Linshang Chemical
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1,3-Dichloro-2-(Trifluoromethyl)Benzene
Linshang Chemical
|
HS Code |
403423 |
| Chemical Formula | C7H3Cl2F3 |
| Molecular Weight | 215.00 |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 166 - 168 °C |
| Density | 1.45 g/cm³ |
| Solubility | Insoluble in water, soluble in organic solvents |
| Flash Point | 56 °C |
| Refractive Index | 1.456 - 1.458 |
| Stability | Stable under normal conditions |
As an accredited 1,3-Dichloro-2-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1,3 - Dichloro - 2-(trifluoromethyl)benzene in 5 - liter sealed drums for chemical storage. |
| Storage | 1,3 - Dichloro - 2-(trifluoromethyl)benzene should be stored in a cool, well - ventilated area, away from direct sunlight and heat sources. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like stainless steel or certain plastics. Store it separate from oxidizing agents, reducing agents, and reactive chemicals to prevent potential reactions. |
| Shipping | 1,3 - Dichloro - 2 - (trifluoromethyl)benzene is shipped in specialized, tightly - sealed containers compliant with chemical transport regulations. Transport is carefully monitored to ensure safe transit due to its chemical nature. |
Competitive 1,3-Dichloro-2-(Trifluoromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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As a leading 1,3-Dichloro-2-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1,3-dichloro-2- (trifluoromethyl) benzene?
1,3-Dichloro-2 - (triethoxymethyl) benzene, which is widely used. In the field of medicinal chemistry, it is a key intermediate. It can be converted into pharmaceutical ingredients with specific biological activities through a series of chemical reactions and delicate steps, contributing extraordinary power to human healing and disease.
In the field of materials science, it plays a unique role. It can be used as a raw material for the synthesis of special functional polymer materials, endowing materials with excellent properties such as excellent stability and unique optical properties, which are widely used in advanced material preparation processes and promote the progress of materials science.
In the field of organic synthesis, it is like a master key. With its special chemical structure, it can participate in various types of organic reactions, enabling chemists to build complex and novel organic molecular structures, opening up a broader space for the development of organic synthetic chemistry. It also occupies an important position in the fine chemical industry and is used to manufacture high-end fine chemicals, such as special fragrances and high-performance coating additives, which play a key role in improving product quality and performance.
In the field of materials science, it plays a unique role. It can be used as a raw material for the synthesis of special functional polymer materials, endowing materials with excellent properties such as excellent stability and unique optical properties, which are widely used in advanced material preparation processes and promote the progress of materials science.
In the field of organic synthesis, it is like a master key. With its special chemical structure, it can participate in various types of organic reactions, enabling chemists to build complex and novel organic molecular structures, opening up a broader space for the development of organic synthetic chemistry. It also occupies an important position in the fine chemical industry and is used to manufacture high-end fine chemicals, such as special fragrances and high-performance coating additives, which play a key role in improving product quality and performance.
What are the physical properties of 1,3-dichloro-2- (trifluoromethyl) benzene?
1% 2C3-dihydro-2- (triethoxy methyl) naphthalene is a kind of organic compound. Its physical properties are particularly important and are related to the many uses and characteristics of this substance.
This compound is mostly solid at room temperature. Looking at its appearance, it may be a white to light yellow crystalline powder with a fine and uniform texture. Its melting point is also a key physical property. After measurement, specific values can be obtained. This value is of great significance for the maintenance and transformation of its state under different temperature environments. The melting point is established, and at a specific temperature, the substance melts from a solid state to a liquid state. This temperature limit has a great impact on its processing and application.
Furthermore, its solubility cannot be ignored. In organic solvents, such as ethanol, ether, etc., or exhibit good solubility. This property allows it to be fully mixed with other organic reagents when used in organic synthesis and other fields to promote the smooth progress of the reaction. However, in water, its solubility or poor, due to the molecular structure of the compound, the force between it and water molecules is weak.
In addition, the density of 1% 2C3-dihydro-2- (triethoxy methyl) naphthalene is also one of its physical properties. Accurate determination of its density can help to understand its proportion and distribution in the mixture. The value of density can provide key parameters for chemical production, storage and transportation, etc., to ensure the safety and efficiency of the operation process.
As for its volatility, it is relatively low. The non-volatile characteristics ensure the stability of the substance during storage and use, reducing losses caused by volatilization and potential safety risks.
This compound is mostly solid at room temperature. Looking at its appearance, it may be a white to light yellow crystalline powder with a fine and uniform texture. Its melting point is also a key physical property. After measurement, specific values can be obtained. This value is of great significance for the maintenance and transformation of its state under different temperature environments. The melting point is established, and at a specific temperature, the substance melts from a solid state to a liquid state. This temperature limit has a great impact on its processing and application.
Furthermore, its solubility cannot be ignored. In organic solvents, such as ethanol, ether, etc., or exhibit good solubility. This property allows it to be fully mixed with other organic reagents when used in organic synthesis and other fields to promote the smooth progress of the reaction. However, in water, its solubility or poor, due to the molecular structure of the compound, the force between it and water molecules is weak.
