Linshang Chemical
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1,3-Dichloro-5-(Trifluoromethyl)Benzene
Linshang Chemical
|
HS Code |
988563 |
| Chemical Formula | C7H3Cl2F3 |
| Molecular Weight | 215.00 |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 170 - 172 °C |
| Density | 1.49 g/cm³ |
| Solubility In Water | Insoluble |
| Flash Point | 65 °C |
| Refractive Index | 1.463 - 1.465 |
As an accredited 1,3-Dichloro-5-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1,3 - Dichloro - 5 - (trifluoromethyl)benzene: Packed in 500 - mL glass bottles, quantity 10 bottles. |
| Storage | 1,3 - dichloro - 5 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent leakage and vapor release. Store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions. |
| Shipping | 1,3 - Dichloro - 5 - (trifluoromethyl)benzene is shipped in tightly sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring secure transport to prevent leakage and environmental or safety risks. |
Competitive 1,3-Dichloro-5-(Trifluoromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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Tel: +8615365006308
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What are the main uses of 1,3-dichloro-5- (trifluoromethyl) benzene?
1% 2C3-diethyl-5- (triethylmethyl) naphthalene is one of the most important compounds. Its main use is in the field of chemical synthesis, and it can be used as an important raw material. Due to its special chemical properties, it can be derived from general chemical reactions. Many compounds with specific uses.
In terms of materials science, with this material-based, polymer materials with excellent properties may be synthesized. For example, it can improve the mechanical properties and chemical corrosion resistance of materials, and is used in materials with demanding properties such as aerospace and automotive manufacturing.
In the process of research, this compound may have biological activity. It can be used to improve the activity of optical devices such as optical diodes (OLEDs) and solar cells. Therefore, 1% 2C3-di- 5- (triethylmethyl) naphthalene has the potential to be effective in treating specific diseases, such as in the research of anti-tumor, anti-virus and other substances.
In addition, it may also play an important role in the field of optical materials. It may be possible to build optical device materials such as optical diodes (OLEDs) and solar cells to improve the optical efficiency of devices. In addition, 1% 2C3-di- (triethyl) naphthalene has the ability to be used in multiple important domains, which is beneficial to promote the development of the phase.
In terms of materials science, with this material-based, polymer materials with excellent properties may be synthesized. For example, it can improve the mechanical properties and chemical corrosion resistance of materials, and is used in materials with demanding properties such as aerospace and automotive manufacturing.
In the process of research, this compound may have biological activity. It can be used to improve the activity of optical devices such as optical diodes (OLEDs) and solar cells. Therefore, 1% 2C3-di- 5- (triethylmethyl) naphthalene has the potential to be effective in treating specific diseases, such as in the research of anti-tumor, anti-virus and other substances.
In addition, it may also play an important role in the field of optical materials. It may be possible to build optical device materials such as optical diodes (OLEDs) and solar cells to improve the optical efficiency of devices. In addition, 1% 2C3-di- (triethyl) naphthalene has the ability to be used in multiple important domains, which is beneficial to promote the development of the phase.
What are the physical properties of 1,3-dichloro-5- (trifluoromethyl) benzene?
1% 2C3-dibromo-5- (triethoxy methyl) benzene-based organic compounds, having the following physical properties:
Appearance properties, often colorless to pale yellow liquid or solid. If it is a liquid, it is clear and transparent and may have a slight color under light; if it is a solid, it may be crystalline or powdery, depending on environmental conditions.
Its melting point will vary due to factors such as purity and intermolecular forces, and it is roughly in a specific temperature range. This property is of great significance in the identification and purity judgment of compounds. Its purity can be preliminarily inferred by melting point measurement. The melting point of pure products is sharp, and the melting point decreases and the melting range widens when impurities are contained.
The boiling point is also an important physical property. Under a specific pressure, the compound will reach the boiling point and change from liquid to gaseous state, which can be separated from other substances with large differences in boiling points for purification or analysis.
