Linshang Chemical
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1-(2-Chloroethyl)Benzene
Linshang Chemical
|
HS Code |
948042 |
| Chemical Formula | C8H9Cl |
| Molar Mass | 140.61 g/mol |
| Appearance | Colorless to light - yellow liquid |
| Odor | Characteristic aromatic odor |
| Boiling Point | 197 - 199 °C |
| Melting Point | −35 °C |
| Density | 1.069 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Flash Point | 73 °C |
| Vapor Pressure | 0.133 kPa (20 °C) |
As an accredited 1-(2-Chloroethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 mL of 1-(2 - chloroethyl)benzene in a tightly - sealed glass bottle. |
| Storage | 1-(2 - chloroethyl)benzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. It should be kept in a tightly - sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents and reactive substances to prevent potential chemical reactions. Ensure proper labeling for easy identification. |
| Shipping | 1-(2 - chloroethyl)benzene is shipped in tightly sealed, corrosion - resistant containers. It must be transported in accordance with hazardous chemical regulations, ensuring proper labeling, and avoiding exposure to heat, ignition sources, and incompatible substances. |
Competitive 1-(2-Chloroethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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What are the main uses of 1- (2 - chloroethyl) benzene?
1 - (2 - chloroethyl) benzene, this is an organic compound. It has a wide range of uses. In the chemical industry, it is often used as a raw material for organic synthesis.
In the drug synthesis path, it can be used as a key intermediate. The structural properties of the phenyl ring and chloroethyl group can be introduced through a series of chemical reactions, such as nucleophilic substitution, redox, etc., to introduce other functional groups to construct molecular structures with specific pharmacological activities.
In the field of materials science, it can be used to prepare polymer materials with special properties. By polymerizing with other monomers, its structural units are integrated into the polymer chain, giving the material unique properties such as good solubility and thermal stability.
In addition, in the preparation of fine chemical products, it also has important uses. Like the synthesis of special fragrances, additives, etc., can add special efficacy or performance to the product by virtue of its unique chemical structure.
Therefore, 1- (2-chloroethyl) benzene plays an indispensable role in the synthesis path of many chemical and related industries due to its own chemical structure, and is of great significance to promote the development of various fields.
In the drug synthesis path, it can be used as a key intermediate. The structural properties of the phenyl ring and chloroethyl group can be introduced through a series of chemical reactions, such as nucleophilic substitution, redox, etc., to introduce other functional groups to construct molecular structures with specific pharmacological activities.
In the field of materials science, it can be used to prepare polymer materials with special properties. By polymerizing with other monomers, its structural units are integrated into the polymer chain, giving the material unique properties such as good solubility and thermal stability.
In addition, in the preparation of fine chemical products, it also has important uses. Like the synthesis of special fragrances, additives, etc., can add special efficacy or performance to the product by virtue of its unique chemical structure.
Therefore, 1- (2-chloroethyl) benzene plays an indispensable role in the synthesis path of many chemical and related industries due to its own chemical structure, and is of great significance to promote the development of various fields.
What are the physical properties of 1- (2 - chloroethyl) benzene
1 - (2 - chloroethyl) benzene is one of the organic compounds. Its physical properties are quite important and are related to many practical applications.
First of all, its appearance, under room temperature and pressure, 1 - (2 - chloroethyl) benzene is usually colorless to light yellow liquid. The view is clear. If it is clear water, it has a special smell, and its chemical characteristics can be known by smelling.
When it comes to boiling point, it is between 185 and 187 degrees Celsius. The boiling point is the critical temperature at which a substance changes from liquid to gas. This temperature range indicates that in order to boil and vaporize it, the corresponding heat needs to be provided. In industrial production or experimental operations, separation and purification methods such as distillation can be carried out.
Furthermore, its melting point is relatively low, about -70 degrees Celsius. The melting point is the temperature limit at which a substance changes from a solid state to a liquid state. The lower melting point makes it difficult for 1 - (2 - chloroethyl) benzene to be in a solid state at room temperature, and it is mostly a flowing liquid, which is convenient for storage and transportation.
The density of 1 - (2 - chloroethyl) benzene is about 1.07 to 1.08 g/cm3. The density is also the mass per unit volume of the substance. This value shows that its density is slightly higher than that of water. If mixed with water, it will sink underwater.
