Linshang Chemical
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1-Amino-4-Chloro-6-Methylbenzene
Linshang Chemical
|
HS Code |
547816 |
| Chemical Formula | C7H8ClN |
| Appearance | Solid (likely a white to off - white powder) |
| Solubility In Water | Low solubility (aromatic amines generally have low water solubility) |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, acetone |
| Odor | May have a characteristic amine - like odor |
| Stability | Stable under normal conditions, but may react with strong oxidizing agents |
As an accredited 1-Amino-4-Chloro-6-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - amino - 4 - chloro - 6 - methylbenzene: Packed in 5 - kg bags for chemical storage and transport. |
| Storage | 1 - amino - 4 - chloro - 6 - methylbenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store it in a tightly sealed container to prevent leakage and exposure to air and moisture. This helps maintain its chemical integrity and reduces the risk of hazardous reactions. |
| Shipping | 1 - amino - 4 - chloro - 6 - methylbenzene is shipped in sealed, corrosion - resistant containers. Compliance with chemical transportation regulations is ensured, with proper labeling indicating its nature to safeguard handlers and during transit. |
Competitive 1-Amino-4-Chloro-6-Methylbenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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As a leading 1-Amino-4-Chloro-6-Methylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the Chinese name of 1-amino-4-chloro-6-methylbenzene?
1-Amino-4-chloro-6-methylbenzene, this is the name of an organic compound. According to the rules of organic chemical nomenclature, the benzene ring is used as the parent body, and the substituent positions are first marked with numbers, and then the substituent names are listed in the order of simplification and then complexity. This compound has an amino group (-NH2O), a chlorine atom (-Cl) and a methyl group (-CH 🥰) on the benzene ring. The amino group is in the 1st position, the chlorine atom is in the 4th position, and the methyl group is in the 6th position, hence the name.
Looking at its structure, the benzene ring is a six-membered ring with a conjugated system, which is very stable. The nitrogen atom in the amino group has a lone pair of electrons, which can be conjugated with the benzene ring, which increases the electron cloud density of the benzene ring and makes the electrophilic substitution activity stronger. Chlorine atoms have an electron-absorbing induction effect, but they have a conjugation effect on the electron cloud density of the benzene ring, which has a complex effect on the electron cloud density of the benzene ring as a whole. Methyl is the power supply group, which can increase the electron cloud density of the benzene ring.
This compound has an extraordinary effect in the field of organic synthesis. It can be used as an intermediate to synthesize many drugs and dyes. For example, in drug research and development, it can be chemically reacted and connected with other functional groups to produce specific pharmacologically active compounds. And in the preparation of dyes, due
Looking at its structure, the benzene ring is a six-membered ring with a conjugated system, which is very stable. The nitrogen atom in the amino group has a lone pair of electrons, which can be conjugated with the benzene ring, which increases the electron cloud density of the benzene ring and makes the electrophilic substitution activity stronger. Chlorine atoms have an electron-absorbing induction effect, but they have a conjugation effect on the electron cloud density of the benzene ring, which has a complex effect on the electron cloud density of the benzene ring as a whole. Methyl is the power supply group, which can increase the electron cloud density of the benzene ring.
This compound has an extraordinary effect in the field of organic synthesis. It can be used as an intermediate to synthesize many drugs and dyes. For example, in drug research and development, it can be chemically reacted and connected with other functional groups to produce specific pharmacologically active compounds. And in the preparation of dyes, due
What are the main uses of 1-amino-4-chloro-6-methylbenzene?
1-Amino-4-chloro-6-methylbenzene, Chinese name 1-amino-4-chloro-6-methylbenzene, this compound has a wide range of uses.
In the field of medicine, it is often used as a key intermediate in the synthesis of many specific drugs. The compound has a unique structure and can endow the synthesized drug with specific biological activities and pharmacological properties. For example, when synthesizing some antimalarial drugs, 1-amino-4-chloro-6-methylbenzene can introduce specific groups through a series of reactions to build a structure that is compatible with the target of the malaria parasite, and then exert the anti-malarial effect.
In the field of pesticides, it is also an important raw material. It can synthesize a variety of high-efficiency pesticides, fungicides and other pesticide products. Due to its chemical properties, it can participate in the reaction to generate molecular structures with insecticidal and bactericidal activities. For example, the synthesis of certain pesticides that target specific pests or pathogens relies on the interaction of molecular structures with specific receptors or enzymes in the body of pests and pathogens to interfere with their normal physiological activities and achieve control purposes.
