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1,2-Dichloro-4-Fluoro-5-Nitrobenzene
Linshang Chemical
|
HS Code |
549385 |
| Chemical Formula | C6H2Cl2FNO2 |
| Molar Mass | 209.99 g/mol |
| Appearance | Solid (usually a yellow - colored solid) |
| Melting Point | 72 - 74 °C |
| Boiling Point | 267 - 268 °C |
| Density | 1.64 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Flash Point | 115 °C |
| Vapor Pressure | Low vapor pressure at room temperature |
As an accredited 1,2-Dichloro-4-Fluoro-5-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250 - gram bottle packaging for 1,2 - dichloro - 4 - fluoro - 5 - nitrobenzene chemical. |
| Storage | 1,2 - Dichloro - 4 - fluoro - 5 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent leakage. It is best stored in a dedicated chemical storage cabinet, clearly labeled to avoid confusion, and in accordance with local safety regulations. |
| Shipping | 1,2 - dichloro - 4 - fluoro - 5 - nitrobenzene, a hazardous chemical, is shipped in tightly sealed, corrosion - resistant containers. Specialized carriers follow strict regulations for safe transportation to prevent spills and ensure environmental and public safety. |
Competitive 1,2-Dichloro-4-Fluoro-5-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1,2-Dichloro-4-Fluoro-5-Nitrobenzene in China?
As a trusted 1,2-Dichloro-4-Fluoro-5-Nitrobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1,2-Dichloro-4-Fluoro-5-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1,2-dichloro-4-fluoro-5-nitrobenzene?
1% 2C2-dideuterium-4-ene-5-carboxybenzene has a variety of important uses in different fields.
In the field of medicinal chemistry, its unique chemical structure makes it a key intermediate for the synthesis of specific drugs. By modifying and modifying the structure of this compound, drug molecules with specific pharmacological activities can be prepared. For example, for some specific disease targets, the development of therapeutic drugs that are compatible with it. Introducing other functional groups through chemical synthesis can optimize the key properties such as solubility, stability and bioavailability of drug molecules, laying the foundation for the development of new drugs.
In the field of materials science, this compound may participate in the synthesis of functional materials. Due to its structural properties, it is possible to endow materials with unique optoelectronic properties. For example, it is used to prepare organic semiconductor materials, which are used in optoelectronic devices such as organic Light Emitting Diodes (OLEDs) and organic solar cells. With its active check points such as double bonds and carboxyl groups in its structure, it can be combined or cross-linked with other materials to improve the mechanical properties and stability of the material, and meet the needs of different material application scenarios.
In organic synthetic chemistry, 1% 2C2-dideuterium-4-ene-5-carboxylbenzene is used as an important synthetic building block for the construction of more complex organic molecular structures. Organic chemists can use their double bonds and carboxyl groups to carry out a variety of chemical reactions, such as the addition reaction of olefins, the esterification reaction of carboxyl groups, etc. With the help of these reactions, a series of organic compounds with novel structures and potential application value can be synthesized, which enriches the library of organic compounds and provides raw materials and possibilities for further research and development of new substances.
In the field of medicinal chemistry, its unique chemical structure makes it a key intermediate for the synthesis of specific drugs. By modifying and modifying the structure of this compound, drug molecules with specific pharmacological activities can be prepared. For example, for some specific disease targets, the development of therapeutic drugs that are compatible with it. Introducing other functional groups through chemical synthesis can optimize the key properties such as solubility, stability and bioavailability of drug molecules, laying the foundation for the development of new drugs.
In the field of materials science, this compound may participate in the synthesis of functional materials. Due to its structural properties, it is possible to endow materials with unique optoelectronic properties. For example, it is used to prepare organic semiconductor materials, which are used in optoelectronic devices such as organic Light Emitting Diodes (OLEDs) and organic solar cells. With its active check points such as double bonds and carboxyl groups in its structure, it can be combined or cross-linked with other materials to improve the mechanical properties and stability of the material, and meet the needs of different material application scenarios.
In organic synthetic chemistry, 1% 2C2-dideuterium-4-ene-5-carboxylbenzene is used as an important synthetic building block for the construction of more complex organic molecular structures. Organic chemists can use their double bonds and carboxyl groups to carry out a variety of chemical reactions, such as the addition reaction of olefins, the esterification reaction of carboxyl groups, etc. With the help of these reactions, a series of organic compounds with novel structures and potential application value can be synthesized, which enriches the library of organic compounds and provides raw materials and possibilities for further research and development of new substances.
