Linshang Chemical
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1,2-Dichloro-4-Methyl-3-Nitro-5-(Trifluoromethyl)Benzene
Linshang Chemical
|
HS Code |
565030 |
| Chemical Formula | C7H3Cl2F3NO2 |
| Molar Mass | 260.003 g/mol |
| Appearance | Solid (likely, based on similar compounds) |
| Physical State At Room Temp | Solid |
| Solubility In Water | Low (due to non - polar nature of the molecule with hydrophobic groups) |
| Solubility In Organic Solvents | Moderate to high in non - polar and some polar organic solvents |
| Vapor Pressure | Low at room temperature |
As an accredited 1,2-Dichloro-4-Methyl-3-Nitro-5-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 1,2 - dichloro - 4 - methyl - 3 - nitro - 5 - (trifluoromethyl)benzene in sealed chemical - grade bottle. |
| Storage | 1,2 - Dichloro - 4 - methyl - 3 - nitro - 5 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from sources of heat, ignition, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials, to prevent leakage and exposure to air or moisture. |
| Shipping | 1,2 - Dichloro - 4 - methyl - 3 - nitro - 5 - (trifluoromethyl)benzene is shipped in specialized, well - sealed containers compliant with chemical transport regulations. Handling during shipping ensures protection from physical damage and environmental exposure. |
Competitive 1,2-Dichloro-4-Methyl-3-Nitro-5-(Trifluoromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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Where to Buy 1,2-Dichloro-4-Methyl-3-Nitro-5-(Trifluoromethyl)Benzene in China?
As a trusted 1,2-Dichloro-4-Methyl-3-Nitro-5-(Trifluoromethyl)Benzene manufacturer, we deliver:
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As a leading 1,2-Dichloro-4-Methyl-3-Nitro-5-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1,2-dichloro-4-methyl-3-nitro-5- (trifluoromethyl) benzene?
1% 2C2-dichloro-4-methyl-3-nitro-5- (trifluoromethyl) benzene is widely used. In the field of pharmaceutical synthesis, it is often used as a key intermediate, which can be converted into pharmaceutical ingredients with specific pharmacological activities through a series of chemical reactions. For example, when developing some antibacterial and anti-tumor drugs, it has a special chemical structure that can precisely interact with target biomolecules, providing the possibility for the creation of new drugs with high efficiency and low toxicity.
In the field of pesticides, it is also an important synthetic raw material. The synthetic pesticides have high selective inhibition and killing ability to specific pests and weeds, and can be well integrated into the environment, with low residues and reduced negative impact on ecology. Like the preparation of some new pesticides and herbicides, it will be used to effectively protect crop growth, improve yield and quality.
In addition, it also has a place in the field of materials science. It can be used to prepare polymer materials with special properties, such as some materials with high resistance to chemical corrosion and ultraviolet radiation. It is widely used in construction, electronics and other industries to enhance the service life and stability of materials.
Its unique chemical structure and properties make it play an indispensable role in the synthesis of many fine chemical products and provide important support for the development of related industries.
In the field of pesticides, it is also an important synthetic raw material. The synthetic pesticides have high selective inhibition and killing ability to specific pests and weeds, and can be well integrated into the environment, with low residues and reduced negative impact on ecology. Like the preparation of some new pesticides and herbicides, it will be used to effectively protect crop growth, improve yield and quality.
In addition, it also has a place in the field of materials science. It can be used to prepare polymer materials with special properties, such as some materials with high resistance to chemical corrosion and ultraviolet radiation. It is widely used in construction, electronics and other industries to enhance the service life and stability of materials.
Its unique chemical structure and properties make it play an indispensable role in the synthesis of many fine chemical products and provide important support for the development of related industries.
What are the physical properties of 1,2-dichloro-4-methyl-3-nitro-5- (trifluoromethyl) benzene?
1% 2C2-dibromo-4-methyl-3-furyl-5- (trifluoromethyl) benzene, this substance is an organic compound, and its physical properties are crucial to its application in many fields.
First of all, looking at its properties, under normal conditions, it is mostly in a solid state. Due to the strong force between molecules, it exists stably in a solid state at room temperature and pressure. This property is of great significance in storage and transportation. Compared with liquid or gaseous substances, solid states are easier to preserve and transport.
