Linshang Chemical
PRODUCTS
1-([4-((2S)Pyrrolidin-2-Yl)Phenyl]Sulfonyl)-4-Chlorobenzene
Linshang Chemical
|
HS Code |
885964 |
| Chemical Name | 1-[(4-[(2S)pyrrolidin-2-yl]phenyl)sulfonyl]-4-chlorobenzene |
| Molecular Formula | C16H18ClNO2S |
| Molecular Weight | 323.84 |
As an accredited 1-([4-((2S)Pyrrolidin-2-Yl)Phenyl]Sulfonyl)-4-Chlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 1-[(4-((2S)pyrrolidin - 2 - yl)phenyl)sulfonyl]-4 - chlorobenzene in sealed chemical - grade packaging. |
| Storage | Store 1-([4-((2S)pyrrolidin - 2 - yl)phenyl]sulfonyl)-4 - chlorobenzene in a cool, dry place away from direct sunlight. Keep it in a tightly sealed container to prevent exposure to moisture and air. Avoid storing near incompatible substances. Ensure the storage area has good ventilation to minimize the risk of fume accumulation. |
| Shipping | The chemical 1 - [(4 - [(2S)pyrrolidin - 2 - yl]phenyl)sulfonyl] - 4 - chlorobenzene will be shipped in sealed, corrosion - resistant containers. Strict safety protocols will be followed, ensuring proper labeling and compliance with hazardous chemical shipping regulations. |
Competitive 1-([4-((2S)Pyrrolidin-2-Yl)Phenyl]Sulfonyl)-4-Chlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
![1-([4-((2S)Pyrrolidin-2-Yl)Phenyl]Sulfonyl)-4-Chlorobenzene](https://alchemist-1317689233.cos.ap-nanjing.myqcloud.com/0f33e070-f267-4eb9-a4e0-654ccc03c1b5/images/product_inner1.jpg)
![1-([4-((2S)Pyrrolidin-2-Yl)Phenyl]Sulfonyl)-4-Chlorobenzene](https://alchemist-1317689233.cos.ap-nanjing.myqcloud.com/0f33e070-f267-4eb9-a4e0-654ccc03c1b5/images/product_inner2.jpg)
Where to Buy 1-([4-((2S)Pyrrolidin-2-Yl)Phenyl]Sulfonyl)-4-Chlorobenzene in China?
As a trusted 1-([4-((2S)Pyrrolidin-2-Yl)Phenyl]Sulfonyl)-4-Chlorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-([4-((2S)Pyrrolidin-2-Yl)Phenyl]Sulfonyl)-4-Chlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 1- ([4- (2s) pyrrolidin-2-yl) phenyl] sulfonyl) -4-chlorobenzene?
1 - ([4- (2S) -pyrrolidine-2-yl) phenyl] sulfonyl) - 4-chlorobenzene, which is an organic compound. The analysis of its chemical structure needs to be viewed one by one from each part.
"1 -" and "4 -" show the position of the substituent on the benzene ring. The benzene ring is a six-membered carbon ring with unique stability and reactivity.
"4-chlorobenzene" means that the fourth position of the benzene ring is replaced by a chlorine atom. Chlorine atom, with electronegativity, has an impact on the electron cloud distribution and chemical properties of the benzene ring, which can reduce the electron cloud density of the benzene ring and change the electrophilic substitution activity of the benzene ring.
" ([4- ((2S) -pyrrolidine-2-yl) phenyl] sulfonyl) ", this part of the structure is more complex. "Phenyl" is the group after the benzene ring has removed a hydrogen atom and is connected to the main benzene ring. "4- ((2S) -pyrrolidine-2-yl) ", indicating that there is (2S) -pyrrolidine-2-yl connected at the 4th position of the phenyl group. Pyrrolidine, a nitrogen-containing five-membered heterocyclic ring, (2S) indicates that the configuration of its second carbon atom is S-type. This heterocyclic structure endows the compound with a unique spatial configuration and electronic effects.
