Linshang Chemical
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1,3,5-Fluorochloro-Bromobenzene
Linshang Chemical
|
HS Code |
338471 |
| Chemical Formula | C6H2ClF3Br |
| Molar Mass | 245.43 g/mol |
| Appearance | colorless to pale yellow liquid |
| Boiling Point | approx. 165 - 170 °C |
| Density | data may vary, typically in range of halogenated benzenes |
| Solubility In Water | insoluble |
| Solubility In Organic Solvents | soluble in many organic solvents like ethanol, ether |
| Vapor Pressure | low, specific value depends on temperature |
| Flash Point | data may vary, should be handled as flammable |
As an accredited 1,3,5-Fluorochloro-Bromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram vial of 1,3,5 - fluorochloro - bromobenzene, tightly sealed for safe storage. |
| Storage | 1,3,5 - Fluorochloro - bromobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames as it is likely flammable. Keep it in a tightly - sealed container to prevent vapor release. Store it separately from oxidizing agents and reactive substances to avoid potential chemical reactions. Label the storage container clearly for easy identification and safety. |
| Shipping | 1,3,5 - Fluorochloro - bromobenzene, a chemical, is shipped in sealed, corrosion - resistant containers. They are carefully packaged to prevent leaks, transported under regulated conditions to avoid temperature - related risks, ensuring safe transit. |
Competitive 1,3,5-Fluorochloro-Bromobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1,3,5-Fluorochloro-Bromobenzene in China?
As a trusted 1,3,5-Fluorochloro-Bromobenzene manufacturer, we deliver:
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1,3,5-Fluorochloro-Bromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 5-fluorochloro-bromobenzene?
1% 2C3% 2C5-fluorochloro-bromobenzene is 1,3,5-fluorochlorobenzene. Its chemical structure is on the benzene ring, with fluorine atoms (F), chlorine atoms (Cl) and bromine atoms (Br) connected at positions 1, 3, and 5, respectively. The benzene ring is a six-membered ring structure, with six carbon atoms connected to each other by covalent bonds to form a regular hexagon, each carbon atom is connected to a hydrogen atom. However, in 1,3,5-fluorochlorobenzene, the hydrogen atoms at positions 1, 3, and 5 are replaced by fluorine, chlorine, and bromine atoms. This structure makes the compound have unique physical and chemical properties. Due to the different electronegativity of fluorine, chlorine and bromine atoms, it will affect the distribution of benzene ring electron cloud, and then affect its reactivity and intermolecular forces. This structure may have important uses in organic synthesis, pharmaceutical chemistry and other fields, and can be used as a key intermediate for the synthesis of more complex organic compounds.
What are the physical properties of 5-fluorochloro-bromobenzene?
1% 2C3% 2C5 -fluorochloro-bromobenzene is an organic compound. Its physical properties are particularly important and are related to many applications of this compound.
First of all, its appearance, under room temperature and pressure, is often colorless to light yellow liquid, clear and transparent, and its luster flow can be seen under light, which is quite characteristic. This appearance characteristic can be an important basis for the identification and preliminary understanding of the compound.
When it comes to boiling point, the boiling point of 1% 2C3% 2C5 -fluorochloro-bromobenzene is within a certain range due to factors such as intermolecular forces. The value of its boiling point is crucial in the process of separating and purifying this compound. By means of distillation, the temperature can be controlled to reach the vicinity of its boiling point, so that the compound can be separated from other substances with different boiling points to obtain pure products.
Melting point is also one of its key physical properties. The melting point of the compound is specific. When the ambient temperature drops below the melting point, it gradually changes from liquid to solid state, and the morphological change can be observed. This characteristic needs to be taken into account when storing and using the compound under specific conditions.
Furthermore, the density cannot be ignored. 1% 2C3% 2C5 - fluorochloro - brobenmozene has a certain density, which may be different from that of water. This difference is significant when it comes to operations such as liquid-liquid separation. If its density is greater than that of water, after the mixed system is left to stand, it will sink to the bottom of the water, which can be used to achieve preliminary separation of foreign matter with the same density as water.
