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1-Bromo-2-Chloro-3-(Trifluoromethyl)Benzene
Linshang Chemical
|
HS Code |
693016 |
| Chemical Formula | C7H3BrClF3 |
| Molecular Weight | 275.45 |
| Appearance | Liquid (predicted, based on similar compounds) |
| Boiling Point | Estimated around 190 - 210 °C (predicted, based on related halogenated aromatic compounds) |
| Density | Estimated around 1.8 - 2.0 g/cm³ (predicted, based on similar halogen - containing aromatic compounds) |
| Solubility In Water | Insoluble (due to non - polar nature of the aromatic ring and hydrophobic halogen and trifluoromethyl groups) |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform, toluene (similar to other halogenated aromatic hydrocarbons) |
| Vapor Pressure | Low vapor pressure at room temperature (predicted, due to relatively high molecular weight and non - volatile nature of the molecule) |
As an accredited 1-Bromo-2-Chloro-3-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - bromo - 2 - chloro - 3 - (trifluoromethyl)benzene in 500 mL glass bottle, tightly sealed. |
| Storage | 1 - Bromo - 2 - chloro - 3 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reducing agents, and reactive chemicals to prevent potential reactions. |
| Shipping | 1 - bromo - 2 - chloro - 3 - (trifluoromethyl)benzene is a chemical. It should be shipped in properly labeled, sealed containers, following hazardous material regulations, ensuring secure transportation to prevent spills and environmental or safety risks. |
Competitive 1-Bromo-2-Chloro-3-(Trifluoromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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What are the main uses of 1-bromo-2-chloro-3- (trifluoromethyl) benzene?
What is the main use of 1 + -mercury-2-arsenic-3- (triethylmethyl) germanium?
Mercury is used in ancient times. Alchemists want to be born, and they combine mercury and other substances to obtain immortality. It is also used as a material for some special utensils. Due to the characteristics of mercury, the utensils can have anti-toxic and beautiful effects. However, the world knows that mercury is toxic and harmful to human health, so there are many restrictions on the use of mercury today.
Arsenic was occasionally used in the past. In ancient times, due to its trace toxicity, it was used to treat some diseases, such as scabies and other skin diseases. However, the dosage was controlled, and the poisoning caused by a little carelessness was caused. It is also used as one of the most important factors to remove damage to fields and ensure the safety of crops. However, the toxicity of arsenic is strong, and it is easy to remain in the environment and crops, as well as humans and animals, so it has been used less today.
(triethyl methyl) germanium, which has not been used in ancient literature, has not been synthesized because of the lack of scientific technology. However, today, (triethyl) germanium and its derivatives are not being injected in the research field, and may have anti-cancer and other effects. However, it is still in the research stage and has not been widely used in beds.
Mercury is used in ancient times. Alchemists want to be born, and they combine mercury and other substances to obtain immortality. It is also used as a material for some special utensils. Due to the characteristics of mercury, the utensils can have anti-toxic and beautiful effects. However, the world knows that mercury is toxic and harmful to human health, so there are many restrictions on the use of mercury today.
Arsenic was occasionally used in the past. In ancient times, due to its trace toxicity, it was used to treat some diseases, such as scabies and other skin diseases. However, the dosage was controlled, and the poisoning caused by a little carelessness was caused. It is also used as one of the most important factors to remove damage to fields and ensure the safety of crops. However, the toxicity of arsenic is strong, and it is easy to remain in the environment and crops, as well as humans and animals, so it has been used less today.
(triethyl methyl) germanium, which has not been used in ancient literature, has not been synthesized because of the lack of scientific technology. However, today, (triethyl) germanium and its derivatives are not being injected in the research field, and may have anti-cancer and other effects. However, it is still in the research stage and has not been widely used in beds.
What are the physical properties of 1-bromo-2-chloro-3- (trifluoromethyl) benzene?
