1-Amino-3-Chloro-6-Methylbenzene
Linshang Chemical
HS Code |
364598 |
Chemical Formula | C7H8ClN |
Molecular Weight | 141.598 g/mol |
Appearance | Solid (usually) |
Melting Point | Data needed |
Boiling Point | Data needed |
Solubility In Water | Low solubility (estimated) |
Solubility In Organic Solvents | Soluble in some organic solvents (e.g., ethanol, acetone) |
Density | Data needed |
Odor | Characteristic aromatic odor (estimated) |
Flash Point | Data needed |
Stability | Stable under normal conditions, but may react with strong oxidizing agents |
As an accredited 1-Amino-3-Chloro-6-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500g of 1 - amino - 3 - chloro - 6 - methylbenzene packaged in a sealed plastic bag. |
Storage | 1 - amino - 3 - chloro - 6 - methylbenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames as it may be flammable. Keep it in a tightly sealed container to prevent exposure to air and moisture, which could potentially lead to chemical reactions. Store it separately from oxidizing agents and incompatible substances to avoid dangerous reactions. |
Shipping | 1 - amino - 3 - chloro - 6 - methylbenzene is a chemical. Shipping should follow strict hazardous material regulations. It must be properly packaged in leak - proof containers, labeled clearly, and transported by carriers licensed for such chemicals. |
Competitive 1-Amino-3-Chloro-6-Methylbenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 1-Amino-3-Chloro-6-Methylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In the field of medicinal chemistry, it is an important intermediate in organic synthesis. It can be used to synthesize a variety of drugs by adding specific functional groups through specific chemical reactions. For example, it can be used as a starting material to synthesize drugs with antibacterial activity through multi-step reactions. The amino groups, chlorine atoms and methyl groups in its structure play a key role in the reaction, or participate in the formation of chemical bonds, or affect the molecular spatial configuration to meet the needs of drug binding to targets.
In the field of materials science, it can be used to prepare functional materials. Due to the presence of amino groups, chlorine atoms and methyl groups, molecules are endowed with unique chemical properties and reactivity. For example, polymerization can be used to combine them with other monomers to prepare polymeric materials with special properties, such as materials that are adsorbent to specific substances or have optical activity, for use in sensors, optical devices and other fields.
In dye chemistry, 1-amino-3-chloro-6-methylbenzene is also useful. Its structure can introduce chromophore, and with appropriate chemical modification, dyes with rich color and good stability can be prepared. Amino groups can react with other compounds to build conjugated systems and enhance the color ability of dyes, while chlorine atoms and methyl groups can adjust the solubility and light resistance of dyes.
1-amino-3-chloro-6-methylbenzene, with its unique molecular structure, is an important basic raw material in many fields such as medicine, materials, dyes, etc., and contributes to the development of various fields.
1. ** Properties **: At room temperature, it is mostly colorless to light yellow liquid or solid. Due to the structure of the benzene ring, the intermolecular force makes the substance exhibit a relatively stable aggregate state.
2. ** Melting point and boiling point **: The melting point and boiling point are affected by the intermolecular force and structure. The benzene ring interacts with the amino group, chlorine atom, and methyl group, resulting in a specific range of melting points and boiling points. However, the exact value needs to be determined accurately by experiment. It is roughly speculated that the boiling point or at a higher temperature range requires more energy for gasification due to the interaction between the benzene ring and the polar group.
3. ** Solubility **: Because it is an organic compound and contains the non-polar structural part of the benzene ring, it has good solubility in organic solvents, such as common ethanol, ether, dichloromethane, etc. However, due to the presence of amino groups, it has a certain polarity, and its solubility in water is relatively limited, but it is slightly better than pure hydrocarbons.
4. ** Density **: Density is related to molecular structure and atomic composition. The benzene ring, amino group, chlorine atom, and methyl group constitute a specific molecular mass and spatial structure, and the density may be similar to that of common organic compounds. The specific value needs to be obtained by experimental measurement.
5. ** Odor **: Often has a special odor, originating from the benzene ring and functional groups such as amino groups and chlorine atoms. This odor or pungent, has a certain stimulation to the olfactory system, because the functional groups in the structure can interact with the olfactory receptors.
First talk about its amino properties. Amino (-NH2O) is a strong electron donor group, rich in electron clouds, and easily reacts with electrophilic reagents. For example, under suitable conditions, it can acylate with electrophilic reagents such as acyl chloride and anhydride, and the hydrogen on the amino nitrogen atom is replaced by an acyl group to form amide compounds. This reaction can be used to introduce carbonyl-containing functional groups on the benzene ring, and then derive various compounds. In drug synthesis, it is often used to construct active structural units.
