1,2-Dichloro-4-Nitro-5-(Trifluoromethyl)Benzene
Linshang Chemical
HS Code |
781884 |
Chemical Formula | C7H2Cl2F3NO2 |
Molecular Weight | 260.00 |
Appearance | Solid (likely) |
Odor | Unspecified (but may have a pungent or characteristic odor due to functional groups) |
Boiling Point | Unspecified |
Melting Point | Unspecified |
Solubility In Water | Low (due to non - polar benzene ring and hydrophobic groups like trifluoromethyl) |
Solubility In Organic Solvents | Soluble in common organic solvents such as dichloromethane, chloroform (due to non - polar nature) |
Density | Unspecified |
Vapor Pressure | Low (as a solid, but vapor pressure would increase with temperature) |
Stability | Stable under normal conditions, but may react with strong reducing agents, bases etc. due to nitro and chloro groups |
Hazard Class | Toxic (due to nitro and chloro groups, potential health hazards), flammable (organic compound) |
As an accredited 1,2-Dichloro-4-Nitro-5-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 1,2 - Dichloro - 4 - nitro - 5 - (trifluoromethyl)benzene in 1 - kg sealed containers. |
Storage | 1,2 - Dichloro - 4 - nitro - 5 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials, to prevent leakage and exposure to air or moisture, which could potentially cause decomposition or reactivity issues. |
Shipping | 1,2 - Dichloro - 4 - nitro - 5 - (trifluoromethyl)benzene is shipped in specialized containers designed for hazardous chemicals. It adheres to strict regulations, with proper labeling and handling to ensure safe transportation. |
Competitive 1,2-Dichloro-4-Nitro-5-(Trifluoromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 1,2-Dichloro-4-Nitro-5-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
This compound has important uses in many fields. In the field of materials science, it can significantly improve the properties of materials due to its specific functional groups. For example, with its reactivity of hydroxyl groups and dialdehyde groups, it can be used as a cross-linking agent to strengthen the network structure of polymer materials, greatly improve the mechanical strength and stability of materials, and is widely used in the production of plastics, rubber and other products, making products more durable.
In the field of chemical synthesis, it is a very critical intermediate. Triethoxy silicon groups give it unique reaction characteristics, and can synthesize compounds with special structures and properties through a series of chemical reactions. For example, by reacting with active hydrogen-containing compounds to prepare functional silicone compounds, these products are widely used in the field of coatings and adhesives, which can improve the adhesion, weather resistance of coatings, and enhance the bonding strength and flexibility of adhesives.
In the field of biomedicine, due to its certain biocompatibility and modifiability, it may be used for surface modification of biomaterials. Through appropriate modification, the surface of biomaterials can have better cell adhesion, anticoagulation and other characteristics, which has great potential in the preparation of tissue engineering scaffolds and medical apparatus coatings, helping to improve the performance and safety of biomedical materials, and providing new ways and possibilities for the development of biomedicine.
In the field of catalysis, its special structure may make it an effective catalyst or catalyst carrier for certain reactions. By interacting with the reactants with its own functional groups, it promotes the reaction, improves the selectivity and efficiency of the reaction, and promotes the development of chemical production and other fields.
Looking at its appearance, under normal temperature and pressure, it is mostly in the state of colorless to light yellow liquid, with clear quality and no obvious impurities. When reflected by light, it can be seen that its surface luster flows, which seems to contain mysterious power.
When it comes to the boiling point, it is about a specific temperature range. This temperature gives it the characteristic of transforming from liquid to gaseous under certain conditions, so that it can be separated or converted by temperature regulation in some processes. The exact value of its boiling point is determined by many rigorous experiments, which is of great significance to the design of industrial production processes.
Melting point is also one of the key physical properties. When the temperature drops to a certain precise value, the substance will solidify from liquid to solid state. This melting point temperature becomes an important node to define its phase transition. During storage and transportation, it is necessary to reasonably control the ambient temperature to ensure that the substance exists in a suitable state.
Density is also a property that cannot be ignored. Under standard conditions, its density has a specific value. This value is related to the distribution and behavior of the substance in the mixed system. In chemical synthesis, it plays a decisive role in the accurate allocation of the proportion of reactant materials.
In terms of solubility, it exhibits good solubility in specific organic solvents, and can be mutually soluble with some organic solvents in a certain proportion, but has little solubility in water. This property provides a direction for its application in different fields. For example, in organic synthesis reactions, the appropriate reaction medium can be selected according to its solubility to promote the smooth progress of the reaction.
In addition, the vapor pressure of the substance also changes at different temperatures. This parameter has important guiding significance for operations involving gas phase processes, such as distillation and volatilization. Knowing the law of its vapor pressure change can better control the reaction conditions and achieve efficient production and application.
The above physical properties are interrelated and together outline the unique physical characteristics of 1% 2C2-dioxy-4-cyano-5- (trifluoromethyl) pyridine, which lays a solid foundation for its application in chemical, materials and other fields.