In terms of solubility, it often exhibits good solubility in organic solvents, such as some aromatic hydrocarbons, halogenated hydrocarbons, etc. This property makes it can be used as a reactant or intermediate in organic synthesis reactions, participating in various chemical reactions in a suitable solvent environment to help the process of organic synthesis. However, in water, its solubility or poor solubility is also one of its physical properties. In practical application and treatment of systems containing this compound, careful attention should be paid.
In summary, the physical properties of 1% 2C3% 2C5 - fluorochloro - bromobenzene, such as appearance, boiling point, melting point, density, solubility, etc., are interrelated and have various uses. They are indispensable in many fields such as the research, production and application of organic chemistry.
First of all, its appearance, under room temperature and pressure, is often colorless to light yellow liquid, clear and transparent, and its luster flow can be seen under light, which is quite characteristic. This appearance characteristic can be an important basis for the identification and preliminary understanding of the compound.
When it comes to boiling point, the boiling point of 1% 2C3% 2C5 -fluorochloro-bromobenzene is within a certain range due to factors such as intermolecular forces. The value of its boiling point is crucial in the process of separating and purifying this compound. By means of distillation, the temperature can be controlled to reach the vicinity of its boiling point, so that the compound can be separated from other substances with different boiling points to obtain pure products.
Melting point is also one of its key physical properties. The melting point of the compound is specific. When the ambient temperature drops below the melting point, it gradually changes from liquid to solid state, and the morphological change can be observed. This characteristic needs to be taken into account when storing and using the compound under specific conditions.
Furthermore, the density cannot be ignored. 1% 2C3% 2C5 - fluorochloro - brobenmozene has a certain density, which may be different from that of water. This difference is significant when it comes to operations such as liquid-liquid separation. If its density is greater than that of water, after the mixed system is left to stand, it will sink to the bottom of the water, which can be used to achieve preliminary separation of foreign matter with the same density as water.
In terms of solubility, it often exhibits good solubility in organic solvents, such as some aromatic hydrocarbons, halogenated hydrocarbons, etc. This property makes it can be used as a reactant or intermediate in organic synthesis reactions, participating in various chemical reactions in a suitable solvent environment to help the process of organic synthesis. However, in water, its solubility or poor solubility is also one of its physical properties. In practical application and treatment of systems containing this compound, careful attention should be paid.
In summary, the physical properties of 1% 2C3% 2C5 - fluorochloro - bromobenzene, such as appearance, boiling point, melting point, density, solubility, etc., are interrelated and have various uses. They are indispensable in many fields such as the research, production and application of organic chemistry.
What are the preparation methods of 5-fluorochloro-bromobenzene?
1% 2C3% 2C5-fluorochloro-bromobenzene is 1,3,5-fluorochlorobenzene. There are many ways to prepare this compound, which will be described in detail below.
First, benzene can be started. First, bromine atoms are introduced into the benzene ring by a bromination reaction. Bromine and iron filings (or iron tribromide as a catalyst) are commonly used. Under heating conditions, benzene and bromine undergo an electrophilic substitution reaction to generate bromobenzene. Then, bromobenzene is chlorinated. With chlorine gas and bromobenzene, under the catalysis of light or ferric chloride, m-bromochlorobenzene can be obtained. Finally, the fluorination reaction is used to replace the fluorine atom with a fluorine source such as m-bromochlorobenzene and potassium fluoride under the action of an appropriate solvent and catalyst, and the final result is 1,3,5-fluorochlorobenzene. There are many steps in this process, and each step requires precise control of the conditions to ensure the purity and yield of the product.
Second, start from m-chloroaniline. First, m-chloroaniline is diazotized, and sodium nitrite and m-chloroaniline are reacted at low temperature in an acidic solution to obtain diazonium salts. Then the diazonium salt is reacted with cuprous bromide and hydrobromic acid, and the Sandmeier reaction occurs. The diazonium group is replaced by a bromine atom to obtain m-bromochlorobenzene. After the above method, the The key to this route is the diazotization reaction conditions, which are low temperature and need to be operated quickly to prevent the decomposition of diazonium salts.
Third, start with 1,3,5-tribromobenzene. Using a fluorine source (such as potassium fluoride) in a suitable organic solvent and catalyst system, some bromine atoms are replaced by fluorine atoms to form fluorobromobenzene. After chlorination, chlorine gas is used to introduce chlorine atoms into the benzene ring under specific conditions to obtain 1,3,5-fluorochlorobrobenzene. The focus of this path is to control the degree and position selectivity of fluorine and chlorine reactions.
