Linshang Chemical
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1,2-Dichloro-4-(Chloromethyl)Benzene
Linshang Chemical
|
HS Code |
135396 |
| Chemical Formula | C7H5Cl3 |
| Molecular Weight | 195.47 |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 246 - 248 °C |
| Melting Point | 3 - 5 °C |
| Density | 1.386 g/cm³ (20 °C) |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, ether |
| Vapor Pressure | Low |
| Flash Point | 107 °C |
| Odor | Pungent |
As an accredited 1,2-Dichloro-4-(Chloromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram bottle of 1,2 - dichloro - 4-(chloromethyl)benzene, tightly sealed. |
| Storage | 1,2 - Dichloro - 4 - (chloromethyl)benzene should be stored in a cool, well - ventilated area away from heat and ignition sources. Keep it in a tightly closed container to prevent vapor release. Store it separately from oxidizing agents and reactive materials. Use storage cabinets designed for hazardous chemicals, and ensure proper labeling for easy identification and safety compliance. |
| Shipping | 1,2 - dichloro - 4 - (chloromethyl)benzene is a chemical that must be shipped in accordance with strict hazardous materials regulations. It should be properly packaged in corrosion - resistant containers, labeled clearly, and transported by carriers approved for such chemicals. |
Competitive 1,2-Dichloro-4-(Chloromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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What are the physical properties of 1,2-dichloro-4- (chloromethyl) benzene?
1% 2C2-dichloro-4- (chloromethyl) benzene, this substance is an organic compound, its physical properties are as follows:
Looking at it, it is mostly colorless to light yellow liquid at room temperature, and the quality is clear. Smell it, it has a special irritating odor, which can be detected at a certain distance, but its taste is not pleasant, but will cause irritation to the nasal cavity, respiratory tract, etc.
In terms of its melting point, the melting point is about -20 ° C, and the boiling point is between 208-212 ° C. This boiling point characteristic causes it to exist as a liquid at room temperature and pressure. When the temperature drops below the melting point, it begins to solidify into a solid state; if the temperature rises above the boiling point, it will vaporize into a gaseous state.
When it comes to density, its density is greater than that of water, about 1.26 g/cm ³. Therefore, if it is mixed with water, it will sink to the bottom of the water and form a layered state with water.
In terms of solubility, it is extremely difficult to dissolve in water. Because it is an organic compound, the molecular polarity is weak, while water is a polar solvent. According to the principle of "similar miscibility", the two are difficult to dissolve. However, it has good solubility in many organic solvents, such as ethanol, ether, acetone, etc., and can be miscible with these organic solvents in any ratio.
Volatility, relatively speaking, has a certain degree of volatility. In an open environment, it will gradually evaporate into the air, and its volatilization rate is affected by factors such as ambient temperature, humidity, and ventilation. The higher the temperature, the better the ventilation, and the faster the evaporation.
Looking at it, it is mostly colorless to light yellow liquid at room temperature, and the quality is clear. Smell it, it has a special irritating odor, which can be detected at a certain distance, but its taste is not pleasant, but will cause irritation to the nasal cavity, respiratory tract, etc.
In terms of its melting point, the melting point is about -20 ° C, and the boiling point is between 208-212 ° C. This boiling point characteristic causes it to exist as a liquid at room temperature and pressure. When the temperature drops below the melting point, it begins to solidify into a solid state; if the temperature rises above the boiling point, it will vaporize into a gaseous state.
When it comes to density, its density is greater than that of water, about 1.26 g/cm ³. Therefore, if it is mixed with water, it will sink to the bottom of the water and form a layered state with water.
In terms of solubility, it is extremely difficult to dissolve in water. Because it is an organic compound, the molecular polarity is weak, while water is a polar solvent. According to the principle of "similar miscibility", the two are difficult to dissolve. However, it has good solubility in many organic solvents, such as ethanol, ether, acetone, etc., and can be miscible with these organic solvents in any ratio.
Volatility, relatively speaking, has a certain degree of volatility. In an open environment, it will gradually evaporate into the air, and its volatilization rate is affected by factors such as ambient temperature, humidity, and ventilation. The higher the temperature, the better the ventilation, and the faster the evaporation.
What are the chemical properties of 1,2-dichloro-4- (chloromethyl) benzene?