What are the physical properties of 1,2-dichloro-4-fluoro-5-nitrobenzene?
1% 2C2-dioxy-4-ene-5-carboxylbenzene is a chemical substance that has not yet been recognized in the era of Tiangong Kaiwu. This compound has unique physical properties.
In terms of appearance, it is often white to light yellow crystalline powder with delicate texture. When viewed in sunlight, it has a slight luster and flickering, just like the shimmer of fine stars gathered in one place.
Its melting point is in a specific range, about [X] ° C. When heated to this point, the substance gradually melts from solid to liquid. This process is smooth and continuous, just like ice and snow quietly melting under the warm sun in spring.
Solubility is quite critical. In organic solvents, such as ethanol, acetone, etc., it shows good solubility, just like salt is integrated into water, and it quickly disperses evenly; however, in water, the solubility is extremely low, just like oil drops in water, and it is difficult to blend.
In terms of stability, it can remain relatively stable in a normal temperature and pressure environment protected from light, just like a stable thing in a quiet place, which is not easy to change. However, in the case of strong acids, strong bases or high temperature environments, chemical reactions are prone to occur, and the structure changes. In case of strong winds and rains, the original orderly state is suddenly destroyed.
Its density is also different from that of water, which is about [X] g/cm ³. When placed in water, it will sink or float according to its density characteristics, just like stone and wood entering water, each with its own state.
Although this substance is not included in "Tiangong Kaiwu", from today's chemical perspective, its physical properties determine its use and reactivity, and it is of potential significance in chemical, pharmaceutical and other fields.
In terms of appearance, it is often white to light yellow crystalline powder with delicate texture. When viewed in sunlight, it has a slight luster and flickering, just like the shimmer of fine stars gathered in one place.
Its melting point is in a specific range, about [X] ° C. When heated to this point, the substance gradually melts from solid to liquid. This process is smooth and continuous, just like ice and snow quietly melting under the warm sun in spring.
Solubility is quite critical. In organic solvents, such as ethanol, acetone, etc., it shows good solubility, just like salt is integrated into water, and it quickly disperses evenly; however, in water, the solubility is extremely low, just like oil drops in water, and it is difficult to blend.
In terms of stability, it can remain relatively stable in a normal temperature and pressure environment protected from light, just like a stable thing in a quiet place, which is not easy to change. However, in the case of strong acids, strong bases or high temperature environments, chemical reactions are prone to occur, and the structure changes. In case of strong winds and rains, the original orderly state is suddenly destroyed.
Its density is also different from that of water, which is about [X] g/cm ³. When placed in water, it will sink or float according to its density characteristics, just like stone and wood entering water, each with its own state.
Although this substance is not included in "Tiangong Kaiwu", from today's chemical perspective, its physical properties determine its use and reactivity, and it is of potential significance in chemical, pharmaceutical and other fields.
Is the chemical properties of 1,2-dichloro-4-fluoro-5-nitrobenzene stable?
1% 2C2-dichloro-4-ethylene-5-fluorobenzene. The chemical properties of this substance are relatively stable.
Structurally, chlorine atoms and fluorine atoms in its molecules are connected to the benzene ring. Chlorine atoms and fluorine atoms will affect the electron cloud distribution of the benzene ring due to their large electronegativity, which reduces the electron cloud density on the benzene ring. This change in the electron cloud distribution makes it relatively difficult for the benzene ring to carry out electrophilic substitution reactions. For example, the activity of electrophilic substitution reactions such as halogenation, nitrification, and sulfonation will decrease, thus increasing its chemical stability to a certain extent.
At the same time, carbon-chlorine bonds and carbon-fluorine bonds have high bond energies. The bond energy of the carbon-chlorine bond makes it difficult for the chlorine atom to break away from the molecule. The bond energy of the carbon-fluorine bond is higher, and the fluorine atom is more difficult to be replaced or undergo other reactions. The existence of these two strong bonds acts as a strong barrier, hindering the destruction of the molecular structure by external reagents, further enhancing the stability of the substance.
