Linshang Chemical
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1,2-Dichloro-3-Methoxybenzene
Linshang Chemical
|
HS Code |
180473 |
| Chemical Formula | C7H6Cl2O |
| Molecular Weight | 177.028 g/mol |
| Appearance | A colorless to light yellow liquid |
| Boiling Point | Around 215 - 217 °C |
| Density | Approx. 1.32 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, ether |
| Flash Point | Likely to be around 90 - 95 °C |
| Vapor Pressure | Low vapor pressure at room temperature |
As an accredited 1,2-Dichloro-3-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 1,2 - dichloro - 3 - methoxybenzene packaged in a sealed, chemical - resistant bottle. |
| Storage | 1,2 - Dichloro - 3 - methoxybenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials, as it may react with certain substances. Store separately from oxidizing agents, acids, and bases to prevent potential chemical reactions. |
| Shipping | 1,2 - dichloro - 3 - methoxybenzene is shipped in sealed, corrosion - resistant containers. Packaging ensures protection from external elements. Shipments follow strict chemical transportation regulations to safeguard safety during transit. |
Competitive 1,2-Dichloro-3-Methoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1,2-Dichloro-3-Methoxybenzene in China?
As a trusted 1,2-Dichloro-3-Methoxybenzene manufacturer, we deliver:
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1,2-Dichloro-3-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1,2-dichloro-3-methoxybenzene?
1,2-Dioxide-3-methoxybenzene, that is, guaiacol, is widely used.
In the field of medicine, it is an important raw material for the synthesis of drugs. For example, it can be used to prepare expectorant and cough-relieving drugs. By stimulating the respiratory mucosa, it increases secretion and dilutes sputum, making it easy to cough up. It has a significant effect on relieving cough and improving respiratory symptoms. It can also be used to synthesize antibacterial and anti-inflammatory drugs. With its specific chemical structure, it shows the ability to inhibit the growth and reproduction of bacteria and escort human health.
In the fragrance industry, it emits a unique aroma and is often used as a fragrance ingredient. When adding perfume, air freshener, detergent and other products, it can give the product a pleasant fragrance, add product charm, and enhance the user's olfactory experience.
In chemical production, it is a key intermediate for synthetic resins, dyes and other chemical products. After a series of chemical reactions, it can be converted into resin materials with different properties, which can be used in the production of coatings, adhesives, etc.; it can also be used as a basic raw material for synthesizing specific dyes, providing rich color choices for textile, printing and dyeing and other industries.
In the food industry, although the dosage is limited, it is occasionally used in the formulation of specific food additives. Its special flavor can play a role in enhancing the flavor and flavor of certain foods, optimizing the taste and flavor of food, and meeting consumers' needs for unique flavors.
In the field of medicine, it is an important raw material for the synthesis of drugs. For example, it can be used to prepare expectorant and cough-relieving drugs. By stimulating the respiratory mucosa, it increases secretion and dilutes sputum, making it easy to cough up. It has a significant effect on relieving cough and improving respiratory symptoms. It can also be used to synthesize antibacterial and anti-inflammatory drugs. With its specific chemical structure, it shows the ability to inhibit the growth and reproduction of bacteria and escort human health.
In the fragrance industry, it emits a unique aroma and is often used as a fragrance ingredient. When adding perfume, air freshener, detergent and other products, it can give the product a pleasant fragrance, add product charm, and enhance the user's olfactory experience.
In chemical production, it is a key intermediate for synthetic resins, dyes and other chemical products. After a series of chemical reactions, it can be converted into resin materials with different properties, which can be used in the production of coatings, adhesives, etc.; it can also be used as a basic raw material for synthesizing specific dyes, providing rich color choices for textile, printing and dyeing and other industries.
In the food industry, although the dosage is limited, it is occasionally used in the formulation of specific food additives. Its special flavor can play a role in enhancing the flavor and flavor of certain foods, optimizing the taste and flavor of food, and meeting consumers' needs for unique flavors.
What are the physical properties of 1,2-dichloro-3-methoxybenzene?
1% 2C2 + - + dioxy + - + 3 + - + methoxy benzyl matter is rational, because it has the same external characteristics, which is essential in general work and use.
First, the shape of this object is often liquid, and the ground is clear. It is similar to the flow of color, clear and less expensive. This shape is easy to operate like water, such as injection, mixing, etc. Its fluidity is good, and it can be flowed in the container, not because it is sticky.
