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1-((4-(Chloromethyl)Phenoxy)Methyl)-3-Fluorobenzene
Linshang Chemical
|
HS Code |
337236 |
| Chemical Formula | C15H12ClFO |
| Molecular Weight | 264.71 |
| Appearance | Solid (usually) |
| Solubility In Water | Low solubility, being an organic compound |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Stability | Stable under normal conditions, may react with strong oxidizing agents |
As an accredited 1-((4-(Chloromethyl)Phenoxy)Methyl)-3-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 1-((4-(chloromethyl)phenoxy)methyl)-3-fluorobenzene in sealed chemical - grade containers. |
| Storage | 1-( (4-(Chloromethyl)phenoxy)methyl)-3 -fluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container to prevent leakage and exposure to air and moisture, which could potentially cause decomposition or unwanted reactions. |
| Shipping | 1-( (4-(Chloromethyl)phenoxy)methyl)-3-fluorobenzene is shipped in specialized, tightly - sealed containers compliant with chemical transport regulations. Shipment ensures protection from external factors and proper handling to prevent any leakage or hazard. |
Competitive 1-((4-(Chloromethyl)Phenoxy)Methyl)-3-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
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What are the main uses of 1- (4- (chloromethyl) phenoxy) methyl) -3-fluorobenzene?
1 - ((4- (methoxy) phenoxy) methyl) -3 -chlorobenzene, which is an important raw material for organic synthesis, has critical uses in many fields such as medicine, pesticides and materials science.
In the field of medicine, it can be used as an intermediate for the synthesis of specific drugs. For example, in the development of some targeted drugs with special efficacy, 1- ((4- (methoxy) phenoxy) methyl) -3 -chlorobenzene can impart specific structure and activity to drug molecules, which helps to accurately act on disease targets, improve drug treatment effects and reduce side effects. Its unique chemical structure can participate in many key reactions in the drug synthesis process, such as nucleophilic substitution, coupling reactions, etc., laying the foundation for the construction of complex drug molecular skeletons.
In the field of pesticides, this compound can be chemically modified and modified to produce pesticide products with high-efficiency insecticidal, bactericidal or herbicidal activities. Due to its structural characteristics, it can produce significant biological activity against specific pests, bacteria or weeds, effectively inhibiting their growth, reproduction or metabolic processes, so as to achieve the purpose of crop protection and yield increase. And its degradation characteristics in the environment are relatively good, which helps to reduce the long-term negative impact on the ecological environment.
In the field of materials science, 1- ((4- (methoxy) phenoxy) methyl) -3 -chlorobenzene can be used to synthesize functional polymer materials. By polymerizing with other monomers, polymer materials can impart special optical, electrical or thermal properties. For example, the synthesized new polymer materials may have excellent electrical conductivity, photochromic or thermal stability, and are widely used in electronic devices, optical sensors and high-performance composites to promote progress and innovation in materials science and technology.
In the field of medicine, it can be used as an intermediate for the synthesis of specific drugs. For example, in the development of some targeted drugs with special efficacy, 1- ((4- (methoxy) phenoxy) methyl) -3 -chlorobenzene can impart specific structure and activity to drug molecules, which helps to accurately act on disease targets, improve drug treatment effects and reduce side effects. Its unique chemical structure can participate in many key reactions in the drug synthesis process, such as nucleophilic substitution, coupling reactions, etc., laying the foundation for the construction of complex drug molecular skeletons.
In the field of pesticides, this compound can be chemically modified and modified to produce pesticide products with high-efficiency insecticidal, bactericidal or herbicidal activities. Due to its structural characteristics, it can produce significant biological activity against specific pests, bacteria or weeds, effectively inhibiting their growth, reproduction or metabolic processes, so as to achieve the purpose of crop protection and yield increase. And its degradation characteristics in the environment are relatively good, which helps to reduce the long-term negative impact on the ecological environment.
In the field of materials science, 1- ((4- (methoxy) phenoxy) methyl) -3 -chlorobenzene can be used to synthesize functional polymer materials. By polymerizing with other monomers, polymer materials can impart special optical, electrical or thermal properties. For example, the synthesized new polymer materials may have excellent electrical conductivity, photochromic or thermal stability, and are widely used in electronic devices, optical sensors and high-performance composites to promote progress and innovation in materials science and technology.
What are the physical properties of 1- (4- (chloromethyl) phenoxy) methyl) -3-fluorobenzene
1 - ((4- (methoxy) phenoxy) methyl) - 3 - chlorobenzene, this substance is an organic compound. Its physical properties are rich and diverse.