In addition, the density of 1% 2C3-dihydro-2- (triethoxy methyl) naphthalene is also one of its physical properties. Accurate determination of its density can help to understand its proportion and distribution in the mixture. The value of density can provide key parameters for chemical production, storage and transportation, etc., to ensure the safety and efficiency of the operation process.
As for its volatility, it is relatively low. The non-volatile characteristics ensure the stability of the substance during storage and use, reducing losses caused by volatilization and potential safety risks.
What are the chemical properties of 1,3-dichloro-2- (trifluoromethyl) benzene?
1% 2C3 -dibromo-2- (triethoxy methyl) benzene-based organic compounds have unique chemical properties.
In this compound, bromine atoms are active and can participate in nucleophilic substitution reactions. Under suitable conditions, nucleophilic reagents such as alkoxides, amines, etc., can attack the carbon atoms connected to bromine, so that bromine atoms are replaced to form new organic compounds.
Triethoxy methyl part, the ethoxy group has certain stability, but under acidic conditions, the ethoxy group can be protonated, which can lead to ether bond breaking. At this time, the compound may undergo hydrolysis reaction, and the ethoxy group is gradually replaced by the hydroxyl group to form a hydroxyl-containing derivative.
At the same time, the benzene ring imparts aromaticity to the compound, enabling it to carry out aromatic electrophilic substitution reactions. For example, under suitable catalyst and reaction conditions, the benzene ring can react with electrophilic reagents such as halogenating agents, nitrifying agents, etc., and the corresponding substituents are introduced on the benzene ring.
In addition, the chemical properties of the compound are also affected by factors such as reaction temperature, solvent, and concentration of reactants. When the temperature increases, the reaction rate is usually accelerated, but excessive temperature may lead to side reactions. Polarity and solubility of different solvents also affect the reaction activity and selectivity. In the field of organic synthesis, a full understanding of its chemical properties is helpful to rationally design the reaction route and achieve efficient preparation of the target product.
In this compound, bromine atoms are active and can participate in nucleophilic substitution reactions. Under suitable conditions, nucleophilic reagents such as alkoxides, amines, etc., can attack the carbon atoms connected to bromine, so that bromine atoms are replaced to form new organic compounds.
Triethoxy methyl part, the ethoxy group has certain stability, but under acidic conditions, the ethoxy group can be protonated, which can lead to ether bond breaking. At this time, the compound may undergo hydrolysis reaction, and the ethoxy group is gradually replaced by the hydroxyl group to form a hydroxyl-containing derivative.
At the same time, the benzene ring imparts aromaticity to the compound, enabling it to carry out aromatic electrophilic substitution reactions. For example, under suitable catalyst and reaction conditions, the benzene ring can react with electrophilic reagents such as halogenating agents, nitrifying agents, etc., and the corresponding substituents are introduced on the benzene ring.
In addition, the chemical properties of the compound are also affected by factors such as reaction temperature, solvent, and concentration of reactants. When the temperature increases, the reaction rate is usually accelerated, but excessive temperature may lead to side reactions. Polarity and solubility of different solvents also affect the reaction activity and selectivity. In the field of organic synthesis, a full understanding of its chemical properties is helpful to rationally design the reaction route and achieve efficient preparation of the target product.
What are the synthesis methods of 1,3-dichloro-2- (trifluoromethyl) benzene?
The synthesis of 1% 2C3 -dibromo-2- (triethoxy methyl) benzene involves many delicate methods and is an important issue in the field of organic synthesis.
One of them can be derived from benzaldehyde derivatives. First, benzaldehyde is introduced into the triethoxy methyl group through a specific reaction. This step may require a suitable alkaline environment. The reaction of triethoxy methane with benzaldehyde under the action of a catalyst, such as Lewis acid, can promote the condensation reaction of the two to generate the corresponding 2 - (triethoxy methyl) benzaldehyde. Subsequently, for this product, a bromination reaction is carried out under the action of a brominating agent. Commonly used brominating reagents such as liquid bromine, in suitable solvents such as dichloromethane, at low temperatures and in the presence of catalysts (such as iron powder or iron tribromide), bromine atoms can be precisely introduced at the 1,3 positions of the benzene ring, so as to obtain the target product 1% 2C3 -dibromo-2- (triethoxymethyl) benzene.
Second, halobenzene can also be started from halobenzene. First, the halobenzene is metallized, for example, it interacts with reagents such as butyl lithium to form a phenyl metal reagent. Then a nucleophilic substitution reaction occurs with triethoxymethyl halide to construct a 2- (triethoxymethyl) halobenzene intermediate. This intermediate is then brominated, and under suitable conditions, the purpose of introducing bromine atoms at the 1,3 positions of the benzene ring can also be achieved, and finally 1% 2C3 -dibromo-2- (triethoxymethyl) benzene is successfully synthesized.
