Linshang Chemical
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1,3,4-Trichlorobenzene
Linshang Chemical
|
HS Code |
867989 |
| Chemical Formula | C6H3Cl3 |
| Molar Mass | 181.45 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Odor | Pungent, aromatic odor |
| Density | 1.455 g/cm³ at 20 °C |
| Boiling Point | 213 - 214 °C |
| Melting Point | -22 °C |
| Solubility In Water | Very slightly soluble |
| Solubility In Organic Solvents | Soluble in most organic solvents |
| Vapor Pressure | 0.13 kPa at 44.8 °C |
| Log Kow Octanol Water Partition Coefficient | 4.09 |
As an accredited 1,3,4-Trichlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500 - gram bottle of 1,3,4 - trichlorobenzene with tight - sealed chemical - resistant packaging. |
| Storage | 1,3,4 - Trichlorobenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances. Ensure the storage place has proper spill - containment measures to handle any potential leaks safely. |
| Shipping | 1,3,4 - Trichlorobenzene is shipped in specialized containers, compliant with hazardous chemical regulations. It's carefully packaged to prevent leaks during transportation, ensuring safety of handlers and the environment. |
Competitive 1,3,4-Trichlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1,3,4-Trichlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is 1,3,4-trichlorobenzene?
1,3,4-Trifluorobenzene is an organic compound. Its molecule contains a benzene ring, and the 1, 3, and 4 positions on the benzene ring are replaced by fluorine atoms. This substance is widely used in the chemical industry.
Looking at its physical properties, 1,3,4-trifluorobenzene is mostly a colorless and transparent liquid at room temperature, with a special odor. Its boiling point, melting point and other properties are determined by the interaction between atoms and the force between molecules. Generally speaking, fluorine-containing organic compounds have a significant impact on molecular properties due to the large electronegativity of fluorine atoms. The same is true for 1,3,4-trifluorobenzene. Its boiling point may be changed due to the introduction of fluorine atoms.
On chemical properties, the benzene ring in 1,3,4-trifluorobenzene is aromatic and can undergo electrophilic substitution reactions. Because the fluorine atom is an ortho-para-localization group, when the electrophilic reagent attacks the benzene ring, it is mostly in the ortho-site or para-site of the fluorine atom. At the same time, the electronegativity of the fluorine atom is large, which reduces the electron cloud density of the benzene ring, and the electrophilic substitution reaction activity is slightly lower than that of benzene.
1,3,4-trifluorobenzene has a wide range of uses in the field of organic synthesis. First, it can be used as a pharmaceutical intermediate to synthesize drugs with specific physiological activities through a series of chemical reactions. Second, in the field of pesticides, it is a key raw material for the synthesis of new pesticides. Based on it, pesticides may be highly efficient, low toxic, and environmentally friendly. Third, in the field of materials science, or used to synthesize special performance polymer materials, such as fluoropolymers, such materials may have excellent weather resistance
1,3,4-trifluorobenzene, as an important organic compound, plays a key role in many fields of chemical industry due to its unique structure. With the development of science and technology, its application prospect may be broader.
Looking at its physical properties, 1,3,4-trifluorobenzene is mostly a colorless and transparent liquid at room temperature, with a special odor. Its boiling point, melting point and other properties are determined by the interaction between atoms and the force between molecules. Generally speaking, fluorine-containing organic compounds have a significant impact on molecular properties due to the large electronegativity of fluorine atoms. The same is true for 1,3,4-trifluorobenzene. Its boiling point may be changed due to the introduction of fluorine atoms.
On chemical properties, the benzene ring in 1,3,4-trifluorobenzene is aromatic and can undergo electrophilic substitution reactions. Because the fluorine atom is an ortho-para-localization group, when the electrophilic reagent attacks the benzene ring, it is mostly in the ortho-site or para-site of the fluorine atom. At the same time, the electronegativity of the fluorine atom is large, which reduces the electron cloud density of the benzene ring, and the electrophilic substitution reaction activity is slightly lower than that of benzene.
1,3,4-trifluorobenzene has a wide range of uses in the field of organic synthesis. First, it can be used as a pharmaceutical intermediate to synthesize drugs with specific physiological activities through a series of chemical reactions. Second, in the field of pesticides, it is a key raw material for the synthesis of new pesticides. Based on it, pesticides may be highly efficient, low toxic, and environmentally friendly. Third, in the field of materials science, or used to synthesize special performance polymer materials, such as fluoropolymers, such materials may have excellent weather resistance
1,3,4-trifluorobenzene, as an important organic compound, plays a key role in many fields of chemical industry due to its unique structure. With the development of science and technology, its application prospect may be broader.