In conclusion, the preparation of 1,3,5-chlorofluorobromobenzene involves different starting materials and reaction pathways. The actual synthesis requires comprehensive consideration of factors such as raw material availability, cost, reaction conditions, and difficulty in product separation and purification, and careful selection of suitable methods.
First, benzene can be started. First, bromine atoms are introduced into the benzene ring by a bromination reaction. Bromine and iron filings (or iron tribromide as a catalyst) are commonly used. Under heating conditions, benzene and bromine undergo an electrophilic substitution reaction to generate bromobenzene. Then, bromobenzene is chlorinated. With chlorine gas and bromobenzene, under the catalysis of light or ferric chloride, m-bromochlorobenzene can be obtained. Finally, the fluorination reaction is used to replace the fluorine atom with a fluorine source such as m-bromochlorobenzene and potassium fluoride under the action of an appropriate solvent and catalyst, and the final result is 1,3,5-fluorochlorobenzene. There are many steps in this process, and each step requires precise control of the conditions to ensure the purity and yield of the product.
Second, start from m-chloroaniline. First, m-chloroaniline is diazotized, and sodium nitrite and m-chloroaniline are reacted at low temperature in an acidic solution to obtain diazonium salts. Then the diazonium salt is reacted with cuprous bromide and hydrobromic acid, and the Sandmeier reaction occurs. The diazonium group is replaced by a bromine atom to obtain m-bromochlorobenzene. After the above method, the The key to this route is the diazotization reaction conditions, which are low temperature and need to be operated quickly to prevent the decomposition of diazonium salts.
Third, start with 1,3,5-tribromobenzene. Using a fluorine source (such as potassium fluoride) in a suitable organic solvent and catalyst system, some bromine atoms are replaced by fluorine atoms to form fluorobromobenzene. After chlorination, chlorine gas is used to introduce chlorine atoms into the benzene ring under specific conditions to obtain 1,3,5-fluorochlorobrobenzene. The focus of this path is to control the degree and position selectivity of fluorine and chlorine reactions.
In conclusion, the preparation of 1,3,5-chlorofluorobromobenzene involves different starting materials and reaction pathways. The actual synthesis requires comprehensive consideration of factors such as raw material availability, cost, reaction conditions, and difficulty in product separation and purification, and careful selection of suitable methods.
What are the main uses of 5-fluorochloro-bromobenzene?
1% 2C3% 2C5-fluorochloro-bromobenzene is 1,3,5-fluorochlorobenzene, which is widely used in the field of chemical synthesis.
First, in the process of new drug development, 1,3,5-fluorochlorobenzene plays a key role. Because of its unique chemical structure, it can be used as an important intermediate. Medicinal chemists can construct compounds with specific pharmacological activities by modifying and modifying their structures. For example, in the development of anti-cancer drugs, using this as a starting material and introducing different active groups through multi-step reactions can create new drugs that target cancer cells, which is expected to provide a new way to solve the cancer problem.
Second, in the field of materials science, 1,3,5-chlorofluorobromobenzene also has outstanding performance. It can participate in the synthesis of high-performance polymers. When preparing special engineering plastics, introducing them into the polymer main chain or side chain can effectively improve the thermal stability, mechanical properties and chemical resistance of the material. Such as high-end composite materials used in the aerospace field, after adding such compounds, they can better adapt to extreme environments and ensure the safety and performance of aircraft.
Furthermore, in the field of organic synthetic chemistry, 1,3,5-chlorofluorobrobenzene is often used as a basic raw material. Organic chemists can use it to perform various classical reactions, such as nucleophilic substitution reactions, metal catalytic coupling reactions, etc., to synthesize a series of organic compounds with complex structures and specific functions. These compounds are widely used in flavors, dyes, pesticides and many other industries, greatly enriching the variety of organic compounds and promoting the development of related industries.
First, in the process of new drug development, 1,3,5-fluorochlorobenzene plays a key role. Because of its unique chemical structure, it can be used as an important intermediate. Medicinal chemists can construct compounds with specific pharmacological activities by modifying and modifying their structures. For example, in the development of anti-cancer drugs, using this as a starting material and introducing different active groups through multi-step reactions can create new drugs that target cancer cells, which is expected to provide a new way to solve the cancer problem.
