1,3-Dichloro-2-Fluoro-5-(3,3,3-Trifluoroprop-1-En-2-Yl)Benzene
Linshang Chemical
HS Code |
919398 |
Chemical Formula | C9H4Cl2F4 |
Molecular Weight | 260.927 g/mol |
Appearance | Unknown |
Physical State | Unknown |
Boiling Point | Unknown |
Melting Point | Unknown |
Density | Unknown |
Solubility In Water | Unknown |
Vapor Pressure | Unknown |
Flash Point | Unknown |
As an accredited 1,3-Dichloro-2-Fluoro-5-(3,3,3-Trifluoroprop-1-En-2-Yl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500g of 1,3 - dichloro - 2 - fluoro - 5 - (3,3,3 - trifluoroprop - 1 - en - 2 - yl)benzene in sealed chemical drum. |
Storage | 1,3 - dichloro - 2 - fluoro - 5 - (3,3,3 - trifluoroprop - 1 - en - 2 - yl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and incompatible substances. Store in a tightly sealed container to prevent leakage and vapor release. Avoid storing near oxidizing agents and reactive chemicals to ensure safety. |
Shipping | 1,3 - dichloro - 2 - fluoro - 5 - (3,3,3 - trifluoroprop - 1 - en - 2 - yl)benzene is shipped in specialized, sealed containers. Transport follows strict chemical safety regulations to prevent spills and ensure safe delivery to the intended destination. |
Competitive 1,3-Dichloro-2-Fluoro-5-(3,3,3-Trifluoroprop-1-En-2-Yl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 1,3-Dichloro-2-Fluoro-5-(3,3,3-Trifluoroprop-1-En-2-Yl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In the field of pharmacy, the special alkynyl, chloroalkyl and naphthalene ring structures in its structure give unique chemical activity. Alkynyl groups can often participate in a variety of chemical reactions, or can be modified to enhance affinity for specific biological targets, used to develop new drugs, such as antibacterial, anti-inflammatory or anti-tumor active agents. In the past, doctors searched for drugs, and often explored the relationship between the structure and activity of substances. With the characteristics of this structure, it may become a new source of drugs.
In material science, naphthalene rings provide a rigid structure, and chloroalkyl groups can change the solubility and thermal stability of compounds. It can be used to prepare high-performance polymer materials, such as engineering plastics that are resistant to high temperature and chemical corrosion, or to optimize the electrical properties of materials for electronic devices. Although there was no concept of materials science in ancient times, the pursuit of material properties was in the same vein in the manufacture of durable appliances, fabric treatment and other processes. If this material was known at that time, it could be used to improve material quality.
In addition, because it contains unsaturated bonds and special substituents, it can be used as an intermediate in organic synthesis. Organic synthesis is like the ingenuity of ancient craftsmen, splicing atoms and groups in sequence to form complex molecules. With this material as the starting material, more complex and functional organic compounds can be constructed through reactions such as addition and substitution, which can be used in fragrances, dyes and other industries. For example, in ancient dyeing workshops, in order to obtain bright and long-lasting colors, new dyeing raw materials and processes are constantly being explored. This material may play a role in dye synthesis.
Under normal temperature and pressure, it is often colorless to light yellow liquid, with a clear appearance, and its texture can be seen as uniform, without suspension or precipitation. This color state is easy to observe and distinguish in many application scenarios.
Smell, has a special smell, but this smell is not simply fragrant, but a unique chemical smell. This smell can be used as an important clue to perceive its existence when operating and using.
degree, the density is higher than that of water. If it is placed in the same container as water, it can be seen that it sinks to the bottom of the water. This characteristic has a great impact on the separation, storage and transportation process. It is necessary to choose the appropriate container and operation method according to its density characteristics.
In the case of melting and boiling, the melting point is relatively low, and it is liquid at or near room temperature. The boiling point is higher, and it needs to reach a certain temperature to boil into a gaseous state. This boiling point characteristic determines its physical form at different temperatures. When heating or cooling, the temperature needs to be strictly controlled to meet specific process requirements. In organic solvents, such as common ethanol, ether, etc., it exhibits good solubility and can dissolve with it to form a uniform solution. However, in water, the solubility is extremely low and almost insoluble. This solubility property is crucial for the selection of solvents in the fields of chemical synthesis, purification, and analytical testing.
Its chemical properties are the first to recommend stability. Because it contains multiple fluorine atoms, the carbon-fluorine bond energy is quite high, which makes the compound structure stable and difficult to undergo chemical reactions under normal conditions. If it is stored at room temperature and pressure, it can be stored for a long time and will not be easily decomposed or deteriorated.
Furthermore, the compound has a certain polarity. The electronegativity of fluorine and chlorine atoms is large, which makes the molecular charge distribution uneven and shows polarity. This polarity affects its solubility. In polar solvents, the solubility is better than that of non-polar solvents. In solution, there are strong interactions with other polar molecules, which affect their reactivity and selectivity.