Furthermore, melting point is an important physical parameter. Generally speaking, the melting point of this substance is relatively high, which is due to its complex molecular structure and strong intermolecular forces. A higher melting point indicates that more energy is required to break the intermolecular bonds and transform it from a solid state to a liquid state. This property has a significant impact in the field of material processing. If it needs to be melted, it is necessary to consider providing enough heat to reach the melting point.
The boiling point is also a key property. Because its molecular structure contains halogen atoms and other groups, the intermolecular forces are further enhanced, so the boiling point is also high. This means that when heating to vaporize it, a lot of energy is required. In chemical production, this property of boiling point becomes an important consideration when it comes to operations such as distillation and separation of the substance.
In terms of solubility, because of its hydrophobic groups, the solubility in water is low. However, in some organic solvents such as dichloromethane, chloroform, etc., it has good solubility. This property is crucial in the organic synthesis process, and a suitable solvent can be selected for the reaction, so as to better dissolve the reactants and promote the smooth progress of the reaction.
In addition, density is also one of its physical properties. Due to the large relative atomic weight of bromine atoms and fluorine atoms in the molecule, the density of this substance is higher than that of common organic compounds. This needs to be taken into account when it comes to operations such as separation and mixing of substances.
The above are the main physical properties of 1% 2C2-dibromo-4-methyl-3-furyl-5- (trifluoromethyl) benzene, which are interrelated and together affect the performance of the substance in practical applications.
First of all, looking at its properties, under normal conditions, it is mostly in a solid state. Due to the strong force between molecules, it exists stably in a solid state at room temperature and pressure. This property is of great significance in storage and transportation. Compared with liquid or gaseous substances, solid states are easier to preserve and transport.
Furthermore, melting point is an important physical parameter. Generally speaking, the melting point of this substance is relatively high, which is due to its complex molecular structure and strong intermolecular forces. A higher melting point indicates that more energy is required to break the intermolecular bonds and transform it from a solid state to a liquid state. This property has a significant impact in the field of material processing. If it needs to be melted, it is necessary to consider providing enough heat to reach the melting point.
The boiling point is also a key property. Because its molecular structure contains halogen atoms and other groups, the intermolecular forces are further enhanced, so the boiling point is also high. This means that when heating to vaporize it, a lot of energy is required. In chemical production, this property of boiling point becomes an important consideration when it comes to operations such as distillation and separation of the substance.
In terms of solubility, because of its hydrophobic groups, the solubility in water is low. However, in some organic solvents such as dichloromethane, chloroform, etc., it has good solubility. This property is crucial in the organic synthesis process, and a suitable solvent can be selected for the reaction, so as to better dissolve the reactants and promote the smooth progress of the reaction.
In addition, density is also one of its physical properties. Due to the large relative atomic weight of bromine atoms and fluorine atoms in the molecule, the density of this substance is higher than that of common organic compounds. This needs to be taken into account when it comes to operations such as separation and mixing of substances.
The above are the main physical properties of 1% 2C2-dibromo-4-methyl-3-furyl-5- (trifluoromethyl) benzene, which are interrelated and together affect the performance of the substance in practical applications.
Is 1,2-dichloro-4-methyl-3-nitro-5- (trifluoromethyl) benzene chemically stable?
1% 2C2-dibromo-4-methyl-3-furyl-5 - (trifluoromethyl) pyridine The chemical properties of this compound are relatively stable.
From its structure, the molecule contains bromine atoms, which have a certain electronegativity, which will affect the electron cloud distribution of the molecule, so that in some reactions, bromine atoms can participate in nucleophilic substitution as leaving groups. However, at the same time, the presence of pyridine rings and furan groups makes the whole molecule have a certain aromaticity, and the aromatic system usually has good stability. The introduction of methyl and trifluoromethyl changed the electronic and spatial effects of the molecule. Trifluoromethyl has strong electron absorption, which will reduce the electron cloud density of the carbon atoms connected to it, thereby affecting the reactivity check point of the whole molecule. And methyl is a power supply group, which will increase the electron cloud density at the connected position.
Due to the large conjugation system of pyridine ring and furan group, the degree of π electron delocalization of the molecule is high, which also enhances the stability of the molecule to a certain extent. And this conjugation system will also affect the spectral properties of the molecule.
Overall, the compound can maintain a relatively stable state under general conditions, but under specific reaction conditions, such as strong nucleophiles, high temperatures, etc., some of its functional groups will undergo corresponding chemical reactions.