In terms of solubility, 1- (2-chloroethyl) benzene is insoluble in water, but soluble in a variety of organic solvents, such as ethanol, ether, acetone, etc. This property is particularly critical in the field of organic synthesis, and can be used as a solvent or a medium to participate in the reaction, so that various organic reactions can proceed smoothly.
In addition, 1- (2-chloroethyl) benzene is flammable and is highly flammable in case of open flames and hot topics. When storing and using, special attention must be paid to fire and explosion prevention, and strict safety regulations must be followed to avoid dangerous accidents such as fires.
First of all, its appearance, under room temperature and pressure, 1 - (2 - chloroethyl) benzene is usually colorless to light yellow liquid. The view is clear. If it is clear water, it has a special smell, and its chemical characteristics can be known by smelling.
When it comes to boiling point, it is between 185 and 187 degrees Celsius. The boiling point is the critical temperature at which a substance changes from liquid to gas. This temperature range indicates that in order to boil and vaporize it, the corresponding heat needs to be provided. In industrial production or experimental operations, separation and purification methods such as distillation can be carried out.
Furthermore, its melting point is relatively low, about -70 degrees Celsius. The melting point is the temperature limit at which a substance changes from a solid state to a liquid state. The lower melting point makes it difficult for 1 - (2 - chloroethyl) benzene to be in a solid state at room temperature, and it is mostly a flowing liquid, which is convenient for storage and transportation.
The density of 1 - (2 - chloroethyl) benzene is about 1.07 to 1.08 g/cm3. The density is also the mass per unit volume of the substance. This value shows that its density is slightly higher than that of water. If mixed with water, it will sink underwater.
In terms of solubility, 1- (2-chloroethyl) benzene is insoluble in water, but soluble in a variety of organic solvents, such as ethanol, ether, acetone, etc. This property is particularly critical in the field of organic synthesis, and can be used as a solvent or a medium to participate in the reaction, so that various organic reactions can proceed smoothly.
In addition, 1- (2-chloroethyl) benzene is flammable and is highly flammable in case of open flames and hot topics. When storing and using, special attention must be paid to fire and explosion prevention, and strict safety regulations must be followed to avoid dangerous accidents such as fires.
Is 1- (2 - chloroethyl) benzene chemically stable?
1 - (2 - chloroethyl) benzene, its chemical properties are still stable at room temperature and pressure. In this compound, the benzene ring is a stable conjugated system, giving it a certain degree of chemical inertness. However, the (2 - chloroethyl) part of the side chain gives the substance a unique reactivity.
Chlorine atoms can cause electron clouds to shift on the side chain due to their high electronegativity, making the carbon atoms connected to them partially positive, which makes the carbon atoms vulnerable to attack by nucleophiles. When encountering nucleophiles, chlorine atoms can be replaced, resulting in a variety of new compounds.
Because of its benzene-containing ring structure, typical reactions of aromatic hydrocarbons, such as electrophilic substitution reactions, can occur. Under suitable conditions, the hydrogen atom on the benzene ring can be replaced by other groups, such as halogenation, nitrification, and sulfonation.
However, if the environmental conditions do not have corresponding initiators, such as no specific catalyst, suitable temperature and pressure, etc., 1 - (2 - chloroethyl) benzene can usually maintain the stability of its own structure and is not prone to spontaneous chemical reactions. Overall, the stability of 1 - (2 - chloroethyl) benzene is a relative concept, and the development of its chemical properties depends on external conditions.
Chlorine atoms can cause electron clouds to shift on the side chain due to their high electronegativity, making the carbon atoms connected to them partially positive, which makes the carbon atoms vulnerable to attack by nucleophiles. When encountering nucleophiles, chlorine atoms can be replaced, resulting in a variety of new compounds.
Because of its benzene-containing ring structure, typical reactions of aromatic hydrocarbons, such as electrophilic substitution reactions, can occur. Under suitable conditions, the hydrogen atom on the benzene ring can be replaced by other groups, such as halogenation, nitrification, and sulfonation.