Looking at its appearance, it may be a colorless to light yellow liquid under normal conditions, or a white to off-white solid. The specific shape varies depending on the environmental conditions. In terms of solubility, it exhibits good solubility in organic solvents such as ethanol, ether, and dichloromethane. Due to the principle of similar miscibility, the compound is similar in structure to organic solvents, so it can be miscible with each other. However, in water, its solubility is poor because its molecular structure lacks groups that strongly interact with water molecules.
Talking about the melting point, if it is a solid state, the melting point can be measured or in a specific temperature range. This temperature range can be used as an important physical parameter to identify the compound. The melting point is affected by the intermolecular forces, and the size of the intermolecular forces of the compound determines its melting point.
The boiling point is also a key physical property. If it is a liquid, its boiling point is also in a specific temperature range. The boiling point reflects the energy required for a compound to change from a liquid state to a gaseous state, which is related to the intermolecular forces and the relative molecular mass.
In terms of density, the density value can be obtained by measuring its density. Density is one of the characteristics of the substance. It is of great significance in the fields of chemical production and quality testing. The purity of the compound can be preliminarily judged by density.
In addition, refractive index is also one of its physical properties. Refractive index reflects the degree of refraction when light passes through the substance, and is an indispensable physical constant for identifying the purity and structure of compounds.
The above physical properties play an important role in many fields such as organic synthesis, drug development, and materials science. In organic synthesis, the reaction solvent can be reasonably selected according to its solubility to promote the smooth progress of the reaction; in drug development, properties such as melting point and boiling point are related to drug stability and preparation process; in the field of materials science, properties such as density and refractive index provide key basis for material performance optimization.
Looking at its appearance, it may be a colorless to light yellow liquid under normal conditions, or a white to off-white solid. The specific shape varies depending on the environmental conditions. In terms of solubility, it exhibits good solubility in organic solvents such as ethanol, ether, and dichloromethane. Due to the principle of similar miscibility, the compound is similar in structure to organic solvents, so it can be miscible with each other. However, in water, its solubility is poor because its molecular structure lacks groups that strongly interact with water molecules.
Talking about the melting point, if it is a solid state, the melting point can be measured or in a specific temperature range. This temperature range can be used as an important physical parameter to identify the compound. The melting point is affected by the intermolecular forces, and the size of the intermolecular forces of the compound determines its melting point.
The boiling point is also a key physical property. If it is a liquid, its boiling point is also in a specific temperature range. The boiling point reflects the energy required for a compound to change from a liquid state to a gaseous state, which is related to the intermolecular forces and the relative molecular mass.
In terms of density, the density value can be obtained by measuring its density. Density is one of the characteristics of the substance. It is of great significance in the fields of chemical production and quality testing. The purity of the compound can be preliminarily judged by density.
In addition, refractive index is also one of its physical properties. Refractive index reflects the degree of refraction when light passes through the substance, and is an indispensable physical constant for identifying the purity and structure of compounds.
The above physical properties play an important role in many fields such as organic synthesis, drug development, and materials science. In organic synthesis, the reaction solvent can be reasonably selected according to its solubility to promote the smooth progress of the reaction; in drug development, properties such as melting point and boiling point are related to drug stability and preparation process; in the field of materials science, properties such as density and refractive index provide key basis for material performance optimization.
Is 1- ((4- (chloromethyl) phenoxy) methyl) -3-fluorobenzene chemically stable?
This is a question about the chemical stability of (1- ((4- (methoxy) phenoxy) methyl) -3 -chlorobenzene). I will try to answer it in the classical style of "Tiangong Kaiwu".
The stability of the chemical properties of Fu (1- ((4- (methoxy) phenoxy) methyl) -3 -chlorobenzene) depends on many factors. From the perspective of its molecular structure, the existence of the benzene ring gives it a certain stability. The benzene ring has a conjugated large π bond, the electron cloud is uniformly distributed, and the structure is relatively stable. The methoxy group is attached to the benzene ring, and the methoxy group is the donator group, which can increase the electron cloud density of the benzene ring through electron delocalization. This electronic effect can affect the reactivity of the molecule and enhance the stability of the molecule to a certain extent. Due to the action of the donator, it can reduce the tendency of the benzene ring to be attacked by electrophilic reagents.
Although the chlorine atom is attached to the benzene ring, although it is an electron-withdrawing group, the p-orbital of the chlorine atom and the π-orbital of the benzene ring can form a p-π conjugate, which also contributes to the molecular stability. However, the electron-withdrawing induction effect of the chlorine atom may reduce the electron cloud density of the benzene ring under certain
Looking at its overall structure, (4- (methoxy) phenoxy) methyl is attached to the benzene ring. The existence of ether bonds in this structure is relatively stable under normal conditions, but under extreme conditions such as strong acid, strong base or high temperature, ether bonds may break, which in turn affects the stability of the entire molecule.