What are the main uses of 1,3,4-trichlorobenzene?
1,3,4-Trifluorobenzene is widely used and has important applications in many fields such as medicine, pesticides, and materials.
In the field of medicine, it is a key pharmaceutical intermediate. With it, compounds with special biological activities can be synthesized, such as some antiviral and anti-tumor drugs. Due to its fluorine atom properties, it can change the physical and chemical properties and biological activities of drug molecules, making it easier for drugs to penetrate cell membranes and improve drug efficacy and stability. For example, in the development of a new antiviral drug, 1,3,4-trifluorobenzene participates in the construction of key structural fragments, which significantly enhances the inhibitory effect of the drug on viral proteases.
In the field of pesticides, this is an important raw material for the synthesis of high-efficiency and low-toxicity pesticides. The introduction of fluorine atoms into pesticide molecules can improve the activity and selectivity of pesticides to target organisms, reduce the impact on non-target organisms, and enhance the environmental stability and shelf life of pesticides. For example, some insecticides containing the structure of 1,3,4-trifluorobenzene have good poisoning effect on specific pests, and have little impact on the surrounding ecological environment.
In the field of materials, 1,3,4-trifluorobenzene can be used to prepare high-performance polymer materials. Introducing it into the polymer backbone or side chain can endow the material with unique properties, such as excellent thermal stability, chemical stability and electrical properties. For example, in electronic materials, polymers containing this structure are often used to make high-performance insulating materials and liquid crystal display materials to meet the high-performance requirements of electronic devices.
In addition, in the field of organic synthesis, 1,3,4-trifluorobenzene, as an important fluorinated building block, provides the foundation for the construction of complex fluorinated organic compounds and promotes the development of organofluorine chemistry. Its diverse reactivity and unique structure provide more possibilities for organic synthesis chemists to design novel compounds, promote the emergence of new organofluorine compounds, and expand the boundaries of organic synthesis chemistry.
In the field of medicine, it is a key pharmaceutical intermediate. With it, compounds with special biological activities can be synthesized, such as some antiviral and anti-tumor drugs. Due to its fluorine atom properties, it can change the physical and chemical properties and biological activities of drug molecules, making it easier for drugs to penetrate cell membranes and improve drug efficacy and stability. For example, in the development of a new antiviral drug, 1,3,4-trifluorobenzene participates in the construction of key structural fragments, which significantly enhances the inhibitory effect of the drug on viral proteases.
In the field of pesticides, this is an important raw material for the synthesis of high-efficiency and low-toxicity pesticides. The introduction of fluorine atoms into pesticide molecules can improve the activity and selectivity of pesticides to target organisms, reduce the impact on non-target organisms, and enhance the environmental stability and shelf life of pesticides. For example, some insecticides containing the structure of 1,3,4-trifluorobenzene have good poisoning effect on specific pests, and have little impact on the surrounding ecological environment.
In the field of materials, 1,3,4-trifluorobenzene can be used to prepare high-performance polymer materials. Introducing it into the polymer backbone or side chain can endow the material with unique properties, such as excellent thermal stability, chemical stability and electrical properties. For example, in electronic materials, polymers containing this structure are often used to make high-performance insulating materials and liquid crystal display materials to meet the high-performance requirements of electronic devices.
In addition, in the field of organic synthesis, 1,3,4-trifluorobenzene, as an important fluorinated building block, provides the foundation for the construction of complex fluorinated organic compounds and promotes the development of organofluorine chemistry. Its diverse reactivity and unique structure provide more possibilities for organic synthesis chemists to design novel compounds, promote the emergence of new organofluorine compounds, and expand the boundaries of organic synthesis chemistry.
What are the environmental effects of 1,3,4-trichlorobenzene?
1% 2C3% 2C4-tribromobenzene, its impact on the environment cannot be ignored. This substance is toxic to a certain extent, and in the natural environment, it may be difficult to degrade, which may cause environmental pollution.
To observe the aquatic ecology, if 1% 2C3% 2C4-tribromobenzene enters the water body, aquatic organisms will bear the brunt. It may affect the physiological functions of fish, shellfish, etc., causing their growth and development to be blocked, and even life-threatening. And this substance may accumulate in aquatic organisms and pass through the food chain, which will eventually harm humans.
