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1-(3-Chloropropoxy)-4-Methoxybenzene
Linshang Chemical
|
HS Code |
382260 |
| Chemical Formula | C10H13ClO2 |
| Molecular Weight | 200.66 |
| Appearance | Typically a colorless to pale yellow liquid (assumed based on similar compounds) |
| Solubility In Water | Low solubility, as it is an organic ether with non - polar aromatic and alkoxy groups |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether, and chloroform |
| Odor | May have a characteristic ether - like or slightly aromatic odor |
As an accredited 1-(3-Chloropropoxy)-4-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 1-(3 - chloropropoxy)-4 - methoxybenzene in sealed chemical - grade packaging. |
| Storage | 1-(3 - Chloropropoxy)-4 - methoxybenzene should be stored in a cool, dry, well - ventilated area, away from sources of heat and ignition. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, acids, and bases to prevent chemical reactions. Avoid exposure to sunlight to maintain its stability. |
| Shipping | 1-(3 - Chloropropoxy)-4 - methoxybenzene should be shipped in sealed, corrosion - resistant containers. Ensure compliance with chemical shipping regulations, marking containers clearly for safe and proper handling during transit. |
Competitive 1-(3-Chloropropoxy)-4-Methoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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As a leading 1-(3-Chloropropoxy)-4-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1- (3-chloropropoxy) -4-methoxybenzene?
The main users of 1 - (3 - hydroxyethyl) - 4 - acetaminobenzene are in the pharmaceutical and dye industries.
In the pharmaceutical industry, it is an important raw material. Based on this, a variety of drugs can be prepared. Such as some antipyretic and analgesic agents, this compound participates in the synthesis process. Its structural characteristics make the drug have specific pharmacological activity, which can effectively relieve human pain and fever. In addition, in the preparation of antibacterial drugs, 1 - (3 - hydroxyethyl) - 4 - acetaminobenzene is also useful, which can add antibacterial groups to drug molecules to inhibit or kill specific bacteria.
In the dye industry, it plays a key role. Due to its specific chemical structure and functional group, it can be chemically modified and reacted to produce bright-colored dyes with good fastness. When dyed on fabrics, the color is bright and long-lasting, and it is washable and light-resistant. And according to different needs, by changing the reaction conditions and modification methods, dyes of various hues can be prepared to meet the needs of textile, printing and dyeing industries for color richness.
Therefore, 1- (3-hydroxyethyl) -4-acetamidobenzene, with its unique chemical properties, can not be ignored in the pharmaceutical and dye fields. It has made great contributions to promoting the development of these two industries.
In the pharmaceutical industry, it is an important raw material. Based on this, a variety of drugs can be prepared. Such as some antipyretic and analgesic agents, this compound participates in the synthesis process. Its structural characteristics make the drug have specific pharmacological activity, which can effectively relieve human pain and fever. In addition, in the preparation of antibacterial drugs, 1 - (3 - hydroxyethyl) - 4 - acetaminobenzene is also useful, which can add antibacterial groups to drug molecules to inhibit or kill specific bacteria.
In the dye industry, it plays a key role. Due to its specific chemical structure and functional group, it can be chemically modified and reacted to produce bright-colored dyes with good fastness. When dyed on fabrics, the color is bright and long-lasting, and it is washable and light-resistant. And according to different needs, by changing the reaction conditions and modification methods, dyes of various hues can be prepared to meet the needs of textile, printing and dyeing industries for color richness.
Therefore, 1- (3-hydroxyethyl) -4-acetamidobenzene, with its unique chemical properties, can not be ignored in the pharmaceutical and dye fields. It has made great contributions to promoting the development of these two industries.
What are the physical properties of 1- (3-chloropropoxy) -4-methoxybenzene?
The physical properties of 1- (3-hydroxyethyl) -4-methoxybenzyl are as follows:
This substance is mostly solid at room temperature, looking like a white to light yellow crystalline powder, like fine sand or fine scales, uniform and fine. It has a certain melting point, which is measured to be about [X] ° C. When the temperature rises to this point, the substance gradually melts from solid to liquid, and this process is quite smooth without abnormal phase change.
Its density is about [X] g/cm ³, which is in a certain range compared with the density of common organic compounds. When placed in water, it is difficult to dissolve in water due to its hydrophobicity, just like particles floating on water, and it is difficult to dissolve with water. However, in organic solvents, such as ethanol, ether, etc., it has good solubility and can quickly diffuse to form a uniform solution with the solvent.
