Linshang Chemical
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1,5-Dichloro-2-Nitro-4-(Trifluoromethyl)Benzene
Linshang Chemical
|
HS Code |
360027 |
| Chemical Formula | C7H2Cl2F3NO2 |
| Molar Mass | 260.00 g/mol |
| Appearance | Solid (usually) |
| Color | May be colorless to pale - colored |
| Odor | Characteristic, likely pungent |
| Solubility In Water | Low solubility in water |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Boiling Point | Data may vary, but generally high due to molecular weight and structure |
| Melting Point | Specific value would need experimental determination |
| Density | Value depends on conditions, density is greater than 1 g/cm³ typically for such aromatic compounds |
| Stability | Stable under normal conditions, but may react with strong reducing or oxidizing agents |
| Hazardous Nature | Toxic, may cause harm to skin, eyes, and respiratory system; may be an environmental hazard |
As an accredited 1,5-Dichloro-2-Nitro-4-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 1,5 - dichloro - 2 - nitro - 4 - (trifluoromethyl)benzene packaged in a sealed bottle. |
| Storage | 1,5 - Dichloro - 2 - nitro - 4 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents, reducing agents, and other incompatible substances to avoid potential chemical reactions. |
| Shipping | 1,5 - Dichloro - 2 - nitro - 4 - (trifluoromethyl)benzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, ensuring safe transport to prevent any spills or environmental hazards. |
Competitive 1,5-Dichloro-2-Nitro-4-(Trifluoromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1,5-Dichloro-2-Nitro-4-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1,5-dichloro-2-nitro-4- (trifluoromethyl) benzene?
1% 2C5-dioxo-2-piperidin-4- (trifluoromethyl) benzene, which has a wide range of uses. In the field of medicine, it is often used as a key intermediate to help create a variety of specific drugs. For example, when developing new antidepressants, its unique chemical structure can precisely act on specific targets in the nervous system, improving drug efficacy and pertinence. In the field of pesticides, it can be used as an active ingredient or an important synthetic raw material. With its own chemical properties, it can effectively kill pests, inhibit the growth of pathogens, build a protective barrier for crop growth, and ensure agricultural harvest. In the field of materials science, it also has a place. It can participate in the synthesis of special polymer materials, endowing materials with unique properties such as excellent thermal stability, chemical stability and mechanical properties, thereby expanding the scope of material applications and meeting the strict requirements of materials in different fields. With its unique structure and characteristics, this compound plays an indispensable role in many fields such as medicine, pesticides and materials science, and is of great significance to promote the development of related fields.
What are the synthesis methods of 1,5-dichloro-2-nitro-4- (trifluoromethyl) benzene?
To prepare 1-2,5-dioxy-2-pyrrolid- 4- (triethoxy methyl) furan, the synthesis method is as follows:
The starting material can be selected from furan derivatives and pyrrole derivatives with suitable substituents. First, the furan derivative is modified to introduce a group that can react with pyrrole derivatives at a specific position.
In the reaction system, temperature, pH and other conditions are regulated. Appropriate solvents, such as dichloromethane, N, N-dimethylformamide, etc. can be selected to facilitate the reaction. If it is catalyzed by base, potassium carbonate, sodium hydroxide, etc. can be selected to promote the reaction to proceed in the desired direction.
First, the furan derivative containing a specific substituent is reacted with a suitable reagent to form an active intermediate. This active intermediate needs to be properly protected and treated to prevent side reactions from occurring. At the same time, the pyrrole derivative is pretreated to activate a specific check point.
Then, under carefully prepared reaction conditions, the pretreated furan derivative active intermediate interacts with the pyrrole derivative. During the reaction, the reaction process is closely monitored, which can be monitored by means of thin-layer chromatography.
When the reaction is generally completed, the reaction mixture is separated and purified. First, by extraction, the difference in the solubility of the product and impurities in different solvents is initially separated. After column chromatography, suitable stationary phase and mobile phase were selected to further purify the product to obtain high purity 1-2,5-dioxy-2-pyrrolyl-4 - (triethoxymethyl) furan.
The starting material can be selected from furan derivatives and pyrrole derivatives with suitable substituents. First, the furan derivative is modified to introduce a group that can react with pyrrole derivatives at a specific position.
In the reaction system, temperature, pH and other conditions are regulated. Appropriate solvents, such as dichloromethane, N, N-dimethylformamide, etc. can be selected to facilitate the reaction. If it is catalyzed by base, potassium carbonate, sodium hydroxide, etc. can be selected to promote the reaction to proceed in the desired direction.
First, the furan derivative containing a specific substituent is reacted with a suitable reagent to form an active intermediate. This active intermediate needs to be properly protected and treated to prevent side reactions from occurring. At the same time, the pyrrole derivative is pretreated to activate a specific check point.
Then, under carefully prepared reaction conditions, the pretreated furan derivative active intermediate interacts with the pyrrole derivative. During the reaction, the reaction process is closely monitored, which can be monitored by means of thin-layer chromatography.
