Linshang Chemical
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1,2-Dichloro-3-Nitro-5-(Trifluoromethyl)Benzene
Linshang Chemical
|
HS Code |
955623 |
| Chemical Formula | C7H2Cl2F3NO2 |
| Molar Mass | 260.00 g/mol |
| Appearance | Solid (Typical for this type of compound) |
| Physical State At Room Temp | Solid |
| Melting Point | Data needed from reliable source |
| Boiling Point | Data needed from reliable source |
| Solubility In Water | Low (due to non - polar nature of the molecule) |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, toluene |
| Density | Data needed from reliable source |
| Vapor Pressure | Low (due to its solid state at room temp) |
| Odor | Pungent (common for halogen - and nitro - containing aromatic compounds) |
| Stability | Stable under normal conditions but can react under specific chemical conditions |
As an accredited 1,2-Dichloro-3-Nitro-5-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1,2 - Dichloro - 3 - nitro - 5 - (trifluoromethyl)benzene: 500g in a sealed, corrosion - resistant plastic bottle. |
| Storage | 1,2 - Dichloro - 3 - nitro - 5 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. It should be kept in a tightly closed container to prevent vapor leakage. Store it separately from oxidizing agents, reducing agents, and other incompatible substances to avoid potential reactions. |
| Shipping | 1,2 - Dichloro - 3 - nitro - 5 - (trifluoromethyl)benzene is shipped in well - sealed, corrosion - resistant containers. Compliance with chemical transportation regulations ensures safe handling during transit to prevent any environmental or safety hazards. |
Competitive 1,2-Dichloro-3-Nitro-5-(Trifluoromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1,2-Dichloro-3-Nitro-5-(Trifluoromethyl)Benzene in China?
As a trusted 1,2-Dichloro-3-Nitro-5-(Trifluoromethyl)Benzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1,2-Dichloro-3-Nitro-5-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1,2-dichloro-3-nitro-5- (trifluoromethyl) benzene?
1% 2C2-dioxo-3-furanyl-5- (trifluoromethyl) pyridine has a wide range of uses. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create a variety of specific drugs. For example, in the research and development process of antimalarial drugs, with its special chemical structure, it can combine with specific targets in the malaria parasite, thereby interfering with the normal metabolism and reproduction of the malaria parasite, achieving good antimalarial effect.
In the field of pesticides, this compound also shows unique value. The insecticides developed on its basis have highly effective contact and stomach toxicity effects on many pests. Due to its stable chemical properties, it can maintain a certain period of efficacy in the environment for a certain period of time, and at the same time, it is less toxic to mammals. Therefore, while ensuring agricultural production and controlling pests, it can minimize the harm to the ecological environment and non-target organisms.
In addition, in the field of materials science, 1% 2C2-dioxy-3-furyl-5- (trifluoromethyl) pyridine can also play an important role. It can be used to prepare polymer materials with special properties, such as giving materials excellent heat resistance, corrosion resistance and optical properties. By introducing it into the structure of polymer, the physical and chemical properties of materials can be effectively improved to meet the needs of different fields for special materials, such as aerospace, electronic information and other high-end industries.
In the field of pesticides, this compound also shows unique value. The insecticides developed on its basis have highly effective contact and stomach toxicity effects on many pests. Due to its stable chemical properties, it can maintain a certain period of efficacy in the environment for a certain period of time, and at the same time, it is less toxic to mammals. Therefore, while ensuring agricultural production and controlling pests, it can minimize the harm to the ecological environment and non-target organisms.
In addition, in the field of materials science, 1% 2C2-dioxy-3-furyl-5- (trifluoromethyl) pyridine can also play an important role. It can be used to prepare polymer materials with special properties, such as giving materials excellent heat resistance, corrosion resistance and optical properties. By introducing it into the structure of polymer, the physical and chemical properties of materials can be effectively improved to meet the needs of different fields for special materials, such as aerospace, electronic information and other high-end industries.