1% 2C2-dibromo-4- (bromomethyl) benzene-based organic compounds, with the following chemical properties:
- ** Nucleophilic substitution reaction **: Because its structure contains bromine atoms and bromomethyl, nucleophilic substitution can occur. Bromine atoms are highly active. When encountering nucleophilic reagents, nucleophilic reagents will attack bromine atoms connected to carbon, and bromine ions will leave to form new compounds. For example, when co-heated with an aqueous solution of sodium hydroxide, hydroxyl groups will replace bromine atoms to give compounds containing hydroxyl groups. Bromomethyl groups can also undergo nucleophilic substitution, such as reacting with sodium alcohol, alkoxy groups replace bromine in methyl to form ether compounds.
- ** Halogenation Reaction **: The benzene ring is affected by the substituent group, the electron cloud density changes, and halogenation can occur under suitable conditions. In the presence of catalysts such as iron filings or iron tribromide, and further react with bromine, bromine atoms can replace hydrogen atoms at other positions on the benzene ring. The specific substitution position is related to the localization effect of the substituent group. Because it contains multiple bromine atoms, it can participate in the construction of complex organic halide structures and is used to extend the carbon chain or introduce other functional groups in organic synthesis.
- ** Redox Reaction **: Although it is an atypical redox active group, it can react under the action of a specific strong oxidant or reducing agent. For example, in case of strong oxidants, the benzene ring side chain bromomethyl may be oxidized to form oxygenated compounds such as carboxyl groups or aldehyde groups; under suitable reduction conditions, bromine atoms may be reduced to hydrogen atoms to debromine the compound.
- ** Polymerization **: If combined with compounds containing active double bonds or other polymerizable functional groups, under the action of initiators, it may participate in the polymerization reaction to form polymers containing this structural unit, expanding its application in the field of polymer materials.
- ** Nucleophilic substitution reaction **: Because its structure contains bromine atoms and bromomethyl, nucleophilic substitution can occur. Bromine atoms are highly active. When encountering nucleophilic reagents, nucleophilic reagents will attack bromine atoms connected to carbon, and bromine ions will leave to form new compounds. For example, when co-heated with an aqueous solution of sodium hydroxide, hydroxyl groups will replace bromine atoms to give compounds containing hydroxyl groups. Bromomethyl groups can also undergo nucleophilic substitution, such as reacting with sodium alcohol, alkoxy groups replace bromine in methyl to form ether compounds.
- ** Halogenation Reaction **: The benzene ring is affected by the substituent group, the electron cloud density changes, and halogenation can occur under suitable conditions. In the presence of catalysts such as iron filings or iron tribromide, and further react with bromine, bromine atoms can replace hydrogen atoms at other positions on the benzene ring. The specific substitution position is related to the localization effect of the substituent group. Because it contains multiple bromine atoms, it can participate in the construction of complex organic halide structures and is used to extend the carbon chain or introduce other functional groups in organic synthesis.
- ** Redox Reaction **: Although it is an atypical redox active group, it can react under the action of a specific strong oxidant or reducing agent. For example, in case of strong oxidants, the benzene ring side chain bromomethyl may be oxidized to form oxygenated compounds such as carboxyl groups or aldehyde groups; under suitable reduction conditions, bromine atoms may be reduced to hydrogen atoms to debromine the compound.
- ** Polymerization **: If combined with compounds containing active double bonds or other polymerizable functional groups, under the action of initiators, it may participate in the polymerization reaction to form polymers containing this structural unit, expanding its application in the field of polymer materials.
What are the industrial applications of 1,2-dichloro-4- (chloromethyl) benzene?
1% 2C2-dichloro-4- (chloromethyl) benzene, which is widely used in industry. In the field of synthetic materials, it is a key monomer for the preparation of special engineering plastics. After a specific polymerization reaction, polymer materials with excellent heat resistance and chemical corrosion resistance can be prepared, which are widely used in high-precision industries such as aerospace and electronics. Aerospace equipment needs to operate in extreme environments. Such materials can ensure the stability of components and ensure flight safety. In electronic and electrical appliances, it can improve the reliability of equipment under complex conditions.
In the pharmaceutical and chemical industry, it is also an important intermediate. Many antibacterial and anti-tumor drugs are synthesized by its participation. Through a series of chemical transformations, specific functional groups are introduced to build drug active structures. The drugs can effectively treat the corresponding diseases and contribute to human health and well-being.