However, if the environmental conditions do not have corresponding initiators, such as no specific catalyst, suitable temperature and pressure, etc., 1 - (2 - chloroethyl) benzene can usually maintain the stability of its own structure and is not prone to spontaneous chemical reactions. Overall, the stability of 1 - (2 - chloroethyl) benzene is a relative concept, and the development of its chemical properties depends on external conditions.
What are the preparation methods of 1- (2 - chloroethyl) benzene
The method of making 1 - (2 - chloroethyl) benzene has been explored by many scholars in the past, and the following numbers are briefly described.
First, benzene and 2 - chloroethanol can be reacted with the help of suitable catalysts. Commonly used catalysts, such as protonic acids, sulfuric acid can be one of them. During the reaction, sulfuric acid prompts an electrophilic substitution reaction between benzene and 2 - chloroethanol. The hydroxyl group of 2 - chloroethyl ethanol is converted into an easy-to-leave group by the action of sulfuric acid, and the electron cloud density of the benzene ring is high, which produces an electrophilic attack on it, and then generates 1 - (2 - chloroethyl) benzene. However, this process needs to pay attention to the reaction temperature and the amount of sulfuric acid. If the temperature is too high, it is easy to produce side reactions. Excessive sulfuric acid will also cause corrosion to the equipment, and subsequent separation also needs to be handled with caution.
Second, benzene and ethylene oxide can be used as the starting material to react in the presence of a specific Lewis acid catalyst. Such as aluminum trichloride, this is a common Lewis acid. Ethylene oxide opens the ring under the action of aluminum trichloride to form an active intermediate, and the benzene ring attacks it immediately, and the target product is obtained through a series of changes. The advantage of this method is that the raw material is relatively easy to obtain, but aluminum trichloride requires strict reaction conditions, and it is easy to hydrolyze and fail in contact with water. Moreover, the post-reaction treatment process is complicated, and the aluminum
Third, the addition reaction is carried out with styrene and hydrogen chloride gas as raw materials. Under the catalysis of suitable addition catalysts, such as some transition metal complexes, the carbon-carbon double bond of styrene and hydrogen chloride are added. Following the Markov rule, hydrogen atoms are added to the double-bonded carbon atoms with more hydrogen, and chlorine atoms are added to another double-bonded carbon atom to generate 1 - (2 - chloroethyl) benzene. This route is relatively simple to operate and has high atomic utilization. However, attention should be paid to the safe use of hydrogen chloride gas. Due to its corrosive and irritating properties, the reaction equipment needs to be well sealed and protected.
First, benzene and 2 - chloroethanol can be reacted with the help of suitable catalysts. Commonly used catalysts, such as protonic acids, sulfuric acid can be one of them. During the reaction, sulfuric acid prompts an electrophilic substitution reaction between benzene and 2 - chloroethanol. The hydroxyl group of 2 - chloroethyl ethanol is converted into an easy-to-leave group by the action of sulfuric acid, and the electron cloud density of the benzene ring is high, which produces an electrophilic attack on it, and then generates 1 - (2 - chloroethyl) benzene. However, this process needs to pay attention to the reaction temperature and the amount of sulfuric acid. If the temperature is too high, it is easy to produce side reactions. Excessive sulfuric acid will also cause corrosion to the equipment, and subsequent separation also needs to be handled with caution.
Second, benzene and ethylene oxide can be used as the starting material to react in the presence of a specific Lewis acid catalyst. Such as aluminum trichloride, this is a common Lewis acid. Ethylene oxide opens the ring under the action of aluminum trichloride to form an active intermediate, and the benzene ring attacks it immediately, and the target product is obtained through a series of changes. The advantage of this method is that the raw material is relatively easy to obtain, but aluminum trichloride requires strict reaction conditions, and it is easy to hydrolyze and fail in contact with water. Moreover, the post-reaction treatment process is complicated, and the aluminum
Third, the addition reaction is carried out with styrene and hydrogen chloride gas as raw materials. Under the catalysis of suitable addition catalysts, such as some transition metal complexes, the carbon-carbon double bond of styrene and hydrogen chloride are added. Following the Markov rule, hydrogen atoms are added to the double-bonded carbon atoms with more hydrogen, and chlorine atoms are added to another double-bonded carbon atom to generate 1 - (2 - chloroethyl) benzene. This route is relatively simple to operate and has high atomic utilization. However, attention should be paid to the safe use of hydrogen chloride gas. Due to its corrosive and irritating properties, the reaction equipment needs to be well sealed and protected.
