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1-Bromo-2,6-Dichloro-4-Fluorobenzene
|
HS Code |
319840 |
| Chemical Formula | C6H2BrCl2F |
| Molecular Weight | 243.888 |
| Appearance | Solid (Typical) |
| Boiling Point | Approx. 215 - 220 °C |
| Melting Point | Approx. 38 - 42 °C |
| Density | Approx. 1.8 g/cm³ |
| Solubility In Water | Low solubility |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Vapor Pressure | Low at room temperature |
| Flash Point | Approx. 90 - 95 °C |
| Stability | Stable under normal conditions |
As an accredited 1-Bromo-2,6-Dichloro-4-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 1 - bromo - 2,6 - dichloro - 4 - fluorobenzene in sealed chemical - grade vial. |
| Storage | 1 - Bromo - 2,6 - dichloro - 4 - fluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials, to prevent leakage and exposure to air and moisture, which could potentially lead to chemical reactions or degradation. |
| Shipping | 1 - bromo - 2,6 - dichloro - 4 - fluorobenzene is shipped in properly sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations to ensure safe transportation and prevent leakage during transit. |
Competitive 1-Bromo-2,6-Dichloro-4-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Bromo-2,6-Dichloro-4-Fluorobenzene in China?
As a trusted 1-Bromo-2,6-Dichloro-4-Fluorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Bromo-2,6-Dichloro-4-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1-bromo-2,6-dichloro-4-fluorobenzene?
Mercury, commonly known as mercury, also had many uses in ancient times. Its main uses are as follows:
First, it is used in alchemy. In ancient times, alchemy was popular, and scholars believed that mercury had magical effects. Through complex refining processes, they hoped to refine elixirs that could make people immortal. For example, there are records about the use of mercury in alchemy in Ge Hong's "Baopuzi". The scholars believed that after special treatment, mercury could be integrated into medicinal pills to help people prolong life. Although this seems to lack scientific basis today, it was regarded as an important way to pursue longevity at that time.
Second, it is used in medical treatment. Some physicians in ancient times believed that mercury and its compounds had certain medicinal value. For example, mercury ointment is mentioned in some books as being used to treat skin diseases such as scabies. However, due to the strong toxicity of mercury, improper use can easily lead to poisoning, so the application in medical treatment is relatively cautious.
Third, it is used in the gilding process. This is a process in which an alloy of gold and mercury is applied to the surface of metal utensils, and then heated to evaporate the mercury, so that the gold firmly adheres to the surface of the utensils. In ancient times, many exquisite bronzes, gold and silver utensils were decorated by this process to enhance their aesthetics and corrosion resistance. Like some bronze mirrors in ancient times, the gilding decoration on the surface may have used the gilding technology involved in mercury.
Fourth, it is used in tombs. The ancients valued the antiseptic properties of mercury, and in large-scale tombs, especially in imperial tombs, mercury would be used to create a special environment in the hope of better preserving the tomb owner's body and funeral objects. The most typical is Qin Shi Huang's Mausoleum. According to the records of the "Historical Records", "mercury was used to instill the rivers and seas in the rivers and seas." A large amount of mercury in the mausoleum created the image of rivers, lakes and seas, which not only showed the majesty of the emperor and the grand vision of the afterlife world, but also prevented the invasion of tomb robbers and played a certain role in protecting the tomb.
First, it is used in alchemy. In ancient times, alchemy was popular, and scholars believed that mercury had magical effects. Through complex refining processes, they hoped to refine elixirs that could make people immortal. For example, there are records about the use of mercury in alchemy in Ge Hong's "Baopuzi". The scholars believed that after special treatment, mercury could be integrated into medicinal pills to help people prolong life. Although this seems to lack scientific basis today, it was regarded as an important way to pursue longevity at that time.
Second, it is used in medical treatment. Some physicians in ancient times believed that mercury and its compounds had certain medicinal value. For example, mercury ointment is mentioned in some books as being used to treat skin diseases such as scabies. However, due to the strong toxicity of mercury, improper use can easily lead to poisoning, so the application in medical treatment is relatively cautious.