What are the physical properties of 1,2-dichloro-3-nitro-5- (trifluoromethyl) benzene?
1% 2C2-dideuterium-3-hydroxy-5- (trifluoromethyl) pyridine This substance has specific physical properties. Its shape may be a colorless to pale yellow liquid, and it can be viewed clearly. Under normal light and room temperature, its chemical state can be maintained relatively stable.
Regarding the boiling point, due to the intermolecular forces and structure, it is about a specific temperature range. At this temperature, the substance changes from liquid to gaseous state. This temperature is a characterization of the energy required for the gasification of the substance, reflecting the difficulty of the molecule breaking free from each other's attractive forces. Its melting point is also fixed, which is the critical temperature between solid and liquid states. At this point, the lattice energy and the thermal motion of the molecule can reach equilibrium, resulting in the transformation of the material form.
In terms of solubility, in organic solvents, due to the principle of similarity and dissolution, if the molecular polarity of the organic solvent is similar to that of the compound, or if it can form specific intermolecular forces, such as hydrogen bonds, van der Waals forces, etc. In water, the solubility may be limited due to the difference between the polarity of water and the structure of the compound.
Density is also an important physical property, which characterizes the mass per unit volume, and is related to the packing density and relative molecular mass of the molecule. This value is related to the sedimentation or floating state of the substance in the mixed system, and is important for chemical operations and separation processes.
The refractive index is also one of its characteristics, reflecting the degree of refraction of light when propagating in the material, and is related to the distribution of electron clouds and structural symmetry of molecules. It can be used for the detection and qualitative analysis of material purity.
In addition, its vapor pressure is also a non-negligible property. At a certain temperature, when a substance is in gas-liquid equilibrium, the pressure of the gas phase is the vapor pressure, which is related to the thermal motion of molecules and the ability to escape from the liquid surface. It has a great impact on the volatilization and diffusion of substances.
Regarding the boiling point, due to the intermolecular forces and structure, it is about a specific temperature range. At this temperature, the substance changes from liquid to gaseous state. This temperature is a characterization of the energy required for the gasification of the substance, reflecting the difficulty of the molecule breaking free from each other's attractive forces. Its melting point is also fixed, which is the critical temperature between solid and liquid states. At this point, the lattice energy and the thermal motion of the molecule can reach equilibrium, resulting in the transformation of the material form.
In terms of solubility, in organic solvents, due to the principle of similarity and dissolution, if the molecular polarity of the organic solvent is similar to that of the compound, or if it can form specific intermolecular forces, such as hydrogen bonds, van der Waals forces, etc. In water, the solubility may be limited due to the difference between the polarity of water and the structure of the compound.
Density is also an important physical property, which characterizes the mass per unit volume, and is related to the packing density and relative molecular mass of the molecule. This value is related to the sedimentation or floating state of the substance in the mixed system, and is important for chemical operations and separation processes.
The refractive index is also one of its characteristics, reflecting the degree of refraction of light when propagating in the material, and is related to the distribution of electron clouds and structural symmetry of molecules. It can be used for the detection and qualitative analysis of material purity.
In addition, its vapor pressure is also a non-negligible property. At a certain temperature, when a substance is in gas-liquid equilibrium, the pressure of the gas phase is the vapor pressure, which is related to the thermal motion of molecules and the ability to escape from the liquid surface. It has a great impact on the volatilization and diffusion of substances.
Is the chemical properties of 1,2-dichloro-3-nitro-5- (trifluoromethyl) benzene stable?
The chemical properties of 1% 2C2-dichloro-3-cyano-5- (trifluoromethyl) pyridine are relatively stable. Cover because of its structure, halogen atom, cyano group and trifluoromethyl all have certain characteristics.
Among halogen atoms, chlorine atoms have strong electronegativity, which can change the distribution of electron clouds in molecules and enhance molecular polarity. However, it is connected to the pyridine ring, and the conjugate system of the pyridine ring restricts the activity of the chlorine atom. The pyridine ring is an electron-rich aromatic system. The lone pair of chlorine atoms participates in the conjugation of electrons, which makes the C-Cl bond have some double bond properties and the bond energy increases. Therefore, the chlorine atom substitution reaction is more difficult than the halogenated alkanes, and it is not easy to leave easily. Reactions such as nucleophilic substitution occur.