In terms of solubility, 1% 2C3 -dibromo-5- (triethoxy methyl) benzene is insoluble in water. Due to the strong hydrogen bonding between water molecules, this compound is an organic structure with a large polar difference from water and weak interaction; but it is soluble in common organic solvents, such as ethanol, ether, chloroform, etc., which provides convenience for its application in organic synthesis reactions and can fully contact and react with other reactants in suitable organic solvents. The density of
is different from that of water. Density measurement can assist in judging its purity or separating substances with different densities such as water in the mixture. Its vapor pressure increases with the increase of temperature. In a closed system, temperature affects the vapor pressure, which requires its storage and use environment. The vapor pressure is high at high temperatures, so care should be taken to prevent leakage from causing safety problems.
Appearance properties, often colorless to pale yellow liquid or solid. If it is a liquid, it is clear and transparent and may have a slight color under light; if it is a solid, it may be crystalline or powdery, depending on environmental conditions.
Its melting point will vary due to factors such as purity and intermolecular forces, and it is roughly in a specific temperature range. This property is of great significance in the identification and purity judgment of compounds. Its purity can be preliminarily inferred by melting point measurement. The melting point of pure products is sharp, and the melting point decreases and the melting range widens when impurities are contained.
The boiling point is also an important physical property. Under a specific pressure, the compound will reach the boiling point and change from liquid to gaseous state, which can be separated from other substances with large differences in boiling points for purification or analysis.
In terms of solubility, 1% 2C3 -dibromo-5- (triethoxy methyl) benzene is insoluble in water. Due to the strong hydrogen bonding between water molecules, this compound is an organic structure with a large polar difference from water and weak interaction; but it is soluble in common organic solvents, such as ethanol, ether, chloroform, etc., which provides convenience for its application in organic synthesis reactions and can fully contact and react with other reactants in suitable organic solvents. The density of
is different from that of water. Density measurement can assist in judging its purity or separating substances with different densities such as water in the mixture. Its vapor pressure increases with the increase of temperature. In a closed system, temperature affects the vapor pressure, which requires its storage and use environment. The vapor pressure is high at high temperatures, so care should be taken to prevent leakage from causing safety problems.
What are the chemical properties of 1,3-dichloro-5- (trifluoromethyl) benzene?
1% 2C3 -difluoro-5- (triethoxy methyl) benzene is an organic compound. Its chemical properties are as follows:
From the structural point of view, the benzene ring is a stable conjugated system, which endows the compound with certain stability. The difluoro substituent, the fluorine atom is extremely electronegative, and has a significant electron-absorbing induction effect. This effect reduces the electron cloud density of the benzene ring and affects its electrophilic substitution reaction activity. Compared with unsubstituted benzene, the electrophilic substitution reaction is more difficult to occur, because the electrophilic reagent is more difficult to attack the benzene ring with low electron cloud density. However, under certain conditions, halogenation, nitrification, sulfonation and other electrophilic substitution reactions can still occur. The position of the substituent is dominated by the localization effect of the fluorine atom. Fluorine is an ortho and para-locator group. Although the benzene ring is passivated, it guides the electrophilic reagents to mainly attack the ortho and para-site.
The substituent of triethoxy methyl contains ethoxy groups, which has a certain electron conjugation effect and spatial steric resistance. The electron-absorbing effect of the fluorine atom can be partially cancelled by the electron conjugation effect of the electron supply, which can adjust the electron cloud density of the benzene ring to a certain extent. Spatial steric resistance affects the intermolecular interaction and the difficulty of the reagent approaching the benzene ring during the chemical reaction. For example, in the nucleophilic substitution reaction, if the
The compound may also participate in some reactions involving ethoxy groups. For example, under acidic conditions, ethoxy groups may hydrolyze to form corresponding alcohols and aldehyde-containing or carbonyl derivatives. Its chemical properties are not only affected by benzene rings and fluorine atoms, but also related to triethoxy methyl groups. Under different reaction conditions, it exhibits a variety of chemical reactivity and products.