In summary, (1- (4- (methoxy) phenoxy) methyl) -3 -chlorobenzene) has certain stability under conventional conditions due to the conjugation structure of the benzene ring, the action of the methoxy group and the conjugation effect of the chlorine atom. However, when encountering special conditions such as strong acid, strong alkali, and high temperature, some chemical bonds in its molecular structure may be affected, and the stability will also change accordingly.
The stability of the chemical properties of Fu (1- ((4- (methoxy) phenoxy) methyl) -3 -chlorobenzene) depends on many factors. From the perspective of its molecular structure, the existence of the benzene ring gives it a certain stability. The benzene ring has a conjugated large π bond, the electron cloud is uniformly distributed, and the structure is relatively stable. The methoxy group is attached to the benzene ring, and the methoxy group is the donator group, which can increase the electron cloud density of the benzene ring through electron delocalization. This electronic effect can affect the reactivity of the molecule and enhance the stability of the molecule to a certain extent. Due to the action of the donator, it can reduce the tendency of the benzene ring to be attacked by electrophilic reagents.
Although the chlorine atom is attached to the benzene ring, although it is an electron-withdrawing group, the p-orbital of the chlorine atom and the π-orbital of the benzene ring can form a p-π conjugate, which also contributes to the molecular stability. However, the electron-withdrawing induction effect of the chlorine atom may reduce the electron cloud density of the benzene ring under certain
Looking at its overall structure, (4- (methoxy) phenoxy) methyl is attached to the benzene ring. The existence of ether bonds in this structure is relatively stable under normal conditions, but under extreme conditions such as strong acid, strong base or high temperature, ether bonds may break, which in turn affects the stability of the entire molecule.
In summary, (1- (4- (methoxy) phenoxy) methyl) -3 -chlorobenzene) has certain stability under conventional conditions due to the conjugation structure of the benzene ring, the action of the methoxy group and the conjugation effect of the chlorine atom. However, when encountering special conditions such as strong acid, strong alkali, and high temperature, some chemical bonds in its molecular structure may be affected, and the stability will also change accordingly.
What are the synthesis methods of 1- (4- (chloromethyl) phenoxy) methyl) -3-fluorobenzene
To prepare 1 - (4 - (methoxy) phenoxy) methyl) - 3 - chlorobenzene, there are many methods for its synthesis, which are described in ancient methods.
First, it can be prepared from the starting material through a multi-step reaction. First, take the appropriate aromatic compound, make it and the reagent containing methoxy and phenoxy groups, under suitable reaction conditions, such as in a specific catalyst, temperature and solvent environment, Substitution reaction occurs, and introduce (4 - (methoxy) phenoxy) methyl group into the aromatic ring. This reaction requires fine regulation of various reaction parameters to ensure that the reaction proceeds in the desired direction, and the purity and yield of the product are good.
Then, the compound that has been introduced into a specific group is chlorinated. Select a suitable chlorination reagent, such as a commonly used chlorine-containing halogenating agent, and chlorinate a specific position of the benzene ring under suitable reaction conditions to obtain the target product 1 - ((4- (methoxy) phenoxy) methyl) - 3 - chlorobenzene. This chlorination step also requires careful control of the reaction conditions to avoid excessive chlorination or the formation of other by-products, which affect the quality and yield of the product.
Second, there are other synthesis paths. The chlorine-containing benzene ring structure can be constructed first, and then the (4- (methoxy) phenoxy) methyl group can be gradually introduced. Starting with chlorine-containing aromatic raw materials, through a series of reactions, such as reacting with appropriate nucleophilic reagents, a specific intermediate product is formed. After that, the intermediate product interacts with reagents containing methoxy and phenoxy groups, and reacts such as nucleophilic substitution to finally obtain the target compound. This path also requires precise control of the conditions of each step of the reaction, from the ratio of reaction substrates, reaction temperature, reaction time to the catalyst used, etc., all affect the success or failure of the synthesis and the quality of the product.
Synthesis of this compound requires a deep understanding of the reaction mechanism, and in actual operation, strict follow of experimental specifications, and fine control of each reaction link, in order to effectively improve the yield and purity of the product and achieve the purpose of synthesis.
