Linshang Chemical
PRODUCTS
1-Bromo-2-Chloro-4,6-Diflorobenzene
Linshang Chemical
|
HS Code |
290602 |
| Chemical Formula | C6H2BrClF2 |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 175 - 177 °C |
| Density | 1.807 g/cm³ |
| Solubility | Insoluble in water, soluble in organic solvents |
| Flash Point | 73 °C |
| Stability | Stable under normal conditions |
As an accredited 1-Bromo-2-Chloro-4,6-Diflorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 1 - bromo - 2 - chloro - 4,6 - difluorobenzene in a sealed, labeled chemical bottle. |
| Storage | 1 - Bromo - 2 - chloro - 4,6 - difluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials. This helps prevent leakage and potential reactions that could occur due to exposure to air, moisture, or incompatible substances. |
| Shipping | 1 - bromo - 2 - chloro - 4,6 - difluorobenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper labeling, secure packaging to prevent leaks during transit. |
Competitive 1-Bromo-2-Chloro-4,6-Diflorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Bromo-2-Chloro-4,6-Diflorobenzene in China?
As a trusted 1-Bromo-2-Chloro-4,6-Diflorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Bromo-2-Chloro-4,6-Diflorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 1-bromo-2-chloro-4,6-difluorobenzene?
1 + -Hydroxy-2-aldehyde-4,6-divinylbenzene, the physical properties of this substance are as follows:
Looking at its state, under room temperature and pressure, it is mostly in the shape of a liquid state. Its color is either transparent and colorless, or slightly light yellow, clear and clear when pure, like glaze.
In terms of its taste, it has a special aromatic smell. This fragrance is not rich and pungent, but has a slightly fresh and unique fragrance. Under specific circumstances, it can be keenly perceived by people.
As for the boiling point, it is about a certain temperature range. Due to the slight difference in specific purity and environmental conditions, it is roughly in a certain temperature range and needs to be accurately measured to determine. The characteristic of boiling point makes it change from liquid state to gaseous state at a specific temperature, which is an important basis for separation and purification operations such as distillation.
Melting point also has corresponding values. Under a specific low temperature, it will solidify from liquid state to solid state, forming a regular or irregular crystal structure.
The density is higher than that of water or less than that of water, depending on its molecular composition and internal structure. This property is related to the phenomenon of floating or sinking when mixed with other liquids such as water, which is of great significance for separation and stratification steps in chemical production and experimental operations.
In terms of solubility, organic solvents such as ethanol and ether often show good solubility and can be miscible with them to form a uniform mixed system. However, in water, the solubility is poor, and it is mostly in a layered state. This property determines its dispersion and reaction behavior in different solvent environments.
Its refractive index is also one of the important physical properties. When light passes through the substance, it will refract. The value of the refractive index reflects the strength of the material's ability to deflect light, which is of reference value for optical materials and related analysis and detection methods.
The above physical properties are all key considerations in many fields such as chemical synthesis, material preparation, analysis and testing, etc., helping researchers to accurately control their application directions and operation points.
Looking at its state, under room temperature and pressure, it is mostly in the shape of a liquid state. Its color is either transparent and colorless, or slightly light yellow, clear and clear when pure, like glaze.
In terms of its taste, it has a special aromatic smell. This fragrance is not rich and pungent, but has a slightly fresh and unique fragrance. Under specific circumstances, it can be keenly perceived by people.
As for the boiling point, it is about a certain temperature range. Due to the slight difference in specific purity and environmental conditions, it is roughly in a certain temperature range and needs to be accurately measured to determine. The characteristic of boiling point makes it change from liquid state to gaseous state at a specific temperature, which is an important basis for separation and purification operations such as distillation.
Melting point also has corresponding values. Under a specific low temperature, it will solidify from liquid state to solid state, forming a regular or irregular crystal structure.
The density is higher than that of water or less than that of water, depending on its molecular composition and internal structure. This property is related to the phenomenon of floating or sinking when mixed with other liquids such as water, which is of great significance for separation and stratification steps in chemical production and experimental operations.
In terms of solubility, organic solvents such as ethanol and ether often show good solubility and can be miscible with them to form a uniform mixed system. However, in water, the solubility is poor, and it is mostly in a layered state. This property determines its dispersion and reaction behavior in different solvent environments.
Its refractive index is also one of the important physical properties. When light passes through the substance, it will refract. The value of the refractive index reflects the strength of the material's ability to deflect light, which is of reference value for optical materials and related analysis and detection methods.
The above physical properties are all key considerations in many fields such as chemical synthesis, material preparation, analysis and testing, etc., helping researchers to accurately control their application directions and operation points.
What are the chemical properties of 1-bromo-2-chloro-4,6-difluorobenzene?
This compound has the structural characteristics of enols and enaldehyde. In the enol part, the hydroxyl group is connected to the double-bonded carbon atom, which makes it acidic and can react with bases. Like the hydroxyl group of alcohols, it can participate in the esterification reaction and form esters with acids under appropriate conditions. However, its enol structure is different from that of ordinary alcohols, because it is conjugated with double bonds, and its stability and reactivity are specific.
