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1-Bromo-2-(Bromomethyl)-4-Chlorobenzene
Linshang Chemical
|
HS Code |
580265 |
| Chemical Formula | C7H5Br2Cl |
| Molecular Weight | 286.38 g/mol |
| Appearance | Solid (usually white to off - white) |
| Boiling Point | Estimated around 290 - 300 °C |
| Melting Point | Approximately 70 - 75 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Hazard Class | Irritant, potentially harmful if swallowed, inhaled or in contact with skin |
As an accredited 1-Bromo-2-(Bromomethyl)-4-Chlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 1 - bromo - 2 - (bromomethyl)-4 - chlorobenzene packaged in a sealed chemical bottle. |
| Storage | 1 - bromo - 2 - (bromomethyl)-4 - chlorobenzene should be stored in a cool, dry, well - ventilated area, away from sources of heat and ignition. It should be kept in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents, strong bases, and reactive metals to avoid potential chemical reactions. |
| Shipping | 1 - bromo - 2 - (bromomethyl)-4 - chlorobenzene is shipped in tightly sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring safe transport to prevent any spill or environmental hazard. |
Competitive 1-Bromo-2-(Bromomethyl)-4-Chlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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As a leading 1-Bromo-2-(Bromomethyl)-4-Chlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the Chinese name of 1 - bromo - 2 - (bromomethyl) - 4 - chlorobenzene?
1-Bromo-2- (bromomethyl) -4-chlorobenzene is one of the organic compounds. Its naming follows chemical naming rules. The core structure of this compound is a benzene ring, which is connected with bromine atoms, bromomethyl and chlorine atoms.
Looking at the name of this compound, "1-bromo" means that there is a bromine atom at the 1st position of the benzene ring; "2- (bromomethyl) " means that there is a bromomethyl at the 2nd position of the benzene ring, and this bromomethyl group is a -CH-Br group; "4-chlorine" means that there is a chlorine atom at the 4th position of the benzene ring. In this way, the name is derived from the position and type of the substituent on the benzene ring.
The naming of organic compounds is designed to accurately describe their structures and enable chemists to communicate clearly. The name 1-bromo-2- (bromomethyl) -4-chlorobenzene is based on the rules set by the International Union of Pure and Applied Chemistry (IUPAC). In the field of chemistry, everyone names compounds according to this rule to ensure uniformity and accuracy of names, avoid confusion, and facilitate chemical research and communication.
Looking at the name of this compound, "1-bromo" means that there is a bromine atom at the 1st position of the benzene ring; "2- (bromomethyl) " means that there is a bromomethyl at the 2nd position of the benzene ring, and this bromomethyl group is a -CH-Br group; "4-chlorine" means that there is a chlorine atom at the 4th position of the benzene ring. In this way, the name is derived from the position and type of the substituent on the benzene ring.
The naming of organic compounds is designed to accurately describe their structures and enable chemists to communicate clearly. The name 1-bromo-2- (bromomethyl) -4-chlorobenzene is based on the rules set by the International Union of Pure and Applied Chemistry (IUPAC). In the field of chemistry, everyone names compounds according to this rule to ensure uniformity and accuracy of names, avoid confusion, and facilitate chemical research and communication.
What are the main uses of 1 - bromo - 2 - (bromomethyl) - 4 - chlorobenzene?
1 + -Bromo-2- (bromomethyl) -4 -chlorobenzene is also an organic compound. It has a wide range of uses and is often a key intermediate in the field of organic synthesis.
First, it can be used to create new pesticides. After ingenious chemical reaction, it is introduced into a specific structure, which can produce pesticides with high insecticidal and bactericidal properties. Because of its special structure, it can accurately act on specific targets of pests and pathogens, enhance drug efficacy, and reduce the adverse impact on the environment, so it is important for the research and development of modern pesticides.
Second, it also plays an important role in the field of pharmaceutical synthesis. It can be used as a starting material to construct compounds containing special functional groups through a series of complex reactions, and then develop new drug molecules. For example, in the research and development of anti-tumor and antibacterial drugs, the unique structure of 1 + -bromo-2- (bromomethyl) -4 -chlorobenzene may provide a key help for the improvement of drug activity and specificity.