In the field of pesticides, it can be used as a raw material for synthesizing highly efficient and low-toxic pesticides. After rational design and synthesis, pesticide products with high selectivity to pests and environmental friendliness can be obtained. It can accurately kill pests, reduce the impact on beneficial organisms, and is easy to degrade in the environment, reducing pollution residues, which is of great significance to the sustainable development of modern agriculture.
In addition, in the paint industry, the special coatings it participates in the synthesis have excellent weather resistance and wear resistance. It can be applied to the surface protection of building exterior walls and industrial equipment, prolonging the service life of objects and improving the appearance quality. All of this highlights the importance of 1% 2C2-dichloro-4- (chloromethyl) benzene in various industrial fields.
In the pharmaceutical and chemical industry, it is also an important intermediate. Many antibacterial and anti-tumor drugs are synthesized by its participation. Through a series of chemical transformations, specific functional groups are introduced to build drug active structures. The drugs can effectively treat the corresponding diseases and contribute to human health and well-being.
In the field of pesticides, it can be used as a raw material for synthesizing highly efficient and low-toxic pesticides. After rational design and synthesis, pesticide products with high selectivity to pests and environmental friendliness can be obtained. It can accurately kill pests, reduce the impact on beneficial organisms, and is easy to degrade in the environment, reducing pollution residues, which is of great significance to the sustainable development of modern agriculture.
In addition, in the paint industry, the special coatings it participates in the synthesis have excellent weather resistance and wear resistance. It can be applied to the surface protection of building exterior walls and industrial equipment, prolonging the service life of objects and improving the appearance quality. All of this highlights the importance of 1% 2C2-dichloro-4- (chloromethyl) benzene in various industrial fields.
What are the synthesis methods of 1,2-dichloro-4- (chloromethyl) benzene?
1% 2C2-dichloro-4- (chloromethyl) benzene is an important organic synthesis intermediate, and there are many synthesis methods. The following are common ones:
1. ** Using p-chlorotoluene as raw material **: p-chlorotoluene undergoes a side chain substitution reaction with chlorine under light conditions, which can introduce chlorine atoms on the methyl group to generate 1-chloromethyl-4-chlorobenzene, that is, the target product 1% 2C2-dichloro-4- (chloromethyl) benzene. This reaction uses light to homogenize chlorine gas to produce chlorine radicals, which are then substituted with hydrogen atoms on the p-chlorotoluene methyl group. The reaction conditions are relatively mild, and the equipment requirements are not high, but attention should be paid to control the degree of reaction to avoid the formation of polychlorinated by-products. Due to its wide source of raw materials p-chlorotoluene and moderate price, this method is widely used.
2. ** Using benzene as the starting material **: Benzene is first alkylated with chloromethyl chloride under the catalysis of Lewis acid (such as aluminum trichloride) to form p-chloromethylbenzene; after that, p-chloromethylbenzene and chlorine are introduced into the ortho-position of the benzene ring under the action of light or initiator to obtain 1% 2C2-dichloro-4- (chloromethyl) benzene. This route has a little more steps, but the raw material benzene is inexpensive, and the reaction selectivity of each step is good, so the yield can be improved by optimizing the reaction conditions. However, the Fu-gram alkylation reaction requires an anhydrous environment and the use of corrosive Lewis acid, which requires strict operation.
3. ** Using p-dichlorobenzene as raw material **: The chloromethylation reaction of p-dichlorobenzene with formaldehyde and hydrogen chloride occurs in the presence of a specific catalyst (such as zinc salt, etc.), directly generating 1% 2C2 -dichloro-4- (chloromethyl) benzene. This reaction has good atomic economy and theoretically high utilization of raw materials. However, the reaction conditions are more demanding, requiring high catalyst activity and selectivity, and parameters such as reaction temperature, pressure, and raw material ratio need to be precisely controlled to ensure the yield and purity of the target product.
1. ** Using p-chlorotoluene as raw material **: p-chlorotoluene undergoes a side chain substitution reaction with chlorine under light conditions, which can introduce chlorine atoms on the methyl group to generate 1-chloromethyl-4-chlorobenzene, that is, the target product 1% 2C2-dichloro-4- (chloromethyl) benzene. This reaction uses light to homogenize chlorine gas to produce chlorine radicals, which are then substituted with hydrogen atoms on the p-chlorotoluene methyl group. The reaction conditions are relatively mild, and the equipment requirements are not high, but attention should be paid to control the degree of reaction to avoid the formation of polychlorinated by-products. Due to its wide source of raw materials p-chlorotoluene and moderate price, this method is widely used.