In addition, the symmetry of the molecular structure also contributes to its stability. This symmetry makes the interaction between molecules relatively regular, and the molecule is not prone to structural rearrangement or reaction due to weak external interference. Therefore, under common conditions, 1% 2C2-dichloro-4-ethylene-5-fluorobenzene can maintain relatively stable chemical properties.
Structurally, chlorine atoms and fluorine atoms in its molecules are connected to the benzene ring. Chlorine atoms and fluorine atoms will affect the electron cloud distribution of the benzene ring due to their large electronegativity, which reduces the electron cloud density on the benzene ring. This change in the electron cloud distribution makes it relatively difficult for the benzene ring to carry out electrophilic substitution reactions. For example, the activity of electrophilic substitution reactions such as halogenation, nitrification, and sulfonation will decrease, thus increasing its chemical stability to a certain extent.
At the same time, carbon-chlorine bonds and carbon-fluorine bonds have high bond energies. The bond energy of the carbon-chlorine bond makes it difficult for the chlorine atom to break away from the molecule. The bond energy of the carbon-fluorine bond is higher, and the fluorine atom is more difficult to be replaced or undergo other reactions. The existence of these two strong bonds acts as a strong barrier, hindering the destruction of the molecular structure by external reagents, further enhancing the stability of the substance.
In addition, the symmetry of the molecular structure also contributes to its stability. This symmetry makes the interaction between molecules relatively regular, and the molecule is not prone to structural rearrangement or reaction due to weak external interference. Therefore, under common conditions, 1% 2C2-dichloro-4-ethylene-5-fluorobenzene can maintain relatively stable chemical properties.
What are the synthesis methods of 1,2-dichloro-4-fluoro-5-nitrobenzene?
The synthesis method of 1% 2C2-dibromo-4-ethylene-5-cyanobenzene, through the ages, many parties have their own wonderful methods, and now I will describe them in detail.
One of them can be started from benzene derivatives. First take benzene containing an appropriate substituent, and introduce bromine atoms through halogenation reaction. This halogenation reaction requires a suitable halogenating agent, such as bromine and a suitable catalyst, to control the reaction conditions. Temperature and time need to be precisely controlled, so that bromine atoms are connected to the benzene ring at the expected position to obtain bromine-containing benzene derivatives. Then, the introduction of vinyl can be achieved through nucleophilic substitution or coupling reaction. In the case of nucleophilic substitution, select a vinyl reagent with suitable activity and react with a suitable solvent in the presence of a base; in the coupling reaction, a specific catalyst and ligand need to be selected to promote the formation of carbon-carbon bonds and connect vinyl groups. Finally, a cyanyl group is introduced, and a halogen and cyanide are often used for nucleophilic substitution. The selection of cyanide and the regulation of the reaction environment are related to success or failure.
Second, it is modified with a compound with a similar structure. If a compound containing part of the target structure is found, its specific group can be modified and converted. If it contains a similar phenyl ring and has a convertible group, the convertible group is activated first, and bromine, vinyl and cyanyl are gradually introduced through the functional group conversion reaction. This process requires familiarity with the reaction characteristics of various functional groups, rational planning of the reaction sequence, and avoidance of unnecessary side reactions.
Third, with the help of multi-step tandem reactions. Design a series of coherent reactions, so that the starting materials are converted into target molecules in the same reaction system or in successive steps through ingenious intermediates. This strategy requires a thorough understanding of the reaction mechanism and careful design of reaction conditions to ensure the smooth connection of each step of the reaction, and the efficient synthesis of 1% 2C2-dibromo-4-ethylene-5-cyanobenzene.
The above methods have their own advantages and disadvantages. In practical application, when considering factors such as raw material availability, cost, reaction difficulty and yield, make a prudent choice.
One of them can be started from benzene derivatives. First take benzene containing an appropriate substituent, and introduce bromine atoms through halogenation reaction. This halogenation reaction requires a suitable halogenating agent, such as bromine and a suitable catalyst, to control the reaction conditions. Temperature and time need to be precisely controlled, so that bromine atoms are connected to the benzene ring at the expected position to obtain bromine-containing benzene derivatives. Then, the introduction of vinyl can be achieved through nucleophilic substitution or coupling reaction. In the case of nucleophilic substitution, select a vinyl reagent with suitable activity and react with a suitable solvent in the presence of a base; in the coupling reaction, a specific catalyst and ligand need to be selected to promote the formation of carbon-carbon bonds and connect vinyl groups. Finally, a cyanyl group is introduced, and a halogen and cyanide are often used for nucleophilic substitution. The selection of cyanide and the regulation of the reaction environment are related to success or failure.
