1,3,6-Fluorochlorobromobenzene
Linshang Chemical
HS Code |
775015 |
Chemical Formula | C6H2ClF3Br |
Molar Mass | 245.43 g/mol |
Appearance | Colorless to pale yellow liquid |
Boiling Point | 160 - 162 °C |
Density | 1.85 - 1.89 g/cm³ |
Solubility In Water | Insoluble |
Flash Point | 60 °C |
Refractive Index | 1.498 - 1.502 |
As an accredited 1,3,6-Fluorochlorobromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 100g of 1,3,6 - fluorochlorobromobenzene packaged in a sealed, chemical - resistant bottle. |
Storage | 1,3,6 - fluorochlorobromobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reactive chemicals, and foodstuff to prevent potential reactions and contamination. |
Shipping | 1,3,6 - fluorochlorobromobenzene, a chemical, is shipped in specialized, tightly - sealed containers. These containers are designed to prevent leakage and ensure safe transport, following strict regulations for hazardous chemicals. |
Competitive 1,3,6-Fluorochlorobromobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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As a leading 1,3,6-Fluorochlorobromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In this structure, the hydrogen atoms at positions 1, 3, and 6 are replaced by fluorine (F), chlorine (Cl), and bromine (Br) atoms, respectively. According to the system nomenclature rules, the number of the benzene ring substituents needs to minimize the sum of the substituent positions. Therefore, the fluorine, chlorine, and bromine atoms in this compound are located at positions 1, 3, and 6 on the benzene ring, respectively.
This compound is endowed with unique physical and chemical properties due to the presence of different halogen atoms. Different halogen atoms have different electronegativity, which will affect the physical properties such as molecular polarity, boiling point, and melting point. In terms of chemical properties, halogen atoms can participate in a variety of chemical reactions, such as nucleophilic substitution reactions. Because halogen atoms have a certain tendency to leave, they can be replaced by other nucleophilic reagents, and then used to synthesize more complex organic compounds. The chemical structure of 1,3,6-fluorochlorobromobenzene is composed of benzene rings and fluorine, chlorine, and bromine substituents at specific sites. This structural feature determines its importance and potential application value in the field of organic synthesis and chemistry research.
Looking at its physical properties, it is mostly liquid or solid at room temperature, because of the intermolecular force. Its melting and boiling point is closely related to the molecular structure. Because the molecule contains fluorine, chlorine, and bromine halogen atoms, the halogen atoms have strong electronegativity, which increases the molecular polarity and enhances the intermolecular force, so the melting and boiling point is relatively high.
Furthermore, the solubility of this compound also has characteristics. In water, it is difficult to dissolve because its polarity is different from that of water molecules. However, in organic solvents such as benzene, carbon tetrachloride and other non-polar or weakly polar solvents, due to the principle of similar phase dissolution, it has better solubility.
Its density is greater than that of water, because the relative atomic weight of halogen atoms is larger, which increases the molecular weight, so the density is higher than that of water. In chemical synthesis, this density characteristic can be used to separate and purify, and by virtue of the difference between its density and water, the technique of liquid separation is performed.
In addition, 1% 2C3% 2C6 - fluorochlorobromobenzene has a certain degree of volatility, but the degree of volatilization varies depending on the ambient temperature and pressure. Under high temperature and low pressure environment, the volatilization intensifies. When volatilizing, the smell is special, and because it contains halogen atoms, steam may have a certain irritation. Pay attention to ventilation during operation to ensure The physical properties of
1% 2C3% 2C6 - fluorochlorobromobenzene are diverse, and they need to be properly operated and utilized according to their characteristics in chemical production and experimental research.
First, halogenation reaction method. Take benzene as the starting material, first introduce one of the halogen atoms through halogenation reaction. If benzene and bromine are catalyzed by iron bromide, bromobenzene can be obtained. Then, with suitable reaction conditions and reagents, chlorine atoms and fluorine atoms are introduced in turn. However, this process requires precise control of the reaction conditions and reagent dosage. Due to the different reaction activities of different halogens, so as to avoid excessive by-products.
