Linshang Chemical
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1-Bromo-2-Chloro-4,6-Difluorobenzene
|
HS Code |
698560 |
| Chemical Formula | C6H2BrClF2 |
| Molecular Weight | 227.43 |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | Around 180 - 185 °C |
| Density | Data may vary, typically in a certain range for halogenated benzenes |
| Solubility | Slightly soluble in water, soluble in organic solvents like ethanol, ether |
| Vapor Pressure | Low vapor pressure at room temperature |
| Flash Point | Caution: flammable, flash point data varies by measurement method |
| Stability | Stable under normal conditions, but reactive with strong oxidizing agents |
As an accredited 1-Bromo-2-Chloro-4,6-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - bromo - 2 - chloro - 4,6 - difluorobenzene: Packed in 500 - g bottles for chemical storage. |
| Storage | 1 - Bromo - 2 - chloro - 4,6 - difluorobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Avoid storing it near oxidizing agents or reactive chemicals to prevent potential reactions. Label the storage container clearly for easy identification and safety. |
| Shipping | 1 - Bromo - 2 - chloro - 4,6 - difluorobenzene, a chemical, is shipped in properly sealed, corrosion - resistant containers. Special care is taken to comply with regulations for hazardous chemicals during transport to ensure safety. |
Competitive 1-Bromo-2-Chloro-4,6-Difluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Bromo-2-Chloro-4,6-Difluorobenzene in China?
As a trusted 1-Bromo-2-Chloro-4,6-Difluorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Bromo-2-Chloro-4,6-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 1-bromo-2-chloro-4,6-difluorobenzene?
1 + -Hydroxy-2-aldehyde-4,6-divinylbenzene is one of the organic compounds. Its physical properties are particularly important, as follows:
Looking at its properties, under normal temperature and pressure, 1 + -hydroxy-2-aldehyde-4,6-divinylbenzene is usually in a liquid state. The formation of this state is related to the force of intermolecular interaction. The attractive force and repulsion between molecules reach a balance, resulting in its fluidity and no fixed shape, similar to all common liquids.
As for the color, it is mostly colorless and transparent, just like clear water. Due to the difference in energy levels involved in electron transitions in the molecular structure, it is not within the absorption range of visible light, so the light can pass through smoothly without absorption or scattering, and it is colorless and transparent.
Smell its smell, or have a special fragrance. The source of this aroma lies in its unique molecular structure. The functional groups contained in it interact with specific receptors in the olfactory nerve and are transmitted through the nerve to form a special olfactory perception in the brain. However, this incense is not popular with the public because it may stimulate the olfactory sense.
When it comes to the boiling point, the boiling point of 1 + -hydroxyl-2-aldehyde-4,6-divinylbenzene is quite high. This is due to the existence of strong forces between molecules, such as hydrogen bonds, van der Waals forces, etc. To make it change from a liquid state to a gaseous state, a large amount of energy is required to overcome these forces, so that the molecules break free from each other and escape into the gaseous phase, so the boiling point is very high.
Its melting point cannot be ignored. At a specific temperature, 1 + -hydroxyl-2-aldehyde-4,6-divinylbenzene changes from a solid state to a liquid state. The value of this melting point is determined by the degree of close arrangement and interaction of the molecules. In the solid state, the molecules are arranged in an orderly manner and are closely connected by the interaction force. When heated, the vibration of the molecules is intensified. When the melting point is reached, the ordered structure disintegrates and turns into a liquid state.
In terms of solubility, 1 + -hydroxyl-2-aldehyde-4,6-divinylbenzene has a certain solubility in organic solvents such as ethanol and ether. Due to the principle of "similarity and miscibility", its molecular structure is similar to that of organic solvents. They all contain elements such as hydrocarbons and hydrocarbons, and the intermolecular forces can match each other, so they are soluble; however, in water, the solubility is poor. Water is a polar molecule, and the polarity of 1 + -hydroxyl-2-aldehyde-4,6-divinylbenzene is large, and the interaction force is difficult to match, making it difficult to dissolve in water.
The density of 1 + -hydroxyl-2-aldehyde-4,6-divinylbenzene is slightly smaller than that of water. This is determined by its molecular weight and intermolecular voids. The molecular weight contained in a unit volume is less than that of water, so the density is small. If mixed with water, it often floats on water.