"Sulfonyl", -SO 2O -, connects phenyl to the main benzene ring. Sulfonyl groups have strong electron-absorbing properties, which can significantly affect the electron cloud distribution and polarity of molecules, and then affect the physical and chemical properties of compounds, such as solubility, acidity and alkalinity, and reactivity.
In summary, the chemical structure of 1- ([4- ((2S) -pyrrolidine-2-yl) phenyl] sulfonyl) -4-chlorobenzene is composed of phenyl ring, chlorine atom, phenyl group containing specific pyrrolidine group and sulfonyl group. The interaction of each part endows the compound with unique chemical properties and potential application value.
"1 -" and "4 -" show the position of the substituent on the benzene ring. The benzene ring is a six-membered carbon ring with unique stability and reactivity.
"4-chlorobenzene" means that the fourth position of the benzene ring is replaced by a chlorine atom. Chlorine atom, with electronegativity, has an impact on the electron cloud distribution and chemical properties of the benzene ring, which can reduce the electron cloud density of the benzene ring and change the electrophilic substitution activity of the benzene ring.
" ([4- ((2S) -pyrrolidine-2-yl) phenyl] sulfonyl) ", this part of the structure is more complex. "Phenyl" is the group after the benzene ring has removed a hydrogen atom and is connected to the main benzene ring. "4- ((2S) -pyrrolidine-2-yl) ", indicating that there is (2S) -pyrrolidine-2-yl connected at the 4th position of the phenyl group. Pyrrolidine, a nitrogen-containing five-membered heterocyclic ring, (2S) indicates that the configuration of its second carbon atom is S-type. This heterocyclic structure endows the compound with a unique spatial configuration and electronic effects.
"Sulfonyl", -SO 2O -, connects phenyl to the main benzene ring. Sulfonyl groups have strong electron-absorbing properties, which can significantly affect the electron cloud distribution and polarity of molecules, and then affect the physical and chemical properties of compounds, such as solubility, acidity and alkalinity, and reactivity.
In summary, the chemical structure of 1- ([4- ((2S) -pyrrolidine-2-yl) phenyl] sulfonyl) -4-chlorobenzene is composed of phenyl ring, chlorine atom, phenyl group containing specific pyrrolidine group and sulfonyl group. The interaction of each part endows the compound with unique chemical properties and potential application value.
What are the physical properties of 1- ([4- (2s) pyrrolidin-2-yl) phenyl] sulfonyl) -4-chlorobenzene?
1-%28+%5B4-%28%282s%29pyrrolidin-2-yl%29phenyl%5Dsulfonyl%29-4-chlorobenzene is an organic compound. It has specific physical properties, let me talk about them one by one.
When it comes to appearance, this compound is usually in a solid state, and the specific color state may vary depending on the purity and crystal form. It often appears white to off-white powder, and its texture is fine and uniform.
In terms of solubility, this compound exhibits different solubility characteristics in organic solvents. Common polar organic solvents, such as dichloromethane and chloroform, have a certain solubility to it, which can disperse the compound to form a homogeneous solution; in water, due to the large proportion of hydrophobic groups in its structure, it has poor solubility and is insoluble or slightly soluble in water.
Its melting point is also one of the important physical properties. The melting point is determined by experiments in a certain temperature range, which is of great significance for the identification and purification of the compound. When heated to this temperature range, the compound gradually changes from solid state to liquid state, achieving phase transition, and this melting point range is relatively fixed, which is a key indicator for its characteristic characterization.
Then talking about the boiling point, under specific pressure conditions, the compound will reach the boiling point and boil and vaporize. The value of the boiling point is closely related to the intermolecular force of the compound. The intermolecular force determines the boiling point of the compound, and the boiling point data is crucial for its separation, purification and reaction conditions control.
In addition, density, as one of the physical properties, cannot be ignored. Although the density values may vary slightly due to measurement conditions, under certain conditions, it has a relatively stable value, which is of great significance for the distribution and behavior of compounds in different media.
The physical properties of this compound have a profound impact on its application in organic synthesis, drug development and other fields. According to these properties, researchers can reasonably design the reaction and separation process to achieve the expected experimental purpose.