Cyano-CN has strong electron-absorbing properties, which can further reduce the electron cloud density of the pyridine ring and enhance the stability of the pyridine ring. At the same time, the cyanyl group itself has a relatively stable triple bond structure, and it is not easy to break and undergo addition reactions under general conditions. Specific reagents and conditions are required, such as hydrolysis under strong acid or strong base
Trifluoromethyl-CF
is also a strong electron-withdrawing group. Because of its extreme electronegativity of fluorine atoms, the group as a whole presents a strong electron-withdrawing effect. This effect not only affects the distribution of electron clouds in the pyridine ring, but also can be transmitted to the whole molecule through induction effect to stabilize the molecular structure. And trifluoromethyl has high bond energy, short bond length, small radius of F atom, small mutual repulsion force, stable structure, and is not easy to react when attacked by general reagents.
In summary, 1% 2C2-dichloro-3-cyano-5- (trifluoromethyl) pyridine is relatively stable in overall chemical properties due to the characteristics and interactions of various groups, and it is not easy to undergo violent chemical reactions under normal conditions. Special reaction conditions and reagents are required to initiate corresponding chemical changes.
Among halogen atoms, chlorine atoms have strong electronegativity, which can change the distribution of electron clouds in molecules and enhance molecular polarity. However, it is connected to the pyridine ring, and the conjugate system of the pyridine ring restricts the activity of the chlorine atom. The pyridine ring is an electron-rich aromatic system. The lone pair of chlorine atoms participates in the conjugation of electrons, which makes the C-Cl bond have some double bond properties and the bond energy increases. Therefore, the chlorine atom substitution reaction is more difficult than the halogenated alkanes, and it is not easy to leave easily. Reactions such as nucleophilic substitution occur.
Cyano-CN has strong electron-absorbing properties, which can further reduce the electron cloud density of the pyridine ring and enhance the stability of the pyridine ring. At the same time, the cyanyl group itself has a relatively stable triple bond structure, and it is not easy to break and undergo addition reactions under general conditions. Specific reagents and conditions are required, such as hydrolysis under strong acid or strong base
Trifluoromethyl-CF
is also a strong electron-withdrawing group. Because of its extreme electronegativity of fluorine atoms, the group as a whole presents a strong electron-withdrawing effect. This effect not only affects the distribution of electron clouds in the pyridine ring, but also can be transmitted to the whole molecule through induction effect to stabilize the molecular structure. And trifluoromethyl has high bond energy, short bond length, small radius of F atom, small mutual repulsion force, stable structure, and is not easy to react when attacked by general reagents.
In summary, 1% 2C2-dichloro-3-cyano-5- (trifluoromethyl) pyridine is relatively stable in overall chemical properties due to the characteristics and interactions of various groups, and it is not easy to undergo violent chemical reactions under normal conditions. Special reaction conditions and reagents are required to initiate corresponding chemical changes.
What are the preparation methods of 1,2-dichloro-3-nitro-5- (trifluoromethyl) benzene?
1% 2C2-dichloro-3-cyano-5- (trifluoromethyl) pyridine is an important organic compound. Although its preparation method is not directly related to "Tiangong Kaiwu", it can be deduced from the ancient chemical process ideas and similar compound preparation ideas.
First, it can be started from pyridine derivatives. Although there is no modern advanced synthesis method in ancient times, it may have a certain understanding and utilization of natural nitrogen-containing heterocyclic compounds. Suitable natural products of pyridine can be found first, and natural products can be used as raw materials. By hydrolysis, oxidation, reduction and other basic chemical reactions, the desired substituents can be gradually introduced. For example, if a pyridine derivative with a similar structure is found, an oxidation reaction can be used. According to the ancient method of using air, saltpeter, etc. as oxidants, the specific position of the pyridine ring can be oxidized under appropriate conditions to create conditions for the subsequent introduction of substituents.
