Linshang Chemical
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1-Amino-4-Chloro-2-Nitrobenzene
Linshang Chemical
|
HS Code |
537082 |
| Chemical Formula | C6H5ClN2O2 |
| Molar Mass | 172.57 g/mol |
| Appearance | Yellow to orange - red solid |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, acetone |
| Melting Point | 97 - 101 °C |
| Odor | Characteristic, pungent odor |
| Stability | Stable under normal conditions, but can react with strong oxidizing agents |
As an accredited 1-Amino-4-Chloro-2-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 1 - amino - 4 - chloro - 2 - nitrobenzene packaged in a sealed plastic bag. |
| Storage | 1 - amino - 4 - chloro - 2 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly - sealed container to prevent moisture and air exposure. Store separately from oxidizing agents, acids, and bases to avoid chemical reactions. Adhere to local safety regulations for proper storage. |
| Shipping | 1 - amino - 4 - chloro - 2 - nitrobenzene is a chemical. Ship it in well - sealed containers, compliant with hazardous chemical regulations. Use appropriate carriers ensuring proper handling to prevent spills and ensure safe transportation. |
Competitive 1-Amino-4-Chloro-2-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Amino-4-Chloro-2-Nitrobenzene in China?
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As a leading 1-Amino-4-Chloro-2-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1-amino-4-chloro-2-nitrobenzene?
1-Amino-4-chloro-2-nitrobenzene is 1-amino-4-chloro-2-nitrobenzene, which has a wide range of uses. In the dye industry, it can be regarded as an important intermediate. From this, many types of dyes can be prepared, such as azo dyes. Due to the specific chemical reaction of amino groups, chlorine atoms and nitro groups contained in the molecule, a rich and diverse hair color system can be constructed, which makes the dyes show brilliant colors and is widely used in fabric printing and dyeing and other fields to give fabrics a colorful color.
In the field of medicinal chemistry, 1-amino-4-chloro-2-nitrobenzene is also of key significance. It can be used as a starting material to prepare some compounds with specific pharmacological activities through multi-step reactions. Due to its unique structure, it can provide specific activity check points and spatial configurations for drug molecules, help drugs and biological targets to achieve precise binding, or interfere with specific physiological and biochemical processes in organisms, in order to achieve the effect of treating diseases.
Furthermore, in the field of pesticides, this compound also has its uses. The synthesis of some pesticides will use 1-amino-4-chloro-2-nitrobenzene as the base material. With the help of its chemical structure, pesticides that can effectively control pests can be designed and synthesized, which can affect the nervous system of pests or interfere with their growth and development process, thus effectively ensuring the healthy growth of crops and improving crop yield and quality.
In the field of medicinal chemistry, 1-amino-4-chloro-2-nitrobenzene is also of key significance. It can be used as a starting material to prepare some compounds with specific pharmacological activities through multi-step reactions. Due to its unique structure, it can provide specific activity check points and spatial configurations for drug molecules, help drugs and biological targets to achieve precise binding, or interfere with specific physiological and biochemical processes in organisms, in order to achieve the effect of treating diseases.
Furthermore, in the field of pesticides, this compound also has its uses. The synthesis of some pesticides will use 1-amino-4-chloro-2-nitrobenzene as the base material. With the help of its chemical structure, pesticides that can effectively control pests can be designed and synthesized, which can affect the nervous system of pests or interfere with their growth and development process, thus effectively ensuring the healthy growth of crops and improving crop yield and quality.
What are the physical properties of 1-amino-4-chloro-2-nitrobenzene?
1 - amino - 4 - chloro - 2 - nitrobenzene is an organic compound with unique physical properties. In terms of color state, it often takes the shape of a light yellow to brown crystalline powder. This form is quite common in many organic synthesis products. The arrangement of molecular structures results in a specific form of intermolecular forces, resulting in this appearance.
The melting point is between about 108-112 ° C. The value of the melting point is determined by factors such as intermolecular forces, hydrogen bonds, and lattice energy. There are amino groups, chlorine atoms, and nitro groups in the molecules of this compound. The interaction between these groups forms a specific lattice structure, giving it a corresponding melting point.