What are the precautions for 1- (2 - chloroethyl) benzene in storage and transportation?
For 1 - (2 - chloroethyl) benzene, pay attention to many matters when storing and transporting. This substance is volatile and irritating to a certain extent, so when storing, it should be placed in a cool and well-ventilated place, away from fire and heat sources, to prevent the risk of fire or explosion. It should be stored separately from oxidants, acids, alkalis, etc., and must not be mixed. The lid is active because of its chemical properties. If it encounters them, it may cause chemical reactions and cause danger.
Furthermore, the storage container must be tightly sealed to prevent leakage. If there is a leakage, proper emergency measures should be taken immediately. When transporting, the relevant regulations must also be strictly followed. Transportation vehicles shall be equipped with the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment. During transportation, it should be protected from exposure to the sun, rain, and high temperature. When loading and unloading, it should be handled lightly to prevent damage to packaging and containers.
Escort personnel should also be familiar with the characteristics of this substance and emergency treatment methods. Pay close attention during transportation. Once any abnormalities are found, they should be disposed of immediately according to the established plan. In this way, it is necessary to ensure that 1- (2-chloroethyl) benzene is safe during storage and transportation.
Furthermore, the storage container must be tightly sealed to prevent leakage. If there is a leakage, proper emergency measures should be taken immediately. When transporting, the relevant regulations must also be strictly followed. Transportation vehicles shall be equipped with the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment. During transportation, it should be protected from exposure to the sun, rain, and high temperature. When loading and unloading, it should be handled lightly to prevent damage to packaging and containers.
Escort personnel should also be familiar with the characteristics of this substance and emergency treatment methods. Pay close attention during transportation. Once any abnormalities are found, they should be disposed of immediately according to the established plan. In this way, it is necessary to ensure that 1- (2-chloroethyl) benzene is safe during storage and transportation.
What are the main uses of 1- (2-chloroethyl) benzene?
1 - (2 - chloroethyl) benzene has many main uses. In the field of organic synthesis, this is the key raw material. If you want to make an organic compound with a specific structure, it is often relied on as the starting material. With its active chlorine atom, it can interact with many nucleophiles by substitution reaction, and then introduce other functional groups, paving the way for the construction of complex organic molecules.
In the field of materials science, it also has extraordinary functions. Or it can contribute to the preparation of special polymer materials. Through appropriate polymerization reactions, its structural units are integrated into the polymer backbone, so that the material obtains unique properties, such as improving the solubility and thermal stability of the material, or endowing it with specific optical and electrical properties.
Furthermore, it also has potential value in the field of medicinal chemistry. Some bioactive compounds may require 1- (2-chloroethyl) benzene as the basic structure for their synthesis. After chemical modification and derivatization, new drug molecules may be created, opening up new avenues for pharmaceutical research and development.
In addition, it is often found in the preparation of fine chemical products. It can be used to synthesize special fragrances, dyes and other fine chemicals. With its unique chemical structure, it imparts specific properties and application properties to the product. In conclusion, 1 - (2 - chloroethyl) benzene plays an indispensable role in many fields such as organic synthesis, materials science, medicinal chemistry, and fine chemistry, and is an important cornerstone of many industrial production and scientific research.
In the field of materials science, it also has extraordinary functions. Or it can contribute to the preparation of special polymer materials. Through appropriate polymerization reactions, its structural units are integrated into the polymer backbone, so that the material obtains unique properties, such as improving the solubility and thermal stability of the material, or endowing it with specific optical and electrical properties.
Furthermore, it also has potential value in the field of medicinal chemistry. Some bioactive compounds may require 1- (2-chloroethyl) benzene as the basic structure for their synthesis. After chemical modification and derivatization, new drug molecules may be created, opening up new avenues for pharmaceutical research and development.
In addition, it is often found in the preparation of fine chemical products. It can be used to synthesize special fragrances, dyes and other fine chemicals. With its unique chemical structure, it imparts specific properties and application properties to the product. In conclusion, 1 - (2 - chloroethyl) benzene plays an indispensable role in many fields such as organic synthesis, materials science, medicinal chemistry, and fine chemistry, and is an important cornerstone of many industrial production and scientific research.