Second, about the introduction of chlorine atoms. Although there are no modern halogenating reagents in ancient times, it can be considered to borrow chlorine-containing natural minerals or simple chlorine-containing compounds. For example, using table salt (sodium chloride), although it was difficult to achieve by electrolysis in ancient times, it can be considered to try to make chlorine participate in the reaction in the form of hydrogen chloride gas and interact with pyridine derivatives to achieve chlorine atom substitution at high temperatures and in the presence of specific catalysts. However, this process requires finding a suitable catalyst. In ancient times, metal oxides, charcoal, etc. were used as catalysts. Through continuous exploration of the reaction temperature, time and the ratio of raw materials, chlorine atoms were precisely introduced to the 1,2 position.
The third, cyanyl group is introduced. In ancient times, cyanide-containing natural substances, such as some plant extracts or cyanide-containing components in minerals, can be used. By controlling the reaction conditions, cyanide-containing groups can undergo reactions such as nucleophilic substitution with pyridine derivatives and connect to the 3 position of the pyridine ring. This requires fine regulation of the reaction medium, pH, etc. Although there was no accurate detection method in ancient times, the reaction process can be judged by observing reaction phenomena such as color changes, precipitation formation, etc.
Fourth, the introduction of trifluoromethyl is quite difficult. In ancient times, there were no modern fluorine-containing reagents, but it is conceivable to borrow fluorine-containing natural minerals, through complex refining and transformation, first prepare simple fluorine-containing compounds, and then try to react with pyridine derivatives. Or through multi-step reactions, first form an active intermediate, and then combine the fluorine-containing part with it to achieve the introduction of trifluoromethyl based on 5 positions. The whole preparation process requires patience to try different reaction conditions and raw material combinations to achieve the preparation of the target product.
First, it can be started from pyridine derivatives. Although there is no modern advanced synthesis method in ancient times, it may have a certain understanding and utilization of natural nitrogen-containing heterocyclic compounds. Suitable natural products of pyridine can be found first, and natural products can be used as raw materials. By hydrolysis, oxidation, reduction and other basic chemical reactions, the desired substituents can be gradually introduced. For example, if a pyridine derivative with a similar structure is found, an oxidation reaction can be used. According to the ancient method of using air, saltpeter, etc. as oxidants, the specific position of the pyridine ring can be oxidized under appropriate conditions to create conditions for the subsequent introduction of substituents.
Second, about the introduction of chlorine atoms. Although there are no modern halogenating reagents in ancient times, it can be considered to borrow chlorine-containing natural minerals or simple chlorine-containing compounds. For example, using table salt (sodium chloride), although it was difficult to achieve by electrolysis in ancient times, it can be considered to try to make chlorine participate in the reaction in the form of hydrogen chloride gas and interact with pyridine derivatives to achieve chlorine atom substitution at high temperatures and in the presence of specific catalysts. However, this process requires finding a suitable catalyst. In ancient times, metal oxides, charcoal, etc. were used as catalysts. Through continuous exploration of the reaction temperature, time and the ratio of raw materials, chlorine atoms were precisely introduced to the 1,2 position.
The third, cyanyl group is introduced. In ancient times, cyanide-containing natural substances, such as some plant extracts or cyanide-containing components in minerals, can be used. By controlling the reaction conditions, cyanide-containing groups can undergo reactions such as nucleophilic substitution with pyridine derivatives and connect to the 3 position of the pyridine ring. This requires fine regulation of the reaction medium, pH, etc. Although there was no accurate detection method in ancient times, the reaction process can be judged by observing reaction phenomena such as color changes, precipitation formation, etc.
