1,2-Dichlorobenzene-D4
Linshang Chemical
HS Code |
481213 |
Chemical Formula | C6D4Cl2 |
Molar Mass | 153.04 g/mol (approximate for D4 - containing compound) |
Appearance | Colorless to light - yellow liquid (similar to non - deuterated 1,2 - dichlorobenzene) |
Boiling Point | 180 - 182 °C (approximate, similar to non - deuterated due to small mass difference from D substitution) |
Melting Point | -17.5 °C (approximate, similar trend as non - deuterated) |
Density | 1.306 g/mL at 20 °C (approximate, similar to non - deuterated) |
Solubility In Water | Insoluble (very low solubility, like non - deuterated 1,2 - dichlorobenzene) |
Solubility In Organic Solvents | Soluble in many organic solvents such as ethanol, ether, benzene |
Vapor Pressure | 1.33 kPa at 47.2 °C (approximate, similar behavior to non - deuterated) |
Odor | Pungent, characteristic aromatic odor (similar to non - deuterated) |
As an accredited 1,2-Dichlorobenzene-D4 factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 1,2 - dichlorobenzene - d4 packaged in a 5 - gram vial for chemical use. |
Storage | 1,2 - Dichlorobenzene - d4 should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of a material resistant to corrosion. Store it separately from oxidizing agents and incompatible substances to prevent reactions. Label the storage container clearly for easy identification. |
Shipping | 1,2 - Dichlorobenzene - d4 is a chemical. Shipping should be in accordance with hazardous material regulations. It must be properly packaged in approved containers to prevent leakage during transit to ensure safety. |
Competitive 1,2-Dichlorobenzene-D4 prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 1,2-Dichlorobenzene-D4 supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
First, in environmental monitoring, it can be an internal standard. Environmental samples are complex in composition, and when detecting various pollutants, 1,2-dichlorobenzene-d4 can be added to the sample. Because the properties of the internal standard are similar to the object to be measured, the instrument's response to it is relevant to the object to be measured. In this way, errors caused by factors such as instrument fluctuations and sample handling losses can be corrected, and the detection accuracy can be improved, making the determination of environmental pollutant content more reliable.
Second, in the development of chemical analysis methods, it is often used as a reference material. When researchers develop new analytical methods, such as gas chromatography-mass spectrometry (GC-MS) and high-performance liquid chromatography (HPLC), for the determination of chlorobenzene-containing compounds, 1,2-dichlorobenzene-d4 is stable in nature and has a clear structure, which can be used as a standard reference. Using it as a benchmark can confirm the accuracy, precision and sensitivity of the analytical method, help to establish a reliable analytical process, and provide an accurate determination basis when unknown samples are analyzed.
Third, it also plays an important role in the study of the reaction mechanism of organic synthesis. Scientists use the unique properties of deuterium-containing compounds to track the reaction process. When 1,2-dichlorobenzene-d4 participates in the organic synthesis reaction, it can be used to detect the whereabouts of deuterium atoms, gain insight into the reaction path, and clarify the way of chemical bond breaking and formation, which provides experimental support for the development of organic synthesis theory and helps to design more efficient and selective organic synthesis routes.
In terms of appearance, 1,2-dichlorobenzene-d4 is usually a colorless to light yellow transparent liquid with a clear appearance and no visible impurities. Its odor has a special aroma, which is slightly similar to that of ordinary 1,2-dichlorobenzene, and has an odor similar to chlorinated aromatics.
In terms of volatility, 1,2-dichlorobenzene-d4 has a certain volatility. At room temperature and pressure, it can slowly dissipate in the air. Its vapor pressure is moderate, and it can be detected when it accumulates to a certain concentration in a closed space.
In terms of solubility, 1,2-dichlorobenzene-d4 is insoluble in water. Due to its non-polar molecular structure and weak interaction with water molecules, its solubility in water is extremely small. However, it is easily soluble in most organic solvents, such as ethanol, ether, acetone, etc., because it can form a similar miscibility with organic solvents.
1,2-dichlorobenzene-d4 has a higher density than water. If it is mixed with water and left to stand, it will sink to the bottom of the water. This property is due to the large mass of chlorine atoms in its molecules, which increases the molecular density.
Melting point and boiling point are also important physical properties. The melting point of 1,2-dichlorobenzene-d4 is about -17 ° C. Below this temperature, the compound changes from liquid to solid. The boiling point is about 180 ° C. When heated to this temperature, 1,2-dichlorobenzene-d4 will change from liquid to gaseous.
In addition, 1,2-dichlorobenzene-d4 has certain stability. Under normal conditions, its chemical properties are relatively stable and chemical reactions are not easy to occur. However, under certain conditions, such as high temperature, light or the presence of catalysts, reactions such as substitution and addition can occur.