Third, it is used in the gilding process. This is a process in which an alloy of gold and mercury is applied to the surface of metal utensils, and then heated to evaporate the mercury, so that the gold firmly adheres to the surface of the utensils. In ancient times, many exquisite bronzes, gold and silver utensils were decorated by this process to enhance their aesthetics and corrosion resistance. Like some bronze mirrors in ancient times, the gilding decoration on the surface may have used the gilding technology involved in mercury.
Fourth, it is used in tombs. The ancients valued the antiseptic properties of mercury, and in large-scale tombs, especially in imperial tombs, mercury would be used to create a special environment in the hope of better preserving the tomb owner's body and funeral objects. The most typical is Qin Shi Huang's Mausoleum. According to the records of the "Historical Records", "mercury was used to instill the rivers and seas in the rivers and seas." A large amount of mercury in the mausoleum created the image of rivers, lakes and seas, which not only showed the majesty of the emperor and the grand vision of the afterlife world, but also prevented the invasion of tomb robbers and played a certain role in protecting the tomb.
What are the physical properties of 1-bromo-2,6-dichloro-4-fluorobenzene
Mercury, also known as mercury, is a liquid metal at room temperature and is the only metal element that is liquid at room temperature and pressure. It has the following physical properties:
1. ** Color **: Mercury exhibits a silver-white and bright metallic luster, like flowing silver, shining with a unique light under the illumination of light. Although mercury color is not described in detail in "Tiangong Kaiwu", metallic luster is a common metal characteristic, and mercury also has it.
2. ** State **: Under normal conditions, mercury is a liquid, which is its significant characteristic. When the surrounding materials are mostly solid or gaseous, mercury exists in a unique liquid state and can flow freely, just like a smart liquid pearl. " Tiangong Kaiwu mentions that mercury "takes the shape of mercury and changes its quality", indicating that mercury has special liquid properties.
3. ** Density **: Mercury has a high density of 13.59 grams per cubic centimeter, which is much denser than common metals such as iron and copper. When an object is placed in mercury, if the density of the object is less than that of mercury, it will float on the surface of mercury. This phenomenon is not recorded in Tiangong Kaiwu, but it is an important physical property of mercury.
4. ** Melting Point and Boiling Point **: The melting point of mercury is extremely low, -38.87 ° C, which means that it can still remain liquid in cold environments. The boiling point is 356.6 ° C, which is not high compared to some high-boiling metals. Proper heating can easily vaporize it. " "Tiangong Kaiwu" records that the temperature needs to be controlled when refining mercury, which is related to the melting point and boiling point characteristics of mercury.
5. ** Fluidity **: Mercury has excellent fluidity. Because of its liquid state and low cohesion, it will quickly spread out into small droplets on a smooth plane. These small droplets can also fuse with each other, as described in the book. Mercury flows like a "bead".
6. ** Solubility **: Mercury has very little solubility in water, is almost insoluble in water, and can form amalgam with some metals, that is, amalgam. "Tiangong Kaiwu" mentions the use of mercury to extract gold and silver, which is the characteristic of using it to form amalgam with gold and silver.
1. ** Color **: Mercury exhibits a silver-white and bright metallic luster, like flowing silver, shining with a unique light under the illumination of light. Although mercury color is not described in detail in "Tiangong Kaiwu", metallic luster is a common metal characteristic, and mercury also has it.
2. ** State **: Under normal conditions, mercury is a liquid, which is its significant characteristic. When the surrounding materials are mostly solid or gaseous, mercury exists in a unique liquid state and can flow freely, just like a smart liquid pearl. " Tiangong Kaiwu mentions that mercury "takes the shape of mercury and changes its quality", indicating that mercury has special liquid properties.
3. ** Density **: Mercury has a high density of 13.59 grams per cubic centimeter, which is much denser than common metals such as iron and copper. When an object is placed in mercury, if the density of the object is less than that of mercury, it will float on the surface of mercury. This phenomenon is not recorded in Tiangong Kaiwu, but it is an important physical property of mercury.