Second, it can be melted and boiled. Its melting is low, and it can be dissolved into liquid when it is small. This characteristic can save a lot of energy consumption in the work that needs to be shaped. The boiling phase is high, and under normal conditions, it can be fixed by holding the liquid, and it is not easy to vaporize and dissipate due to low-degree waves, ensuring the convenience of its storage and use.
Third, the density of this material is slightly heavier than that of water. When it is put into water, it sinks to the bottom. This density characteristic, in the work of separation and extraction, can be used to make use of the difference in the density of other substances. It is especially convenient for the purpose of separation by methods such as sedimentation.
Fourth, the solubility of this substance also has its own characteristics. It is soluble in general, such as ethanol and ether, but its solubility in water is limited. This solubility property allows it to be used in synthetic processes, etc., as a good reaction medium, to blend with other substances, and to promote the benefit of reaction.
Fifth, the taste of this substance is subtle and special, not pungent, but also discernible. This taste property, in the context of using this substance, does not cause intense sensory stimulation, and can also be used by operators to test the taste and identify the existence and quality of this substance.
First, the shape of this object is often liquid, and the ground is clear. It is similar to the flow of color, clear and less expensive. This shape is easy to operate like water, such as injection, mixing, etc. Its fluidity is good, and it can be flowed in the container, not because it is sticky.
Second, it can be melted and boiled. Its melting is low, and it can be dissolved into liquid when it is small. This characteristic can save a lot of energy consumption in the work that needs to be shaped. The boiling phase is high, and under normal conditions, it can be fixed by holding the liquid, and it is not easy to vaporize and dissipate due to low-degree waves, ensuring the convenience of its storage and use.
Third, the density of this material is slightly heavier than that of water. When it is put into water, it sinks to the bottom. This density characteristic, in the work of separation and extraction, can be used to make use of the difference in the density of other substances. It is especially convenient for the purpose of separation by methods such as sedimentation.
Fourth, the solubility of this substance also has its own characteristics. It is soluble in general, such as ethanol and ether, but its solubility in water is limited. This solubility property allows it to be used in synthetic processes, etc., as a good reaction medium, to blend with other substances, and to promote the benefit of reaction.
Fifth, the taste of this substance is subtle and special, not pungent, but also discernible. This taste property, in the context of using this substance, does not cause intense sensory stimulation, and can also be used by operators to test the taste and identify the existence and quality of this substance.
What are the chemical properties of 1,2-dichloro-3-methoxybenzene?
What is the chemical property of 1% 2C2 + - + dioxy + - + 3 + - + methoxybenzene? This is a question about the characteristics of chemical substances, and I will describe it in ancient Chinese in the style of "Tiangong Kaiwu".
1% 2C2 -dioxy-3 -methoxybenzene, which is an organic compound with unique chemical properties. In this substance, the dioxy structure is connected to methoxybenzene, which makes its properties quite different.
From the perspective of its structure, the dioxy part may give it a certain oxidizing property, but this oxidizing property is not as violent as a strong oxidizing agent, but relatively mild. When encountering some reducing substances, oxidation and reduction reactions may occur. Although it is not violent, it can change the structure and properties of the related substances.
Methoxybenzene part, the presence of methyl affects the electron cloud distribution of the molecule. Methyl is the power supply group, which can increase the electron cloud density of the benzene ring, making the benzene ring more prone to electrophilic substitution. The connection of the oxygen group to the benzene ring also affects the reactivity and selectivity of the benzene ring. Under suitable conditions, it can be substituted with electrophilic reagents such as halogenation reagents, nitrogenation reagents, etc., and the corresponding substituents are introduced at specific positions in the benzene ring.
Furthermore, 1% 2C2-dioxy-3-methoxybenzene contains different groups, or can participate in many organic synthesis reactions. In the field of organic synthesis, it can be used as a key intermediate, which can be converted into other more complex organic compounds with special functions through a series of reactions.
However, it should be noted that the chemical properties of this substance are also significantly affected by external conditions. Temperature, solvents, catalysts and other factors can change the rate and direction of chemical reactions. At high temperatures, its reactivity or enhancement can promote some reactions that are difficult to occur at room temperature; and specific solvents may dissolve this substance and change the interaction between its molecules, thereby affecting the selectivity of the reaction. The addition of a catalyst can further reduce the activation energy of the reaction, making the reaction more likely to occur.