1 + - - 2 - 🥰 - 3 - (triethylmethyl) germanium is an organic compound, and its physical properties are as follows:
This compound is mostly liquid at room temperature and pressure. Due to its moderate intermolecular force, it is not enough to solidify it into a solid state, but it can maintain a certain volume and is different from the gaseous state. Looking at its appearance, the pure one is clear and transparent, like crystal clear water, with no impurities mixed in it, highlighting its pure texture.
Smell it, it has a special smell, the smell is not pungent and unpleasant, nor is it fragrant and pleasant. It is a unique smell of organic matter, which can be often smelled in the laboratory, and familiar people will know its uniqueness when they smell it.
Its density is slightly smaller than that of water. If it drops on the water surface, this substance will slowly float on the water, like a light boat floating on a blue wave. This is determined by its molecular structure, resulting in its unit volume mass being smaller than that of water.
When it comes to solubility, it can be soluble in many organic solvents, such as ethanol, ether, etc., just like fish entering water. This is due to the principle of similar phase dissolution. Its organic structure and organic solvent molecules can form a weak force, so it is soluble. However, in water, its solubility is extremely poor, and the two seem to be distinct and difficult to blend. Because of the force between water molecules, it is difficult to overcome the hydrogen bond between water molecules.
In terms of thermal stability, within a certain temperature range, its structure is stable and it is not easy to decompose. However, if the temperature is too high, the chemical bonds in the molecule will be excited and start to break and rearrange, triggering decomposition reactions, resulting in changes in its chemical properties.
The boiling point of this compound is within a specific range according to its intermolecular force and molecular weight. When heated, when it reaches this boiling point, it changes from liquid to gaseous state, and the molecules break free from each other and float freely in space.
This compound is mostly liquid at room temperature and pressure. Due to its moderate intermolecular force, it is not enough to solidify it into a solid state, but it can maintain a certain volume and is different from the gaseous state. Looking at its appearance, the pure one is clear and transparent, like crystal clear water, with no impurities mixed in it, highlighting its pure texture.
Smell it, it has a special smell, the smell is not pungent and unpleasant, nor is it fragrant and pleasant. It is a unique smell of organic matter, which can be often smelled in the laboratory, and familiar people will know its uniqueness when they smell it.
Its density is slightly smaller than that of water. If it drops on the water surface, this substance will slowly float on the water, like a light boat floating on a blue wave. This is determined by its molecular structure, resulting in its unit volume mass being smaller than that of water.
When it comes to solubility, it can be soluble in many organic solvents, such as ethanol, ether, etc., just like fish entering water. This is due to the principle of similar phase dissolution. Its organic structure and organic solvent molecules can form a weak force, so it is soluble. However, in water, its solubility is extremely poor, and the two seem to be distinct and difficult to blend. Because of the force between water molecules, it is difficult to overcome the hydrogen bond between water molecules.
In terms of thermal stability, within a certain temperature range, its structure is stable and it is not easy to decompose. However, if the temperature is too high, the chemical bonds in the molecule will be excited and start to break and rearrange, triggering decomposition reactions, resulting in changes in its chemical properties.
The boiling point of this compound is within a specific range according to its intermolecular force and molecular weight. When heated, when it reaches this boiling point, it changes from liquid to gaseous state, and the molecules break free from each other and float freely in space.
What are the chemical properties of 1-bromo-2-chloro-3- (trifluoromethyl) benzene?
What are the chemical properties of 1 + -alcohol-2-aldehyde-3- (triethylmethyl) benzene? This is a question about the properties of compounds in organic chemistry. To understand its properties, it is necessary to look at both the structure and the reaction.