Second, it is modified with a compound with a similar structure. If a compound containing part of the target structure is found, its specific group can be modified and converted. If it contains a similar phenyl ring and has a convertible group, the convertible group is activated first, and bromine, vinyl and cyanyl are gradually introduced through the functional group conversion reaction. This process requires familiarity with the reaction characteristics of various functional groups, rational planning of the reaction sequence, and avoidance of unnecessary side reactions.
Third, with the help of multi-step tandem reactions. Design a series of coherent reactions, so that the starting materials are converted into target molecules in the same reaction system or in successive steps through ingenious intermediates. This strategy requires a thorough understanding of the reaction mechanism and careful design of reaction conditions to ensure the smooth connection of each step of the reaction, and the efficient synthesis of 1% 2C2-dibromo-4-ethylene-5-cyanobenzene.
The above methods have their own advantages and disadvantages. In practical application, when considering factors such as raw material availability, cost, reaction difficulty and yield, make a prudent choice.
What are the precautions for storing and transporting 1,2-dichloro-4-fluoro-5-nitrobenzene?
1% 2C2-dioxo-4-ene-5-carboxylnaphthalene is also a chemical substance. During storage and transportation, many matters need to be paid attention to.
First, when storing, it should be placed in a cool, dry and well-ventilated place. This material may be afraid of moisture and heat. If the environment is humid and warm, it may cause it to deteriorate and damage its chemical properties. As "Tiangong Kaiwu" says, when storing things, you should observe their properties and let them be, and the same is true.
Second, it should be stored separately from oxidants, acids, bases, etc. Because of its chemical activity, if it coexists with them, or reacts violently, it will be dangerous to life. For example, when "Tiangong Kaiwu" talks about the compatibility of various things, it is necessary to carefully examine their properties to prevent them from attacking each other, especially this chemical substance.
Third, during transportation, make sure that the container is sealed. If there is a leak, it will not only damage the substance, but also endanger the transporter and the surrounding environment. It needs to be transported with special equipment and suitable packaging, and it should be carried out in accordance with relevant laws and regulations. For example, the transportation laws in "Tiangong Kaiwu" must be strictly observed to ensure safety.
Fourth, the operator should be equipped with protective equipment. Because it may be toxic and corrosive to a certain extent, direct contact will be harmful to the body. This protective measure, such as the labor of ancient craftsmen, is also known to protect the body from its harm.
In conclusion, the storage and transportation of 1% 2C2-dioxy-4-ene-5-carboxylnaphthalene requires caution, physical inspection, and compliance with regulations to ensure safety.
First, when storing, it should be placed in a cool, dry and well-ventilated place. This material may be afraid of moisture and heat. If the environment is humid and warm, it may cause it to deteriorate and damage its chemical properties. As "Tiangong Kaiwu" says, when storing things, you should observe their properties and let them be, and the same is true.
Second, it should be stored separately from oxidants, acids, bases, etc. Because of its chemical activity, if it coexists with them, or reacts violently, it will be dangerous to life. For example, when "Tiangong Kaiwu" talks about the compatibility of various things, it is necessary to carefully examine their properties to prevent them from attacking each other, especially this chemical substance.
Third, during transportation, make sure that the container is sealed. If there is a leak, it will not only damage the substance, but also endanger the transporter and the surrounding environment. It needs to be transported with special equipment and suitable packaging, and it should be carried out in accordance with relevant laws and regulations. For example, the transportation laws in "Tiangong Kaiwu" must be strictly observed to ensure safety.
Fourth, the operator should be equipped with protective equipment. Because it may be toxic and corrosive to a certain extent, direct contact will be harmful to the body. This protective measure, such as the labor of ancient craftsmen, is also known to protect the body from its harm.
In conclusion, the storage and transportation of 1% 2C2-dioxy-4-ene-5-carboxylnaphthalene requires caution, physical inspection, and compliance with regulations to ensure safety.
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