Fourth, the introduction of trifluoromethyl is quite difficult. In ancient times, there were no modern fluorine-containing reagents, but it is conceivable to borrow fluorine-containing natural minerals, through complex refining and transformation, first prepare simple fluorine-containing compounds, and then try to react with pyridine derivatives. Or through multi-step reactions, first form an active intermediate, and then combine the fluorine-containing part with it to achieve the introduction of trifluoromethyl based on 5 positions. The whole preparation process requires patience to try different reaction conditions and raw material combinations to achieve the preparation of the target product.
What should be paid attention to when storing and transporting 1,2-dichloro-3-nitro-5- (trifluoromethyl) benzene?
1% 2C2-dioxy-3-furanyl-5 - (trifluoromethyl) pyridine This compound should be stored and transported with the following key points:
One is temperature control. This compound is quite sensitive to temperature changes. Excessive temperature may cause it to decompose and deteriorate, and too low temperature may cause it to crystallize and precipitate, which affects quality and performance. Therefore, when storing, a constant temperature should be selected, generally 2-8 ° C. During transportation, effective temperature control measures should also be taken, such as refrigerated trucks or incubators, to ensure that the temperature fluctuates within the allowable range.
The second is about humidity prevention. Because of its certain hygroscopicity, it may cause chemical reactions after being damp, causing quality damage. The storage environment should be kept dry, and the humidity should be controlled at 40% - 60%. When transporting, the package must be tightly sealed, and a desiccant can be built in to prevent moisture from invading.
The third is packaging selection. Suitable packaging materials are required to ensure its chemical stability and sealing. Containers made of glass or plastic are commonly used, but their compatibility with compounds should be considered to prevent reactions. Warning labels and product information should be clearly marked on the outside of the package for easy identification and handling.
The fourth is to avoid contact with impurities. The compound is chemically active and easy to react with impurities. During storage and transportation, it is necessary to ensure that the container is clean and free of residual impurities. It is also necessary to avoid mixing and transportation with incompatible substances to prevent danger.
The fifth is to follow regulations and systems. The storage and transportation of such compounds must strictly abide by relevant national and local regulations and standards. Operators need to be professionally trained, familiar with operating procedures and emergency treatment methods. Transportation documents should be complete and detailed.
In short, 1% 2C2-dioxy-3-furyl-5 - (trifluoromethyl) pyridine should not be ignored in terms of temperature, humidity, packaging, impurities and regulations during storage and transportation, so as to ensure its safety and stability.
One is temperature control. This compound is quite sensitive to temperature changes. Excessive temperature may cause it to decompose and deteriorate, and too low temperature may cause it to crystallize and precipitate, which affects quality and performance. Therefore, when storing, a constant temperature should be selected, generally 2-8 ° C. During transportation, effective temperature control measures should also be taken, such as refrigerated trucks or incubators, to ensure that the temperature fluctuates within the allowable range.
The second is about humidity prevention. Because of its certain hygroscopicity, it may cause chemical reactions after being damp, causing quality damage. The storage environment should be kept dry, and the humidity should be controlled at 40% - 60%. When transporting, the package must be tightly sealed, and a desiccant can be built in to prevent moisture from invading.
The third is packaging selection. Suitable packaging materials are required to ensure its chemical stability and sealing. Containers made of glass or plastic are commonly used, but their compatibility with compounds should be considered to prevent reactions. Warning labels and product information should be clearly marked on the outside of the package for easy identification and handling.
The fourth is to avoid contact with impurities. The compound is chemically active and easy to react with impurities. During storage and transportation, it is necessary to ensure that the container is clean and free of residual impurities. It is also necessary to avoid mixing and transportation with incompatible substances to prevent danger.
The fifth is to follow regulations and systems. The storage and transportation of such compounds must strictly abide by relevant national and local regulations and standards. Operators need to be professionally trained, familiar with operating procedures and emergency treatment methods. Transportation documents should be complete and detailed.
In short, 1% 2C2-dioxy-3-furyl-5 - (trifluoromethyl) pyridine should not be ignored in terms of temperature, humidity, packaging, impurities and regulations during storage and transportation, so as to ensure its safety and stability.
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