and kidneys, causing damage to their function and endangering life and health. Therefore, the harm of 1- (2-hydroxyethyl) -4-chlorobenzene to the environment and human health should not be underestimated, and it should be handled with caution to prevent its spread and ensure the safety of the environment and human health.
At the environmental end, it is in the water body, or it may cause water quality deterioration. Aquatic organisms depend on water for their survival. If this substance enters the water body, it may disturb its normal physiological functions. Such as the gills of fish, which are for breathing, are invaded by this substance, or cause gas exchange to be blocked, causing fish to lack oxygen, lose vitality, and even die. In the soil, or change the physical and chemical properties of the soil, affecting the community structure and function of soil microorganisms. Microorganisms have a significant role in soil material circulation and nutrient transformation. If microorganisms are suppressed, soil fertility may decline, affecting plant growth.
As for human health, through breathing, skin contact or dietary intake, it can be harmful. Entering the respiratory system, or irritating the mucosa of the respiratory tract, causing cough and asthma, or damaging the function of the lungs for a long time. If it comes into contact with the skin, it can penetrate the skin into the body, or cause skin allergies, such as red rash and itching. Oral ingestion, or damaging the digestive system, causing abdominal pain, diarrhea, and even affecting important organs such as the liver and kidneys. The liver, the detoxification organ of the human body, and the kidneys, the main excretion. This substance may damage the liver and kidneys, causing damage to their function and endangering life and health. Therefore, the harm of 1- (2-hydroxyethyl) -4-chlorobenzene to the environment and human health should not be underestimated, and it should be handled with caution to prevent its spread and ensure the safety of the environment and human health.
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