In the field of materials science, it also has applications. Or it is used to synthesize special polymer materials. By polymerizing with other monomers, its structural units are introduced into the polymer chain to give the material special properties. For example, improving the heat resistance and corrosion resistance of the material. By ingeniously designing and reacting, the material can meet the needs of special environments or specific application scenarios
In addition, in the dye industry, it can be used as an intermediate for synthetic dyes. Through chemical reactions, it is converted into dye molecules with specific colors and dyeing properties. Due to the existence of amino groups, chlorine atoms and methyl groups in the molecular structure, the electron cloud distribution and absorption spectrum of dye molecules are affected, thus presenting different colors to meet various dyeing needs.
1-Amino-4-chloro-6-methylbenzene plays a key role in the fields of medicine, pesticides, materials science and dye industry, promoting the development and technological progress of related industries.
In the field of medicine, it is often used as a key intermediate in the synthesis of many specific drugs. The compound has a unique structure and can endow the synthesized drug with specific biological activities and pharmacological properties. For example, when synthesizing some antimalarial drugs, 1-amino-4-chloro-6-methylbenzene can introduce specific groups through a series of reactions to build a structure that is compatible with the target of the malaria parasite, and then exert the anti-malarial effect.
In the field of pesticides, it is also an important raw material. It can synthesize a variety of high-efficiency pesticides, fungicides and other pesticide products. Due to its chemical properties, it can participate in the reaction to generate molecular structures with insecticidal and bactericidal activities. For example, the synthesis of certain pesticides that target specific pests or pathogens relies on the interaction of molecular structures with specific receptors or enzymes in the body of pests and pathogens to interfere with their normal physiological activities and achieve control purposes.
In the field of materials science, it also has applications. Or it is used to synthesize special polymer materials. By polymerizing with other monomers, its structural units are introduced into the polymer chain to give the material special properties. For example, improving the heat resistance and corrosion resistance of the material. By ingeniously designing and reacting, the material can meet the needs of special environments or specific application scenarios
In addition, in the dye industry, it can be used as an intermediate for synthetic dyes. Through chemical reactions, it is converted into dye molecules with specific colors and dyeing properties. Due to the existence of amino groups, chlorine atoms and methyl groups in the molecular structure, the electron cloud distribution and absorption spectrum of dye molecules are affected, thus presenting different colors to meet various dyeing needs.
1-Amino-4-chloro-6-methylbenzene plays a key role in the fields of medicine, pesticides, materials science and dye industry, promoting the development and technological progress of related industries.
What are the physical properties of 1-amino-4-chloro-6-methylbenzene?
1-Amino-4-chloro-6-methylbenzene is also a chemical substance. Its physical reason is important, and it is described in this article.
First of all, its external appearance is often solid, but it may also be changed due to environmental conditions. The color is more similar to white or slightly light color, which is caused by the action of its molecules.
And melting, 1-amino-4-chloro-6-methylbenzene has a specific melting force. Molecular forces, such as force, van der force, etc., determine the degree of stability from solid to liquid. The value of this melting is one of the important indicators for determining this substance.
Furthermore, the boiling process. The boiling process reflects the energy required for the material to be removed from the liquid. The amount, properties, and molecular forces of the molecule all affect the boiling process. The boiling process of 1-amino-4-chloro-6-methylbenzene allows us to know at what degree it can be vaporized, which is essential for chemical processes, fractionation, etc.
Solubility is also an important physical property. It has good solubility in solutions such as ethanol and ether. This is because the soluble 1-amino-4-chloro-6-methylbenzene molecule can form a similar force, following the principle of "similar miscibility". In water, its solubility is poor, and its molecular solubility is low.
In addition, the density cannot be ignored. The density of 1-amino-4-chloro-6-methylbenzene indicates the amount of this substance at the low position. This property is necessary to consider in the storage, storage, and anti-storage systems.
Therefore, the physical rationality of 1 - amino - 4 - chloro - 6 - methylbenzene, such as externality, melting and boiling, solubility, density, etc., are mutually important in chemical research, engineering and other fields. It is important to help us understand this material in depth and make good use of it.
First of all, its external appearance is often solid, but it may also be changed due to environmental conditions. The color is more similar to white or slightly light color, which is caused by the action of its molecules.
And melting, 1-amino-4-chloro-6-methylbenzene has a specific melting force. Molecular forces, such as force, van der force, etc., determine the degree of stability from solid to liquid. The value of this melting is one of the important indicators for determining this substance.