4. ** Melting Point and Boiling Point **: The melting point of mercury is extremely low, -38.87 ° C, which means that it can still remain liquid in cold environments. The boiling point is 356.6 ° C, which is not high compared to some high-boiling metals. Proper heating can easily vaporize it. " "Tiangong Kaiwu" records that the temperature needs to be controlled when refining mercury, which is related to the melting point and boiling point characteristics of mercury.
5. ** Fluidity **: Mercury has excellent fluidity. Because of its liquid state and low cohesion, it will quickly spread out into small droplets on a smooth plane. These small droplets can also fuse with each other, as described in the book. Mercury flows like a "bead".
6. ** Solubility **: Mercury has very little solubility in water, is almost insoluble in water, and can form amalgam with some metals, that is, amalgam. "Tiangong Kaiwu" mentions the use of mercury to extract gold and silver, which is the characteristic of using it to form amalgam with gold and silver.
What are the synthesis methods of 1-bromo-2,6-dichloro-4-fluorobenzene
To prepare 1-bromo-2,6-difluoro-4-ethylbenzene, there are many methods, which are described in detail below.
First, it can be started by a benzene ring compound containing the corresponding substituent. The bromine atom is introduced at a specific position before the benzene ring, and this step can be achieved by a bromination reaction. If a suitable catalyst, such as iron filings or iron tribromide, is used at a suitable temperature and reaction environment, the benzene ring reacts with the bromine elemental substance, so that the bromine atom is selectively attached to the desired position. Subsequently, a fluorine atom is introduced. The method of introducing a fluorine atom is usually a halogen exchange reaction. In the presence of a phase transfer catalyst, a suitable fluorine-containing reagent, such as potassium fluoride, is co-heated with a bromobenzene-containing cyclic compound to replace the bromine atom with a fluorine atom, and then obtain 2,6-difluoro-1-bromobenzene derivatives. Finally, ethyl is introduced. The Grignard reagent reaction can be used to prepare ethyl magnesium halide first, and then react with 2,6-difluoro-1-bromobenzene derivatives in anhydrous ether or tetrahydrofuran to introduce ethyl to complete the synthesis of 1-bromo-2,6-difluoro-4-ethylbenzene.
Second, the synthesis path can also be conceived from another angle. First construct the benzene ring structure containing ethyl group, for example, use phenylethane as the starting material. For the bromination of phenylethane, the bromine atom is also connected to the specific position of the benzene ring with the help of a suitable catalyst. After that, the fluorination reaction is carried out, and the introduction of fluorine atoms is achieved by selecting suitable fluorine substitution reagents and reaction conditions, and the target product 1-bromo-2,6-difluoro-4-ethylbenzene is gradually synthesized.
When synthesizing this compound, attention should be paid to the precise control of the reaction conditions at each step. Factors such as temperature, reaction time, reagent dosage and catalyst type all have a great impact on the reaction process and product purity. During the reaction process, attention should be paid to the avoidance of side reactions, and the yield and purity of the target product should be improved by optimizing the reaction conditions and selecting appropriate solvents.
First, it can be started by a benzene ring compound containing the corresponding substituent. The bromine atom is introduced at a specific position before the benzene ring, and this step can be achieved by a bromination reaction. If a suitable catalyst, such as iron filings or iron tribromide, is used at a suitable temperature and reaction environment, the benzene ring reacts with the bromine elemental substance, so that the bromine atom is selectively attached to the desired position. Subsequently, a fluorine atom is introduced. The method of introducing a fluorine atom is usually a halogen exchange reaction. In the presence of a phase transfer catalyst, a suitable fluorine-containing reagent, such as potassium fluoride, is co-heated with a bromobenzene-containing cyclic compound to replace the bromine atom with a fluorine atom, and then obtain 2,6-difluoro-1-bromobenzene derivatives. Finally, ethyl is introduced. The Grignard reagent reaction can be used to prepare ethyl magnesium halide first, and then react with 2,6-difluoro-1-bromobenzene derivatives in anhydrous ether or tetrahydrofuran to introduce ethyl to complete the synthesis of 1-bromo-2,6-difluoro-4-ethylbenzene.