What are the physical properties of 1- (2-chloroethyl) benzene
1 - (2 -chloroethyl) benzene is one of the organic compounds. Its physical properties are quite impressive, and let me tell them one by one.
Looking at its appearance, it is often a colorless to light yellow liquid, clear and translucent, like the first condensation of morning dew, clear and clear. Smell it, it has a special aromatic smell, although it is not as rich as the orchid, it also has its unique charm. However, this smell should not be smelled for a long time to prevent damage to the body.
In terms of its solubility, this substance is slightly soluble in water, just like oil floats in water, and the two are difficult to blend. However, in organic solvents, such as alcohols, ethers, benzene, etc., it can be easily dissolved, just like a fish entering water, and it is free. This property stems from the similarity of its molecular structure to that of organic solvents.
As for the melting point and boiling point, the melting point is quite low, and it is difficult to condense into a solid state at room temperature, and it mostly exists in a liquid state. The boiling point varies according to specific conditions. Generally speaking, it is within a certain temperature range. When the external environment reaches the corresponding boiling point, it will change from a liquid state to a gas state, just like a feather flying and changing shape.
In terms of density, 1 - (2 - chloroethyl) benzene is slightly heavier than water, so if it is mixed with water, it will sink underwater, just like a stone falling to the bottom of the abyss, which is clearly identifiable.
In addition, its vapor pressure is also an important physical property. At a certain temperature, when the substance is in a closed container, some molecules will escape the liquid surface and form steam, and the pressure generated by the steam is the vapor pressure. The magnitude of this pressure is closely related to the temperature. The higher the temperature, the greater the vapor pressure, just like the more intense the fire, the more intense the hot gas.
The above physical properties are of great significance in many fields such as chemical engineering and scientific research, and are relevant to many matters such as their application, storage and transportation.
Looking at its appearance, it is often a colorless to light yellow liquid, clear and translucent, like the first condensation of morning dew, clear and clear. Smell it, it has a special aromatic smell, although it is not as rich as the orchid, it also has its unique charm. However, this smell should not be smelled for a long time to prevent damage to the body.
In terms of its solubility, this substance is slightly soluble in water, just like oil floats in water, and the two are difficult to blend. However, in organic solvents, such as alcohols, ethers, benzene, etc., it can be easily dissolved, just like a fish entering water, and it is free. This property stems from the similarity of its molecular structure to that of organic solvents.
As for the melting point and boiling point, the melting point is quite low, and it is difficult to condense into a solid state at room temperature, and it mostly exists in a liquid state. The boiling point varies according to specific conditions. Generally speaking, it is within a certain temperature range. When the external environment reaches the corresponding boiling point, it will change from a liquid state to a gas state, just like a feather flying and changing shape.
In terms of density, 1 - (2 - chloroethyl) benzene is slightly heavier than water, so if it is mixed with water, it will sink underwater, just like a stone falling to the bottom of the abyss, which is clearly identifiable.
In addition, its vapor pressure is also an important physical property. At a certain temperature, when the substance is in a closed container, some molecules will escape the liquid surface and form steam, and the pressure generated by the steam is the vapor pressure. The magnitude of this pressure is closely related to the temperature. The higher the temperature, the greater the vapor pressure, just like the more intense the fire, the more intense the hot gas.
The above physical properties are of great significance in many fields such as chemical engineering and scientific research, and are relevant to many matters such as their application, storage and transportation.
What are the chemical properties of 1- (2-chloroethyl) benzene?
1 - (2 - chloroethyl) benzene is one of the organic compounds. In its molecular structure, one of the benzene rings is connected with a (2 - chloroethyl) group. On its chemical properties, its substitution reaction is discussed first. Because the chlorine atom is quite active, under suitable conditions, the chlorine atom on (2 - chloroethyl) is easily replaced by a nucleophilic reagent. If an aqueous solution of sodium hydroxide is used as the reaction medium, the chlorine atom can be replaced by a hydroxyl group during the heating process, thereby generating 1 - (2 - hydroxyethyl) benzene. The mechanism of this reaction is that the hydroxyl negative ion acts as a nucleophilic reagent to attack the carbon atom connected to the chlorine atom, and the chlorine atom leaves with a pair of electrons. This is a typical nucleophilic substitution reaction path.