Preface structure. The compound contains a benzene ring substituted with alcoholic hydroxyl groups, aldehyde groups and triethylmethyl groups. Among the alcoholic hydroxyl groups, the oxygen atom is highly electronegative, the hydrogen-oxygen bond polarity is large, and hydrogen has certain activity. Substitution reactions can occur, such as reacting with hydrogen halides to form halogenated hydrocarbons, which can also be dehydrated to alkenes or ethers. In the aldehyde group, the carbon-oxygen double bond is an unsaturated structure, which has high reactivity and can undergo addition reactions, such as addition to hydrogen to form alcohols; and the aldehyde group can be oxidized, and weak oxidants such as Torun reagent and Feilin reagent can oxidize it to carboxyl groups. Although the benzene ring is highly unsaturated, it is generally difficult to add and easy to replace due to the stability of the conjugate system. The presence of triethyl methyl affects the electron cloud distribution of the benzene ring, resulting in different selectivity of the substitution reaction region on the benzene ring.
Look at the reaction characteristics again. From the perspective of oxidation, alcohol hydroxyl groups can be oxidized, and depending on the conditions and the oxidizing agent used, they can be oxidized to aldehyde or carboxylic acid; aldehyde groups are also easily oxidized and In terms of the substitution reaction, the alcohol hydroxyl group can be replaced by the nucleophilic reagent, and the benzene ring can undergo electrophilic substitution. Because triethyl is the donator group, the electron cloud density of the benzene ring increases, and the electrophilic substitution is more likely to occur in the ortho-para-position. In addition reactions, the aldehyde-carbon-oxygen double bond can be added to compounds containing active hydrogen, such as with alcohol to form acetals.
In summary, the functional groups contained in 1 + -alcohol-2-aldehyde-3- (triethylmethyl) benzene interact with the benzene ring, showing rich and diverse chemical properties, which are of great significance and potential application value in organic synthesis and other fields.
Preface structure. The compound contains a benzene ring substituted with alcoholic hydroxyl groups, aldehyde groups and triethylmethyl groups. Among the alcoholic hydroxyl groups, the oxygen atom is highly electronegative, the hydrogen-oxygen bond polarity is large, and hydrogen has certain activity. Substitution reactions can occur, such as reacting with hydrogen halides to form halogenated hydrocarbons, which can also be dehydrated to alkenes or ethers. In the aldehyde group, the carbon-oxygen double bond is an unsaturated structure, which has high reactivity and can undergo addition reactions, such as addition to hydrogen to form alcohols; and the aldehyde group can be oxidized, and weak oxidants such as Torun reagent and Feilin reagent can oxidize it to carboxyl groups. Although the benzene ring is highly unsaturated, it is generally difficult to add and easy to replace due to the stability of the conjugate system. The presence of triethyl methyl affects the electron cloud distribution of the benzene ring, resulting in different selectivity of the substitution reaction region on the benzene ring.
Look at the reaction characteristics again. From the perspective of oxidation, alcohol hydroxyl groups can be oxidized, and depending on the conditions and the oxidizing agent used, they can be oxidized to aldehyde or carboxylic acid; aldehyde groups are also easily oxidized and In terms of the substitution reaction, the alcohol hydroxyl group can be replaced by the nucleophilic reagent, and the benzene ring can undergo electrophilic substitution. Because triethyl is the donator group, the electron cloud density of the benzene ring increases, and the electrophilic substitution is more likely to occur in the ortho-para-position. In addition reactions, the aldehyde-carbon-oxygen double bond can be added to compounds containing active hydrogen, such as with alcohol to form acetals.
In summary, the functional groups contained in 1 + -alcohol-2-aldehyde-3- (triethylmethyl) benzene interact with the benzene ring, showing rich and diverse chemical properties, which are of great significance and potential application value in organic synthesis and other fields.
What are the methods for synthesizing 1-bromo-2-chloro-3- (trifluoromethyl) benzene?
To prepare 1-bromo-2-chloro-3- (trifluoromethyl) benzene, the following ancient methods can be used.