First, it can be prepared from the starting material through a multi-step reaction. First, take the appropriate aromatic compound, make it and the reagent containing methoxy and phenoxy groups, under suitable reaction conditions, such as in a specific catalyst, temperature and solvent environment, Substitution reaction occurs, and introduce (4 - (methoxy) phenoxy) methyl group into the aromatic ring. This reaction requires fine regulation of various reaction parameters to ensure that the reaction proceeds in the desired direction, and the purity and yield of the product are good.
Then, the compound that has been introduced into a specific group is chlorinated. Select a suitable chlorination reagent, such as a commonly used chlorine-containing halogenating agent, and chlorinate a specific position of the benzene ring under suitable reaction conditions to obtain the target product 1 - ((4- (methoxy) phenoxy) methyl) - 3 - chlorobenzene. This chlorination step also requires careful control of the reaction conditions to avoid excessive chlorination or the formation of other by-products, which affect the quality and yield of the product.
Second, there are other synthesis paths. The chlorine-containing benzene ring structure can be constructed first, and then the (4- (methoxy) phenoxy) methyl group can be gradually introduced. Starting with chlorine-containing aromatic raw materials, through a series of reactions, such as reacting with appropriate nucleophilic reagents, a specific intermediate product is formed. After that, the intermediate product interacts with reagents containing methoxy and phenoxy groups, and reacts such as nucleophilic substitution to finally obtain the target compound. This path also requires precise control of the conditions of each step of the reaction, from the ratio of reaction substrates, reaction temperature, reaction time to the catalyst used, etc., all affect the success or failure of the synthesis and the quality of the product.
Synthesis of this compound requires a deep understanding of the reaction mechanism, and in actual operation, strict follow of experimental specifications, and fine control of each reaction link, in order to effectively improve the yield and purity of the product and achieve the purpose of synthesis.
What are the precautions for 1- ((4- (chloromethyl) phenoxy) methyl) -3-fluorobenzene during storage and transportation?
When storing and transporting 1 - {[4 - (methoxy) phenoxy] methyl} - 3 - chlorobenzene, there are many key things to be aware of.
This substance has special properties and must be stored in a cool, dry and well-ventilated place. Because it may be sensitive to temperature and humidity, high temperature and humid environments may cause chemical reactions, damage quality, or even cause danger. Avoid direct sunlight, which may cause it to decompose or cause other adverse changes.
Store away from fire, heat, and strong oxidants. This substance may be flammable. In case of open flames and hot topics, it is easy to cause combustion and explosion; in contact with strong oxidants, or trigger violent reactions, threatening safety. The storage area shall be equipped with corresponding fire-fighting equipment and leakage emergency treatment equipment for emergencies.
During transportation, the packaging must be solid and tight to ensure that it can withstand normal transportation vibration, collision and temperature changes to prevent leakage. Transportation vehicles shall comply with relevant hazardous chemical transportation standards and be equipped with grounding devices to eliminate static electricity and avoid fires or explosions caused by static electricity.
Transportation personnel must undergo professional training and be familiar with the characteristics of the substance and emergency treatment methods. During transportation, pay close attention to the status of the goods. If there is any abnormality, deal with it properly in time. At the same time, strictly follow the specified transportation routes, avoid sensitive areas such as densely populated areas and water sources, and reduce latent risks. In short, whether it is storage or transportation, it must be strictly operated in accordance with specifications to ensure the safety of personnel and the environment.
This substance has special properties and must be stored in a cool, dry and well-ventilated place. Because it may be sensitive to temperature and humidity, high temperature and humid environments may cause chemical reactions, damage quality, or even cause danger. Avoid direct sunlight, which may cause it to decompose or cause other adverse changes.
Store away from fire, heat, and strong oxidants. This substance may be flammable. In case of open flames and hot topics, it is easy to cause combustion and explosion; in contact with strong oxidants, or trigger violent reactions, threatening safety. The storage area shall be equipped with corresponding fire-fighting equipment and leakage emergency treatment equipment for emergencies.
During transportation, the packaging must be solid and tight to ensure that it can withstand normal transportation vibration, collision and temperature changes to prevent leakage. Transportation vehicles shall comply with relevant hazardous chemical transportation standards and be equipped with grounding devices to eliminate static electricity and avoid fires or explosions caused by static electricity.
Transportation personnel must undergo professional training and be familiar with the characteristics of the substance and emergency treatment methods. During transportation, pay close attention to the status of the goods. If there is any abnormality, deal with it properly in time. At the same time, strictly follow the specified transportation routes, avoid sensitive areas such as densely populated areas and water sources, and reduce latent risks. In short, whether it is storage or transportation, it must be strictly operated in accordance with specifications to ensure the safety of personnel and the environment.
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