2. ** Using benzene as the starting material **: Benzene is first alkylated with chloromethyl chloride under the catalysis of Lewis acid (such as aluminum trichloride) to form p-chloromethylbenzene; after that, p-chloromethylbenzene and chlorine are introduced into the ortho-position of the benzene ring under the action of light or initiator to obtain 1% 2C2-dichloro-4- (chloromethyl) benzene. This route has a little more steps, but the raw material benzene is inexpensive, and the reaction selectivity of each step is good, so the yield can be improved by optimizing the reaction conditions. However, the Fu-gram alkylation reaction requires an anhydrous environment and the use of corrosive Lewis acid, which requires strict operation.
3. ** Using p-dichlorobenzene as raw material **: The chloromethylation reaction of p-dichlorobenzene with formaldehyde and hydrogen chloride occurs in the presence of a specific catalyst (such as zinc salt, etc.), directly generating 1% 2C2 -dichloro-4- (chloromethyl) benzene. This reaction has good atomic economy and theoretically high utilization of raw materials. However, the reaction conditions are more demanding, requiring high catalyst activity and selectivity, and parameters such as reaction temperature, pressure, and raw material ratio need to be precisely controlled to ensure the yield and purity of the target product.
What are the effects of 1,2-dichloro-4- (chloromethyl) benzene on the environment and humans?
1% 2C2-dichloro-4- (chloromethyl) benzene, this substance is an organic compound. Its impact on the environment and human body, let me discuss in detail.
At the environmental level, this compound has a certain persistence. If released into the soil, due to its hydrophobicity, it is difficult to dissolve in water, or adsorbed on soil particles, and persists for a long time, hindering the normal activities of microorganisms in the soil, interfering with the material cycle and energy conversion of the soil ecosystem. If it flows into the water body, it will accumulate in aquatic organisms, pass through the food chain, and amplify, threatening the balance of the entire aquatic ecosystem and reducing biodiversity. And it evaporates into the atmosphere, which will participate in photochemical reactions and have a negative impact on the atmospheric environment.
As for the impact on the human body, first of all, it is irritating. If skin contact, it can cause skin redness, itching, pain, and in severe cases, blisters and ulcers. Eye contact can irritate the eyes, causing symptoms such as eye pain, tears, and blurred vision. Inhalation of its volatile gases can irritate the respiratory tract, causing cough, asthma, breathing difficulties, and long-term exposure or increase the risk of respiratory diseases. More importantly, this compound may have potential carcinogenicity. Although the exact carcinogenic mechanism is not fully understood, studies have shown that long-term exposure to compounds containing such structures can increase the probability of human cells becoming cancerous, posing a serious threat to life and health. Therefore, the use, production and emission of such compounds need to be strictly controlled to reduce their harm to the environment and people.
At the environmental level, this compound has a certain persistence. If released into the soil, due to its hydrophobicity, it is difficult to dissolve in water, or adsorbed on soil particles, and persists for a long time, hindering the normal activities of microorganisms in the soil, interfering with the material cycle and energy conversion of the soil ecosystem. If it flows into the water body, it will accumulate in aquatic organisms, pass through the food chain, and amplify, threatening the balance of the entire aquatic ecosystem and reducing biodiversity. And it evaporates into the atmosphere, which will participate in photochemical reactions and have a negative impact on the atmospheric environment.
As for the impact on the human body, first of all, it is irritating. If skin contact, it can cause skin redness, itching, pain, and in severe cases, blisters and ulcers. Eye contact can irritate the eyes, causing symptoms such as eye pain, tears, and blurred vision. Inhalation of its volatile gases can irritate the respiratory tract, causing cough, asthma, breathing difficulties, and long-term exposure or increase the risk of respiratory diseases. More importantly, this compound may have potential carcinogenicity. Although the exact carcinogenic mechanism is not fully understood, studies have shown that long-term exposure to compounds containing such structures can increase the probability of human cells becoming cancerous, posing a serious threat to life and health. Therefore, the use, production and emission of such compounds need to be strictly controlled to reduce their harm to the environment and people.
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