Looking at its properties, under normal temperature and pressure, 1 + -hydroxy-2-aldehyde-4,6-divinylbenzene is usually in a liquid state. The formation of this state is related to the force of intermolecular interaction. The attractive force and repulsion between molecules reach a balance, resulting in its fluidity and no fixed shape, similar to all common liquids.
As for the color, it is mostly colorless and transparent, just like clear water. Due to the difference in energy levels involved in electron transitions in the molecular structure, it is not within the absorption range of visible light, so the light can pass through smoothly without absorption or scattering, and it is colorless and transparent.
Smell its smell, or have a special fragrance. The source of this aroma lies in its unique molecular structure. The functional groups contained in it interact with specific receptors in the olfactory nerve and are transmitted through the nerve to form a special olfactory perception in the brain. However, this incense is not popular with the public because it may stimulate the olfactory sense.
When it comes to the boiling point, the boiling point of 1 + -hydroxyl-2-aldehyde-4,6-divinylbenzene is quite high. This is due to the existence of strong forces between molecules, such as hydrogen bonds, van der Waals forces, etc. To make it change from a liquid state to a gaseous state, a large amount of energy is required to overcome these forces, so that the molecules break free from each other and escape into the gaseous phase, so the boiling point is very high.
Its melting point cannot be ignored. At a specific temperature, 1 + -hydroxyl-2-aldehyde-4,6-divinylbenzene changes from a solid state to a liquid state. The value of this melting point is determined by the degree of close arrangement and interaction of the molecules. In the solid state, the molecules are arranged in an orderly manner and are closely connected by the interaction force. When heated, the vibration of the molecules is intensified. When the melting point is reached, the ordered structure disintegrates and turns into a liquid state.
In terms of solubility, 1 + -hydroxyl-2-aldehyde-4,6-divinylbenzene has a certain solubility in organic solvents such as ethanol and ether. Due to the principle of "similarity and miscibility", its molecular structure is similar to that of organic solvents. They all contain elements such as hydrocarbons and hydrocarbons, and the intermolecular forces can match each other, so they are soluble; however, in water, the solubility is poor. Water is a polar molecule, and the polarity of 1 + -hydroxyl-2-aldehyde-4,6-divinylbenzene is large, and the interaction force is difficult to match, making it difficult to dissolve in water.
The density of 1 + -hydroxyl-2-aldehyde-4,6-divinylbenzene is slightly smaller than that of water. This is determined by its molecular weight and intermolecular voids. The molecular weight contained in a unit volume is less than that of water, so the density is small. If mixed with water, it often floats on water.
What are the chemical properties of 1-bromo-2-chloro-4,6-difluorobenzene?
Eh! The chemical properties of 1,2-epoxy-4,6-divinylbenzene are particularly interesting. This compound contains epoxy groups and vinyl groups, so it has unique reactivity.
Epoxy groups are active in nature. When encountering nucleophiles, it is easy to open a ring. If it encounters alcohols, the hydroxyl groups of alcohols act as nucleophiles to attack the carbon atoms on the epoxy ring, causing the epoxy ring to break and forming products containing hydroxyl groups and ether bonds. This reaction can be carried out under mild conditions and often requires the catalysis of bases or Lewis acids. This reaction is very important in organic synthesis and can be used to construct complex molecular structures and enrich the functional groups of compounds.
In addition, its vinyl is also significantly active. Vinyl is rich in electrons and can participate in many addition reactions. In free radical addition reactions, free radicals attack the double bonds of vinyl, initiating a chain reaction and forming new carbon-carbon bonds. Common free radical initiators, such as peroxides, can promote such reactions. In addition, vinyl can also undergo polymerization reactions. Under the action of an appropriate catalyst, the vinyl groups of multiple 1,2-epoxy-4,6-divinylbenzene molecules are connected to each other to form a polymer. This polymer can be further crosslinked and cured due to its epoxy structure, improving the mechanical properties and thermal stability of the material.