From the structural point of view, the benzene ring is a stable conjugated system, which endows the compound with certain stability. The difluoro substituent, the fluorine atom is extremely electronegative, and has a significant electron-absorbing induction effect. This effect reduces the electron cloud density of the benzene ring and affects its electrophilic substitution reaction activity. Compared with unsubstituted benzene, the electrophilic substitution reaction is more difficult to occur, because the electrophilic reagent is more difficult to attack the benzene ring with low electron cloud density. However, under certain conditions, halogenation, nitrification, sulfonation and other electrophilic substitution reactions can still occur. The position of the substituent is dominated by the localization effect of the fluorine atom. Fluorine is an ortho and para-locator group. Although the benzene ring is passivated, it guides the electrophilic reagents to mainly attack the ortho and para-site.
The substituent of triethoxy methyl contains ethoxy groups, which has a certain electron conjugation effect and spatial steric resistance. The electron-absorbing effect of the fluorine atom can be partially cancelled by the electron conjugation effect of the electron supply, which can adjust the electron cloud density of the benzene ring to a certain extent. Spatial steric resistance affects the intermolecular interaction and the difficulty of the reagent approaching the benzene ring during the chemical reaction. For example, in the nucleophilic substitution reaction, if the
The compound may also participate in some reactions involving ethoxy groups. For example, under acidic conditions, ethoxy groups may hydrolyze to form corresponding alcohols and aldehyde-containing or carbonyl derivatives. Its chemical properties are not only affected by benzene rings and fluorine atoms, but also related to triethoxy methyl groups. Under different reaction conditions, it exhibits a variety of chemical reactivity and products.
What are the synthesis methods of 1,3-dichloro-5- (trifluoromethyl) benzene?
There are several methods for the synthesis of 1% 2C3-dideuterium-5- (triethylmethyl) benzene. The first method is to take a suitable benzene derivative and react with it with a specific halogen, which needs to contain triethylmethyl structural units. In a suitable solvent, add an appropriate base to promote the nucleophilic substitution reaction. For bases, or potassium carbonate, sodium carbonate, etc., the solvent can be acetonitrile, N, N-dimethylformamide, etc. The reaction temperature and time also need to be precisely regulated to ensure that the reaction is complete and there are few side reactions.
The second method can first construct an aromatic ring containing triethylmethyl, or by Fourier-gram reaction. Take benzene and triethyl-containing acyl halides or halogenated hydrocarbons, and under the catalysis of Lewis acids such as aluminum trichloride, an acylation or alkylation reaction occurs, and a triethyl group is introduced. Subsequent modification steps such as reduction may be required for the obtained product to obtain the target 1% 2C3 -dideuterium-5- (triethyl) benzene.
Another method can start from deuterium-containing feedstocks, first prepare deuterium-containing benzene derivatives, and then gradually introduce triethyl groups according to the above similar reaction path. When preparing deuterium-containing raw materials, deuterium-substituted reagents such as deuterium-substituted hydrogen halide, deuterium-substituted water, etc. are used to react with corresponding compounds, and deuterium atoms are precisely substituted for hydrogen atoms at the desired position under specific reaction conditions. In this way, after several steps of reaction, the purpose of synthesizing 1% 2C3 -dideuterium-5- (triethylmethyl) benzene can also be achieved. All methods have advantages and disadvantages, and they need to be carefully selected according to the actual situation, such as the availability of raw materials, cost, and difficulty of reaction.
The second method can first construct an aromatic ring containing triethylmethyl, or by Fourier-gram reaction. Take benzene and triethyl-containing acyl halides or halogenated hydrocarbons, and under the catalysis of Lewis acids such as aluminum trichloride, an acylation or alkylation reaction occurs, and a triethyl group is introduced. Subsequent modification steps such as reduction may be required for the obtained product to obtain the target 1% 2C3 -dideuterium-5- (triethyl) benzene.