Solubility is also an important property. It is extremely difficult to dissolve in water because it is an organic compound with hydrophobicity, and the intermolecular force between water molecules and the compound is much weaker than the intermolecular force of the compound. However, it has a certain solubility in common organic solvents such as ethanol, ether, and acetone, because these organic solvents can form similar intermolecular forces with the compound, following the principle of similar compatibility.
In addition, its density is about 1.57 g/cm ³, and the density depends on the molecular weight and the way of molecular accumulation. The compound molecule contains groups with relatively large mass such as chlorine atoms and nitro groups, and the molecules are closely arranged, so the density is relatively high.
The physical properties of this compound are of great significance in the fields of organic synthesis and drug development. For example, melting point properties can help determine its purity, while solubility affects its dispersion in the reaction system and the degree of participation in the reaction.
The melting point is between about 108-112 ° C. The value of the melting point is determined by factors such as intermolecular forces, hydrogen bonds, and lattice energy. There are amino groups, chlorine atoms, and nitro groups in the molecules of this compound. The interaction between these groups forms a specific lattice structure, giving it a corresponding melting point.
Solubility is also an important property. It is extremely difficult to dissolve in water because it is an organic compound with hydrophobicity, and the intermolecular force between water molecules and the compound is much weaker than the intermolecular force of the compound. However, it has a certain solubility in common organic solvents such as ethanol, ether, and acetone, because these organic solvents can form similar intermolecular forces with the compound, following the principle of similar compatibility.
In addition, its density is about 1.57 g/cm ³, and the density depends on the molecular weight and the way of molecular accumulation. The compound molecule contains groups with relatively large mass such as chlorine atoms and nitro groups, and the molecules are closely arranged, so the density is relatively high.
The physical properties of this compound are of great significance in the fields of organic synthesis and drug development. For example, melting point properties can help determine its purity, while solubility affects its dispersion in the reaction system and the degree of participation in the reaction.
What is the chemistry of 1-amino-4-chloro-2-nitrobenzene?
1-Amino-4-chloro-2-nitrobenzene, Chinese name 1-amino-4-chloro-2-nitrobenzene, is one of the organic compounds. Its chemical properties are unique and valuable for investigation.
This compound contains amino group (-NH ²), chlorine atom (-Cl) and nitro group (-NO ³). The amino group is the power supply group, which can enhance the electron cloud density of the benzene ring and make the benzene ring more prone to electrophilic substitution. However, the nitro group is a strong electron-absorbing group, which will reduce the electron cloud density of the benzene ring and make the electrophilic substitution reaction difficult. These two groups coexist in the benzene ring and interact to affect the reactivity and selectivity of the compound.
From the perspective of electrophilic substitution reaction, the density of the electron cloud of the amino group is relatively high, and the electrophilic reagents are easy to attack this position. However, the presence of nitro groups will weaken the activation of the amino group, and the reactivity is not a simple superposition of two groups. Chlorine atoms have relatively little effect on the electron cloud density of the benzene ring, and belong to the ortho and para-localization groups.
In the redox reaction, nitro groups can be reduced to amino groups, etc. In case of suitable reducing agents, the nitro group of 1-amino-4-chloro-2-nitrobenzene may be converted to amino groups to obtain diamino compounds. The amino group can be oxidized under specific conditions, resulting in changes in the structure and properties of the compound.
In terms of solubility, it has a certain solubility in polar solvents such as ethanol and acetone due to the presence of polar groups, but its solubility in water is limited due to the presence of benzene rings.
1-amino-4-chloro-2-nitrobenzene has complex chemical properties, and the interaction of each group determines its performance in various chemical reactions. It has an important position and diverse applications in organic synthesis and other fields.
This compound contains amino group (-NH ²), chlorine atom (-Cl) and nitro group (-NO ³). The amino group is the power supply group, which can enhance the electron cloud density of the benzene ring and make the benzene ring more prone to electrophilic substitution. However, the nitro group is a strong electron-absorbing group, which will reduce the electron cloud density of the benzene ring and make the electrophilic substitution reaction difficult. These two groups coexist in the benzene ring and interact to affect the reactivity and selectivity of the compound.