Second, the synthesis path can also be conceived from another angle. First construct the benzene ring structure containing ethyl group, for example, use phenylethane as the starting material. For the bromination of phenylethane, the bromine atom is also connected to the specific position of the benzene ring with the help of a suitable catalyst. After that, the fluorination reaction is carried out, and the introduction of fluorine atoms is achieved by selecting suitable fluorine substitution reagents and reaction conditions, and the target product 1-bromo-2,6-difluoro-4-ethylbenzene is gradually synthesized.
When synthesizing this compound, attention should be paid to the precise control of the reaction conditions at each step. Factors such as temperature, reaction time, reagent dosage and catalyst type all have a great impact on the reaction process and product purity. During the reaction process, attention should be paid to the avoidance of side reactions, and the yield and purity of the target product should be improved by optimizing the reaction conditions and selecting appropriate solvents.
What are the precautions for storing and transporting 1-bromo-2,6-dichloro-4-fluorobenzene?
Mercury, carbon dioxide, and acetylene need to be stored and transported in a number of key areas to ensure safety.
Mercury is a liquid metal at room temperature, which is volatile and toxic. When storing mercury, the first seal should be placed in a sturdy and well-sealed container to prevent mercury vapor from escaping into the air, causing environmental pollution and personal hazards. And should be stored in a cool, well-ventilated place, protected from heat and direct sunlight. Due to the increase in temperature, the volatilization rate of mercury will increase. In addition, mercury has a corrosive effect on some metals, so the choice of storage container materials is also very critical. Materials such as stainless steel and ceramics that resist mercury corrosion are appropriate. When transporting mercury, be sure to ensure that the packaging is firm, follow the relevant regulations on the transportation of hazardous chemicals, and be equipped with necessary protective and emergency treatment equipment.
Carbon dioxide, although non-toxic, is a suffocating gas. When storing carbon dioxide, the container must be able to withstand the corresponding pressure, because carbon dioxide will form a high pressure state under certain conditions. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources, to prevent the pressure in the container from rising sharply due to temperature changes. During transportation, it is also necessary to ensure the integrity and sealing of the container, and regularly check the pressure status of the transportation equipment to ensure transportation safety.
Acetylene is a flammable and explosive gas. For storing acetylene, a special acetylene gas cylinder is required, and the bottle has a porous filler and acetone to dissolve acetylene and improve safety. Gas cylinders must be placed upright to prevent acetylene leakage caused by acetone outflow. Fireworks should be strictly prohibited in storage places, and good lightning protection, anti-static and fire prevention measures should be taken. When transporting acetylene, vehicles must have obvious dangerous chemical labels, follow specific transportation routes and times, and avoid violent vibrations and collisions during transportation to prevent acetylene explosions.
In short, mercury, carbon dioxide, and acetylene have different points of attention when storing and transporting due to their characteristics. However, strict adherence to safety regulations and protection of personnel and the environment are of paramount importance.
Mercury is a liquid metal at room temperature, which is volatile and toxic. When storing mercury, the first seal should be placed in a sturdy and well-sealed container to prevent mercury vapor from escaping into the air, causing environmental pollution and personal hazards. And should be stored in a cool, well-ventilated place, protected from heat and direct sunlight. Due to the increase in temperature, the volatilization rate of mercury will increase. In addition, mercury has a corrosive effect on some metals, so the choice of storage container materials is also very critical. Materials such as stainless steel and ceramics that resist mercury corrosion are appropriate. When transporting mercury, be sure to ensure that the packaging is firm, follow the relevant regulations on the transportation of hazardous chemicals, and be equipped with necessary protective and emergency treatment equipment.
Carbon dioxide, although non-toxic, is a suffocating gas. When storing carbon dioxide, the container must be able to withstand the corresponding pressure, because carbon dioxide will form a high pressure state under certain conditions. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources, to prevent the pressure in the container from rising sharply due to temperature changes. During transportation, it is also necessary to ensure the integrity and sealing of the container, and regularly check the pressure status of the transportation equipment to ensure transportation safety.
Acetylene is a flammable and explosive gas. For storing acetylene, a special acetylene gas cylinder is required, and the bottle has a porous filler and acetone to dissolve acetylene and improve safety. Gas cylinders must be placed upright to prevent acetylene leakage caused by acetone outflow. Fireworks should be strictly prohibited in storage places, and good lightning protection, anti-static and fire prevention measures should be taken. When transporting acetylene, vehicles must have obvious dangerous chemical labels, follow specific transportation routes and times, and avoid violent vibrations and collisions during transportation to prevent acetylene explosions.