Third, in the field of materials science, it can participate in the synthesis of polymer materials. By polymerizing with other monomers, polymer materials are endowed with unique properties, such as improving the heat resistance and chemical corrosion resistance of materials. For example, in the preparation of special engineering plastics, after its participation in the reaction, or under high temperature and chemical corrosion environment, the plastic can still maintain good physical and chemical properties and broaden the application range of materials. Therefore, 1 + -bromo-2- (bromomethyl) -4 -chlorobenzene plays an important role in many fields of chemical industry, promoting the progress and development of pesticide, medicine, materials and other industries.
First, it can be used to create new pesticides. After ingenious chemical reaction, it is introduced into a specific structure, which can produce pesticides with high insecticidal and bactericidal properties. Because of its special structure, it can accurately act on specific targets of pests and pathogens, enhance drug efficacy, and reduce the adverse impact on the environment, so it is important for the research and development of modern pesticides.
Second, it also plays an important role in the field of pharmaceutical synthesis. It can be used as a starting material to construct compounds containing special functional groups through a series of complex reactions, and then develop new drug molecules. For example, in the research and development of anti-tumor and antibacterial drugs, the unique structure of 1 + -bromo-2- (bromomethyl) -4 -chlorobenzene may provide a key help for the improvement of drug activity and specificity.
Third, in the field of materials science, it can participate in the synthesis of polymer materials. By polymerizing with other monomers, polymer materials are endowed with unique properties, such as improving the heat resistance and chemical corrosion resistance of materials. For example, in the preparation of special engineering plastics, after its participation in the reaction, or under high temperature and chemical corrosion environment, the plastic can still maintain good physical and chemical properties and broaden the application range of materials. Therefore, 1 + -bromo-2- (bromomethyl) -4 -chlorobenzene plays an important role in many fields of chemical industry, promoting the progress and development of pesticide, medicine, materials and other industries.
What are the physical properties of 1 - bromo - 2 - (bromomethyl) - 4 - chlorobenzene?
1 + -Bromo-2- (bromomethyl) -4 -chlorobenzene is also an organic compound. Its physical properties are as follows:
Under normal temperature, this is a colorless to light yellow liquid or solid, depending on the specific environmental conditions. Smell, there is a special smell, but its taste is not strong and pungent, relatively mild.
On its melting point, it is about a specific temperature range, and the specific value will vary slightly depending on the amount of impurities contained and the accuracy of the measurement. Generally speaking, the value of the melting point helps to identify this compound, and it is an important reference in the process of separation and purification of substances.
Boiling point is also a key physical property. Under specific pressure conditions, its boiling temperature has a certain range. The determination of boiling point is related to the implementation of separation methods such as distillation and fractionation of substances in chemical production and laboratory operations.
In terms of density, it has a certain value relative to water. This property determines its distribution when mixed with other liquids such as water, and is of great significance in extraction, phase separation and other operations.
Solubility is quite important. 1 + -Bromo-2- (bromomethyl) -4 -chlorobenzene has good solubility in organic solvents such as ethanol, ether, dichloromethane, etc. It can be miscible or partially miscible with these organic solvents. However, in water, its solubility is poor and it is difficult to dissolve in water. This solubility characteristic plays an important guiding role in chemical synthesis, product separation, reaction medium selection, and many other aspects.
In addition, its volatility is relatively moderate, and non-volatile substances can maintain a relatively stable state in general storage and use environments. However, appropriate storage conditions are also required to prevent volatilization loss or cause safety problems. These physical properties are indispensable information in chemical research, industrial production and related application fields to help researchers and producers make good use of this compound.
Under normal temperature, this is a colorless to light yellow liquid or solid, depending on the specific environmental conditions. Smell, there is a special smell, but its taste is not strong and pungent, relatively mild.
On its melting point, it is about a specific temperature range, and the specific value will vary slightly depending on the amount of impurities contained and the accuracy of the measurement. Generally speaking, the value of the melting point helps to identify this compound, and it is an important reference in the process of separation and purification of substances.
Boiling point is also a key physical property. Under specific pressure conditions, its boiling temperature has a certain range. The determination of boiling point is related to the implementation of separation methods such as distillation and fractionation of substances in chemical production and laboratory operations.
In terms of density, it has a certain value relative to water. This property determines its distribution when mixed with other liquids such as water, and is of great significance in extraction, phase separation and other operations.
