1,2-Diamino-4-Chlorobenzene
Linshang Chemical
HS Code |
575372 |
Chemical Formula | C6H7ClN2 |
Molar Mass | 142.59 g/mol |
Appearance | Pale yellow to brown solid |
Odor | Characteristic amine - like odor |
Solubility In Water | Slightly soluble |
Melting Point | 63 - 66 °C |
Boiling Point | 285 - 287 °C |
Density | 1.32 g/cm³ |
Flash Point | 153 °C |
Stability | Stable under normal conditions, but may react with strong oxidizing agents |
As an accredited 1,2-Diamino-4-Chlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 1,2 - diamino - 4 - chlorobenzene in 1 - kg bags for secure and convenient storage. |
Storage | 1,2 - Diamino - 4 - chlorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container to prevent moisture absorption and contact with air. Avoid storing near incompatible substances to prevent potential chemical reactions. Label the storage container clearly for easy identification and safety. |
Shipping | 1,2 - Diamino - 4 - chlorobenzene is a chemical. Shipping should follow strict regulations. It must be properly packaged to prevent leakage, transported in vehicles suitable for hazardous chemicals, and accompanied by relevant safety documentation. |
Competitive 1,2-Diamino-4-Chlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 1,2-Diamino-4-Chlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
First, it is an important intermediate in the field of pharmaceutical synthesis. For example, the preparation of some drugs with antibacterial and anti-inflammatory effects often relies on this as the starting material. After a series of chemical reactions, specific functional groups are introduced to shape the specific structure of drug molecules to achieve the required pharmacological activity.
Second, it also has extraordinary performance in the field of materials science. It can be used to prepare special polymer materials, and its special chemical structure can endow the materials with unique properties such as anti-oxidation and light response. In electronic materials, it can optimize the electrical properties of materials and make the performance of electronic products better.
Third, in organic synthetic chemistry, it is a key synthetic building block. Chemists can use the reactivity of two hydroxyl groups and bromine atoms to construct complex organic molecular structures, expand the types and functions of organic compounds, and promote the progress of organic synthetic chemistry.
Fourth, in analytical chemistry, it can be used as a chemical reagent. With its selective reaction with specific substances, it can achieve qualitative and quantitative analysis of certain substances, helping researchers to accurately understand the composition and content of substances.
Its solubility also has characteristics, slightly soluble in water, but soluble in organic solvents such as ethanol and ether. The low solubility in water is due to the fact that although the molecular structure contains hydroxyl groups that can form hydrogen bonds with water, the bromine atom and benzene ring structure limit its affinity with water, so it is difficult to dissolve. In ethanol and ether, the force between it and the organic solvent molecules is appropriate to promote dissolution.
From the perspective of stability, it is relatively stable at room temperature and pressure. However, because it contains active hydroxyl groups and bromine atoms, in case of strong oxidants, the hydroxyl groups are easily oxidized, and the bromine atoms may also undergo reactions such as substitution; in case of high temperature, the molecular structure may be rearranged or decomposed. And it is more sensitive to light, which may trigger photochemical reactions of bromine atoms under light, resulting in changes in its structure and properties.
1,2-dihydroxy-4-bromobenzene is toxic to a certain extent, and contact may irritate the skin, eyes and respiratory tract. Protective measures should be taken during use to avoid direct contact and inhalation to ensure personnel safety and environmental friendliness.
From the perspective of its hydroxyl group, although it has certain activity, it can participate in reactions such as esterification, but under normal circumstances, without specific reaction conditions, such as suitable catalysts, temperatures and reactant concentrations, the reaction is not easy to proceed spontaneously. This is because the electron cloud distribution around the hydroxyl group is affected by the conjugation effect of the benzene ring, and the electron cloud density changes, so that the activity of the hydroxyl group is lower than that of the simple alcohol hydroxyl group.