From its structure, the molecule contains bromine atoms, which have a certain electronegativity, which will affect the electron cloud distribution of the molecule, so that in some reactions, bromine atoms can participate in nucleophilic substitution as leaving groups. However, at the same time, the presence of pyridine rings and furan groups makes the whole molecule have a certain aromaticity, and the aromatic system usually has good stability. The introduction of methyl and trifluoromethyl changed the electronic and spatial effects of the molecule. Trifluoromethyl has strong electron absorption, which will reduce the electron cloud density of the carbon atoms connected to it, thereby affecting the reactivity check point of the whole molecule. And methyl is a power supply group, which will increase the electron cloud density at the connected position.
Due to the large conjugation system of pyridine ring and furan group, the degree of π electron delocalization of the molecule is high, which also enhances the stability of the molecule to a certain extent. And this conjugation system will also affect the spectral properties of the molecule.
Overall, the compound can maintain a relatively stable state under general conditions, but under specific reaction conditions, such as strong nucleophiles, high temperatures, etc., some of its functional groups will undergo corresponding chemical reactions.
What are the synthesis methods of 1,2-dichloro-4-methyl-3-nitro-5- (trifluoromethyl) benzene?
The method for synthesizing 1% 2C2-dichloro-4-methyl-3-furan-5- (trichloromethyl) pyridine is as follows:
The first method of nucleophilic substitution. In this method, a pyridine derivative containing a suitable substituent can be met with a halogenated reagent. For example, a pyridine with a specific substituent is used as a substrate to react with a dichloro reagent in a suitable solvent, such as dichloromethane, N, N-dimethylformamide, under the catalysis of a base. The alkali can be selected from potassium carbonate, sodium carbonate, etc. The reaction temperature depends on the activity of the substrate and the reagent, or at room temperature, or needs to be heated to tens of degrees Celsius. After a few hours or even more, the halogen atom can nucleophilically replace the specific hydrogen atom on the pyridine ring, so as to obtain a part of the structure of the target product.
Furthermore, the cyclization reaction path can be considered. First prepare a precursor with a potential cyclization structure, such as a chain-like compound containing unsaturated bonds such as alkenyl groups and alkynyl groups with appropriate substituents. Make this precursor undergo intramolecular cyclization under the action of a suitable catalyst. If the precursor contains alkenyl groups and haloalkyl groups, the cyclization reaction can be initiated under the catalysis of transition metal catalysts such as palladium catalysts, and specific substituents can be introduced while constructing the pyridine ring. Factors such as the amount of catalyst and the polarity of the reaction solvent have a great influence on the reaction and must be carefully regulated.
can be achieved through multi-step reaction combinations. First, a pyridine intermediate containing some target substituents is prepared by a conventional organic reaction, such as the introduction of methyl and other substituents by Friedel-Crafts reaction. Then, chlorine atoms are introduced at specific positions in the pyridine ring through halogenation reactions, such as the use of chlorine gas, hydrogen halide and other halogenating reagents. After each step of the reaction, the product needs to be purified by recrystallization, column chromatography, etc., to ensure the smooth progress of the next step of the reaction. After carefully designing and implementing the reaction in multiple steps, 1% 2C2-dichloro-4-methyl-3-furan-5- (trichloromethyl) pyridine is finally synthesized.
The first method of nucleophilic substitution. In this method, a pyridine derivative containing a suitable substituent can be met with a halogenated reagent. For example, a pyridine with a specific substituent is used as a substrate to react with a dichloro reagent in a suitable solvent, such as dichloromethane, N, N-dimethylformamide, under the catalysis of a base. The alkali can be selected from potassium carbonate, sodium carbonate, etc. The reaction temperature depends on the activity of the substrate and the reagent, or at room temperature, or needs to be heated to tens of degrees Celsius. After a few hours or even more, the halogen atom can nucleophilically replace the specific hydrogen atom on the pyridine ring, so as to obtain a part of the structure of the target product.