First, benzene is used as the starting material. Under the catalysis of iron bromide, benzene and bromine undergo an electrophilic substitution reaction to obtain bromobenzene. The main purpose of this reaction is to activate the bromine molecule in the iron bromide, so that the positive ion of bromine is generated, which then attacks the benzene ring and forms the product of bromobenzene. The reaction formula is:\ (C_ {6} H_ {6} + Br_ {2}\ stackrel {FeBr_ {3}} {\ longrightarrow} C_ {6} H_ {5} Br + HBr\).
After obtaining bromobenzene, bromobenzene and chlorine are introduced into the ortho-position of the benzene ring under the action of light or a specific catalyst. The key to this step is the precise control of the reaction conditions. Light initiates chlorine radicals and realizes ortho-substitution to obtain 1-bromo-2-chlorobenzene. The reaction is roughly as follows:\ (C_ {6} H_ {5} Br + Cl_ {2}\ stackrel {light or catalyst} {\ longrightarrow} C_ {6} H_ {4} BrCl + HCl\).
Finally, 1-bromo-2-chlorobenzene is combined with a trifluoromethylation reagent, such as trifluoromethyl halide (\ (CF_ {3} MgX\)), in a suitable solvent such as anhydrous ether, according to the mechanism of Grignard reaction, trifluoromethyl is introduced to obtain 1-bromo-2-chloro-3- (trifluoromethyl) benzene. This step requires an anhydrous and anaerobic environment to achieve the activity of Bogle's reagent. The reaction is as follows:\ (C_ {6} H_ {4} BrCl + CF_ {3} MgX\ stackrel {anhydrous ether} {\ longrightarrow} C_ {6} H_ {3} BrCl (CF_ {3}) + MgBrX\).
Second, chlorobenzene can also be used as the starting material. First, under the action of a suitable catalyst, chlorobenzene and bromine are introduced into the ortho-position of chlorobenzene through electrophilic substitution to obtain 1-chloro-2-bromobenzene. This catalyst can assist in the polarization of bromine molecules and promote the reaction. The reaction formula is:\ (C_ {6} H_ {5} Cl + Br_ {2}\ stackrel {catalyst} {\ longrightarrow} C_ {6} H_ {4} ClBr + HBr\).
Then, 1-chloro-2-bromobenzene reacts with a trifluoromethylating reagent to introduce trifluoromethyl. This reaction process requires attention to the dosage and reaction conditions of trifluoromethylating reagents to obtain the target product 1-bromo-2-chloro-3- (trifluoromethyl) benzene in high yields. This process is similar to the Grignard reaction principle, and the introduction of groups is achieved by means of interreagent activity.
First, benzene is used as the starting material. Under the catalysis of iron bromide, benzene and bromine undergo an electrophilic substitution reaction to obtain bromobenzene. The main purpose of this reaction is to activate the bromine molecule in the iron bromide, so that the positive ion of bromine is generated, which then attacks the benzene ring and forms the product of bromobenzene. The reaction formula is:\ (C_ {6} H_ {6} + Br_ {2}\ stackrel {FeBr_ {3}} {\ longrightarrow} C_ {6} H_ {5} Br + HBr\).
After obtaining bromobenzene, bromobenzene and chlorine are introduced into the ortho-position of the benzene ring under the action of light or a specific catalyst. The key to this step is the precise control of the reaction conditions. Light initiates chlorine radicals and realizes ortho-substitution to obtain 1-bromo-2-chlorobenzene. The reaction is roughly as follows:\ (C_ {6} H_ {5} Br + Cl_ {2}\ stackrel {light or catalyst} {\ longrightarrow} C_ {6} H_ {4} BrCl + HCl\).
Finally, 1-bromo-2-chlorobenzene is combined with a trifluoromethylation reagent, such as trifluoromethyl halide (\ (CF_ {3} MgX\)), in a suitable solvent such as anhydrous ether, according to the mechanism of Grignard reaction, trifluoromethyl is introduced to obtain 1-bromo-2-chloro-3- (trifluoromethyl) benzene. This step requires an anhydrous and anaerobic environment to achieve the activity of Bogle's reagent. The reaction is as follows:\ (C_ {6} H_ {4} BrCl + CF_ {3} MgX\ stackrel {anhydrous ether} {\ longrightarrow} C_ {6} H_ {3} BrCl (CF_ {3}) + MgBrX\).