This compound has low volatility and is left in the air for a long time at room temperature and pressure, with little mass loss. Its stability to light and heat is also characterized. Moderate light exposure and heating do not cause significant changes in its chemical structure and physical form in a short period of time. However, if it is irradiated with strong light for a long time or baked at high temperature, it will also cause decomposition or deterioration.
It has a certain hardness and brittleness in the solid state, and can be easily broken when struck by a hard object. The shape and size of the pieces are irregular. The powder is twisted in the hand, and it feels delicate to the touch, without roughness or prickness. In addition, under specific conditions, this object can exhibit a crystal structure. The shape of the crystal is regular and has a certain symmetry. Viewed through a microscope, its crystal structure is clearly discernible and beautiful, showing the subtlety of natural creations.
This substance is mostly solid at room temperature, looking like a white to light yellow crystalline powder, like fine sand or fine scales, uniform and fine. It has a certain melting point, which is measured to be about [X] ° C. When the temperature rises to this point, the substance gradually melts from solid to liquid, and this process is quite smooth without abnormal phase change.
Its density is about [X] g/cm ³, which is in a certain range compared with the density of common organic compounds. When placed in water, it is difficult to dissolve in water due to its hydrophobicity, just like particles floating on water, and it is difficult to dissolve with water. However, in organic solvents, such as ethanol, ether, etc., it has good solubility and can quickly diffuse to form a uniform solution with the solvent.
This compound has low volatility and is left in the air for a long time at room temperature and pressure, with little mass loss. Its stability to light and heat is also characterized. Moderate light exposure and heating do not cause significant changes in its chemical structure and physical form in a short period of time. However, if it is irradiated with strong light for a long time or baked at high temperature, it will also cause decomposition or deterioration.
It has a certain hardness and brittleness in the solid state, and can be easily broken when struck by a hard object. The shape and size of the pieces are irregular. The powder is twisted in the hand, and it feels delicate to the touch, without roughness or prickness. In addition, under specific conditions, this object can exhibit a crystal structure. The shape of the crystal is regular and has a certain symmetry. Viewed through a microscope, its crystal structure is clearly discernible and beautiful, showing the subtlety of natural creations.
What are the chemical properties of 1- (3-chloropropoxy) -4-methoxybenzene?
The chemical properties of 1- (3-hydroxyethyl) -4-methoxybenzyl are as follows:
In this compound, there are a variety of functional groups, which have an important impact on its chemical properties.
First of all, the hydroxyl group in the hydroxyethyl group has a certain activity. The hydroxyl group can participate in the esterification reaction. When co-heated with carboxylic acid under acid-catalyzed conditions, the esterification reaction can occur to form the corresponding ester compound. This process is that the hydrogen atom in the hydroxyl group is replaced by an acyl group. For example, under the catalysis and heating conditions of concentrated sulfuric acid with acetic acid, hydroxyethyl acetate derivatives are formed. Concentrated sulfuric acid plays a catalytic and water-absorbing role in this reaction, promoting the reaction to the direction of ester formation.
Hydroxyl groups are also prone to oxidation reactions. Under the action of mild oxidizing agents such as manganese dioxide, it can be oxidized to an aldehyde group; if stronger oxidizing agents such as potassium permanganate are used, it may be further oxidized to a carboxyl group.
The methoxybenzyl moiety, where the methoxy group is the donator group, will increase the electron cloud density on the benzene ring, thereby enhancing the electrophilic substitution reaction activity of the benzene ring. In halogenation reactions, such as with bromine catalyzed by iron or iron tribromide, bromine atoms will preferentially replace the hydrogen atoms at the o and para sites of the methoxy group on the benzene ring to generate corresponding halogenated products. This is because the donator effect of the methoxy group makes the o and para electron cloud density relatively higher, making it more vulnerable to attack by electrophilic reagents.
In addition, the carbon-carbon single bond between benzyl and benzene ring can undergo benzyl radical reaction under certain conditions. For example, under the initiation of light or peroxide, the radical substitution reaction occurs with hydrogen bromide and other reagents, and the hydrogen atom on the benzyl carbon is replaced by the bromine atom.
In summary, 1- (3-hydroxyethyl) -4-methoxybenzyl has rich chemical properties due to the functional groups it contains, and can participate in various types of chemical reactions, which has important application value in the field of organic synthesis.
In this compound, there are a variety of functional groups, which have an important impact on its chemical properties.
First of all, the hydroxyl group in the hydroxyethyl group has a certain activity. The hydroxyl group can participate in the esterification reaction. When co-heated with carboxylic acid under acid-catalyzed conditions, the esterification reaction can occur to form the corresponding ester compound. This process is that the hydrogen atom in the hydroxyl group is replaced by an acyl group. For example, under the catalysis and heating conditions of concentrated sulfuric acid with acetic acid, hydroxyethyl acetate derivatives are formed. Concentrated sulfuric acid plays a catalytic and water-absorbing role in this reaction, promoting the reaction to the direction of ester formation.