In the soil environment, 1% 2C3% 2C4-tribromobenzene can change the structure and function of soil microbial community. Microorganisms are essential for soil material circulation and nutrient transformation. If they are affected, the soil ecological balance may be destroyed, resulting in a decrease in soil fertility and hindering plant growth.
In the atmospheric environment, 1% 2C3% 2C4-tribromobenzene volatilizes, or forms an aerosol, which affects air quality. If inhaled by humans, or damaging the respiratory system, it may cause respiratory diseases and endanger human health.
In addition, the existence of 1% 2C3% 2C4-tribromobenzene may interfere with the energy flow and material cycle of the ecosystem. The ecosystem is an organic whole, and one ring is damaged, and other rings are also implicated. Its impact on the environment is extensive and far-reaching, and we need to treat it cautiously and take effective measures to reduce its harm and ensure environmental safety and ecological balance.
To observe the aquatic ecology, if 1% 2C3% 2C4-tribromobenzene enters the water body, aquatic organisms will bear the brunt. It may affect the physiological functions of fish, shellfish, etc., causing their growth and development to be blocked, and even life-threatening. And this substance may accumulate in aquatic organisms and pass through the food chain, which will eventually harm humans.
In the soil environment, 1% 2C3% 2C4-tribromobenzene can change the structure and function of soil microbial community. Microorganisms are essential for soil material circulation and nutrient transformation. If they are affected, the soil ecological balance may be destroyed, resulting in a decrease in soil fertility and hindering plant growth.
In the atmospheric environment, 1% 2C3% 2C4-tribromobenzene volatilizes, or forms an aerosol, which affects air quality. If inhaled by humans, or damaging the respiratory system, it may cause respiratory diseases and endanger human health.
In addition, the existence of 1% 2C3% 2C4-tribromobenzene may interfere with the energy flow and material cycle of the ecosystem. The ecosystem is an organic whole, and one ring is damaged, and other rings are also implicated. Its impact on the environment is extensive and far-reaching, and we need to treat it cautiously and take effective measures to reduce its harm and ensure environmental safety and ecological balance.
What are the hazards of 1,3,4-trichlorobenzene to human health?
1% 2C3% 2C4-tribromobenzene, its harm to human health should not be underestimated. This is a toxic chemical with irritation and potential harm.
If people accidentally touch it, it can cause redness, swelling, itching, and burning on the skin. Or due to individual differences, the degree of reaction varies, but it should not be ignored. When it touches the eyes, it is especially harmful. If it is light, it causes discomfort to the eyes, tears flow, and in severe cases, it may damage vision and cause eye diseases.
If inhaled through the mouth and nose, it enters the lungs and can irritate the respiratory tract, causing cough, asthma, and breathing difficulties. Exposure to this environment for a long time makes it more susceptible to lung diseases, such as pneumonia and emphysema, which endanger life.
If accidentally ingested, the harm will also be serious. It can irritate the stomach, cause nausea, vomiting, abdominal pain, diarrhea. It even damages the liver, kidneys and other organs, causing organ dysfunction, affecting the metabolism and function of the whole body.
And this chemical may pose a risk of carcinogenesis. Although the relevant studies may not be fully clear, many experiments and observations suggest its potential carcinogenicity. Long-term exposure to it may increase the risk of cancer.
Therefore, in life and work, it is necessary to take strict precautions against 1% 2C3% 2C4-tribromobenzene. When working, use protective gear, such as gloves, masks, goggles, etc., to ensure your own safety. If you accidentally touch it, rinse it with plenty of water immediately and seek medical attention immediately without delay.
If people accidentally touch it, it can cause redness, swelling, itching, and burning on the skin. Or due to individual differences, the degree of reaction varies, but it should not be ignored. When it touches the eyes, it is especially harmful. If it is light, it causes discomfort to the eyes, tears flow, and in severe cases, it may damage vision and cause eye diseases.
If inhaled through the mouth and nose, it enters the lungs and can irritate the respiratory tract, causing cough, asthma, and breathing difficulties. Exposure to this environment for a long time makes it more susceptible to lung diseases, such as pneumonia and emphysema, which endanger life.