Furthermore, chlorine atoms. Although chlorine atoms are electron-withdrawing groups, they have lone pairs of electrons, which affect the distribution of electron clouds in the benzene ring to a certain extent. It can undergo nucleophilic substitution reactions. When suitable nucleophilic reagents, such as sodium alcohol, phenol salts, etc., exist, chlorine atoms can be replaced by corresponding nucleophilic groups. When synthesizing benzene derivatives with specific structures, the required functional groups can be precisely introduced to achieve the construction of target molecules.
And methyl (-CH 🥰) as the power supply group can increase the electron cloud density of the benzene ring, especially the methyl ortho and para-sites. This leads to an increase in the activity of the electrophilic substitution of the benzene ring. When halogenation, nitrification, sulfonation and other electrophilic substitution reactions occur, it is more likely to introduce substituents at the methyl ortho and para-sites. For example, during nitrification, nitro (-NO ²) easily enters the ortho and para-sites of methyl. The various functional groups in 1-amino-3-chloro-6-methylbenzene interact with each other and jointly determine their chemical properties, providing a rich reaction check point for organic synthesis chemists to create organic compounds with different structures and functions.
First, it can be started with suitable aromatic hydrocarbons. First, take the aromatic hydrocarbon containing methyl, and use an appropriate halogenation reagent, such as chlorine gas. Under specific reaction conditions, such as suitable temperature and catalyst, a halogenation reaction is carried out to introduce chlorine atoms into the benzene ring to obtain aromatic hydrocarbons containing chlorine and methyl. Then, through nitration reaction, nitro is introduced at a specific position in the benzene ring. This process requires precise control of the reaction conditions, because the introduction position of nitro groups may vary under different conditions. The common nitrifying reagents used are mixed acids of concentrated nitric acid and concentrated sulfuric acid. After the introduction of the nitro group, the nitro group is converted into an amino group by reduction means, such as iron powder and hydrochloric acid, to obtain 1-amino-3-chloro-6-methylbenzene.
Second, other compounds that already contain some of the target substituents can also be used as raw materials. If the starting material contains chlorine atoms and a methyl-based benzene ring, the amino group can be introduced through an amination reaction. This amination reaction may require a specific catalyst and a suitable reaction medium. If a suitable metal catalyst is selected, in an organic solvent, under a certain temperature and pressure, the reactants are reacted with the amination reagent, so as to achieve the purpose of introducing amino groups at specific positions in the benzene ring, and the required 1-amino-3-chloro-6-methylbenzene is obtained.
Third, a strategy of gradually constructing the benzene ring can also be considered. Chain compounds containing chlorine, methyl and functional groups that can be converted into amino groups are first synthesized, and then the benzene ring structure is constructed by cyclization reaction. This process involves a multi-step reaction, and each step requires fine regulation of the reaction conditions to ensure that the reaction proceeds in the expected direction and finally successfully synthesizes 1-amino-3-chloro-6-methylbenzene.
All these synthesis methods have their own advantages and disadvantages. In practical applications, the appropriate synthesis path needs to be carefully selected according to the availability of raw materials, cost, difficulty in controlling reaction conditions and many other factors.
First words storage. This compound should be stored in a cool, dry and well-ventilated place. Because of the cool environment, it can avoid the acceleration of chemical reactions caused by heat, resulting in quality damage or danger. Dry place to prevent it from getting wet, because moisture can often cause many chemical reactions, affecting its stability. Well-ventilated, it can disperse harmful gases that may escape and keep the environment safe. And it should be kept away from fire and heat sources. Open flames and hot topics can easily cause the compound to explode. This is a serious problem and cannot be prevented. At the same time, it needs to be stored separately from oxidants and acids. These numbers are easy to chemically react with 1-amino-3-chloro-6-methylbenzene, and may be unpredictable when mixed.
Times and transportation. When transporting, the packaging must be firm. Solid packaging can prevent it from leaking due to collision and vibration during transportation. Transportation vehicles also need to be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment for emergencies. During driving, make sure that the container does not leak, collapse, fall, or damage. And the transportation process should follow the specified route, do not stop in densely populated areas and residential areas, in case of leakage and other accidents, endangering the safety of many people.
In short, the storage and transportation of 1-amino-3-chloro-6-methylbenzene is related to safety and quality, and all links need to be treated with caution, follow relevant norms, and must not be negligent.

Scan to WhatsApp