Furthermore, the boiling process. The boiling process reflects the energy required for the material to be removed from the liquid. The amount, properties, and molecular forces of the molecule all affect the boiling process. The boiling process of 1-amino-4-chloro-6-methylbenzene allows us to know at what degree it can be vaporized, which is essential for chemical processes, fractionation, etc.
Solubility is also an important physical property. It has good solubility in solutions such as ethanol and ether. This is because the soluble 1-amino-4-chloro-6-methylbenzene molecule can form a similar force, following the principle of "similar miscibility". In water, its solubility is poor, and its molecular solubility is low.
In addition, the density cannot be ignored. The density of 1-amino-4-chloro-6-methylbenzene indicates the amount of this substance at the low position. This property is necessary to consider in the storage, storage, and anti-storage systems.
Therefore, the physical rationality of 1 - amino - 4 - chloro - 6 - methylbenzene, such as externality, melting and boiling, solubility, density, etc., are mutually important in chemical research, engineering and other fields. It is important to help us understand this material in depth and make good use of it.
What are the chemical properties of 1-amino-4-chloro-6-methylbenzene?
1-Amino-4-chloro-6-methylbenzene, Chinese name 1-amino-4-chloro-6-methylbenzene, has unique chemical properties and appears in various chemical changes.
This compound contains an amino group (\ (- NH_ {2}\)), the amino group is rich in electrons and has significant nucleophilicity. In the case of electrophilic reagents, the amino group is easy to supply the electron pair and participate in the reaction itself. If it encounters the acyl halogen, the amino nitrogen atom will launch a nucleophilic attack on the carbonyl carbon of the acyl halogen to form amides. This reaction is often used in organic synthesis to construct complex molecules containing amide bonds.
Chlorine atom (\ (-Cl\)) is connected to the benzene ring, although the electron cloud density of the benzene ring is reduced, the electrophilic substitution activity of the benzene ring is inferior to that of benzene, but because of its induction effect, the electron cloud density of the ortho and para-position can be relatively high, so the electrophilic reagents still tend to attack the ortho and para-position of the chlorine atom. For example, when nitrification occurs, the nitro group (\ (- NO_ {2}\)) is more likely to enter the ortho and para-position of the chlorine atom.
methyl (\ (- CH_ {3}\)) is connected to the benzene ring, which is the power supply sub-group, which can increase the electron cloud density of the benzene ring and improve the When 1-amino-4-chloro-6-methylbenzene is sulfonated, the sulfonic acid group (\ (- SO_ {3} H\)) is mostly introduced into the methyl ortho and para-sites.
In addition, amino groups can participate in the diazotization reaction. In low temperature and strong acid environment, the amino group of 1-amino-4-chloro-6-methylbenzene can interact with nitrous acid to form diazonium salts. Diazonium salts are active and can undergo many transformations, such as being replaced by hydroxyl groups, halogens, cyanos, etc., providing various pathways for organic synthesis.
1-amino-4-chloro-6-methylbenzene is widely used in the field of organic synthesis due to its rich chemical properties due to the interaction of amino groups, chlorine atoms, methyl and other functional groups. It can prepare complex organic compounds through various reactions.
This compound contains an amino group (\ (- NH_ {2}\)), the amino group is rich in electrons and has significant nucleophilicity. In the case of electrophilic reagents, the amino group is easy to supply the electron pair and participate in the reaction itself. If it encounters the acyl halogen, the amino nitrogen atom will launch a nucleophilic attack on the carbonyl carbon of the acyl halogen to form amides. This reaction is often used in organic synthesis to construct complex molecules containing amide bonds.
Chlorine atom (\ (-Cl\)) is connected to the benzene ring, although the electron cloud density of the benzene ring is reduced, the electrophilic substitution activity of the benzene ring is inferior to that of benzene, but because of its induction effect, the electron cloud density of the ortho and para-position can be relatively high, so the electrophilic reagents still tend to attack the ortho and para-position of the chlorine atom. For example, when nitrification occurs, the nitro group (\ (- NO_ {2}\)) is more likely to enter the ortho and para-position of the chlorine atom.
methyl (\ (- CH_ {3}\)) is connected to the benzene ring, which is the power supply sub-group, which can increase the electron cloud density of the benzene ring and improve the When 1-amino-4-chloro-6-methylbenzene is sulfonated, the sulfonic acid group (\ (- SO_ {3} H\)) is mostly introduced into the methyl ortho and para-sites.
