1,3-Dichloro-5-(3,3,3-Trifluoroprop-1-En-2-Yl)Benzene
Linshang Chemical
HS Code |
507420 |
Chemical Formula | C11H5Cl2F3 |
Molecular Weight | 283.06 |
As an accredited 1,3-Dichloro-5-(3,3,3-Trifluoroprop-1-En-2-Yl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 1 kg of 1,3 - dichloro - 5-(3,3,3 - trifluoroprop - 1 - en - 2 - yl)benzene in sealed chemical - grade container. |
Storage | 1,3 - dichloro - 5 - (3,3,3 - trifluoroprop - 1 - en - 2 - yl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from sources of heat, ignition, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant material, to prevent leakage and exposure to air or moisture which could potentially lead to decomposition or reactivity issues. |
Shipping | 1,3 - dichloro - 5 - (3,3,3 - trifluoroprop - 1 - en - 2 - yl)benzene is a chemical. It should be shipped in accordance with hazardous chemical regulations, using properly labeled, secure containers to prevent leakage during transit. |
Competitive 1,3-Dichloro-5-(3,3,3-Trifluoroprop-1-En-2-Yl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 1,3-Dichloro-5-(3,3,3-Trifluoroprop-1-En-2-Yl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In the field of medicinal chemistry, such fluorinated organic compounds often have unique physiological activities. Due to the characteristics of fluorine atoms, the physical and chemical properties of compounds such as fat solubility and stability can be changed, which in turn affects their interaction with biological targets. Therefore, it may be used to create new drugs to fight specific diseases, such as the development of some anti-cancer drugs and antiviral agents. With its unique structure and activity, it can precisely act on diseased cells or pathogens to achieve therapeutic purposes.
In the field of materials science, 1,3-difluoro-5- (3,3,3-trifluoropropane-1-alkyne-2-yl) benzene can be used as a key intermediate for the synthesis of special functional materials. Fluorinated materials often have excellent chemical stability, weather resistance, and low surface energy. Based on this compound, high-performance fluoropolymers can be synthesized, which are used to make waterproof, oil-proof and anti-fouling coating materials. They are widely used in construction, textile, automotive and other industries to improve the protective performance and service life of materials.
In addition, in organic synthesis chemistry, its alkynyl and fluoroaryl structures provide a variety of reaction check points for organic synthesis. It can build complex organic molecular structures through various organic reactions, such as coupling reactions and cyclization reactions. It provides important starting materials and intermediates for the synthesis of new organic functional materials and total synthesis of natural products, and promotes the development of organic synthesis chemistry.
Its appearance and morphology are either colorless to pale yellow transparent liquids at room temperature and pressure, or crystalline solids. This is due to the difference in molecular forces, arrangements, melting points, and boiling points of the compounds. If the intermolecular forces are strong, orderly, and have a high melting point, it tends to be solid; conversely, if the force is weak, it is more likely to be liquid.
In terms of boiling point, in view of the fact that the molecule contains fluorine atoms, fluorine is highly electronegative, and there is a strong dipole-dipole interaction between molecules, resulting in a relatively high boiling point. More fluorine atoms increase the polarity of the molecule, and more energy is required to overcome the intermolecular force to boil the liquid. The melting point is affected by the molecular symmetry and the degree of close packing. The structure of the compound may affect the close arrangement of molecules, and the melting point may be within a specific range.
In terms of solubility, according to the principle of similarity and miscibility, hydrophobic groups such as fluoroalkyl groups and benzene rings have poor solubility in water. Because water is a polar solvent, it has weak interaction with hydrophobic groups. However, it has good solubility in non-polar or weakly polar solvents such as dichloromethane, chloroform, and toluene. Due to the interaction between molecules and organic solvents, van der Waals forces can be formed, which is conducive to dissolution.
The density is usually greater than that of water, because the relative atomic weight of fluorine atoms in the molecule is large, increasing the weight per unit volume. And the substitution of fluorine atoms makes the molecular structure compact and further increases the density.
Volatility is relatively low. Due to the strong dipole-dipole interaction and van der Waals force between molecules, it takes more energy for molecules to escape from the liquid surface and enter the gas phase, so volatility is limited.
The physical properties of this compound are of great significance for its application in organic synthesis, materials science and other fields. For example, it can be separated and purified by differential distillation according to boiling point in synthesis, and the solubility can assist in the selection of suitable reaction solvents, providing a basis for research and application in related fields.