As for the bromine atom, although it is a halogen atom, the typical reaction of halogenated hydrocarbons is a nucleophilic substitution and elimination reaction. However, in this compound, the bromine atom is attached to the benzene ring, and the conjugate system of the benzene ring enhances the C-Br bond energy of the bromine atom, which inhibits the activity of the bromine atom. To make the bromine atom substitution or elimination reaction, more severe conditions are required, such as strong nucleophilic reagents, high temperatures, etc.
Furthermore, the overall structure of the compound maintains a certain degree of stability due to the conjugate stability of the benzene ring. The conjugate system can disperse electrons, reduce the energy of the molecule, and make the molecule more stable. Therefore, under the environment of conventional temperature, humidity and the presence of general chemical reagents, the chemical properties of 1% 2C2-dihydroxy-4-bromobenzene are quite stable, and significant chemical changes do not occur easily.
One method can be derived from other aromatic hydrocarbons. First, take a suitable aromatic hydrocarbon substrate, and after halogenation, make the chlorine atom attached to a specific position in the benzene ring to obtain chlorine-containing aromatic hydrocarbons. Then, introduce hydroxyl groups by exquisite means. The key here is to precisely control the check point and degree when halogenating, and the subsequent method of introducing hydroxyl groups must be gentle and efficient to prevent side reactions from clumping and destroying the purity of the product.
The second method can be started by phenols. Phenol has its own hydroxyl group, but if you want to obtain the second target, hydroxyl-chlorobenzene, you need to follow a clever path. First protect the phenol ring to prevent it from changing unnecessarily in the subsequent reaction. After chlorination, the chlorine atom is embedded in the benzene ring. Finally, remove the protective group to obtain a pure 1% 2C2-dihydroxy-4-chlorobenzene. The essence of this method lies in the selection and removal of the protective group, and the conditions of the chlorination reaction are all about success or failure.
The third method, or start from a specific benzene derivative. First, the derivative is gradually modified according to specific steps, and through multi-step reactions, the structure of the target molecule is gradually constructed. Each step of the reaction requires careful operation and attention to changes in reaction conditions, such as temperature, solvent, and catalyst. In this way, 1% 2C2-dihydroxy-4-chlorobenzene can be obtained step by step.
This number method has its own strengths and weaknesses. When actually preparing, it is necessary to weigh and choose according to various factors such as the ease of availability of raw materials, the level of cost, the advantages and disadvantages of yield, and the purity and heterogeneity of products, in order to achieve the best preparation.
The first thing to pay attention to is its toxicity. This substance may have certain toxicity and can cause damage to the human body. If inadvertently exposed, whether through skin contact, inhalation or accidental ingestion, it may cause adverse consequences. Skin contact or cause skin irritation, redness, swelling, itching and other symptoms; inhalation of its dust or volatile gaseous substances, or involving the respiratory tract, causing cough, asthma, breathing difficulties, etc.; ingestion may cause serious damage to the digestive system, such as nausea, vomiting, abdominal pain, etc. Therefore, when using, be sure to take protective measures, such as wearing suitable protective gloves, masks, goggles, etc., to prevent contact.
The second is storage. It should be stored in a cool, dry and well-ventilated place. Keep away from fire and heat sources. Due to high temperature or chemical reactions caused by it, the stability will change and may even be dangerous. At the same time, it should be stored separately from oxidants, acids, alkalis, etc., to avoid mixed storage to prevent chemical reactions and accidents.
Furthermore, the use environment should also be paid attention to. The operation should be carried out in the fume hood to ensure that the volatile gas can be discharged in time, reduce the concentration of the substance in the air, and reduce the harm to the operator. If used in a poorly ventilated environment, gas accumulation will not only endanger health, but also increase the risk of explosion.
Repeat, the use process must strictly follow the operating procedures. Precise weighing, according to the amount required for experiment or production, to avoid waste, while preventing problems caused by improper dosage. After use, properly dispose of the remaining substances and waste, and do not discard them at will to prevent environmental pollution.
In short, during the use of 1% 2C2-dihydroxy-4-chlorobenzene, toxicity prevention, proper storage, suitable environment and standardized operation are all key considerations, and must not be neglected to ensure the safety of personnel and the environment.

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