The alkenal part, the carbon-carbon double bond and the aldehyde group are conjugated, which enhances the electron delocalization of the molecule, making the reactivity of the aldehyde group different from that of the ordinary aldehyde. This conjugate system makes the molecule prone to electrophilic addition reaction, which attracts electrophilic reagents due to the increase of electron cloud density of the double bond. At the same time, the aldehyde group can carry out common oxidation and reduction reactions. In case of weak oxidants, the aldehyde group can be oxidized to carboxyl groups; in case of strong reducing agents, the aldehyde group can be reduced to alcohol hydroxyl groups.
Furthermore, this compound has good optical activity and conjugation effect due to the presence of multiple conjugated double bonds. The conjugate system causes specific changes in the electron transition after absorbing light energy, and has a unique absorption peak in spectral analysis, which can be used to identify its existence and structure. And the conjugate effect affects the stability and reaction selectivity of molecules, which can be cleverly used in organic synthesis to prepare compounds with specific structures.
In short, the chemical properties of 1,3-pentadiene-2-alcohol-4,6-dienal are rich and diverse, and are of great value in the research and application fields of organic chemistry.
In what fields is 1-bromo-2-chloro-4,6-difluorobenzene used?
1 + -mercury-2-arsenic-4,6-diethyl ether is used in various places. In the field of medicine, mercury used to be used to make medicinal pills to treat scabies and other diseases, but it is now rarely used because of its toxicity; arsenic compounds have been used to treat syphilis and other diseases, and are now rarely used. In the chemical industry, mercury can be used to make thermometers, sphygmomanometers and other instruments, due to its ability to accurately measure; arsenic is used to make pesticides, preservatives, etc., with its bactericidal and insecticidal properties; 4,6-diethyl ether is a common organic solvent. In chemical synthesis, it helps the reactants to dissolve and promote the reaction. In the mining industry, mercury and arsenic are common associated elements, and attention should be paid to their separation and treatment when mining related minerals. In the environmental field, mercury and arsenic are both heavy metal pollutants. Once they enter the environment, they can be enriched through the food chain, endangering the ecology and human health. Therefore, their discharge and treatment need to be strictly controlled. Therefore, 1 + -mercury-2-arsenic-4,6-diethyl ether is used in many fields such as medicine, chemical industry, mining, and the environment. It should be handled with caution to achieve the purpose of rational use and avoiding its harm.
What is the synthesis of 1-bromo-2-chloro-4,6-difluorobenzene?
To prepare 1-bromo-2-iodine-4,6-divinylbenzene, you can follow the following method.
First take an appropriate amount of benzene, blend concentrated sulfuric acid with concentrated nitric acid, and carry out nitrification reaction at a suitable temperature to obtain nitrobenzene. Because the benzene ring has the property of electrophilic substitution, the nitro positive ion is an electrophilic reagent, which can attack the benzene ring, and obtain nitrobenzene through a series of reactions.
The nitrobenzene is reduced to an amino group by using iron powder and hydrochloric acid as a reducing agent to generate aniline. This is based on the principle of redox. Iron powder and hydrochloric acid can provide electrons, which reduce the valence of nitrogen atoms in the nitro group and eventually form an amino group.
2,4,6-tribromoaniline can be obtained by reacting aniline with bromine water. Because the amino group is a strong activating group, the electron cloud density of the benzene ring is greatly increased, and the bromine molecule is polarized by the induction of the benzene ring. Bromine positive ions are easy to attack the benzene ring, and the adjacent and para-activity of the amino group is high, so 2,4,6-tribromoaniline is obtained.
2,4,6-tribromoaniline is reacted with sodium nitrite and hydrochloric acid at low temperature to form a diazonium salt. In this reaction, nitrous acid reacts with hydrochloric acid to form nitrous acid, and nitrous acid reacts with aniline, and the amino group is converted into a diazo group to obtain a diazo salt. Diazo salts are active and stable at low temperatures.
React potassium iodide with the obtained diazonium salt, and the diazonium group is replaced by the iodine atom to obtain 2,4,6-tribromoiodobenzene. This is because iodine ions have strong nucleophilicity and can attack the diazonium group of the diazonium salt, resulting in a nucleophilic substitution reaction.
The coupling reaction of 2,4,6-tribromoiodobenzene with vinylboronic acid was carried out in the presence of palladium catalyst and base. Suzuki coupling reaction can effectively form carbon-carbon bonds, palladium catalyst can promote the reaction, and base can help activate boric acid and stabilize the reaction intermediates.
Through the above series of reactions, the structure of the target molecule is gradually constructed, and 1-bromo-2-iodine-4,6-divinylbenzene can be obtained.