Furthermore, 1- (2-chloroethyl) benzene can also undergo a elimination reaction. When an alcohol solution of potassium hydroxide is used as the reaction condition and properly heated, the (2-chloroethyl) part will remove the hydrogen chloride molecule, forming a double bond between the benzene ring and the ethylene group to form styrene. In this process, the base captures the hydrogen atom on the adjacent carbon atom of the chlorine atom, and the chlorine atom leaves with electrons, which is achieved through the E1 or E2 elimination reaction mechanism.
In terms of the nature of its benzene ring part, because the benzene ring has a conjugated system, 1- (2-chloroethyl) benzene can undergo electrophilic substitution reactions on the benzene ring. For example, under the catalysis of ferric chloride, it can react with bromine, and the bromine atom replaces the hydrogen atom on the benzene ring, mainly forming ortho or para-substitution products. This is because the electron cloud density of the benzene ring is higher, which is easy to attract electrophilic reagents, and (2-chloroethyl) is an activating group. Although the chlorine atom has a certain electron-absorbing induction effect, (2-chloroethyl) as a whole increases the electron cloud density of the benzene ring, and the electron cloud density of the ortho and para-position increases more significantly, so the electrophilic substitution reaction easily occurs in the ortho and para-position.
In addition, in 1- (2-chloroethyl) benzene, there is an interaction between the benzene ring and (2-chloroethyl). The conjugated system of benzene ring can change the electron cloud distribution of (2-chloroethyl), which affects the activity of chlorine atoms; conversely, (2-chloroethyl) also affects the electron cloud density and reactivity of benzene ring. Overall, 1 - (2-chloroethyl) benzene has rich chemical properties and has important application value in organic synthesis and other fields.
Furthermore, 1- (2-chloroethyl) benzene can also undergo a elimination reaction. When an alcohol solution of potassium hydroxide is used as the reaction condition and properly heated, the (2-chloroethyl) part will remove the hydrogen chloride molecule, forming a double bond between the benzene ring and the ethylene group to form styrene. In this process, the base captures the hydrogen atom on the adjacent carbon atom of the chlorine atom, and the chlorine atom leaves with electrons, which is achieved through the E1 or E2 elimination reaction mechanism.
In terms of the nature of its benzene ring part, because the benzene ring has a conjugated system, 1- (2-chloroethyl) benzene can undergo electrophilic substitution reactions on the benzene ring. For example, under the catalysis of ferric chloride, it can react with bromine, and the bromine atom replaces the hydrogen atom on the benzene ring, mainly forming ortho or para-substitution products. This is because the electron cloud density of the benzene ring is higher, which is easy to attract electrophilic reagents, and (2-chloroethyl) is an activating group. Although the chlorine atom has a certain electron-absorbing induction effect, (2-chloroethyl) as a whole increases the electron cloud density of the benzene ring, and the electron cloud density of the ortho and para-position increases more significantly, so the electrophilic substitution reaction easily occurs in the ortho and para-position.
In addition, in 1- (2-chloroethyl) benzene, there is an interaction between the benzene ring and (2-chloroethyl). The conjugated system of benzene ring can change the electron cloud distribution of (2-chloroethyl), which affects the activity of chlorine atoms; conversely, (2-chloroethyl) also affects the electron cloud density and reactivity of benzene ring. Overall, 1 - (2-chloroethyl) benzene has rich chemical properties and has important application value in organic synthesis and other fields.
What are the synthesis methods of 1- (2-chloroethyl) benzene
To prepare 1 - (2 - chloroethyl) benzene, there are two methods. First, start with styrene and add hydrogen chloride. The double bond of styrene reacts with hydrogen chloride, and hydrogen and chlorine each attach to the carbon at both ends of the double bond, resulting in 1 - (2 - chloroethyl) benzene. This reaction is mild, easy to handle, and the yield can be observed.
Second, benzene and 1,2 - dichloroethane are used as materials, and Lewis acid such as aluminum trichloride is used as a catalyst to carry out the Fu-gram alkylation reaction. Under the action of aluminum trichloride, 1,2-dichloroethane generates a positive carbon ion. This ion interacts with the benzene ring to replace the hydrogen on the benzene ring to form 1- (2-chloroethyl) benzene. However, this reaction needs to pay attention to the control conditions, because dichloroethane may have the risk of multiple substitutions, which affects the purity of the product, and aluminum trichloride is corrosive. When operating, be cautious.