From the perspective of electrophilic substitution reaction, the density of the electron cloud of the amino group is relatively high, and the electrophilic reagents are easy to attack this position. However, the presence of nitro groups will weaken the activation of the amino group, and the reactivity is not a simple superposition of two groups. Chlorine atoms have relatively little effect on the electron cloud density of the benzene ring, and belong to the ortho and para-localization groups.
In the redox reaction, nitro groups can be reduced to amino groups, etc. In case of suitable reducing agents, the nitro group of 1-amino-4-chloro-2-nitrobenzene may be converted to amino groups to obtain diamino compounds. The amino group can be oxidized under specific conditions, resulting in changes in the structure and properties of the compound.
In terms of solubility, it has a certain solubility in polar solvents such as ethanol and acetone due to the presence of polar groups, but its solubility in water is limited due to the presence of benzene rings.
1-amino-4-chloro-2-nitrobenzene has complex chemical properties, and the interaction of each group determines its performance in various chemical reactions. It has an important position and diverse applications in organic synthesis and other fields.
What are 1-amino-4-chloro-2-nitrobenzene synthesis methods?
1-Amino-4-chloro-2-nitrobenzene is an important intermediate in organic synthesis. Its synthesis methods have been investigated in ancient and modern times. The following is your detailed description.
The ancient method depends on the reaction between chemical reagents. First, chlorobenzene is often used as the starting material. The nitro group is introduced through the nitrification reaction of chlorobenzene. This reaction requires the selection of suitable nitrification reagents, such as mixed acid (mixture of nitric acid and sulfuric acid), and the control of temperature, ratio and other conditions, so that the nitro group is introduced into the specific position of the benzene ring to obtain 4-chloro-2-nitrobenzene. Then, the nitro group is converted into an amino group by reduction. The commonly used reducing agents in the past, such as the combination of iron filings and hydrochloric acid, have undergone complex chemical changes. Iron filings generate new hydrogen under the action of hydrochloric acid. This hydrogen has strong reducing properties and can gradually reduce the nitro group to an amino group, resulting in 1-amino-4-chloro-2-nitrobenzene. However, this method is complicated to operate and produces a lot of iron sludge and other wastes, which are mostly unfavorable to the environment.
Today's method has become more and more advanced with the advance of science and technology. One is catalytic hydrogenation. Using 4-chloro-2-nitrobenzene as the substrate, select a suitable catalyst, such as supported metal catalysts (palladium carbon, platinum carbon, etc.), in a hydrogen atmosphere, under specific temperature and pressure conditions, the nitro group is successfully converted into an amino group through catalytic hydrogenation. This method has relatively mild reaction conditions, high product purity, and less waste, which is in line with today's green chemistry concept. Second, there are also methods for synthesizing coupling reactions catalyzed by transition metals. By designing a specific reaction path, the structure of 1-amino-4-chloro-2-nitrobenzene is precisely constructed by halogenated aromatics and amino-containing reagents under the action of transition metal (such as copper, palladium, etc.) catalysts. This method has good selectivity and can effectively avoid unnecessary side reactions. It is very popular in the field of organic synthesis.
The ancient method depends on the reaction between chemical reagents. First, chlorobenzene is often used as the starting material. The nitro group is introduced through the nitrification reaction of chlorobenzene. This reaction requires the selection of suitable nitrification reagents, such as mixed acid (mixture of nitric acid and sulfuric acid), and the control of temperature, ratio and other conditions, so that the nitro group is introduced into the specific position of the benzene ring to obtain 4-chloro-2-nitrobenzene. Then, the nitro group is converted into an amino group by reduction. The commonly used reducing agents in the past, such as the combination of iron filings and hydrochloric acid, have undergone complex chemical changes. Iron filings generate new hydrogen under the action of hydrochloric acid. This hydrogen has strong reducing properties and can gradually reduce the nitro group to an amino group, resulting in 1-amino-4-chloro-2-nitrobenzene. However, this method is complicated to operate and produces a lot of iron sludge and other wastes, which are mostly unfavorable to the environment.