1% 2C2 -dioxy-3 -methoxybenzene, which is an organic compound with unique chemical properties. In this substance, the dioxy structure is connected to methoxybenzene, which makes its properties quite different.
From the perspective of its structure, the dioxy part may give it a certain oxidizing property, but this oxidizing property is not as violent as a strong oxidizing agent, but relatively mild. When encountering some reducing substances, oxidation and reduction reactions may occur. Although it is not violent, it can change the structure and properties of the related substances.
Methoxybenzene part, the presence of methyl affects the electron cloud distribution of the molecule. Methyl is the power supply group, which can increase the electron cloud density of the benzene ring, making the benzene ring more prone to electrophilic substitution. The connection of the oxygen group to the benzene ring also affects the reactivity and selectivity of the benzene ring. Under suitable conditions, it can be substituted with electrophilic reagents such as halogenation reagents, nitrogenation reagents, etc., and the corresponding substituents are introduced at specific positions in the benzene ring.
Furthermore, 1% 2C2-dioxy-3-methoxybenzene contains different groups, or can participate in many organic synthesis reactions. In the field of organic synthesis, it can be used as a key intermediate, which can be converted into other more complex organic compounds with special functions through a series of reactions.
However, it should be noted that the chemical properties of this substance are also significantly affected by external conditions. Temperature, solvents, catalysts and other factors can change the rate and direction of chemical reactions. At high temperatures, its reactivity or enhancement can promote some reactions that are difficult to occur at room temperature; and specific solvents may dissolve this substance and change the interaction between its molecules, thereby affecting the selectivity of the reaction. The addition of a catalyst can further reduce the activation energy of the reaction, making the reaction more likely to occur.
What are the synthesis methods of 1,2-dichloro-3-methoxybenzene?
The synthesis of 1% 2C2 + - + dioxy + - + 3 + - + methoxybenzene has various ways, let me tell you one by one.
First, the structure can be constructed from simple raw materials through a multi-step reaction. First, take a suitable benzene derivative with a modifiable group on it. For example, starting with halobenzene, use a nucleophilic substitution reaction to replace the halogen atom with a methoxy group. This step requires selecting a suitable base and reaction conditions to increase the reaction efficiency and selectivity. Common bases such as potassium carbonate are heated and stirred in an organic solvent, and the halobenzene reacts with nucleophiles such as sodium methoxide to obtain methoxybenzene derivatives.
Then, a dioxy structure is introduced. It can be achieved by cyclization reaction. For example, the phenolic hydroxyl group is used with an ortho-halogen atom or other suitable leaving group, and the nucleophilic substitution reaction is carried out in the molecule under the catalysis of alkali to form a dioxane heterocycle. This process is very critical to the control of the reaction temperature and the proportion of the reactants. A slight difference in the pool will affect the yield and product purity.
Second, another route can also be designed through reverse synthesis analysis. Starting from the target molecule, it is disassembled into several simple fragments, and then these fragments are synthesized separately, and then spliced by coupling reaction. For example, methoxybenzene is connected to a fragment containing a dioxy structure through a palladium-catalyzed coupling reaction. This requires precise selection of coupling reagents, ligands and reaction solvents to promote the smooth progress of the reaction. Palladium catalysts have high activity but are expensive, so ligand selection is crucial to regulate catalyst activity and selectivity, making the reaction efficient and economical.
Or biosynthesis can be considered, although it is more complex, it has unique advantages. Using the catalytic properties of microorganisms or enzymes, it is synthesized under mild conditions. Enzymes are highly specific and can precisely catalyze specific reactions and reduce the occurrence of side reactions. However, it is not easy to build a biosynthetic system. It is necessary to study the culture of microorganisms or enzymes and the optimization of reaction conditions in depth in order to effectively achieve the synthesis of target molecules.
First, the structure can be constructed from simple raw materials through a multi-step reaction. First, take a suitable benzene derivative with a modifiable group on it. For example, starting with halobenzene, use a nucleophilic substitution reaction to replace the halogen atom with a methoxy group. This step requires selecting a suitable base and reaction conditions to increase the reaction efficiency and selectivity. Common bases such as potassium carbonate are heated and stirred in an organic solvent, and the halobenzene reacts with nucleophiles such as sodium methoxide to obtain methoxybenzene derivatives.