When the reaction is generally completed, the reaction mixture is separated and purified. First, by extraction, the difference in the solubility of the product and impurities in different solvents is initially separated. After column chromatography, suitable stationary phase and mobile phase were selected to further purify the product to obtain high purity 1-2,5-dioxy-2-pyrrolyl-4 - (triethoxymethyl) furan.
What are the physical properties of 1,5-dichloro-2-nitro-4- (trifluoromethyl) benzene
1% 2C5-dioxy-2-furan-4- (trifluoromethyl) pyridine, this is an organic compound. Its physical properties are as follows:
Looking at its shape, under room temperature and pressure, it is mostly liquid, with good fluidity, just like smart water, and can easily change its own shape to fit the container. And the texture is uniform, without obvious particles or impurities, pure and clear, like crystal clear jade liquid.
Smell its smell, with a unique irritating smell, this smell is sharp and strong, just like a sharp sword, which can quickly stimulate the nasal mucosa, which is impressive. However, it should be noted that because of its irritation, excessive inhalation or damage to the human respiratory tract.
In terms of its solubility, it exhibits good solubility in organic solvents such as ethanol and ether. Just like salt is integrated into water, it can mix uniformly with organic solvents to form a uniform and stable solution. However, in water, its solubility is poor, and the two are like incompatible enemies, and it is difficult to blend.
Measure its boiling point, and it is in a specific temperature range. When the external temperature gradually rises to the boiling point, the compound will change from a liquid state to a gaseous state, just like ice into water, hydration into gas, and phase changes occur. This boiling point characteristic has important application value in the process of separation and purification of compounds.
Measuring its density, compared to water, may be different. Or greater than the density of water, if it is placed in the same container as water, it will sink to the bottom like a stone, sinking in the lower layer of water; or less than the density of water, it will float on the water surface, like oil floating in water.
1% 2C5-dioxo-2-furan-4 - (trifluoromethyl) pyridine These physical properties lay the foundation for its application in many fields such as chemical industry and medicine, and also provide a key reference for related research and practice.
Looking at its shape, under room temperature and pressure, it is mostly liquid, with good fluidity, just like smart water, and can easily change its own shape to fit the container. And the texture is uniform, without obvious particles or impurities, pure and clear, like crystal clear jade liquid.
Smell its smell, with a unique irritating smell, this smell is sharp and strong, just like a sharp sword, which can quickly stimulate the nasal mucosa, which is impressive. However, it should be noted that because of its irritation, excessive inhalation or damage to the human respiratory tract.
In terms of its solubility, it exhibits good solubility in organic solvents such as ethanol and ether. Just like salt is integrated into water, it can mix uniformly with organic solvents to form a uniform and stable solution. However, in water, its solubility is poor, and the two are like incompatible enemies, and it is difficult to blend.
Measure its boiling point, and it is in a specific temperature range. When the external temperature gradually rises to the boiling point, the compound will change from a liquid state to a gaseous state, just like ice into water, hydration into gas, and phase changes occur. This boiling point characteristic has important application value in the process of separation and purification of compounds.
Measuring its density, compared to water, may be different. Or greater than the density of water, if it is placed in the same container as water, it will sink to the bottom like a stone, sinking in the lower layer of water; or less than the density of water, it will float on the water surface, like oil floating in water.
1% 2C5-dioxo-2-furan-4 - (trifluoromethyl) pyridine These physical properties lay the foundation for its application in many fields such as chemical industry and medicine, and also provide a key reference for related research and practice.
What are the chemical properties of 1,5-dichloro-2-nitro-4- (trifluoromethyl) benzene
The chemical properties of 1% 2C5-dioxy-2-carbonyl-4- (trifluoromethyl) pyridine are quite rich. It has a certain stability due to the characteristics of some chemical bonds in the molecular structure.
From the perspective of reactivity, due to the presence of carbonyl groups, the compound is prone to react with nucleophiles. Nucleophiles can attack the carbon atoms of carbonyl groups, initiating reactions such as nucleophilic addition. For example, alcohol nucleophiles can react with them to form new compounds. This is because the electron cloud of carbon-oxygen double bonds in carbonyl groups is unevenly distributed, and the carbon atoms are partially positively charged and vulnerable to attack by nucleophiles.
Furthermore, the introduction of trifluoromethyl has a great impact on its chemical properties. Trifluoromethyl has strong electron-absorbing properties, which can reduce the electron cloud density of the pyridine ring. In this way, the electrophilic substitution activity on the pyridine ring changes, and the reaction check point and reaction difficulty are different compared with traditional pyridine. Generally speaking, electrophilic reagents tend to attack positions with relatively high electron cloud density.
The dioxy structure also affects its overall properties. This structure may affect the spatial configuration of the molecule, which in turn affects its interaction with other molecules. In some chemical reactions, the steric hindrance effect is highlighted by the presence of the dioxy structure, which affects the reaction rate and product selectivity.
In addition, the chemical properties of the compound may also change under different solvent environments. Polar and non-polar solvents both affect its solubility and reactivity. In polar solvents, the interaction between the solvent and the compound molecules may promote the progress of some ionic reactions.
In summary, the chemical properties of 1% 2C5-dioxo-2-carbonyl-4- (trifluoromethyl) pyridine are affected by the interaction of its various structural units. In the field of organic synthesis, these properties determine the behavior and application of its participation in various chemical reactions.