Second, in the field of materials science, 1,3,5-chlorofluorobromobenzene also has outstanding performance. It can participate in the synthesis of high-performance polymers. When preparing special engineering plastics, introducing them into the polymer main chain or side chain can effectively improve the thermal stability, mechanical properties and chemical resistance of the material. Such as high-end composite materials used in the aerospace field, after adding such compounds, they can better adapt to extreme environments and ensure the safety and performance of aircraft.
Furthermore, in the field of organic synthetic chemistry, 1,3,5-chlorofluorobrobenzene is often used as a basic raw material. Organic chemists can use it to perform various classical reactions, such as nucleophilic substitution reactions, metal catalytic coupling reactions, etc., to synthesize a series of organic compounds with complex structures and specific functions. These compounds are widely used in flavors, dyes, pesticides and many other industries, greatly enriching the variety of organic compounds and promoting the development of related industries.
1, 3, 5-fluorochloro-bromobenzene What are the precautions in storage and transportation?
1% 2C3% 2C5 - fluorochloro - bromobenzene is an organic compound containing halogen atoms such as fluorine, chlorine, and bromine. When storing and transporting these compounds, many matters should be paid attention to, as detailed below:
** Precautions for storage **:
First, because of its chemical activity, it should be stored in a cool and ventilated warehouse. This environment can reduce the possibility of reaction with external factors. If the warehouse temperature is too high or the ventilation is poor, or the volatile compound is intensified, and even chemical reactions are caused, resulting in dangerous occurrence.
Second, keep away from fire and heat sources. Halogenated benzene compounds are flammable, and are easy to burn in case of open flames and hot topics, resulting in fire accidents.
Third, it should be stored separately from oxidants and edible chemicals, and should not be mixed. Because of its contact with oxidants or violent oxidation reactions, it should be mixed with edible chemicals, or cause accidental ingestion, endangering human health.
Fourth, the storage area should be equipped with suitable materials to contain leaks. To prevent compound leakage, it can be dealt with in time and effectively to reduce its harm to the environment and human body.
** Precautions for transportation **:
First, before transportation, it is necessary to ensure that the packaging is complete and the loading is safe. The packaging should have good sealing and impact resistance to prevent package damage due to bumps and collisions during transportation and compound leakage.
Second, when transporting, you should follow the specified route and do not stop in densely populated areas and residential areas. Because the compound may be toxic and dangerous, once it leaks, it will cause serious consequences in densely populated areas.
Third, transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. In case of fire or leakage accidents, you can respond in time to reduce the degree of harm.
Fourth, during transportation, you should prevent exposure to the sun, rain, and high temperature. External environmental factors may affect the stability of the compound, causing it to decompose and evaporate.
** Precautions for storage **:
First, because of its chemical activity, it should be stored in a cool and ventilated warehouse. This environment can reduce the possibility of reaction with external factors. If the warehouse temperature is too high or the ventilation is poor, or the volatile compound is intensified, and even chemical reactions are caused, resulting in dangerous occurrence.
Second, keep away from fire and heat sources. Halogenated benzene compounds are flammable, and are easy to burn in case of open flames and hot topics, resulting in fire accidents.
Third, it should be stored separately from oxidants and edible chemicals, and should not be mixed. Because of its contact with oxidants or violent oxidation reactions, it should be mixed with edible chemicals, or cause accidental ingestion, endangering human health.
Fourth, the storage area should be equipped with suitable materials to contain leaks. To prevent compound leakage, it can be dealt with in time and effectively to reduce its harm to the environment and human body.
** Precautions for transportation **:
First, before transportation, it is necessary to ensure that the packaging is complete and the loading is safe. The packaging should have good sealing and impact resistance to prevent package damage due to bumps and collisions during transportation and compound leakage.
Second, when transporting, you should follow the specified route and do not stop in densely populated areas and residential areas. Because the compound may be toxic and dangerous, once it leaks, it will cause serious consequences in densely populated areas.
Third, transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. In case of fire or leakage accidents, you can respond in time to reduce the degree of harm.
Fourth, during transportation, you should prevent exposure to the sun, rain, and high temperature. External environmental factors may affect the stability of the compound, causing it to decompose and evaporate.
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