Hydroxyl groups are also prone to oxidation reactions. Under the action of mild oxidizing agents such as manganese dioxide, it can be oxidized to an aldehyde group; if stronger oxidizing agents such as potassium permanganate are used, it may be further oxidized to a carboxyl group.
The methoxybenzyl moiety, where the methoxy group is the donator group, will increase the electron cloud density on the benzene ring, thereby enhancing the electrophilic substitution reaction activity of the benzene ring. In halogenation reactions, such as with bromine catalyzed by iron or iron tribromide, bromine atoms will preferentially replace the hydrogen atoms at the o and para sites of the methoxy group on the benzene ring to generate corresponding halogenated products. This is because the donator effect of the methoxy group makes the o and para electron cloud density relatively higher, making it more vulnerable to attack by electrophilic reagents.
In addition, the carbon-carbon single bond between benzyl and benzene ring can undergo benzyl radical reaction under certain conditions. For example, under the initiation of light or peroxide, the radical substitution reaction occurs with hydrogen bromide and other reagents, and the hydrogen atom on the benzyl carbon is replaced by the bromine atom.
In summary, 1- (3-hydroxyethyl) -4-methoxybenzyl has rich chemical properties due to the functional groups it contains, and can participate in various types of chemical reactions, which has important application value in the field of organic synthesis.
What are the synthesis methods of 1- (3-chloropropoxy) -4-methoxybenzene?
The synthesis of 1- (3-hydroxyethyl) -4-acetaminonaphthalene is an important topic in the field of organic synthesis. To synthesize this substance, there are several common methods:
First, naphthalene is used as the starting material. The naphthalene is first introduced into the acetamino group through a specific reaction. This process requires precise control of the reaction conditions, such as temperature and reactant ratio, to ensure that the acetamino group is connected at the appropriate position. Then, through a series of reactions, the (3-hydroxyethyl) group is introduced at the appropriate position. In this path, each step of the reaction needs to be handled with caution. Due to the special structure of naphthalene, the selectivity of the reaction needs to be carefully considered, otherwise side reactions will easily occur and the product will be impure.
Second, the naphthalene derivative containing a specific substituent can be selected as the starting material. If the starting material already contains some groups of the target structure, the reaction steps can be reduced and the synthesis efficiency can be improved. For example, if the starting material already contains acetamide, only the introduction of the (3-hydroxyethyl) group needs to be focused. However, finding suitable substituted naphthalene derivatives is not easy, or needs to be prepared in advance through multi-step reactions, and the cost and source of such starting materials need to be taken into account.
Third, the strategy of gradually building the carbon chain is adopted. Small molecular fragments containing (3-hydroxyethyl) and acetamido are synthesized separately, and then the two are connected to the naphthalene ring through a carbon-carbon bond reaction. This strategy is more flexible, and suitable reactions and reagents can be selected according to actual conditions to optimize the reaction path. However, this process involves multiple steps, and the control of the total yield of the reaction is crucial. The separation and purification of intermediates between each step of the reaction also need to be carefully designed to ensure the quality and purity of the final product.
There are various methods for synthesizing 1- (3-hydroxyethyl) -4-acetamido naphthalene, each with its own advantages and disadvantages. In actual synthesis, it is necessary to comprehensively consider the availability of raw materials, cost, difficulty of reaction conditions, product purity and yield, and carefully select the appropriate synthesis route to achieve the goal of efficient, economical and high-quality synthesis.
First, naphthalene is used as the starting material. The naphthalene is first introduced into the acetamino group through a specific reaction. This process requires precise control of the reaction conditions, such as temperature and reactant ratio, to ensure that the acetamino group is connected at the appropriate position. Then, through a series of reactions, the (3-hydroxyethyl) group is introduced at the appropriate position. In this path, each step of the reaction needs to be handled with caution. Due to the special structure of naphthalene, the selectivity of the reaction needs to be carefully considered, otherwise side reactions will easily occur and the product will be impure.
Second, the naphthalene derivative containing a specific substituent can be selected as the starting material. If the starting material already contains some groups of the target structure, the reaction steps can be reduced and the synthesis efficiency can be improved. For example, if the starting material already contains acetamide, only the introduction of the (3-hydroxyethyl) group needs to be focused. However, finding suitable substituted naphthalene derivatives is not easy, or needs to be prepared in advance through multi-step reactions, and the cost and source of such starting materials need to be taken into account.
