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1-Bromo-2-Chloro-4-Fluoro-3-Methylbenzene
Linshang Chemical
|
HS Code |
229646 |
| Name | 1-Bromo-2-Chloro-4-Fluoro-3-Methylbenzene |
| Molecular Formula | C7H5BrClF |
| Molecular Weight | 225.47 |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | Around 200 - 210 °C |
| Density | Approx. 1.6 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Flash Point | Approx. 85 - 95 °C |
| Odor | Characteristic aromatic odor |
| Vapor Pressure | Low at room temperature |
As an accredited 1-Bromo-2-Chloro-4-Fluoro-3-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 g of 1 - bromo - 2 - chloro - 4 - fluoro - 3 - methylbenzene in a sealed glass bottle. |
| Storage | 1 - Bromo - 2 - chloro - 4 - fluoro - 3 - methylbenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. It should be kept in a tightly - sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Store it separately from oxidizing agents and reactive chemicals to prevent potential chemical reactions. |
| Shipping | 1 - bromo - 2 - chloro - 4 - fluoro - 3 - methylbenzene, a potentially hazardous chemical, will be shipped in well - sealed, corrosion - resistant containers. Special handling procedures will be followed to ensure safe transportation, adhering to all relevant regulations. |
Competitive 1-Bromo-2-Chloro-4-Fluoro-3-Methylbenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Where to Buy 1-Bromo-2-Chloro-4-Fluoro-3-Methylbenzene in China?
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Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Bromo-2-Chloro-4-Fluoro-3-Methylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 1-bromo-2-chloro-4-fluoro-3-methylbenzene?
A certain alcohol, ether, and alkane substances have different physical properties, which are described by you today.
Let's talk about 1-bromo-2-chloro-4-fluoro-3-methylbenzene first. This compound has unique properties because it contains a variety of halogen atoms and methyl groups. It is volatile to a certain extent and has a special odor at room temperature, or as a colorless to light yellow liquid. Due to the high electronegativity of halogen atoms and the enhancement of molecular polarity, it has good solubility in organic solvents, such as ethanol and ether. Its boiling point is affected by the intermolecular force. Due to the increase in relative molecular mass and polarity, the boiling point is slightly higher than that of benzene. The density is greater than that of water, and it will sink to the bottom when placed in water.
Furthermore, from the perspective of the characteristics of halogen atoms, bromine, chlorine, and fluorine atoms endow the substance with certain chemical activities, and reactions such as nucleophilic substitution can occur, which also affect its physical properties. And due to the existence of the benzene ring conjugate system, its physical properties are different on the basis of aromatic compounds. Under light, heat and other conditions, the stability of its physical state may change, such as the rate of volatilization will vary due to environmental changes.
Let's talk about 1-bromo-2-chloro-4-fluoro-3-methylbenzene first. This compound has unique properties because it contains a variety of halogen atoms and methyl groups. It is volatile to a certain extent and has a special odor at room temperature, or as a colorless to light yellow liquid. Due to the high electronegativity of halogen atoms and the enhancement of molecular polarity, it has good solubility in organic solvents, such as ethanol and ether. Its boiling point is affected by the intermolecular force. Due to the increase in relative molecular mass and polarity, the boiling point is slightly higher than that of benzene. The density is greater than that of water, and it will sink to the bottom when placed in water.
Furthermore, from the perspective of the characteristics of halogen atoms, bromine, chlorine, and fluorine atoms endow the substance with certain chemical activities, and reactions such as nucleophilic substitution can occur, which also affect its physical properties. And due to the existence of the benzene ring conjugate system, its physical properties are different on the basis of aromatic compounds. Under light, heat and other conditions, the stability of its physical state may change, such as the rate of volatilization will vary due to environmental changes.
What are the chemical properties of 1-bromo-2-chloro-4-fluoro-3-methylbenzene?
1 + -Mercury-2-bromo-4-3-methylpyridine, where "
Mercury, commonly known as mercury, is a liquid metal at room temperature. Its chemical properties are relatively stable and do not react with dilute hydrochloric acid and dilute sulfuric acid, but it can react with strong oxidizing acids such as hot concentrated sulfuric acid and nitric acid. For example, mercury reacts with hot concentrated sulfuric acid to form mercury sulfate, sulfur dioxide and water. Mercury is volatile to a certain extent, and mercury vapor is toxic. In the air, mercury can slowly react with oxygen to form mercury oxide. Mercury can dissolve many metals to form amalgams, such as sodium amalgam with sodium.
Bromine, a dark reddish-brown liquid at room temperature, is volatile and has a strong pungent odor. Bromine is a strong oxidizing agent and can react directly with many metals, such as reacting with iron to form iron bromide. Bromine can also react with some non-metals, such as reacting with hydrogen under heat or light conditions to form hydrogen bromide. In water, it partially reacts with water to form hydrobromic acid and hypobromic acid. Bromine can undergo addition reactions with unsaturated hydrocarbons and can also replace hydrogen atoms on aromatic hydrocarbons.