When it comes to appearance, this compound is usually in a solid state, and the specific color state may vary depending on the purity and crystal form. It often appears white to off-white powder, and its texture is fine and uniform.
In terms of solubility, this compound exhibits different solubility characteristics in organic solvents. Common polar organic solvents, such as dichloromethane and chloroform, have a certain solubility to it, which can disperse the compound to form a homogeneous solution; in water, due to the large proportion of hydrophobic groups in its structure, it has poor solubility and is insoluble or slightly soluble in water.
Its melting point is also one of the important physical properties. The melting point is determined by experiments in a certain temperature range, which is of great significance for the identification and purification of the compound. When heated to this temperature range, the compound gradually changes from solid state to liquid state, achieving phase transition, and this melting point range is relatively fixed, which is a key indicator for its characteristic characterization.
Then talking about the boiling point, under specific pressure conditions, the compound will reach the boiling point and boil and vaporize. The value of the boiling point is closely related to the intermolecular force of the compound. The intermolecular force determines the boiling point of the compound, and the boiling point data is crucial for its separation, purification and reaction conditions control.
In addition, density, as one of the physical properties, cannot be ignored. Although the density values may vary slightly due to measurement conditions, under certain conditions, it has a relatively stable value, which is of great significance for the distribution and behavior of compounds in different media.
The physical properties of this compound have a profound impact on its application in organic synthesis, drug development and other fields. According to these properties, researchers can reasonably design the reaction and separation process to achieve the expected experimental purpose.
What are the main uses of 1- ([4- (2s) pyrrolidin-2-yl) phenyl] sulfonyl) -4-chlorobenzene?
1- ([4- (2S) -pyrrolidine-2-yl) phenyl] sulfonyl) -4-chlorobenzene has a rather specific use. However, in the ancient books of our country, it is difficult to find an exact match for it. Today, it can only be deduced according to the current chemical knowledge and application field.
In the field of medicinal chemistry, it may be a key intermediate for the development of new drugs. The development of Guanfu drugs often requires exquisite organic molecular structures to fit specific targets in organisms and exert therapeutic effects. The unique structure of this compound, containing pyrrolidine groups, sulfonyl groups, chlorobenzene and other parts, may endow it with specific biological activities. Pyrrolidine structures are common in many drugs, with properties such as modulating molecular lipophilicity and interacting with biomacromolecules; sulfonyl groups may affect the electron cloud distribution and water solubility of compounds; chlorobenzene moiety also contributes to its physicochemical properties. In combination, it may be chemically modified to bind to proteins, enzymes and other targets in the body in a specific way for the treatment of diseases such as inflammation and tumors.
In the field of materials science, or can participate in the preparation of special materials. In the field of materials today, there is a growing demand for substances with special properties. The structure of this compound may give the material unique electrical, optical or mechanical properties. For example, in organic semiconductor materials, its structure may affect the charge transfer efficiency between molecules, which in turn affects the electrical conductivity of the material; in optical materials, or because of its specific electronic transition characteristics, it affects the optical behavior of the material such as light absorption and emission, providing the possibility for the development of new optoelectronic devices.
In the fine chemical industry, it can be used as a raw material for special chemicals. Fine chemicals focus on high added value and specific functions of products. The unique structure of this compound can be converted into fine chemicals with special functions through a series of chemical reactions, such as special surfactants, high-performance catalyst ligands, etc., to help upgrade fine chemical products.
In the field of medicinal chemistry, it may be a key intermediate for the development of new drugs. The development of Guanfu drugs often requires exquisite organic molecular structures to fit specific targets in organisms and exert therapeutic effects. The unique structure of this compound, containing pyrrolidine groups, sulfonyl groups, chlorobenzene and other parts, may endow it with specific biological activities. Pyrrolidine structures are common in many drugs, with properties such as modulating molecular lipophilicity and interacting with biomacromolecules; sulfonyl groups may affect the electron cloud distribution and water solubility of compounds; chlorobenzene moiety also contributes to its physicochemical properties. In combination, it may be chemically modified to bind to proteins, enzymes and other targets in the body in a specific way for the treatment of diseases such as inflammation and tumors.