Looking at its structure, dichlorobenzene itself is composed of a benzene ring connected to two chlorine atoms, and d4 means that four of the hydrogen atoms are replaced by deuterium atoms. The structure of the benzene ring gives it a certain stability, and the characteristics of aromatic hydrocarbons make it relatively inactive. Although the chlorine atom has a certain electron absorption, because it is conjugated with the benzene ring, the electron cloud distribution is relatively uniform, which further enhances the molecular stability.
In terms of reactivity, under common conditions, reactions such as hydrolysis and oxidation are not easy to occur. When it participates in the reaction, specific catalysts and more harsh reaction conditions are required. For example, in the electrophilic substitution reaction, although the benzene ring has electrophilic activity, the presence of two chlorine atoms reduces the reactivity, and the substitution reaction rate is slower than that of benzene itself.
Again on its physical properties, deuterium atoms replace hydrogen atoms, which slightly increase its relative molecular weight, resulting in a slight difference in physical properties such as melting boiling point from ordinary 1,2-dichlorobenzene. However, from the perspective of chemical stability, this isotope substitution has little effect on the overall stability of the molecule, and the chemical properties are basically the same.
Overall, 1,2-dichlorobenzene-d4 is relatively stable due to its special structure, and can maintain its own chemical state for a long time in normal environments.
Safety is the first priority. This substance is toxic and dangerous. When storing, it must be placed in a cool and well-ventilated place, away from fire and heat sources, to prevent danger. It needs to be stored separately from oxidants and edible chemicals, and must not be mixed to avoid chemical reactions. The storage area should be equipped with suitable containment materials. In case of leakage, it can be dealt with in time.
When transporting, it is also necessary to strictly abide by relevant regulations. Transportation vehicles need to be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. Summer transportation should be selected in the morning and evening to prevent accidents caused by excessive temperature caused by sunlight exposure. During transportation, it is necessary to ensure that the container does not leak, collapse, fall, or be damaged. The loading and unloading personnel need to undergo special training, carry out loading and unloading operations in strict accordance with the operating procedures, and load lightly to avoid violent impact to prevent material leakage due to packaging damage.
In addition, whether it is storage or transportation, it is necessary to do a good job of marking. Clearly label the name of the substance, hazardous characteristics, emergency treatment methods and other information, so that relevant personnel can quickly know its characteristics, and take correct measures in time in case of an accident. Only by strictly treating the storage and transportation links can we effectively avoid hazards and ensure the safety of personnel and the environment.
At one end of the environment, it has a certain volatility, can escape into the atmosphere, diffuse through atmospheric circulation, and cause regional air pollution. If people breathe air containing this pollutant, their health will be damaged. And it is difficult to degrade, enter the soil or water body, long-term residue, will be absorbed by plants, enriched by the food chain, endangering high nutrient level organisms. For example, aquatic organisms contain 1,2-dichlorobenzene-d4 water for a long time, physiological functions may be disturbed, and population numbers may change.
As for human health, after respiratory tract, skin contact or accidental ingestion into the body, it can irritate the eyes and respiratory mucosa, causing cough, sore throat, breathing difficulties, etc. It can also affect the nervous system, causing dizziness, headache, fatigue, and even damage to liver and kidney function. Long-term exposure may increase the risk of cancer, because some halogenated aromatic hydrocarbons have been proven to be carcinogens, 1,2-dichlorobenzene-d4 structure is related to it, or potentially carcinogenic.
Therefore, the use and discharge of 1,2-dichlorobenzene-d4 should be strictly controlled to reduce its harm to the environment and human health.
1,2-dichloroethane-D4 As an isotope marker of 1,2-dichloroethane, it is widely used in the field of scientific research. First, it is of great significance for the study of chemical reaction mechanism. By tracking the whereabouts of labeled atoms in the reaction process, it can gain insight into the specific steps and paths of the reaction, which is like providing chemists with a pair of "discerning eyes" that can see the microscopic reaction world clearly, helping them clarify the essence of complex reactions and contributing to the development of chemical theory.
Second, in environmental science research, it can be used to trace the migration and transformation of pollutants. Due to its chemical properties similar to ordinary 1,2-dichloroethane, it can be precisely located by virtue of its isotopic characteristics, so it can help researchers know the diffusion, degradation and fate of pollutants in environmental media (such as soil, water, atmosphere), providing a key basis for environmental pollution control and prevention and control.
Third, it plays an extraordinary role in drug metabolism research. When 1,2-dichloroethane-related metabolic studies are involved in the process of drug development, 1,2-dichloroethane-D4 can be used to label drug molecules, observe the metabolism process of drugs in organisms, including the generation of metabolites, metabolic rates, etc., and provide strong support for new drug development and optimization of drug treatment plans.
Looking at its properties, it is mostly a colorless and transparent liquid at room temperature and pressure, just like clear water. Its smell is not pungent, but it has a mild fragrance, just like a light fragrance in a quiet night, lingering leisurely.