If accidentally ingested, the harm will also be serious. It can irritate the stomach, cause nausea, vomiting, abdominal pain, diarrhea. It even damages the liver, kidneys and other organs, causing organ dysfunction, affecting the metabolism and function of the whole body.
And this chemical may pose a risk of carcinogenesis. Although the relevant studies may not be fully clear, many experiments and observations suggest its potential carcinogenicity. Long-term exposure to it may increase the risk of cancer.
Therefore, in life and work, it is necessary to take strict precautions against 1% 2C3% 2C4-tribromobenzene. When working, use protective gear, such as gloves, masks, goggles, etc., to ensure your own safety. If you accidentally touch it, rinse it with plenty of water immediately and seek medical attention immediately without delay.
What are the production methods for 1,3,4-trichlorobenzene?
There are several methods for preparing 1% 2C3% 2C4-tribromobenzene.
One is to use benzene as the starting material and prepare it by bromination reaction. Under appropriate reaction conditions, benzene and bromine can undergo electrophilic substitution reaction under the action of catalysts such as ferric chloride. However, if this reaction is carried out directly, a mixture of bromobenzene, dibromobenzene and tribromobenzene is often obtained. It needs to be carefully separated and purified to obtain a relatively pure 1% 2C3% 2C4-tribromobenzene. During the process, it is crucial to control the reaction temperature, the amount of bromine and the reaction time. If the temperature is too high, the reaction rate will increase, but there will be many side reactions, and the selectivity of the product will decrease. If the amount of bromine is too high, more polybrominates will be easily generated. If the reaction time is too short, the reaction will be incomplete.
The second can be started from the corresponding substituted benzene and go through a specific conversion step. For example, using m-dibromobenzene as a raw material, through appropriate positioning group guidance, the bromination reaction will be carried out. Using the influence of the positioning group on the electron cloud density at different positions on the benzene ring, the bromine atom selectively enters the target position, thereby obtaining 1% 2C3% 2C4-tribromobenzene. This approach requires a deep understanding of the properties and reaction mechanism of the positioning groups, and the subsequent removal or transformation of the positioning groups needs to be properly designed to ensure the purity and yield of the product.
Or some more novel organic synthesis methods can be used, such as the reaction catalyzed by transition metals. Transition metal catalysts can precisely regulate the selectivity and activity of the reaction. Through rational design of reaction substrates and ligands, it is possible to efficiently synthesize 1% 2C3% 2C4-tribromobenzene. However, such methods often require more complex reaction conditions and expensive catalysts, and the requirements for reaction operation are quite high. They need to be carried out in strict environments such as anhydrous and anaerobic to ensure the activity of the catalyst and the smooth progress of the reaction.
One is to use benzene as the starting material and prepare it by bromination reaction. Under appropriate reaction conditions, benzene and bromine can undergo electrophilic substitution reaction under the action of catalysts such as ferric chloride. However, if this reaction is carried out directly, a mixture of bromobenzene, dibromobenzene and tribromobenzene is often obtained. It needs to be carefully separated and purified to obtain a relatively pure 1% 2C3% 2C4-tribromobenzene. During the process, it is crucial to control the reaction temperature, the amount of bromine and the reaction time. If the temperature is too high, the reaction rate will increase, but there will be many side reactions, and the selectivity of the product will decrease. If the amount of bromine is too high, more polybrominates will be easily generated. If the reaction time is too short, the reaction will be incomplete.
The second can be started from the corresponding substituted benzene and go through a specific conversion step. For example, using m-dibromobenzene as a raw material, through appropriate positioning group guidance, the bromination reaction will be carried out. Using the influence of the positioning group on the electron cloud density at different positions on the benzene ring, the bromine atom selectively enters the target position, thereby obtaining 1% 2C3% 2C4-tribromobenzene. This approach requires a deep understanding of the properties and reaction mechanism of the positioning groups, and the subsequent removal or transformation of the positioning groups needs to be properly designed to ensure the purity and yield of the product.
Or some more novel organic synthesis methods can be used, such as the reaction catalyzed by transition metals. Transition metal catalysts can precisely regulate the selectivity and activity of the reaction. Through rational design of reaction substrates and ligands, it is possible to efficiently synthesize 1% 2C3% 2C4-tribromobenzene. However, such methods often require more complex reaction conditions and expensive catalysts, and the requirements for reaction operation are quite high. They need to be carried out in strict environments such as anhydrous and anaerobic to ensure the activity of the catalyst and the smooth progress of the reaction.
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