Today's method has become more and more advanced with the advance of science and technology. One is catalytic hydrogenation. Using 4-chloro-2-nitrobenzene as the substrate, select a suitable catalyst, such as supported metal catalysts (palladium carbon, platinum carbon, etc.), in a hydrogen atmosphere, under specific temperature and pressure conditions, the nitro group is successfully converted into an amino group through catalytic hydrogenation. This method has relatively mild reaction conditions, high product purity, and less waste, which is in line with today's green chemistry concept. Second, there are also methods for synthesizing coupling reactions catalyzed by transition metals. By designing a specific reaction path, the structure of 1-amino-4-chloro-2-nitrobenzene is precisely constructed by halogenated aromatics and amino-containing reagents under the action of transition metal (such as copper, palladium, etc.) catalysts. This method has good selectivity and can effectively avoid unnecessary side reactions. It is very popular in the field of organic synthesis.
1-amino-4-chloro-2-nitrobenzene what are the precautions during use
1 - amino - 4 - chloro - 2 - nitrobenzene is an organic compound. During its use, the following numbers should be paid attention to:
First, it is related to safety protection. This compound has certain toxicity and irritation, and can cause harm to human health. When taking it, be sure to wear suitable protective equipment, such as gloves, goggles, protective clothing, etc., to prevent skin contact, eye splashing and inhalation of dust or steam. The operation should be carried out in a well-ventilated environment, preferably in a fume hood. If it is inadvertently touched, rinse with plenty of water immediately and seek medical attention according to the specific situation.
Second, about storage conditions. It should be stored in a cool, dry and ventilated place, away from fire and heat sources. Because it is an organic compound, in case of open flame, hot topic or oxidant, there is a risk of ignition and explosion. At the same time, it should be stored separately from oxidants, acids, bases, etc., and must not be mixed to prevent chemical reactions.
Third, it involves usage specifications. Before use, it is necessary to understand its physical and chemical properties in detail, such as melting point, boiling point, solubility, etc., in order to rationally plan the use process. During use, strictly control the reaction conditions, such as temperature, pressure, reaction time, etc., to precisely control the reaction process and improve the purity and yield of the product. And according to the specific reaction and use, choose appropriate solvents and reaction reagents to avoid unnecessary side reactions.
Fourth, pay attention to environmental protection. After use, the waste containing this compound should be properly disposed of in accordance with relevant laws and regulations, and must not be discharged at will. Because it may cause pollution to the environment and destroy the ecological balance. When disposing of waste, appropriate methods such as chemical treatment and incineration can be used to ensure its harmlessness.
First, it is related to safety protection. This compound has certain toxicity and irritation, and can cause harm to human health. When taking it, be sure to wear suitable protective equipment, such as gloves, goggles, protective clothing, etc., to prevent skin contact, eye splashing and inhalation of dust or steam. The operation should be carried out in a well-ventilated environment, preferably in a fume hood. If it is inadvertently touched, rinse with plenty of water immediately and seek medical attention according to the specific situation.
Second, about storage conditions. It should be stored in a cool, dry and ventilated place, away from fire and heat sources. Because it is an organic compound, in case of open flame, hot topic or oxidant, there is a risk of ignition and explosion. At the same time, it should be stored separately from oxidants, acids, bases, etc., and must not be mixed to prevent chemical reactions.
Third, it involves usage specifications. Before use, it is necessary to understand its physical and chemical properties in detail, such as melting point, boiling point, solubility, etc., in order to rationally plan the use process. During use, strictly control the reaction conditions, such as temperature, pressure, reaction time, etc., to precisely control the reaction process and improve the purity and yield of the product. And according to the specific reaction and use, choose appropriate solvents and reaction reagents to avoid unnecessary side reactions.
Fourth, pay attention to environmental protection. After use, the waste containing this compound should be properly disposed of in accordance with relevant laws and regulations, and must not be discharged at will. Because it may cause pollution to the environment and destroy the ecological balance. When disposing of waste, appropriate methods such as chemical treatment and incineration can be used to ensure its harmlessness.
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