Looking at its structure, it contains a dioxy group and a trifluoropropyne group. In the dioxy group, the oxygen atoms are connected by a covalent bond, which has a certain strength. However, the electronegativity of the oxygen atom is quite high, resulting in a certain activity of the dioxy group. Looking at the trifluoropropynyl group, the carbon-carbon triple bond of the alkynyl group contains a high degree of unsaturation, and the electron cloud density is quite high. It is vulnerable to the attack of electrophilic reagents and triggers reactions such as addition. This is the inherent activity of the alkynyl group. In the trifluoromethyl group, the fluorine atom is extremely electronegative, and its electron-absorbing induction effect is significant, which will affect the electron cloud distribution of the alkynyl group and further change its reactivity.
As far as the whole molecule is concerned, different groups affect each other. The dioxy group is connected to the benzene ring containing the trifluoropropynyl group, and the electron effect is transferred within the molecule, or the electron cloud density of the benzene ring changes, which affects the electrophilic substitution reactivity of the benzene ring. And the steric resistance of each
In summary, the chemical properties of 1% 2C3-dioxy-5- (3,3,3-trifluoropropylene-1-alkyne-2-yl) benzene are not completely stable. Under specific conditions, if the appropriate reagent, suitable temperature, pressure, etc., the active groups contained in it may lead to a series of chemical reactions, resulting in changes in the molecular structure. However, under generally mild conditions, if there are no specific initiators, it can still maintain a relatively stable state.
Those who bear the brunt must be well protected. This substance may be toxic and irritating. During operation, protective equipment such as gas masks, protective gloves, goggles, etc. are readily available to ensure that operators are protected from it. And the workplace must be well ventilated to prevent the accumulation of harmful gases and endanger personal safety.
Furthermore, it is crucial to precisely control the reaction conditions. Temperature, pressure, reaction time, and the proportion of reactants are all key factors. If the temperature is too high or the reaction is out of control, if it is too low, the reaction will be slow or even stagnant; improper pressure will also affect the reaction process and product purity. Strict operation according to the established process parameters can ensure the smooth progress of the reaction and obtain the expected product.
The storage and management of the material cannot be ignored. This material may have special storage requirements, such as protection from light, low temperature, drying, etc. The storage container must be well sealed and clearly marked to prevent confusion and misuse. When taking the material, strictly follow the operating procedures and accurately measure it to avoid waste and errors.
Quality inspection is carried out throughout. From raw material input to final product output, all links need to be strictly tested. Whether the purity of raw materials meets the standard or not directly affects the quality of the product; the purity and impurity content of the reaction intermediate product and the final product also need to be carefully analyzed. Only through strict quality control can qualified products be produced.
Maintenance and cleaning of production equipment is also a priority. Regularly check the equipment to ensure its normal operation and avoid affecting production due to equipment failure. After production, clean the equipment in time to prevent material residue from corroding the equipment or affecting the next production.
During the production process, properly dispose of waste. Waste related to this substance may be dangerous and needs to be properly disposed of in accordance with environmental regulations. It must not be discarded at will to avoid polluting the environment.
Looking at its chemical properties, this compound contains many fluorine atoms, which are active in nature, resulting in high chemical stability and difficult to decompose through natural processes. Once released into the environment, it persists for a long time and gradually accumulates in environmental media such as soil and water bodies. In the soil, or change the physical and chemical properties of the soil, hinder the absorption of nutrients and water by plants, inhibit plant growth and development, and even cause plant disease or death, breaking the balance of the ecosystem. In water bodies, it can be dissolved in water, affecting water quality and threatening the survival of aquatic organisms. Many aquatic organisms are sensitive to changes in water quality. This compound exists in water or interferes with its physiological functions, such as destroying the respiratory and reproductive systems, resulting in a decrease in the number of aquatic organisms and a decrease in species diversity.
Furthermore, it volatilizes into the atmosphere, or participates in atmospheric chemical reactions, affecting the atmospheric environment. Although its ozone-destroying potential may not be as good as that of traditional HCFCs, it may affect the concentration of free radicals in the atmosphere and the photochemical reaction process, indirectly affecting climate and air quality. And because of its persistence, it may be transmitted to distant areas with atmospheric circulation, expanding the scope of impact.
In addition, accumulation in organisms is also a key issue. Organisms have enrichment effects. This compound is transmitted through the food chain and the concentration in organisms gradually increases. Organisms at the high end of the food chain, due to the ingestion of low-level organisms containing this compound, the body accumulates more, threatening biological health, or endangering humans through the food chain, causing human health problems, such as affecting endocrine, immune system, etc.

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