First take an appropriate amount of benzene, blend concentrated sulfuric acid with concentrated nitric acid, and carry out nitrification reaction at a suitable temperature to obtain nitrobenzene. Because the benzene ring has the property of electrophilic substitution, the nitro positive ion is an electrophilic reagent, which can attack the benzene ring, and obtain nitrobenzene through a series of reactions.
The nitrobenzene is reduced to an amino group by using iron powder and hydrochloric acid as a reducing agent to generate aniline. This is based on the principle of redox. Iron powder and hydrochloric acid can provide electrons, which reduce the valence of nitrogen atoms in the nitro group and eventually form an amino group.
2,4,6-tribromoaniline can be obtained by reacting aniline with bromine water. Because the amino group is a strong activating group, the electron cloud density of the benzene ring is greatly increased, and the bromine molecule is polarized by the induction of the benzene ring. Bromine positive ions are easy to attack the benzene ring, and the adjacent and para-activity of the amino group is high, so 2,4,6-tribromoaniline is obtained.
2,4,6-tribromoaniline is reacted with sodium nitrite and hydrochloric acid at low temperature to form a diazonium salt. In this reaction, nitrous acid reacts with hydrochloric acid to form nitrous acid, and nitrous acid reacts with aniline, and the amino group is converted into a diazo group to obtain a diazo salt. Diazo salts are active and stable at low temperatures.
React potassium iodide with the obtained diazonium salt, and the diazonium group is replaced by the iodine atom to obtain 2,4,6-tribromoiodobenzene. This is because iodine ions have strong nucleophilicity and can attack the diazonium group of the diazonium salt, resulting in a nucleophilic substitution reaction.
The coupling reaction of 2,4,6-tribromoiodobenzene with vinylboronic acid was carried out in the presence of palladium catalyst and base. Suzuki coupling reaction can effectively form carbon-carbon bonds, palladium catalyst can promote the reaction, and base can help activate boric acid and stabilize the reaction intermediates.
Through the above series of reactions, the structure of the target molecule is gradually constructed, and 1-bromo-2-iodine-4,6-divinylbenzene can be obtained.
What are the safety precautions for 1-bromo-2-chloro-4,6-difluorobenzene?
Today there is 1-cyanogen-2-chloro-4,6-divinylbenzene. The safety precautions are as follows:
This substance is toxic and can cause damage to the human body when exposed. Inhalation of its volatile gases, or absorption through the skin, accidental ingestion, can cause poisoning. Light dizziness, nausea, vomiting, severe damage to the organs, life-threatening. Therefore, be sure to take good protection when operating, wear a gas mask, protective clothing, protective gloves, and avoid direct contact.
Its flammable, in case of open flames, hot topics are easy to burn and explode. Storage and use should be kept away from fire and heat sources, placed in a cool and well-ventilated place, and stored separately from oxidants according to regulations to prevent danger caused by mutual reaction.
In the place of use, fire extinguishing equipment and leakage emergency treatment equipment should be equipped. In the event of a leak, quickly evacuate unrelated personnel to a safe area and strictly restrict access. Emergency responders wear self-contained positive pressure breathing apparatus and anti-toxic clothing. Do not let leaks come into contact with combustible substances. Small leaks are absorbed with inert materials such as sand and vermiculite; a large number of leaks are built into embankments or excavated for containment, covered with foam to reduce volatilization, and then transferred to a tanker or special collector by pump, recycled or transported to a waste treatment site for disposal.
After operation, thoroughly wash the body and change clothes to prevent residual substances from endangering health. At the same time, the workplace should be well ventilated to reduce its concentration in the air. Relevant personnel need to be professionally trained and operate in strict accordance with the operating procedures.
This substance is toxic and can cause damage to the human body when exposed. Inhalation of its volatile gases, or absorption through the skin, accidental ingestion, can cause poisoning. Light dizziness, nausea, vomiting, severe damage to the organs, life-threatening. Therefore, be sure to take good protection when operating, wear a gas mask, protective clothing, protective gloves, and avoid direct contact.
Its flammable, in case of open flames, hot topics are easy to burn and explode. Storage and use should be kept away from fire and heat sources, placed in a cool and well-ventilated place, and stored separately from oxidants according to regulations to prevent danger caused by mutual reaction.
In the place of use, fire extinguishing equipment and leakage emergency treatment equipment should be equipped. In the event of a leak, quickly evacuate unrelated personnel to a safe area and strictly restrict access. Emergency responders wear self-contained positive pressure breathing apparatus and anti-toxic clothing. Do not let leaks come into contact with combustible substances. Small leaks are absorbed with inert materials such as sand and vermiculite; a large number of leaks are built into embankments or excavated for containment, covered with foam to reduce volatilization, and then transferred to a tanker or special collector by pump, recycled or transported to a waste treatment site for disposal.
After operation, thoroughly wash the body and change clothes to prevent residual substances from endangering health. At the same time, the workplace should be well ventilated to reduce its concentration in the air. Relevant personnel need to be professionally trained and operate in strict accordance with the operating procedures.
Scan to WhatsApp