This is an organic compound, and its chemical properties are quite complex. In 1% 2C2-dioxy-4-carbonyl-5 - (trifluoromethyl) pyridine, the dioxy group has certain oxidation properties, or can participate in the oxidation reaction under specific conditions. The presence of carbonyl groups makes the compound capable of reactions such as nucleophilic addition, because its carbonyl carbon has a certain positive electricity and is vulnerable to nucleophilic reagents.
And trifluoromethyl is a strong electron-withdrawing group, which will greatly affect the distribution of molecular electron clouds. Under this influence, the electron cloud density of the pyridine ring decreases, which decreases the electrophilic substitution activity, but increases the nucleophilic substitution activity. At the same time, the strong electron-absorbing effect of trifluoromethyl may increase the acidity of the compound.
As for the amino group, as an electron-supplying group, it can increase the electron cloud density of the pyridine ring, which is the opposite of the effect of trifluoromethyl. Amino groups can participate in many reactions, such as salting with acids, or participating in nucleophilic substitution and condensation under certain conditions.
In summary, 1% 2C2-dioxo-4-carbonyl-5- (trifluoromethyl) pyridine exhibits diverse chemical properties due to the interaction of different functional groups, and may have potential application value in organic synthesis and other fields. According to its characteristics, various chemical reactions can be designed and carried out.
First, benzene is used as the starting material. First, benzene and chlorine are substituted under the action of an appropriate catalyst such as ferric trichloride to obtain chlorobenzene. This reaction requires slow passage of chlorine gas at a suitable temperature and pressure to control the reaction process, so that chlorine is mainly substituted in the para-position of the benzene ring, resulting in a p-chlorobenzene-based product.
Then, the obtained chlorobenzene is heated with a mixed acid (a mixture of nitric acid and sulfuric acid) to carry out a nitrification reaction. Precise temperature control is required. Due to different temperatures, the proportion of isomers in the product is also different. Here, 4-chloro-1-nitrobenzene is obtained.
Then, the system of iron and hydrochloric acid is used to reduce 4-chloro-1-nitrobenzene, and the nitro group is converted into an amino group to obtain 4-chloroaniline.
After that, 4-chloroaniline is reacted with trichloromethylation reagents, such as trichloroacetaldehyde, under appropriate conditions, trichloromethyl can be introduced. In this process, suitable solvents and bases need to be selected to promote the smooth progress of the reaction.
Finally, the obtained product is chlorinated. Under the action of suitable chlorination reagents such as chlorine gas and sulfuryl chloride, chlorine atoms are introduced at specific positions to obtain the target product 1-2-dichloro-4-amino-5- (trichloromethyl) benzene.
Second, another approach can also be found. First, nitrobenzene is obtained by nitrification with benzene as a group, and then nitrobenzene is reduced to aniline. Aniline is co-heated with chloroform and alkali, reacted by Reimer-Tiemann, or trichloromethyl can be introduced, and then chlorinated and nitrified. After multi-step conversion, the target product is also expected. However, this route is a bit complicated, and the reaction conditions of each step also need to be fine-tuned to improve the yield and purity.
For the preparation of this product, the control of the reaction conditions of each step and the trade-off of the amount of reagents are all key. If there is a slight difference, the yield may be low and the product is impure, so caution is required.
First, this substance has specific chemical activities. During operation, it is necessary to abide by the specifications of chemical experiments. For example, you need to wear appropriate protective equipment, including but not limited to laboratory clothes, gloves and goggles, to prevent it from coming into contact with the skin and eyes. If you come into contact, you should immediately rinse with plenty of water and seek medical attention in a timely manner according to the specific situation.
Second, due to the characteristics of its chemical structure, it may be flammable under some conditions. Therefore, the place of use should be kept away from fire and heat sources, and well ventilated to prevent the formation of flammable vapor-air mixtures and reduce the risk of fire and explosion. When storing, it should also be placed in a cool, dry and ventilated place, away from fire and heat sources.
Third, the chemical reactivity of this substance should not be underestimated. Before mixing with other chemical reagents, it is necessary to know in detail the possible reactions between the two. Some reagents are mixed with it, which may cause violent reactions or even generate harmful products. Therefore, before conducting a new reaction, it is advisable to consult relevant information or conduct small-scale pre-experiments.
Fourth, 1% 2C2-dioxy-4-carbonyl-5- (triethoxy) benzyl or potential harm to the environment. Waste generated during use must not be discarded at will, and should be properly disposed of in accordance with local environmental regulations to avoid pollution to soil, water sources and other environmental factors.
Fifth, for the use of this substance, the operator should have the corresponding chemical knowledge and skills, familiar with its nature, use and safety precautions. If it is used for the first time, it should be guided by professional personnel first, and must not be operated blindly.

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