At the same time, the molecular structure of 1,2-epoxy-4,6-divinylbenzene endows it with certain solubility and volatility. It has good solubility in common organic solvents such as toluene and dichloromethane, which is convenient for its reaction operation in solution systems. However, its volatility is relatively low, and it is easier to control its escape during use, which is conducive to experimental operation and safe production.
In summary, 1,2-epoxy-4,6-divinylbenzene has broad application prospects in the fields of organic synthesis and material preparation due to its epoxy and vinyl activities and specific physical properties.
Epoxy groups are active in nature. When encountering nucleophiles, it is easy to open a ring. If it encounters alcohols, the hydroxyl groups of alcohols act as nucleophiles to attack the carbon atoms on the epoxy ring, causing the epoxy ring to break and forming products containing hydroxyl groups and ether bonds. This reaction can be carried out under mild conditions and often requires the catalysis of bases or Lewis acids. This reaction is very important in organic synthesis and can be used to construct complex molecular structures and enrich the functional groups of compounds.
In addition, its vinyl is also significantly active. Vinyl is rich in electrons and can participate in many addition reactions. In free radical addition reactions, free radicals attack the double bonds of vinyl, initiating a chain reaction and forming new carbon-carbon bonds. Common free radical initiators, such as peroxides, can promote such reactions. In addition, vinyl can also undergo polymerization reactions. Under the action of an appropriate catalyst, the vinyl groups of multiple 1,2-epoxy-4,6-divinylbenzene molecules are connected to each other to form a polymer. This polymer can be further crosslinked and cured due to its epoxy structure, improving the mechanical properties and thermal stability of the material.
At the same time, the molecular structure of 1,2-epoxy-4,6-divinylbenzene endows it with certain solubility and volatility. It has good solubility in common organic solvents such as toluene and dichloromethane, which is convenient for its reaction operation in solution systems. However, its volatility is relatively low, and it is easier to control its escape during use, which is conducive to experimental operation and safe production.
In summary, 1,2-epoxy-4,6-divinylbenzene has broad application prospects in the fields of organic synthesis and material preparation due to its epoxy and vinyl activities and specific physical properties.
What are the main uses of 1-bromo-2-chloro-4,6-difluorobenzene?
In the realm of alchemy cultivation, these substances are often the key to assisting in refining alchemy sand and reconciling yin and yang. In the art of covering alchemy, if you want to have long-term vision and transcendental sainthood, you need to borrow external objects to help you. 1 + - - - 2 - - - 4,6 - dienyne has unique properties. In the furnace cauldron, it can make all kinds of drugs better integrate, promote their chemical reactions, and reach a delicate state, so that the effect of medicinal pills is better, so as to help practitioners open up meridians and improve their skills.
It is also indispensable in the industry of weapon casting. The ancient craftsmen who forged swords often used this thing to add to the sword blank. Due to its characteristics, it can make the sword body tough and abnormally sharp. The sword has been tempered here, and the blade is like frost and snow, and the iron is cut like mud. On the battlefield, it is a sharp weapon for warriors to kill the enemy, to protect the family and the country, and to safeguard peace.
It is also very useful in the way of healing wounds and helping the world. Doctors take its essence and make it into ointment pill powder. It can promote blood circulation, remove blood stasis, and activate meridians. It has a significant effect on bruises and meridian blockages. It can make the injured recover quickly, relieve pain, and return to a healthy state.
In addition to the construction of the Kit-Kit mechanism, 1 + - < 2 - < - 4,6 - dienyne can also be used as a source of power or a material for key components. The Kit mechanism relies on its unique properties, either to operate freely, or to be sturdy and durable. It plays an important role in the art of Qimen's escape armor, or to protect secret places, or to transmit messages.
In short, 1 + - < - < - 4, 6 - dienyne plays an extraordinary role in many fields, reflecting the wisdom of the ancients in using natural things to benefit life, practice, and warfare.
It is also indispensable in the industry of weapon casting. The ancient craftsmen who forged swords often used this thing to add to the sword blank. Due to its characteristics, it can make the sword body tough and abnormally sharp. The sword has been tempered here, and the blade is like frost and snow, and the iron is cut like mud. On the battlefield, it is a sharp weapon for warriors to kill the enemy, to protect the family and the country, and to safeguard peace.