Furthermore, phenolic compounds can also be considered as starting materials. Phenols are etherified to convert hydroxyl groups into triethoxymethoxy groups, and then selectively introduce bromine atoms at the 1,3 positions of the benzene ring through halogenation reaction, which can also achieve the synthesis of the target product. This process requires fine control of reaction conditions, such as temperature, reagent dosage, reaction time, etc., to ensure that the reaction proceeds efficiently and selectively, and to achieve effective synthesis of 1% 2C3-dibromo-2- (triethoxymethyl) benzene.
One of them can be derived from benzaldehyde derivatives. First, benzaldehyde is introduced into the triethoxy methyl group through a specific reaction. This step may require a suitable alkaline environment. The reaction of triethoxy methane with benzaldehyde under the action of a catalyst, such as Lewis acid, can promote the condensation reaction of the two to generate the corresponding 2 - (triethoxy methyl) benzaldehyde. Subsequently, for this product, a bromination reaction is carried out under the action of a brominating agent. Commonly used brominating reagents such as liquid bromine, in suitable solvents such as dichloromethane, at low temperatures and in the presence of catalysts (such as iron powder or iron tribromide), bromine atoms can be precisely introduced at the 1,3 positions of the benzene ring, so as to obtain the target product 1% 2C3 -dibromo-2- (triethoxymethyl) benzene.
Second, halobenzene can also be started from halobenzene. First, the halobenzene is metallized, for example, it interacts with reagents such as butyl lithium to form a phenyl metal reagent. Then a nucleophilic substitution reaction occurs with triethoxymethyl halide to construct a 2- (triethoxymethyl) halobenzene intermediate. This intermediate is then brominated, and under suitable conditions, the purpose of introducing bromine atoms at the 1,3 positions of the benzene ring can also be achieved, and finally 1% 2C3 -dibromo-2- (triethoxymethyl) benzene is successfully synthesized.
Furthermore, phenolic compounds can also be considered as starting materials. Phenols are etherified to convert hydroxyl groups into triethoxymethoxy groups, and then selectively introduce bromine atoms at the 1,3 positions of the benzene ring through halogenation reaction, which can also achieve the synthesis of the target product. This process requires fine control of reaction conditions, such as temperature, reagent dosage, reaction time, etc., to ensure that the reaction proceeds efficiently and selectively, and to achieve effective synthesis of 1% 2C3-dibromo-2- (triethoxymethyl) benzene.
What are the precautions for using 1,3-dichloro-2- (trifluoromethyl) benzene?
1% 2C3 -dideuterium-2- (triethoxy methyl) silicon should pay attention to the following matters during use:
First, this substance is chemically active. When storing and using it, avoid contact with strong oxidants, strong acids, strong bases and other substances that are prone to chemical reactions. If it comes into contact with each other, it may trigger violent reactions and cause hazards such as combustion and explosion.
Second, because it contains special atoms and groups, it may be sensitive to air and moisture. When storing, ensure that the container is tightly closed and stored in a dry, cool and well-ventilated place to prevent it from reacting with water vapor in the air and other ingredients, resulting in deterioration and affecting its performance and quality.
Third, when taking the substance, it is necessary to follow strict operating procedures. Experimenters need appropriate protective equipment, such as protective gloves, goggles, lab clothes, etc., to prevent them from coming into contact with the skin and eyes. If they come into contact accidentally, they should immediately rinse with a large amount of water and seek medical attention in time according to the actual situation.
Fourth, during use, the reaction conditions must be precisely controlled. Factors such as temperature, pressure, and reaction time may have a significant impact on the process and results of chemical reactions containing the substance. For example, if the temperature is too high or too low, the reaction rate may be abnormal, and even the desired reaction effect cannot be achieved.
Fifth, after use, the remaining substances and related waste must be properly disposed of in accordance with regulations. It should not be discarded at will. It should be disposed of in a suitable manner according to its chemical characteristics to avoid pollution and harm to the environment.
First, this substance is chemically active. When storing and using it, avoid contact with strong oxidants, strong acids, strong bases and other substances that are prone to chemical reactions. If it comes into contact with each other, it may trigger violent reactions and cause hazards such as combustion and explosion.
Second, because it contains special atoms and groups, it may be sensitive to air and moisture. When storing, ensure that the container is tightly closed and stored in a dry, cool and well-ventilated place to prevent it from reacting with water vapor in the air and other ingredients, resulting in deterioration and affecting its performance and quality.
Third, when taking the substance, it is necessary to follow strict operating procedures. Experimenters need appropriate protective equipment, such as protective gloves, goggles, lab clothes, etc., to prevent them from coming into contact with the skin and eyes. If they come into contact accidentally, they should immediately rinse with a large amount of water and seek medical attention in time according to the actual situation.
Fourth, during use, the reaction conditions must be precisely controlled. Factors such as temperature, pressure, and reaction time may have a significant impact on the process and results of chemical reactions containing the substance. For example, if the temperature is too high or too low, the reaction rate may be abnormal, and even the desired reaction effect cannot be achieved.
Fifth, after use, the remaining substances and related waste must be properly disposed of in accordance with regulations. It should not be discarded at will. It should be disposed of in a suitable manner according to its chemical characteristics to avoid pollution and harm to the environment.
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