In the field of materials science, or can participate in the preparation of special materials. In the field of materials today, there is a growing demand for substances with special properties. The structure of this compound may give the material unique electrical, optical or mechanical properties. For example, in organic semiconductor materials, its structure may affect the charge transfer efficiency between molecules, which in turn affects the electrical conductivity of the material; in optical materials, or because of its specific electronic transition characteristics, it affects the optical behavior of the material such as light absorption and emission, providing the possibility for the development of new optoelectronic devices.
In the fine chemical industry, it can be used as a raw material for special chemicals. Fine chemicals focus on high added value and specific functions of products. The unique structure of this compound can be converted into fine chemicals with special functions through a series of chemical reactions, such as special surfactants, high-performance catalyst ligands, etc., to help upgrade fine chemical products.
What are the synthesis methods of 1- ([4- (2s) pyrrolidin-2-yl) phenyl] sulfonyl) -4-chlorobenzene?
To prepare 1- ([4- (2S) -pyrrolid- 2-yl) phenyl] sulfonyl) -4-chlorobenzene, there are many methods, and each has its advantages and disadvantages, which must be selected according to the actual situation.
First, 4-chlorobenzenesulfonyl chloride and pyrrolid- containing phenyl derivatives are used as raw materials, which can be obtained by condensation reaction. Among them, 4-chlorobenzenesulfonyl chloride has good activity, but it requires strict reaction conditions, and the temperature and humidity are slightly poor, which will affect the yield. The preparation of phenyl derivatives containing pyrrolidinyl is also not easy, requiring multi-step reactions, and the purification of intermediate products is complicated. If there is a slight carelessness, impurities will be mixed in, which will affect the purity of the final product.
Second, halogenated benzene and compounds containing pyrrolidinyl and sulfonyl groups are prepared by metal catalytic coupling reaction. Metal catalysts such as palladium and nickel can efficiently promote the reaction, but they are expensive, and the separation and recovery of catalysts after the reaction are difficult, which is easy to cause cost increase and environmental pollution. At the same time, the coupling reaction conditions are complex, the requirements for reaction equipment are high, and a strict anhydrous and oxygen-free environment is required, which is difficult to operate.
Third, the pyrrolidyl-containing benzenesulfonic acid derivative is synthesized first, and then chlorine atoms are introduced through chlorination reaction. Although there are many steps in this pathway, the reaction of each step is highly controllable and the purity of the product is easy to ensure. During chlorination reaction, the selection of chlorine source and the control of reaction conditions are crucial, otherwise it is easy to form polychlorinated by-products and affect the quality of the target product.
When synthesizing 1- ([4- ((2S) -pyrrolidine-2-yl) phenyl] sulfonyl) -4 -chlorobenzene, it is necessary to comprehensively consider the availability of raw materials, cost, equipment conditions and the requirements for product purity and yield, and carefully choose the synthesis method to obtain it efficiently.
First, 4-chlorobenzenesulfonyl chloride and pyrrolid- containing phenyl derivatives are used as raw materials, which can be obtained by condensation reaction. Among them, 4-chlorobenzenesulfonyl chloride has good activity, but it requires strict reaction conditions, and the temperature and humidity are slightly poor, which will affect the yield. The preparation of phenyl derivatives containing pyrrolidinyl is also not easy, requiring multi-step reactions, and the purification of intermediate products is complicated. If there is a slight carelessness, impurities will be mixed in, which will affect the purity of the final product.
Second, halogenated benzene and compounds containing pyrrolidinyl and sulfonyl groups are prepared by metal catalytic coupling reaction. Metal catalysts such as palladium and nickel can efficiently promote the reaction, but they are expensive, and the separation and recovery of catalysts after the reaction are difficult, which is easy to cause cost increase and environmental pollution. At the same time, the coupling reaction conditions are complex, the requirements for reaction equipment are high, and a strict anhydrous and oxygen-free environment is required, which is difficult to operate.