Another method can start from deuterium-containing feedstocks, first prepare deuterium-containing benzene derivatives, and then gradually introduce triethyl groups according to the above similar reaction path. When preparing deuterium-containing raw materials, deuterium-substituted reagents such as deuterium-substituted hydrogen halide, deuterium-substituted water, etc. are used to react with corresponding compounds, and deuterium atoms are precisely substituted for hydrogen atoms at the desired position under specific reaction conditions. In this way, after several steps of reaction, the purpose of synthesizing 1% 2C3 -dideuterium-5- (triethylmethyl) benzene can also be achieved. All methods have advantages and disadvantages, and they need to be carefully selected according to the actual situation, such as the availability of raw materials, cost, and difficulty of reaction.
What are the precautions for using 1,3-dichloro-5- (trifluoromethyl) benzene?
1% 2C3-dioxo-5- (triethylmethyl) naphthalene is an organic compound. During use, the following things should be paid attention to:
First, this substance has certain toxicity, and the operation must be cautious. Do not let it touch the skin. If it is accidentally contaminated, it should be rinsed with plenty of water immediately and seek medical attention as appropriate. Do not inhale its volatile gas. It should be operated in a well-ventilated place or with the help of ventilation equipment to prevent inhalation poisoning.
Second, it may have an impact on the environment. After use, the residue should not be discarded at will, and it should be properly disposed of in accordance with relevant regulations to avoid pollution to the environment. After experiments or industrial production, waste containing this substance should be classified and collected and handed over to professional institutions for disposal.
Third, storage should also be paid attention to. It should be stored in a cool, dry and ventilated place, away from fire and heat sources. Because of its flammability, in case of open flames, hot topics or combustion explosions, the storage environment must be kept away from dangerous factors such as fire sources. At the same time, it should be stored separately from oxidants and acids, and mixed storage should not be allowed to prevent chemical reactions.
Fourth, the dosage should be precisely controlled when using. According to actual needs, it should be accurately calculated and weighed to achieve the desired effect, avoid waste and reduce latent risk. In the experimental or production process, follow the established standards and operating procedures to ensure that the dosage is correct.
Fifth, those who operate this compound should receive professional training and be familiar with its characteristics, hazards and emergency treatment methods. In this way, in case of emergencies, they can respond calmly and take appropriate measures to ensure personal safety and environmental safety.
First, this substance has certain toxicity, and the operation must be cautious. Do not let it touch the skin. If it is accidentally contaminated, it should be rinsed with plenty of water immediately and seek medical attention as appropriate. Do not inhale its volatile gas. It should be operated in a well-ventilated place or with the help of ventilation equipment to prevent inhalation poisoning.
Second, it may have an impact on the environment. After use, the residue should not be discarded at will, and it should be properly disposed of in accordance with relevant regulations to avoid pollution to the environment. After experiments or industrial production, waste containing this substance should be classified and collected and handed over to professional institutions for disposal.
Third, storage should also be paid attention to. It should be stored in a cool, dry and ventilated place, away from fire and heat sources. Because of its flammability, in case of open flames, hot topics or combustion explosions, the storage environment must be kept away from dangerous factors such as fire sources. At the same time, it should be stored separately from oxidants and acids, and mixed storage should not be allowed to prevent chemical reactions.
Fourth, the dosage should be precisely controlled when using. According to actual needs, it should be accurately calculated and weighed to achieve the desired effect, avoid waste and reduce latent risk. In the experimental or production process, follow the established standards and operating procedures to ensure that the dosage is correct.
Fifth, those who operate this compound should receive professional training and be familiar with its characteristics, hazards and emergency treatment methods. In this way, in case of emergencies, they can respond calmly and take appropriate measures to ensure personal safety and environmental safety.
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