Furthermore, the cyclization reaction path can be considered. First prepare a precursor with a potential cyclization structure, such as a chain-like compound containing unsaturated bonds such as alkenyl groups and alkynyl groups with appropriate substituents. Make this precursor undergo intramolecular cyclization under the action of a suitable catalyst. If the precursor contains alkenyl groups and haloalkyl groups, the cyclization reaction can be initiated under the catalysis of transition metal catalysts such as palladium catalysts, and specific substituents can be introduced while constructing the pyridine ring. Factors such as the amount of catalyst and the polarity of the reaction solvent have a great influence on the reaction and must be carefully regulated.
can be achieved through multi-step reaction combinations. First, a pyridine intermediate containing some target substituents is prepared by a conventional organic reaction, such as the introduction of methyl and other substituents by Friedel-Crafts reaction. Then, chlorine atoms are introduced at specific positions in the pyridine ring through halogenation reactions, such as the use of chlorine gas, hydrogen halide and other halogenating reagents. After each step of the reaction, the product needs to be purified by recrystallization, column chromatography, etc., to ensure the smooth progress of the next step of the reaction. After carefully designing and implementing the reaction in multiple steps, 1% 2C2-dichloro-4-methyl-3-furan-5- (trichloromethyl) pyridine is finally synthesized.
What are the precautions for storing and transporting 1,2-dichloro-4-methyl-3-nitro-5- (trifluoromethyl) benzene?
1% 2C2-dichloro-4-methyl-3-furan-5- (trichloromethyl) benzene, when storing and transporting, there are several points to pay attention to.
The first is related to safety protection. This is a chemical substance and is potentially dangerous. When storing, make sure that the storage place is well ventilated and away from fire and heat sources. Because of its flammability, toxicity and other characteristics, in case of open flame or hot topic, it may cause fire and explosion, endangering people and things around. When transporting, transporters also need to be fully armed, wearing protective clothing, protective gloves and goggles, etc., to prevent physical damage caused by contact with this substance.
The second is the importance of packaging. Stable and tight packaging is required for storage and transportation. Improper packaging, substances or leakage, pollute the environment, and also pose a threat to the health of surrounding personnel. Packaging materials should be resistant to chemical corrosion and can resist certain external impacts to ensure that the packaging is not damaged during routine handling and turbulence.
Furthermore, the identification is clear. On storage containers and transportation vehicles, there should be prominent labels indicating the name, nature, hazard and emergency treatment methods of this object. This allows relevant personnel to quickly know its characteristics when they come into contact. In the event of an emergency, appropriate emergency measures can be taken according to the signs.
In addition, storage conditions should not be underestimated. When controlling the temperature and humidity of the storage environment according to the characteristics of the substance. Some chemical substances are prone to chemical reactions, deterioration or danger in high temperature and high humidity environments. It needs to be stored according to the specified conditions to ensure its stability and safety.
During transportation, it is also necessary to strictly abide by transportation regulations. Choose a suitable transportation route to avoid densely populated areas and environmentally sensitive areas. And the transportation process should be monitored in real time to ensure that the material status is normal. If there is any abnormality, it can be dealt with in time.
The first is related to safety protection. This is a chemical substance and is potentially dangerous. When storing, make sure that the storage place is well ventilated and away from fire and heat sources. Because of its flammability, toxicity and other characteristics, in case of open flame or hot topic, it may cause fire and explosion, endangering people and things around. When transporting, transporters also need to be fully armed, wearing protective clothing, protective gloves and goggles, etc., to prevent physical damage caused by contact with this substance.
The second is the importance of packaging. Stable and tight packaging is required for storage and transportation. Improper packaging, substances or leakage, pollute the environment, and also pose a threat to the health of surrounding personnel. Packaging materials should be resistant to chemical corrosion and can resist certain external impacts to ensure that the packaging is not damaged during routine handling and turbulence.
Furthermore, the identification is clear. On storage containers and transportation vehicles, there should be prominent labels indicating the name, nature, hazard and emergency treatment methods of this object. This allows relevant personnel to quickly know its characteristics when they come into contact. In the event of an emergency, appropriate emergency measures can be taken according to the signs.
In addition, storage conditions should not be underestimated. When controlling the temperature and humidity of the storage environment according to the characteristics of the substance. Some chemical substances are prone to chemical reactions, deterioration or danger in high temperature and high humidity environments. It needs to be stored according to the specified conditions to ensure its stability and safety.
During transportation, it is also necessary to strictly abide by transportation regulations. Choose a suitable transportation route to avoid densely populated areas and environmentally sensitive areas. And the transportation process should be monitored in real time to ensure that the material status is normal. If there is any abnormality, it can be dealt with in time.
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