From the perspective of reactivity, due to the presence of carbonyl groups, the compound is prone to react with nucleophiles. Nucleophiles can attack the carbon atoms of carbonyl groups, initiating reactions such as nucleophilic addition. For example, alcohol nucleophiles can react with them to form new compounds. This is because the electron cloud of carbon-oxygen double bonds in carbonyl groups is unevenly distributed, and the carbon atoms are partially positively charged and vulnerable to attack by nucleophiles.
Furthermore, the introduction of trifluoromethyl has a great impact on its chemical properties. Trifluoromethyl has strong electron-absorbing properties, which can reduce the electron cloud density of the pyridine ring. In this way, the electrophilic substitution activity on the pyridine ring changes, and the reaction check point and reaction difficulty are different compared with traditional pyridine. Generally speaking, electrophilic reagents tend to attack positions with relatively high electron cloud density.
The dioxy structure also affects its overall properties. This structure may affect the spatial configuration of the molecule, which in turn affects its interaction with other molecules. In some chemical reactions, the steric hindrance effect is highlighted by the presence of the dioxy structure, which affects the reaction rate and product selectivity.
In addition, the chemical properties of the compound may also change under different solvent environments. Polar and non-polar solvents both affect its solubility and reactivity. In polar solvents, the interaction between the solvent and the compound molecules may promote the progress of some ionic reactions.
In summary, the chemical properties of 1% 2C5-dioxo-2-carbonyl-4- (trifluoromethyl) pyridine are affected by the interaction of its various structural units. In the field of organic synthesis, these properties determine the behavior and application of its participation in various chemical reactions.
Precautions for storage and transportation of 1,5-dichloro-2-nitro-4- (trifluoromethyl) benzene
1% 2C5-dioxo-2-furan-4- (trifluoromethyl) pyridine This compound needs to pay attention to the following key matters during storage and transportation.
First, because of its possible chemical activity and potential danger, it must be stored in a cool, dry and well-ventilated place. Avoid direct sunlight and close to heat sources to prevent thermal decomposition or other chemical reactions. If the storage environment humidity is high, it may cause the compound to be hydrolyzed by moisture, changing its chemical structure and properties, which will affect subsequent use.
Second, the choice of storage container is particularly important. Materials that can withstand the chemical properties of the compound, such as specific glass materials or corrosion-resistant plastic materials, should be selected to ensure that the container is well sealed and prevent compound leakage. If the container is not made properly, it may react with the compound, not only contaminating the compound, but also causing damage to the container, resulting in the risk of leakage.
Third, during transportation, proper packaging should be carried out in accordance with relevant regulations. Add necessary buffering and protective materials to avoid package damage due to vibration and collision. And the transportation vehicle needs to have suitable temperature control and ventilation conditions to maintain a stable transportation environment. If the package is damaged during transportation, the compound may leak, which may pose a threat to the environment and personnel safety.
Fourth, operators need to take protective measures. Whether it is storage operation or transportation loading and unloading, appropriate protective gloves, goggles and protective clothing should be worn to prevent the compound from coming into contact with the skin and eyes, because it may be irritating or toxic, and once exposed, it will cause harm to the human body.
Finally, whether it is a storage site or a transportation vehicle, it is necessary to be equipped with corresponding emergency treatment equipment and materials. For example, adsorbents are used to deal with leaked liquids, as well as corresponding first aid equipment and medicines, so that in case of emergencies, they can be quickly responded to and reduce the degree of harm.
First, because of its possible chemical activity and potential danger, it must be stored in a cool, dry and well-ventilated place. Avoid direct sunlight and close to heat sources to prevent thermal decomposition or other chemical reactions. If the storage environment humidity is high, it may cause the compound to be hydrolyzed by moisture, changing its chemical structure and properties, which will affect subsequent use.
Second, the choice of storage container is particularly important. Materials that can withstand the chemical properties of the compound, such as specific glass materials or corrosion-resistant plastic materials, should be selected to ensure that the container is well sealed and prevent compound leakage. If the container is not made properly, it may react with the compound, not only contaminating the compound, but also causing damage to the container, resulting in the risk of leakage.
Third, during transportation, proper packaging should be carried out in accordance with relevant regulations. Add necessary buffering and protective materials to avoid package damage due to vibration and collision. And the transportation vehicle needs to have suitable temperature control and ventilation conditions to maintain a stable transportation environment. If the package is damaged during transportation, the compound may leak, which may pose a threat to the environment and personnel safety.
Fourth, operators need to take protective measures. Whether it is storage operation or transportation loading and unloading, appropriate protective gloves, goggles and protective clothing should be worn to prevent the compound from coming into contact with the skin and eyes, because it may be irritating or toxic, and once exposed, it will cause harm to the human body.
Finally, whether it is a storage site or a transportation vehicle, it is necessary to be equipped with corresponding emergency treatment equipment and materials. For example, adsorbents are used to deal with leaked liquids, as well as corresponding first aid equipment and medicines, so that in case of emergencies, they can be quickly responded to and reduce the degree of harm.
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