In short, both have advantages and disadvantages. In actual preparation, when depending on the specific conditions, such as the availability of raw materials, the conditions of equipment, and the purity of the product, etc., choose the appropriate method.
Second, benzene and 1,2 - dichloroethane are used as materials, and Lewis acid such as aluminum trichloride is used as a catalyst to carry out the Fu-gram alkylation reaction. Under the action of aluminum trichloride, 1,2-dichloroethane generates a positive carbon ion. This ion interacts with the benzene ring to replace the hydrogen on the benzene ring to form 1- (2-chloroethyl) benzene. However, this reaction needs to pay attention to the control conditions, because dichloroethane may have the risk of multiple substitutions, which affects the purity of the product, and aluminum trichloride is corrosive. When operating, be cautious.
In short, both have advantages and disadvantages. In actual preparation, when depending on the specific conditions, such as the availability of raw materials, the conditions of equipment, and the purity of the product, etc., choose the appropriate method.
What are the precautions for 1- (2-chloroethyl) benzene during use?
For 1 - (2 - chloroethyl) benzene, many things need to be paid attention to when using it.
First, it is related to safety protection. This substance is toxic and irritating to a certain extent, and it is necessary to wear appropriate protective equipment when operating. Protective gloves are essential to avoid contact with the skin, causing skin damage or allergies. Protective glasses are also indispensable to protect the eyes from harm. If accidentally splashed into the eyes, serious eye injuries may be caused. In addition, respiratory protection should not be ignored. In areas with poor ventilation, appropriate masks or breathing apparatus should be worn to prevent inhalation of harmful gases and damage to the respiratory tract.
Second, pay attention to storage conditions. It should be stored in a cool, dry and well-ventilated place. Avoid heat and fire, because of its flammability, it is easy to cause combustion and explosion in case of open flames and hot topics. And it needs to be stored separately from oxidants, acids, etc. to prevent dangerous chemical reactions.
Third, pay attention to the operation specifications. The operation process should be rigorous and meticulous to avoid spills. If there is a spill, proper measures should be taken immediately. A small amount of spill can be absorbed by inert materials such as sand and vermiculite; if there is a large amount of spill, it needs to build a dike or dig a pit for containment, and transfer it to a special collector with a pump for recycling or harmless treatment.
Fourth, pay attention to environmental impact. Waste after use should not be discarded at will, and should be properly disposed of in accordance with relevant environmental regulations to prevent environmental pollution.
In short, when using 1- (2-chloroethyl) benzene, the above precautions should be kept in mind and handled with caution to ensure safety.
First, it is related to safety protection. This substance is toxic and irritating to a certain extent, and it is necessary to wear appropriate protective equipment when operating. Protective gloves are essential to avoid contact with the skin, causing skin damage or allergies. Protective glasses are also indispensable to protect the eyes from harm. If accidentally splashed into the eyes, serious eye injuries may be caused. In addition, respiratory protection should not be ignored. In areas with poor ventilation, appropriate masks or breathing apparatus should be worn to prevent inhalation of harmful gases and damage to the respiratory tract.
Second, pay attention to storage conditions. It should be stored in a cool, dry and well-ventilated place. Avoid heat and fire, because of its flammability, it is easy to cause combustion and explosion in case of open flames and hot topics. And it needs to be stored separately from oxidants, acids, etc. to prevent dangerous chemical reactions.
Third, pay attention to the operation specifications. The operation process should be rigorous and meticulous to avoid spills. If there is a spill, proper measures should be taken immediately. A small amount of spill can be absorbed by inert materials such as sand and vermiculite; if there is a large amount of spill, it needs to build a dike or dig a pit for containment, and transfer it to a special collector with a pump for recycling or harmless treatment.
Fourth, pay attention to environmental impact. Waste after use should not be discarded at will, and should be properly disposed of in accordance with relevant environmental regulations to prevent environmental pollution.
In short, when using 1- (2-chloroethyl) benzene, the above precautions should be kept in mind and handled with caution to ensure safety.
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