Solubility is quite important. 1 + -Bromo-2- (bromomethyl) -4 -chlorobenzene has good solubility in organic solvents such as ethanol, ether, dichloromethane, etc. It can be miscible or partially miscible with these organic solvents. However, in water, its solubility is poor and it is difficult to dissolve in water. This solubility characteristic plays an important guiding role in chemical synthesis, product separation, reaction medium selection, and many other aspects.
In addition, its volatility is relatively moderate, and non-volatile substances can maintain a relatively stable state in general storage and use environments. However, appropriate storage conditions are also required to prevent volatilization loss or cause safety problems. These physical properties are indispensable information in chemical research, industrial production and related application fields to help researchers and producers make good use of this compound.
What are the synthesis methods of 1 - bromo - 2 - (bromomethyl) - 4 - chlorobenzene?
1 + -Bromo-2- (bromomethyl) -4 -chlorobenzene is also an organic compound. The synthesis method has the following numbers:
First, 4-chlorotoluene is used as the starting material. Shilling 4-chlorotoluene reacts with bromine under the condition of light, which is a free radical substitution reaction. Bromine atoms selectively replace hydrogen atoms in the benzyl position to obtain 4-chlorobenzyl bromide. Then, 4-chlorobenzyl bromide is reacted with N-bromosuccinimide (NBS) in the presence of an initiator. NBS can provide bromine radicals, and the radical substitution reaction occurs again. Bromo-methyl is introduced at the ortho-position of benzyl, and then 1 + -bromo-2- (bromomethyl) -4 -chlorobenzene is obtained. This approach is relatively simple, and the raw material 4-chlorotoluene is quite common and easy to obtain.
Second, 2-methyl-5-chloroaniline is used as the starting material. It is first diazotized, treated with sodium nitrite and hydrochloric acid to obtain diazonium salt. Then, the diazonium salt is reacted with cuprous bromide, and the Sandmeyer reaction occurs. The diazonium group is replaced by the bromine atom to obtain 2-bromo-5-chlorotoluene. After that, 2-bromo-5-chlorotoluene is brominated with bromine under appropriate conditions, and the benzyl position is introduced into bromomethyl to obtain the target product 1 + -bromo-2- (bromomethyl) -4-chlorobenzene. Although this method has a little more steps, it has high selectivity and can effectively obtain the desired product.
Third, 2-methyl-5-chlorobenzoic acid is used as the starting material. First, it is reduced to 2-methyl-5-chlorobenzyl alcohol, which can be achieved by reducing agents such as lithium aluminum hydride. Then, 2-methyl-5-chlorobenzyl alcohol reacts with phosphorus tribromide, and the hydroxyl group is replaced by a bromine atom to obtain 2-bromomethyl-5-chlorotoluene. Finally, bromine atoms are introduced into the ortho-position of the benzene ring under the action of bromine under light or initiator to obtain 1 + -bromo-2- (bromomethyl) -4-chlorobenzene. This path can also successfully synthesize the target compound, and the reaction conditions at each step are relatively mild and easy to control.
First, 4-chlorotoluene is used as the starting material. Shilling 4-chlorotoluene reacts with bromine under the condition of light, which is a free radical substitution reaction. Bromine atoms selectively replace hydrogen atoms in the benzyl position to obtain 4-chlorobenzyl bromide. Then, 4-chlorobenzyl bromide is reacted with N-bromosuccinimide (NBS) in the presence of an initiator. NBS can provide bromine radicals, and the radical substitution reaction occurs again. Bromo-methyl is introduced at the ortho-position of benzyl, and then 1 + -bromo-2- (bromomethyl) -4 -chlorobenzene is obtained. This approach is relatively simple, and the raw material 4-chlorotoluene is quite common and easy to obtain.
Second, 2-methyl-5-chloroaniline is used as the starting material. It is first diazotized, treated with sodium nitrite and hydrochloric acid to obtain diazonium salt. Then, the diazonium salt is reacted with cuprous bromide, and the Sandmeyer reaction occurs. The diazonium group is replaced by the bromine atom to obtain 2-bromo-5-chlorotoluene. After that, 2-bromo-5-chlorotoluene is brominated with bromine under appropriate conditions, and the benzyl position is introduced into bromomethyl to obtain the target product 1 + -bromo-2- (bromomethyl) -4-chlorobenzene. Although this method has a little more steps, it has high selectivity and can effectively obtain the desired product.