Second, chlorobenzene can also be used as the starting material. First, under the action of a suitable catalyst, chlorobenzene and bromine are introduced into the ortho-position of chlorobenzene through electrophilic substitution to obtain 1-chloro-2-bromobenzene. This catalyst can assist in the polarization of bromine molecules and promote the reaction. The reaction formula is:\ (C_ {6} H_ {5} Cl + Br_ {2}\ stackrel {catalyst} {\ longrightarrow} C_ {6} H_ {4} ClBr + HBr\).
Then, 1-chloro-2-bromobenzene reacts with a trifluoromethylating reagent to introduce trifluoromethyl. This reaction process requires attention to the dosage and reaction conditions of trifluoromethylating reagents to obtain the target product 1-bromo-2-chloro-3- (trifluoromethyl) benzene in high yields. This process is similar to the Grignard reaction principle, and the introduction of groups is achieved by means of interreagent activity.
What are the precautions for storing and transporting 1-bromo-2-chloro-3- (trifluoromethyl) benzene?
When storing and transporting 1 + - + alcohol - 2 + - + ether - 3 - (triethylmethyl) benzene, pay attention to many matters.
Alcohols, many of which are volatile and flammable, must be stored in a cool, ventilated place away from fire and heat sources to prevent the risk of fire and explosion. Containers must also be tightly sealed to avoid volatilization loss or absorption of moisture in the air and affect quality. During transportation, avoid violent vibration and collision to ensure that the packaging is intact.
Ethers are also highly volatile, and their steam and air can form explosive mixtures. The storage environment temperature should be low, and they should not be co-stored with strong oxidants, strong acids, etc., because they may cause violent chemical reactions. When transporting dangerous goods, it is necessary to strictly follow the transportation specifications of dangerous goods, and equip corresponding fire and emergency equipment.
(triethylmethyl) benzene aromatic hydrocarbons are toxic and flammable. Storage should be in a cool, dry and well-ventilated place, away from fire and heat sources. Because it is harmful to human health and contact may cause poisoning, the storage place should be marked and protective measures should be taken. Be careful during transportation to prevent leakage. In the event of leakage, emergency measures should be taken quickly to evacuate people and prevent the spread of pollution. In short, when storing and transporting these three substances, they must be operated in strict accordance with regulations, strengthen safety awareness, and make protection and emergency preparations to ensure the safety of personnel and the environment.
Alcohols, many of which are volatile and flammable, must be stored in a cool, ventilated place away from fire and heat sources to prevent the risk of fire and explosion. Containers must also be tightly sealed to avoid volatilization loss or absorption of moisture in the air and affect quality. During transportation, avoid violent vibration and collision to ensure that the packaging is intact.
Ethers are also highly volatile, and their steam and air can form explosive mixtures. The storage environment temperature should be low, and they should not be co-stored with strong oxidants, strong acids, etc., because they may cause violent chemical reactions. When transporting dangerous goods, it is necessary to strictly follow the transportation specifications of dangerous goods, and equip corresponding fire and emergency equipment.
(triethylmethyl) benzene aromatic hydrocarbons are toxic and flammable. Storage should be in a cool, dry and well-ventilated place, away from fire and heat sources. Because it is harmful to human health and contact may cause poisoning, the storage place should be marked and protective measures should be taken. Be careful during transportation to prevent leakage. In the event of leakage, emergency measures should be taken quickly to evacuate people and prevent the spread of pollution. In short, when storing and transporting these three substances, they must be operated in strict accordance with regulations, strengthen safety awareness, and make protection and emergency preparations to ensure the safety of personnel and the environment.
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