In terms of reactivity, due to the presence of alkynyl groups, many characteristic reactions of alkynyl groups can occur. If nucleophilic addition reactions occur with nucleophiles, the alkynyl tribonds are electron-rich and vulnerable to attack by nucleophiles, generating new carbon-carbon or carbon-hetero atomic bonds, which provide a way to construct complex organic molecular structures.
In addition, substituents on the benzene ring affect the electron cloud density of the benzene ring and the selectivity of the reaction check point. The electron-absorbing action of chlorine and fluorine atoms decreases the electron cloud density of the benzene ring, and the electrophilic substitution reaction activity decreases, and the substituent localization effect determines the position of the newly introduced group on the benzene ring, which is of great significance for the design of organic synthesis routes.
In the field of materials science, its stability and unique electronic properties may be used to prepare high-performance materials; in medicinal chemistry, its polarity and reactivity may endow drugs with specific physiological activities and pharmacokinetic properties.
First take an appropriate amount of butene, place it in a clean reactor, control the temperature in a specific range, usually slightly hot, about 30 to 40 degrees Celsius. Slowly inject the bromine-containing reagent, which needs to be pre-refined to remove its impurities to ensure the purity of the reaction. When implanting, when the bromine and butene are fully contacted at a constant speed and slowly, a substitution reaction occurs. In this process, pay close attention to the changes in the reaction kettle, observe the changes in its color and temperature, and fine-tune the conditions in a timely manner. After an hour, 1,3-dibromo-2-butene can be obtained.
Then, prepare 3,3,3-tribromopropylene-1-alkyne-2-based reagents. Take propane as the base, use liquid ammonia as the solvent, and cool it to negative 30 to 40 degrees Celsius to create a low temperature environment. Add an appropriate amount of brominating agent, and the ratio of brominating agent should be accurate. Generally, the molar ratio of propane to brominating agent is about 1:3.5. In the reaction, stirring is continued to make the two fully blend. For about two hours, a 3,3,3-tribromopropylene-1-alkyne-2-based intermediate can be obtained.
Finally, the obtained 1,3-dibromo-2-butene and 3,3,3-tribromopropylene-1-alkyne-2-based intermediates are placed in an organic solvent. This solvent should be selected from dichloromethane, which has good solubility and stable properties. Add an appropriate amount of catalyst, such as palladium catalyst, and the catalyst amount is about 2% - 3% of the total reactants. The temperature is raised to 60 to 70 degrees Celsius, and the reflux reaction is about three hours. After the reaction is completed, the product is purified through extraction, washing, drying, distillation and other processes, and the final product is 1% 2C3-dibromo-2-butene-5- (3,3,3-tribromopropyl-1-alkyne-2-yl) benzene. Each step needs to strictly abide by the operating procedures and carefully control the conditions to obtain high-purity products.
First, safety protection must be comprehensive. This chemical is highly toxic and protective equipment is indispensable during operation. Wear tight protective clothing, which can effectively prevent it from contacting the skin and avoid absorption of poisoning; wear protective blindfolds, because if accidentally splashed into the eyes, the consequences can be unimaginable, can cause serious damage to the eye tissue, and even blindness; equipped with gas masks is also very critical, which can filter the substance in the air to prevent inhalation from poisoning. After all, inhalation poisoning is extremely hidden and harmful.
Second, the operating environment requirements are strict. It needs to be operated in a well-ventilated place, which can quickly disperse volatile chemicals, reduce the concentration in the air, and reduce the risk of poisoning. At the same time, keep away from fire and heat sources, because the substance may be flammable, in case of open flames, hot topics, or cause combustion or even explosion, resulting in serious safety accidents.
Third, storage conditions should not be sloppy. It should be stored in a cool, dry and well-ventilated place, and it should be stored separately from oxidants and acids. Due to improper mixing or chemical reactions, the stability is lost, and toxic gases are released or other hazards are caused. Storage containers should also be well sealed to prevent leakage.
Fourth, emergency treatment must be aware. In the event of a leak, personnel should quickly evacuate to a safe area and strictly restrict the entry of unrelated personnel. Emergency responders must wear professional protective equipment to avoid self-poisoning. A small amount of leakage can be absorbed by inert materials such as sand and vermiculite; if a large amount of leakage occurs, it needs to be built into a dike or dug for containment, and then treated by appropriate methods. If you accidentally come into contact with the skin, you should immediately remove the contaminated clothes and rinse with a large amount of flowing water; if it splashes into the eyes, you should immediately lift the eyelids, rinse with flowing water or normal saline, and seek medical attention in time. If inhaled, you should quickly move to a fresh air place to keep the respiratory tract unobstructed. If you have breathing difficulties, give oxygen, stop breathing, and immediately perform artificial respiration and seek medical attention.

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