In short, mercury, carbon dioxide, and acetylene have different points of attention when storing and transporting due to their characteristics. However, strict adherence to safety regulations and protection of personnel and the environment are of paramount importance.
What are the effects of 1-bromo-2,6-dichloro-4-fluorobenzene on the environment and human health?
On the Effects of Mercury, Sulfur Dioxide and Mussels on the Environment and Human Health
Mercury is a highly toxic substance. It can be transported and transformed in various ways in the environment. If mercury is released into water bodies, it can be ingested by aquatic organisms, enriched through the food chain, and eventually human body. If people eat organisms containing mercury, mercury accumulates in the body, damaging the nervous system, kidneys, etc. In light cases, it can cause dizziness, fatigue, and insomnia; in severe cases, it can cause tremors in the limbs, mental disorders, and even life-threatening. And mercury evaporates in the atmosphere, and can also return to the ground with precipitation, polluting soil, water sources, and harming all things.
Sulfur dioxide, a common atmospheric pollutant. It comes from the combustion of sulfur-containing fuels. In the environment, sulfur dioxide can form acid rain. Acid rain falls on the earth, erodes soil, acidifies soil, loses nutrients, reduces fertility, and hinders plant growth. And acid rain leaches water bodies, causing acidification of water bodies, endangering the survival of aquatic organisms. In the human body, sulfur dioxide irritates the respiratory tract, causing coughing, asthma and other diseases. Living in an environment containing sulfur dioxide for a long time increases the risk of respiratory diseases and cardiovascular diseases.
Although mussels are aquatic organisms, they also play an important role in the environment. Mussels filter plankton and organic debris in the water, which can purify water bodies and maintain water ecological balance. However, if the environment is polluted, mussels are also harmed. If mercury, sulfur dioxide and other pollutants in the water exceed the standard, mussels are enriched with toxins, which not only threatens their own survival, but also causes health problems if people eat them. And the survival status of mussels can reflect the health of the water body and is an ecological indicator organism.
Therefore, mercury, sulfur dioxide and mussels are harmful or beneficial to the environment and human health. They all need to be treated with care to ensure the safety of the environment and the health of the human body.
Mercury is a highly toxic substance. It can be transported and transformed in various ways in the environment. If mercury is released into water bodies, it can be ingested by aquatic organisms, enriched through the food chain, and eventually human body. If people eat organisms containing mercury, mercury accumulates in the body, damaging the nervous system, kidneys, etc. In light cases, it can cause dizziness, fatigue, and insomnia; in severe cases, it can cause tremors in the limbs, mental disorders, and even life-threatening. And mercury evaporates in the atmosphere, and can also return to the ground with precipitation, polluting soil, water sources, and harming all things.
Sulfur dioxide, a common atmospheric pollutant. It comes from the combustion of sulfur-containing fuels. In the environment, sulfur dioxide can form acid rain. Acid rain falls on the earth, erodes soil, acidifies soil, loses nutrients, reduces fertility, and hinders plant growth. And acid rain leaches water bodies, causing acidification of water bodies, endangering the survival of aquatic organisms. In the human body, sulfur dioxide irritates the respiratory tract, causing coughing, asthma and other diseases. Living in an environment containing sulfur dioxide for a long time increases the risk of respiratory diseases and cardiovascular diseases.
Although mussels are aquatic organisms, they also play an important role in the environment. Mussels filter plankton and organic debris in the water, which can purify water bodies and maintain water ecological balance. However, if the environment is polluted, mussels are also harmed. If mercury, sulfur dioxide and other pollutants in the water exceed the standard, mussels are enriched with toxins, which not only threatens their own survival, but also causes health problems if people eat them. And the survival status of mussels can reflect the health of the water body and is an ecological indicator organism.
Therefore, mercury, sulfur dioxide and mussels are harmful or beneficial to the environment and human health. They all need to be treated with care to ensure the safety of the environment and the health of the human body.
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