When it comes to volatility, 1% 2C2-dioxacyclohexane-d4 has strong volatilization properties, just like a smart spirit, which is easily converted from liquid to gaseous state and dances lightly in the air. This characteristic makes it necessary to pay special attention to the control of its volatilization in related operations to avoid escape.
Solubility is also one of its important properties. This compound has good solubility in water and many organic solvents. It is like a warm and hospitable person who can closely fuse with water and organic solvents such as ethanol and ether to form a uniform mixed system.
Its density is slightly larger than that of water. When placed in water, it will slowly sink, showing its own sense of weight. As for the melting point and boiling point, the melting point is about -42 ° C, just like the cold of winter, and it needs to be condensed at a lower temperature. The boiling point is about 101 ° C, and when heated moderately, it will boil and turn into curling steam.
In addition, the stability of 1% 2C2-dioxane-d4 is relatively good. Under normal conditions, it is not easy to chemically react with other substances, just like a calm person, content with its own state. However, in the presence of a specific temperature, pressure or catalyst, it will also show active reactivity and participate in various chemical changes.
Under normal circumstances, 1,2-dichlorobenzene-D4 has a certain solubility in common organic solvents under normal environmental conditions, and its chemical stability is quite high at room temperature and pressure. Due to the conjugated system of the benzene ring in the molecular structure, the molecule is relatively stable, and the substitution of two chlorine atoms has an impact on the electron cloud distribution of the benzene ring, but it does not significantly damage its stability.
However, under extreme conditions such as high temperature, strong oxidants or specific catalysts, 1,2-dichlorobenzene-D4 can also undergo chemical reactions. For example, at high temperatures and in the presence of catalysts, it may participate in nucleophilic substitution reactions, and chlorine atoms can be replaced by other nucleophilic reagents; in strong oxidation environments, the benzene ring structure may be destroyed and oxidation reactions occur.
However, for general chemical operation and storage, under suitable conditions, the chemical properties of 1,2-dichlorobenzene-D4 are sufficient to maintain stability, and it is not prone to spontaneous chemical changes. Therefore, it can be used as a relatively stable chemical raw material or tracer substance in specific experiments or industrial processes.
It is a toxic and harmful substance, and the storage place must be strictly selected. A cool and ventilated warehouse should be selected, away from fire and heat sources, to prevent danger caused by excessive temperature. The temperature of the warehouse should be strictly controlled within a specific range, and the humidity should also be properly adjusted to avoid environmental factors that cause its properties to change. And it must be stored separately from oxidants, acids, bases, etc., and must not be mixed. Because it encounters with these substances, it is very likely to trigger violent chemical reactions and cause serious consequences such as explosion.
The choice of storage container is also crucial. Containers that can ensure a good seal must be selected to prevent leakage of 1,2-dichloroethane-D4. At the same time, the material of the container should be able to withstand its corrosion to avoid leakage due to damage to the container. In a prominent position of the container, its name, characteristics, hazards and other important information should be clearly marked for identification and treatment.
When transporting, the transportation vehicle must meet the relevant safety standards. Equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment to prevent accidents. During transportation, to ensure that the container does not tip over, fall or damage, the driving route should try to avoid densely populated areas and busy traffic sections. Escort personnel must have professional knowledge, be familiar with its characteristics and emergency treatment methods, and closely monitor the transportation situation throughout the process.
The loading and unloading process also requires careful operation. Operators should wear appropriate protective equipment, such as gas masks, protective gloves, etc., to avoid direct contact. The loading and unloading actions must be gentle to prevent the container from being damaged due to violent actions such as collision and dragging.
In short, every step of the storage and transportation of 1,2-dichloroethane-D4 is related to safety. Only by strictly following relevant norms and requirements can we ensure foolproof.
At the environmental level, 1,2-Dichloroethane-d4 is volatile and will escape to the atmosphere. It participates in atmospheric chemical reactions through light and other effects, which affects air quality. It is difficult to degrade in soil, will accumulate residues, may pollute the soil, affect the soil ecosystem, and cause negative effects on the growth and development of microorganisms and plants in the soil. If it enters the water body, it will pollute the water quality. Because it is insoluble in water and heavier than water, it will deposit on the bottom of the water, affecting the survival and reproduction of aquatic organisms, and destroying the balance of aquatic ecology.
As far as human health is concerned, 1,2-dichloroethane-d4 can enter the human body through respiratory tract, skin contact, accidental ingestion and other routes. It has inhibitory effects on the central nervous system. When people are exposed to high concentrations for a short time, it will cause dizziness, headache, fatigue, drowsiness, nausea, vomiting and other symptoms, and even coma and convulsion in severe cases, which is life-threatening. Long-term exposure to low concentrations will damage the functions of organs such as the liver and kidneys, and may cause hepatomegaly, abnormal liver function, and kidney function decline. In addition, this substance is also potentially carcinogenic, and long-term exposure may increase the risk of cancer. Therefore, when using and handling 1,2-dichloroethane-d4, proper protective measures must be taken to avoid damage to the environment and human health.

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