Third, the strategy of gradually building the carbon chain is adopted. Small molecular fragments containing (3-hydroxyethyl) and acetamido are synthesized separately, and then the two are connected to the naphthalene ring through a carbon-carbon bond reaction. This strategy is more flexible, and suitable reactions and reagents can be selected according to actual conditions to optimize the reaction path. However, this process involves multiple steps, and the control of the total yield of the reaction is crucial. The separation and purification of intermediates between each step of the reaction also need to be carefully designed to ensure the quality and purity of the final product.
There are various methods for synthesizing 1- (3-hydroxyethyl) -4-acetamido naphthalene, each with its own advantages and disadvantages. In actual synthesis, it is necessary to comprehensively consider the availability of raw materials, cost, difficulty of reaction conditions, product purity and yield, and carefully select the appropriate synthesis route to achieve the goal of efficient, economical and high-quality synthesis.
What should be paid attention to when storing and transporting 1- (3-chloropropoxy) -4-methoxybenzene?
When storing and transporting 1- (3-hydroxyethyl) -4-methoxybenzene, the following aspects should be paid attention to.
First, the storage place should be selected in a cool and dry place. This substance is quite sensitive to temperature and humidity, and high temperature and humidity can easily cause its properties to change. If the storage environment temperature is too high, it may cause its decomposition reaction, which in turn affects the quality; and if the humidity is too high, moisture may react with it, or impurities may be mixed into it. For example, the ancients stored precious herbs, and they also chose dry and ventilated warehouses to prevent mildew and rot.
Second, keep away from fire sources and oxidants. This compound has a certain flammability. Once it encounters an open flame, it is very easy to ignite a raging fire, and the oxidant will react violently with it, greatly increasing the risk of fire and explosion. Just like the ancient Hyogo, flammable substances such as gunpowder must be kept away from fire sources and strong oxidants to ensure safety.
Third, the storage container must be well sealed. This is to avoid contact with oxygen, moisture and other components in the air. Because many components in the air will react with the substance such as oxidation, resulting in deterioration. Just like the ancients sealed the wine jar to store good wine, so that its fragrance and quality will not be lost.
Fourth, the transportation process should prevent violent vibration and collision. Violent vibration and collision may cause damage to the packaging and allow substances to leak. And the energy generated by vibration and friction may also trigger chemical reactions. Just like when transporting porcelain in ancient times, it needs to be properly wrapped in soft objects and handled with care to prevent damage.
Fifth, relevant transportation regulations and standards must be followed. Different regions and different transportation methods have specific requirements and must be strictly operated in accordance with regulations. This is just like walking on the road in ancient times. Different counties have different laws and must abide by them in order to travel unimpeded. In short, when storing and transporting 1- (3-hydroxyethyl) -4-methoxybenzene, the above details should not be taken lightly, so as to ensure its safety and quality.
First, the storage place should be selected in a cool and dry place. This substance is quite sensitive to temperature and humidity, and high temperature and humidity can easily cause its properties to change. If the storage environment temperature is too high, it may cause its decomposition reaction, which in turn affects the quality; and if the humidity is too high, moisture may react with it, or impurities may be mixed into it. For example, the ancients stored precious herbs, and they also chose dry and ventilated warehouses to prevent mildew and rot.
Second, keep away from fire sources and oxidants. This compound has a certain flammability. Once it encounters an open flame, it is very easy to ignite a raging fire, and the oxidant will react violently with it, greatly increasing the risk of fire and explosion. Just like the ancient Hyogo, flammable substances such as gunpowder must be kept away from fire sources and strong oxidants to ensure safety.
Third, the storage container must be well sealed. This is to avoid contact with oxygen, moisture and other components in the air. Because many components in the air will react with the substance such as oxidation, resulting in deterioration. Just like the ancients sealed the wine jar to store good wine, so that its fragrance and quality will not be lost.
Fourth, the transportation process should prevent violent vibration and collision. Violent vibration and collision may cause damage to the packaging and allow substances to leak. And the energy generated by vibration and friction may also trigger chemical reactions. Just like when transporting porcelain in ancient times, it needs to be properly wrapped in soft objects and handled with care to prevent damage.
Fifth, relevant transportation regulations and standards must be followed. Different regions and different transportation methods have specific requirements and must be strictly operated in accordance with regulations. This is just like walking on the road in ancient times. Different counties have different laws and must abide by them in order to travel unimpeded. In short, when storing and transporting 1- (3-hydroxyethyl) -4-methoxybenzene, the above details should not be taken lightly, so as to ensure its safety and quality.
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