Third, the pyrrolidyl-containing benzenesulfonic acid derivative is synthesized first, and then chlorine atoms are introduced through chlorination reaction. Although there are many steps in this pathway, the reaction of each step is highly controllable and the purity of the product is easy to ensure. During chlorination reaction, the selection of chlorine source and the control of reaction conditions are crucial, otherwise it is easy to form polychlorinated by-products and affect the quality of the target product.
When synthesizing 1- ([4- ((2S) -pyrrolidine-2-yl) phenyl] sulfonyl) -4 -chlorobenzene, it is necessary to comprehensively consider the availability of raw materials, cost, equipment conditions and the requirements for product purity and yield, and carefully choose the synthesis method to obtain it efficiently.
1- ([4- ((2s) pyrrolidin-2-yl) phenyl] sulfonyl) -4-chlorobenzene What are the precautions during use?
1-% (+ [4- (2s) pyrrolidin-2-yl) phenyl] sulfonyl) -4-chlorobenzene is a chemical compound. When using it, you need to pay attention to the general situation.
First, it is very important to be safe. This compound may have certain toxicity and irritation, and it must be followed by safe operation. When using it, you need to prevent it from being used, such as clothing, gloves, eyes, etc. If you accidentally connect it, wash it with plenty of water immediately, and treat it according to your symptoms. The operation should be done in a good way, preferably in a good way, to prevent harmful steaming and inhalation.
Furthermore, the chemical characteristics should not be ignored. It is necessary to be familiar with its chemical properties, such as solubility, qualitative, etc. According to its characteristics, choose the right amount of dissolution. If the solubility is not good, other dissolution systems may need to be explored to ensure the reverse effect. And pay attention to its quality. In some cases, it may be easy to decompose, affect, and affect the use effect. Therefore, it needs to be properly stored and stored in the environment according to the requirements of the regulations.
The operation also needs to be careful. The dosage must be precise and the amount must be used to avoid the amount or insufficient, and the impact will be reversed. To reduce the reverse effect, it is necessary to control the reverse effect, such as the degree of resistance, force, reaction, etc. Under different conditions, the reverse effect, rate or large phase will be different.
In addition, the treatment of the reverse effect should not be improved. After use, the leftovers and reverse effects must not be destroyed according to the relevant conditions. Collect and properly handle, so as not to pollute the environment.
Therefore, the use of 1-% (+ [4- (2s) pyrrolidin-2-yl) phenyl] sulfonyl) -4-chlorobenzene requires careful consideration in various aspects such as safety, characteristics, operation, and physical management in order to ensure the safety of the use process and achieve the purpose of the period.
First, it is very important to be safe. This compound may have certain toxicity and irritation, and it must be followed by safe operation. When using it, you need to prevent it from being used, such as clothing, gloves, eyes, etc. If you accidentally connect it, wash it with plenty of water immediately, and treat it according to your symptoms. The operation should be done in a good way, preferably in a good way, to prevent harmful steaming and inhalation.
Furthermore, the chemical characteristics should not be ignored. It is necessary to be familiar with its chemical properties, such as solubility, qualitative, etc. According to its characteristics, choose the right amount of dissolution. If the solubility is not good, other dissolution systems may need to be explored to ensure the reverse effect. And pay attention to its quality. In some cases, it may be easy to decompose, affect, and affect the use effect. Therefore, it needs to be properly stored and stored in the environment according to the requirements of the regulations.
The operation also needs to be careful. The dosage must be precise and the amount must be used to avoid the amount or insufficient, and the impact will be reversed. To reduce the reverse effect, it is necessary to control the reverse effect, such as the degree of resistance, force, reaction, etc. Under different conditions, the reverse effect, rate or large phase will be different.
In addition, the treatment of the reverse effect should not be improved. After use, the leftovers and reverse effects must not be destroyed according to the relevant conditions. Collect and properly handle, so as not to pollute the environment.
Therefore, the use of 1-% (+ [4- (2s) pyrrolidin-2-yl) phenyl] sulfonyl) -4-chlorobenzene requires careful consideration in various aspects such as safety, characteristics, operation, and physical management in order to ensure the safety of the use process and achieve the purpose of the period.
Scan to WhatsApp