It is also very useful in the way of healing wounds and helping the world. Doctors take its essence and make it into ointment pill powder. It can promote blood circulation, remove blood stasis, and activate meridians. It has a significant effect on bruises and meridian blockages. It can make the injured recover quickly, relieve pain, and return to a healthy state.
In addition to the construction of the Kit-Kit mechanism, 1 + - < 2 - < - 4,6 - dienyne can also be used as a source of power or a material for key components. The Kit mechanism relies on its unique properties, either to operate freely, or to be sturdy and durable. It plays an important role in the art of Qimen's escape armor, or to protect secret places, or to transmit messages.
In short, 1 + - < - < - 4, 6 - dienyne plays an extraordinary role in many fields, reflecting the wisdom of the ancients in using natural things to benefit life, practice, and warfare.
What are the synthesis methods of 1-bromo-2-chloro-4,6-difluorobenzene?
To prepare 1-bromo-2-iodine-4,6-divinylbenzene, the following methods can be used:
First, benzene is used as the initial raw material. Schilling benzene and bromine are brominated under the catalysis of iron bromide to obtain bromobenzene. Bromobenzene reacts with iodine under specific catalysts and suitable conditions to generate 1-bromo-2-iodobenzene. Subsequently, 1-bromo-2-iodobenzene reacts with vinyl Grignard reagents (such as vinyl magnesium bromide) in anhydrous ether and other solvents. After a series of steps, vinyl groups can be introduced to obtain the target product 1-bromo-2-iodine-4,6-divinylbenzene. In this process, the reaction conditions of each step are quite critical. For example, the bromine reaction needs to control the amount of bromine and the reaction temperature to prevent the formation of polybrominated products. When reacting with vinyl Grignard reagents, the system needs to be kept anhydrous and oxygen-free, otherwise Grignard reagents are easy to decompose.
Second, start from divinylbenzene. Divinylbenzene is first protected by a protective group, such as an allyl silicon reagent. After that, the unprotected benzene ring position is halogenated, and a bromine atom is introduced first. N-bromosuccinimide (NBS) can be used for bromination under the action of light or an initiator to obtain an intermediate containing a bromine atom. Then, an iodine atom is introduced, and the iodine element and an appropriate oxidation reagent, such as a mixture of hydrogen peroxide and sulfuric acid, can be used to promote the iodation reaction. Finally, the protective group is removed to obtain 1-bromo-2-iodine-4,6-divinylbenzene. This route focuses on the selection and removal conditions of the protecting group. The protecting group must be stable in the halogenation reaction, and the removal does not affect other groups.
Third, other suitable aromatic derivatives are used as raw materials. If there are aromatic hydrocarbons containing appropriate substituents, through reasonable functional group conversion, an intermediate similar to the structure of the target product is first constructed, and then through halogenation, vinylation and other reactions, 1-bromo-2-iodine-4,6-divinylbenzene is gradually prepared. For example, some aromatic hydrocarbons with functional groups that can be converted into bromine, iodine and vinyl are converted through hydrolysis, substitution and elimination. This approach requires great familiarity with various functional group reactions and carefully designed reaction routes to achieve the purpose of efficient synthesis.
First, benzene is used as the initial raw material. Schilling benzene and bromine are brominated under the catalysis of iron bromide to obtain bromobenzene. Bromobenzene reacts with iodine under specific catalysts and suitable conditions to generate 1-bromo-2-iodobenzene. Subsequently, 1-bromo-2-iodobenzene reacts with vinyl Grignard reagents (such as vinyl magnesium bromide) in anhydrous ether and other solvents. After a series of steps, vinyl groups can be introduced to obtain the target product 1-bromo-2-iodine-4,6-divinylbenzene. In this process, the reaction conditions of each step are quite critical. For example, the bromine reaction needs to control the amount of bromine and the reaction temperature to prevent the formation of polybrominated products. When reacting with vinyl Grignard reagents, the system needs to be kept anhydrous and oxygen-free, otherwise Grignard reagents are easy to decompose.