Then, a dioxy structure is introduced. It can be achieved by cyclization reaction. For example, the phenolic hydroxyl group is used with an ortho-halogen atom or other suitable leaving group, and the nucleophilic substitution reaction is carried out in the molecule under the catalysis of alkali to form a dioxane heterocycle. This process is very critical to the control of the reaction temperature and the proportion of the reactants. A slight difference in the pool will affect the yield and product purity.
Second, another route can also be designed through reverse synthesis analysis. Starting from the target molecule, it is disassembled into several simple fragments, and then these fragments are synthesized separately, and then spliced by coupling reaction. For example, methoxybenzene is connected to a fragment containing a dioxy structure through a palladium-catalyzed coupling reaction. This requires precise selection of coupling reagents, ligands and reaction solvents to promote the smooth progress of the reaction. Palladium catalysts have high activity but are expensive, so ligand selection is crucial to regulate catalyst activity and selectivity, making the reaction efficient and economical.
Or biosynthesis can be considered, although it is more complex, it has unique advantages. Using the catalytic properties of microorganisms or enzymes, it is synthesized under mild conditions. Enzymes are highly specific and can precisely catalyze specific reactions and reduce the occurrence of side reactions. However, it is not easy to build a biosynthetic system. It is necessary to study the culture of microorganisms or enzymes and the optimization of reaction conditions in depth in order to effectively achieve the synthesis of target molecules.
What are the precautions for storing and transporting 1,2-dichloro-3-methoxybenzene?
1% 2C2 + - + dioxy + - + 3 + - + methyl hydroxybenzene should pay attention to the following matters during storage and transportation:
First, it is related to storage. This substance should be stored in a cool, dry and well-ventilated place. Due to its nature or sensitivity to temperature and humidity, if the environment is humid, it is easy to cause deterioration; if the temperature is too high, it may trigger a chemical reaction, resulting in damage to its stability. Therefore, the selected storage place should try to avoid direct sunlight and heat sources to prevent excessive temperature fluctuations. And it needs to be stored separately from oxidants, acids, bases, etc. Because of its chemical activity, contact with these substances may cause violent reactions and endanger safety.
Second, about transportation. When transporting, it is necessary to ensure that the packaging is complete and tightly sealed. Packaging materials should have good protective properties and can resist external vibration, collision and friction to prevent material leakage due to package damage. Transportation vehicles need to be equipped with corresponding fire equipment and leakage emergency treatment equipment to deal with emergencies. During transportation, drivers and escorts need to pay close attention to the status of the goods, strictly abide by the transportation operation procedures, avoid violent actions such as sudden braking and sharp turns, and ensure smooth transportation. And the transportation route should be planned in advance to avoid densely populated areas and environmentally sensitive areas. In the event of leakage, the harm can be minimized. Therefore, during the storage and transportation of 1% 2C2 + - + dioxy + - + 3 + - + methyl hydroxybenzene, the above points should be carefully followed to ensure its safety and stability.
First, it is related to storage. This substance should be stored in a cool, dry and well-ventilated place. Due to its nature or sensitivity to temperature and humidity, if the environment is humid, it is easy to cause deterioration; if the temperature is too high, it may trigger a chemical reaction, resulting in damage to its stability. Therefore, the selected storage place should try to avoid direct sunlight and heat sources to prevent excessive temperature fluctuations. And it needs to be stored separately from oxidants, acids, bases, etc. Because of its chemical activity, contact with these substances may cause violent reactions and endanger safety.
Second, about transportation. When transporting, it is necessary to ensure that the packaging is complete and tightly sealed. Packaging materials should have good protective properties and can resist external vibration, collision and friction to prevent material leakage due to package damage. Transportation vehicles need to be equipped with corresponding fire equipment and leakage emergency treatment equipment to deal with emergencies. During transportation, drivers and escorts need to pay close attention to the status of the goods, strictly abide by the transportation operation procedures, avoid violent actions such as sudden braking and sharp turns, and ensure smooth transportation. And the transportation route should be planned in advance to avoid densely populated areas and environmentally sensitive areas. In the event of leakage, the harm can be minimized. Therefore, during the storage and transportation of 1% 2C2 + - + dioxy + - + 3 + - + methyl hydroxybenzene, the above points should be carefully followed to ensure its safety and stability.
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