In addition, amino groups can participate in the diazotization reaction. In low temperature and strong acid environment, the amino group of 1-amino-4-chloro-6-methylbenzene can interact with nitrous acid to form diazonium salts. Diazonium salts are active and can undergo many transformations, such as being replaced by hydroxyl groups, halogens, cyanos, etc., providing various pathways for organic synthesis.
1-amino-4-chloro-6-methylbenzene is widely used in the field of organic synthesis due to its rich chemical properties due to the interaction of amino groups, chlorine atoms, methyl and other functional groups. It can prepare complex organic compounds through various reactions.
What are the preparation methods of 1-amino-4-chloro-6-methylbenzene?
1-Amino-4-chloro-6-methylbenzene. There are various methods for preparing this substance.
One can be obtained by reduction of the corresponding nitro compound. First, a suitable substitution reaction is used to introduce the benzene ring into the nitro group, chlorine atom and methyl group to obtain 1-nitro-4-chloro-6-methylbenzene. If toluene is used as the starting material, under appropriate conditions, after a halogenation reaction, the chlorine atom is substituted for the hydrogen at a specific position on the benzene ring, and then nitrified to introduce the nitro group at the specified position. Then, a suitable reducing agent is selected, such as iron and hydrochloric acid system, or hydrogen under the action of catalyst (such as palladium carbon), the nitro group is reduced to amino group, and then 1-amino-4-chloro-6-methylbenzene is obtained.
Second, it is prepared by the diazonium salt method. First, aniline derivatives containing chlorine and methyl, such as 4-chloro-6-methylaniline, are obtained. It reacts with nitrous acid at low temperature and acidic conditions to form a diazonium salt. After a suitable substitution reaction, the diazo group is replaced by a suitable group, and the final product is 1-amino-4-chloro-6-methylbenzene. For example, the reaction of diazo salts with certain metal salts or other reagents can be used to achieve the desired conversion.
Third, the Grignard reagent method can also be used. First, a halogenated aromatic hydrocarbon containing chlorine and methyl is prepared to react with magnesium to form a Grignard reagent. Then, this Grignard reagent reacts with a suitable nitrogenous compound to introduce an amino group. After subsequent treatment, 1-amino-4-chloro-6-methylbenzene can be obtained. During the reaction process, attention should be paid to the control of reaction conditions, such as anhydrous environment, suitable temperature and reaction time, etc., to ensure the smooth progress of the reaction and improve the yield and purity of the product.
Various preparation methods have their own advantages and disadvantages. In actual preparation, when considering factors such as the availability of raw materials, cost, difficulty of reaction conditions and requirements for product purity, the choice is made.
One can be obtained by reduction of the corresponding nitro compound. First, a suitable substitution reaction is used to introduce the benzene ring into the nitro group, chlorine atom and methyl group to obtain 1-nitro-4-chloro-6-methylbenzene. If toluene is used as the starting material, under appropriate conditions, after a halogenation reaction, the chlorine atom is substituted for the hydrogen at a specific position on the benzene ring, and then nitrified to introduce the nitro group at the specified position. Then, a suitable reducing agent is selected, such as iron and hydrochloric acid system, or hydrogen under the action of catalyst (such as palladium carbon), the nitro group is reduced to amino group, and then 1-amino-4-chloro-6-methylbenzene is obtained.
Second, it is prepared by the diazonium salt method. First, aniline derivatives containing chlorine and methyl, such as 4-chloro-6-methylaniline, are obtained. It reacts with nitrous acid at low temperature and acidic conditions to form a diazonium salt. After a suitable substitution reaction, the diazo group is replaced by a suitable group, and the final product is 1-amino-4-chloro-6-methylbenzene. For example, the reaction of diazo salts with certain metal salts or other reagents can be used to achieve the desired conversion.
Third, the Grignard reagent method can also be used. First, a halogenated aromatic hydrocarbon containing chlorine and methyl is prepared to react with magnesium to form a Grignard reagent. Then, this Grignard reagent reacts with a suitable nitrogenous compound to introduce an amino group. After subsequent treatment, 1-amino-4-chloro-6-methylbenzene can be obtained. During the reaction process, attention should be paid to the control of reaction conditions, such as anhydrous environment, suitable temperature and reaction time, etc., to ensure the smooth progress of the reaction and improve the yield and purity of the product.
Various preparation methods have their own advantages and disadvantages. In actual preparation, when considering factors such as the availability of raw materials, cost, difficulty of reaction conditions and requirements for product purity, the choice is made.
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