Third, 2-methyl-5-chlorobenzoic acid is used as the starting material. First, it is reduced to 2-methyl-5-chlorobenzyl alcohol, which can be achieved by reducing agents such as lithium aluminum hydride. Then, 2-methyl-5-chlorobenzyl alcohol reacts with phosphorus tribromide, and the hydroxyl group is replaced by a bromine atom to obtain 2-bromomethyl-5-chlorotoluene. Finally, bromine atoms are introduced into the ortho-position of the benzene ring under the action of bromine under light or initiator to obtain 1 + -bromo-2- (bromomethyl) -4-chlorobenzene. This path can also successfully synthesize the target compound, and the reaction conditions at each step are relatively mild and easy to control.
1 - bromo - 2 - (bromomethyl) - 4 - chlorobenzene What are the precautions during storage and transportation?
1+-+bromo+-+2+-+%28bromomethyl%29+-+4+-+chlorobenzene is 1-bromo-2- (bromomethyl) -4-chlorobenzene. When storing and transporting this substance, many matters need to be paid attention to.
First storage environment. This substance should be stored in a cool, dry and well-ventilated place. Because it is more sensitive to heat, high temperature is easy to decompose or cause other chemical reactions, so it must be kept away from heat sources and fire sources. High temperature areas such as boiler rooms and heating equipment must not be placed. Air humidity is also affected. Humid air may cause reactions such as hydrolysis, so the humidity of the warehouse should be strictly controlled, usually 40% -60% relative humidity.
Furthermore, it is related to packaging. Packaging must be tight to prevent leakage. Commonly used sealed containers, such as glass bottles need to be sealed with frosted glass plugs to ensure that no air and moisture penetrate; if plastic containers are used, the material should be resistant to corrosion of bromine and chlorine-related compounds. Warning signs should be clearly marked on the outside of the package, such as toxic, harmful, corrosive, etc., so that contacts can see at a glance and avoid accidents.
When transporting, choose suitable transportation tools. Because of its certain danger, professional chemicals need to be used to transport vehicles. Vehicles should be equipped with perfect fire protection equipment and leakage emergency treatment tools. During transportation, be sure to drive smoothly to avoid bumps, vibrations and collisions to prevent packaging damage. At the same time, transportation routes should avoid sensitive areas such as densely populated areas and water source reserves to reduce the risk of accidents.
In addition, operators must be professionally trained and familiar with the characteristics, hazards and emergency treatment methods of the substance. Storage and transportation sites should develop detailed emergency plans. In the event of leaks and other accidents, they can respond quickly and effectively to ensure the safety of personnel and the environment.
First storage environment. This substance should be stored in a cool, dry and well-ventilated place. Because it is more sensitive to heat, high temperature is easy to decompose or cause other chemical reactions, so it must be kept away from heat sources and fire sources. High temperature areas such as boiler rooms and heating equipment must not be placed. Air humidity is also affected. Humid air may cause reactions such as hydrolysis, so the humidity of the warehouse should be strictly controlled, usually 40% -60% relative humidity.
Furthermore, it is related to packaging. Packaging must be tight to prevent leakage. Commonly used sealed containers, such as glass bottles need to be sealed with frosted glass plugs to ensure that no air and moisture penetrate; if plastic containers are used, the material should be resistant to corrosion of bromine and chlorine-related compounds. Warning signs should be clearly marked on the outside of the package, such as toxic, harmful, corrosive, etc., so that contacts can see at a glance and avoid accidents.
When transporting, choose suitable transportation tools. Because of its certain danger, professional chemicals need to be used to transport vehicles. Vehicles should be equipped with perfect fire protection equipment and leakage emergency treatment tools. During transportation, be sure to drive smoothly to avoid bumps, vibrations and collisions to prevent packaging damage. At the same time, transportation routes should avoid sensitive areas such as densely populated areas and water source reserves to reduce the risk of accidents.
In addition, operators must be professionally trained and familiar with the characteristics, hazards and emergency treatment methods of the substance. Storage and transportation sites should develop detailed emergency plans. In the event of leaks and other accidents, they can respond quickly and effectively to ensure the safety of personnel and the environment.
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