Second, start from divinylbenzene. Divinylbenzene is first protected by a protective group, such as an allyl silicon reagent. After that, the unprotected benzene ring position is halogenated, and a bromine atom is introduced first. N-bromosuccinimide (NBS) can be used for bromination under the action of light or an initiator to obtain an intermediate containing a bromine atom. Then, an iodine atom is introduced, and the iodine element and an appropriate oxidation reagent, such as a mixture of hydrogen peroxide and sulfuric acid, can be used to promote the iodation reaction. Finally, the protective group is removed to obtain 1-bromo-2-iodine-4,6-divinylbenzene. This route focuses on the selection and removal conditions of the protecting group. The protecting group must be stable in the halogenation reaction, and the removal does not affect other groups.
Third, other suitable aromatic derivatives are used as raw materials. If there are aromatic hydrocarbons containing appropriate substituents, through reasonable functional group conversion, an intermediate similar to the structure of the target product is first constructed, and then through halogenation, vinylation and other reactions, 1-bromo-2-iodine-4,6-divinylbenzene is gradually prepared. For example, some aromatic hydrocarbons with functional groups that can be converted into bromine, iodine and vinyl are converted through hydrolysis, substitution and elimination. This approach requires great familiarity with various functional group reactions and carefully designed reaction routes to achieve the purpose of efficient synthesis.
What are the precautions for storing and transporting 1-bromo-2-chloro-4,6-difluorobenzene?
"Tiangong Kaiwu" says: "All kinds of inks are made by burning smoke and condensing." Smoke is the foundation of ink, condensing smoke into ink, and careful preparation, storage and transportation are required during this period.
Preparation of smoke and ink, raw materials are essential. Tung oil, clear oil, lard and other oils, pine branches, fir branches and other wood, can be the source of smoke. For example, to make 1-oil fume-2-paint smoke-4,6-diolefin ink, high-quality raw materials need to be selected to get good smoke. The oil fume made by tung oil is delicate and glossy; the paint smoke is black and strong, all of which are good products.
When storing, avoid moisture and moisture. Ink likes dryness and abhors dampness. Moisture can easily cause ink to become moldy and deteriorate, which will damage its quality. It should be placed in a dry and ventilated place, and should not be in the same place as moisture-prone objects. It is also necessary to prevent high temperature. High temperature will soften and deform the ink, which will affect the use. During storage, a desiccant can be built into the ink cartridge to absorb moisture and keep the ink quality stable.
During transportation, handling it with care is the first priority. The ink body is brittle and hard, and it is easy to break without paying attention. The packaging should be tight, and it should be padded with soft objects, such as cotton wool, soft paper, etc., to cushion the vibration. Long-distance transportation should pay more attention to the climate and road conditions. In summer, prevent sun exposure and heat up, and in winter,
Well-prepared 1-oil fume-2-paint smoke-4,6-diolefin ink, if it can be carefully cared for in storage and transportation, it will be able to retain its quality for a long time for literati to splash ink, write beautiful articles, and paint Danqing scrolls.
Preparation of smoke and ink, raw materials are essential. Tung oil, clear oil, lard and other oils, pine branches, fir branches and other wood, can be the source of smoke. For example, to make 1-oil fume-2-paint smoke-4,6-diolefin ink, high-quality raw materials need to be selected to get good smoke. The oil fume made by tung oil is delicate and glossy; the paint smoke is black and strong, all of which are good products.
When storing, avoid moisture and moisture. Ink likes dryness and abhors dampness. Moisture can easily cause ink to become moldy and deteriorate, which will damage its quality. It should be placed in a dry and ventilated place, and should not be in the same place as moisture-prone objects. It is also necessary to prevent high temperature. High temperature will soften and deform the ink, which will affect the use. During storage, a desiccant can be built into the ink cartridge to absorb moisture and keep the ink quality stable.
During transportation, handling it with care is the first priority. The ink body is brittle and hard, and it is easy to break without paying attention. The packaging should be tight, and it should be padded with soft objects, such as cotton wool, soft paper, etc., to cushion the vibration. Long-distance transportation should pay more attention to the climate and road conditions. In summer, prevent sun exposure and heat up, and in winter,
Well-prepared 1-oil fume-2-paint smoke-4,6-diolefin ink, if it can be carefully cared for in storage and transportation, it will be able to retain its quality for a long time for literati to splash ink, write beautiful articles, and paint Danqing scrolls.
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