Second, the diazotization reaction method. First, aniline is diazotized to form diazonium salts. Subsequently, fluorine, chlorine, and bromine atoms are gradually introduced by nucleophilic substitution reactions of different halogens. For example, fluoroboronic acid is used to treat diazonium salts to obtain fluoroaromatic hydrocarbons; then a suitable chlorination reagent is used to react with diazonium salts to introduce chlorine atoms; Similarly, bromine atoms are introduced. This method requires attention to the mildness of the conditions of the diazotization reaction and the selectivity of the subsequent substitution reaction.
Third, the metal catalytic coupling reaction method. With the help of transition metal catalysts, such as palladium, nickel, etc., the halogen-containing aromatic hydrocarbon halides are coupled with the corresponding halogenating reagents. For example, using bromobenzene as a substrate, in the presence of a palladium catalyst, the chlorine atom is coupled with the chlorination reagent to introduce This kind of method requires high catalyst, and the reaction system needs to be optimized to improve the reaction efficiency and selectivity.
When preparing 1% 2C3% 2C6 - fluorochlorobromobenzene, it is necessary to comprehensively consider the availability of raw materials, the difficulty of reaction conditions, the purity and yield of the product and many other factors to choose the optimal method.
First, it can be used as a key intermediate in pharmaceutical synthesis. In the creation process of many drugs, 1,3,6-fluorobrobenzene can introduce specific functional groups through ingenious chemical reactions to build the basic structure of drug molecules. For example, some compounds with special pharmacological activities need to be initiated by 1,3,6-fluorobrobenzene and go through a multi-step reaction to obtain the expected drug molecules for the treatment of diseases.
Second, it is also indispensable in pesticide synthesis. The research and development of pesticides aims to effectively control crop diseases and pests, and ensure the harvest of agriculture. 1,3,6-fluorobromobenzene can be used as an important raw material to participate in the synthesis of new pesticide varieties. Its unique chemical structure endows pesticides with specific insecticidal, bactericidal or weeding properties, and compared with traditional pesticides, new pesticides may have higher activity and lower environmental toxicity, and are more friendly to the ecological environment.
Furthermore, in the field of materials science, 1,3,6-fluorobromobenzene also has its uses. It can be used to synthesize special polymer materials, giving materials unique properties such as excellent heat resistance, chemical corrosion resistance or optical properties. Such special polymer materials are widely used in high-end fields such as electronics, aerospace, etc., to meet the strict requirements for special properties of materials in related fields.
To sum up, the important uses of 1,3,6-chlorobromobenzene in the fields of medicine, pesticides and materials science play a key role in organic chemistry and related industries, promoting the progress and development of technology in various fields.
Bear the brunt, safety protection is the key. This compound has certain toxicity and irritation, or can cause damage to the human body. Therefore, when using, be sure to wear suitable protective equipment, such as gas masks, protective gloves and protective clothing, to prevent skin contact and respiratory inhalation. And the operation should be carried out in a well-ventilated place, or with the help of ventilation equipment, volatile gaseous substances should be discharged in time to reduce their concentration in the air.
Furthermore, storage should not be underestimated. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources, and away from direct sunlight. It should be stored separately from oxidants, acids, alkalis, etc., and should not be mixed to prevent dangerous chemical reactions. At the same time, the storage area should be equipped with suitable materials to contain leaks.
When using, accurate operation is essential. Strictly follow the established operating procedures and control the reaction conditions, such as temperature, pressure, reaction time, etc. Due to its active chemical properties, the reaction conditions are slightly poor, which may cause the reaction to go out of control and cause adverse consequences. And the residue after use must not be discarded at will, and should be properly handled in accordance with relevant regulations to prevent pollution to the environment.
During transportation, it is also necessary to be cautious. Adhere to relevant transportation regulations, select suitable packaging materials and transportation methods to ensure safety during transportation and prevent leakage accidents caused by packaging damage. In short, when using 1% 2C3% 2C6 - fluorochlorobromobenzene, the above precautions should be fully paid attention to to to ensure personnel safety, environmental safety and smooth operation.

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