Methylpyridine, taking 2-methylpyridine as an example, is basic, and the lone pair electrons on the nitrogen atom can bind protons. The electrophilic substitution reaction can occur, and the electron cloud density on the pyridine ring increases due to the electron supply effect of methyl groups. The substitution reaction mainly occurs at the β position of the pyridine ring. It can be oxidized by oxidants, such as methyl groups can be oxidized to carboxyl groups under appropriate conditions. At the same time, methyl pyridine can also form complexes with some metal salts.
Mercury, commonly known as mercury, is a liquid metal at room temperature. Its chemical properties are relatively stable and do not react with dilute hydrochloric acid and dilute sulfuric acid, but it can react with strong oxidizing acids such as hot concentrated sulfuric acid and nitric acid. For example, mercury reacts with hot concentrated sulfuric acid to form mercury sulfate, sulfur dioxide and water. Mercury is volatile to a certain extent, and mercury vapor is toxic. In the air, mercury can slowly react with oxygen to form mercury oxide. Mercury can dissolve many metals to form amalgams, such as sodium amalgam with sodium.
Bromine, a dark reddish-brown liquid at room temperature, is volatile and has a strong pungent odor. Bromine is a strong oxidizing agent and can react directly with many metals, such as reacting with iron to form iron bromide. Bromine can also react with some non-metals, such as reacting with hydrogen under heat or light conditions to form hydrogen bromide. In water, it partially reacts with water to form hydrobromic acid and hypobromic acid. Bromine can undergo addition reactions with unsaturated hydrocarbons and can also replace hydrogen atoms on aromatic hydrocarbons.
Methylpyridine, taking 2-methylpyridine as an example, is basic, and the lone pair electrons on the nitrogen atom can bind protons. The electrophilic substitution reaction can occur, and the electron cloud density on the pyridine ring increases due to the electron supply effect of methyl groups. The substitution reaction mainly occurs at the β position of the pyridine ring. It can be oxidized by oxidants, such as methyl groups can be oxidized to carboxyl groups under appropriate conditions. At the same time, methyl pyridine can also form complexes with some metal salts.
What are the main uses of 1-bromo-2-chloro-4-fluoro-3-methylbenzene?
1 + - + mercury + - + 2 + - + arsenic + - + 4 + - + lead + - + 3 + - + methylmercury. What is the main use of mercury? Mercury is a toxic material. In the past, it was often used in chlorine-producing materials in the workplace, but because of its toxicity, it has been used for many purposes today. It has also been used in measuring instruments such as manufacturing, blood, etc., with the characteristics of its liquid and temperature. However, today, due to health concerns, other alternative materials are often used.
Arsenic was often used in ancient times, such as in some Chinese methods. However, arsenic is toxic, and has been rarely used for generations. In terms of engineering, arsenic compounds can be used in semi-fabricated materials, such as arsenide, for optical devices, integrated circuits and other fields. In addition, they have also been used in industrial applications, but their use is also limited due to the harm of environmental organisms.
< br It is toxic and easy to accumulate in organisms. The positive use of methylmercury can be said, but it is a serious problem of environmental pollution. Because it can spread to food, it is most harmful to human health, such as the famous water disease, which is caused by eating water contaminated with methylmercury. Therefore, it is necessary to make every effort to prevent it from spreading in the environment.
Arsenic was often used in ancient times, such as in some Chinese methods. However, arsenic is toxic, and has been rarely used for generations. In terms of engineering, arsenic compounds can be used in semi-fabricated materials, such as arsenide, for optical devices, integrated circuits and other fields. In addition, they have also been used in industrial applications, but their use is also limited due to the harm of environmental organisms.
< br It is toxic and easy to accumulate in organisms. The positive use of methylmercury can be said, but it is a serious problem of environmental pollution. Because it can spread to food, it is most harmful to human health, such as the famous water disease, which is caused by eating water contaminated with methylmercury. Therefore, it is necessary to make every effort to prevent it from spreading in the environment.
What are the synthesis methods of 1-bromo-2-chloro-4-fluoro-3-methylbenzene?
To prepare 1-aldehyde-2-alkane-4-ene-3-methylbenzene, there are several methods as follows.
First, it can be obtained by oxidation of the corresponding alcohol. A suitable alcohol is used as the starting material and a suitable oxidant is selected. For example, under mild conditions, active manganese dioxide can be used, which can selectively oxidize alcohol hydroxyl groups to aldehyde groups, and has little effect on other unsaturated bonds in the molecule. If the alcohol structure is an alcohol containing 2-alkane-4-ene-3-methylbenzene, the conversion to the target aldehyde can be realized under the action of active manganese dioxide.
Second, it can be converted into halogenated hydrocarbons. First, halogenated hydrocarbons with halogenated atoms and a 2-alkane-4-ene-3-methylbenzene structure are obtained, and then suitable metal reagents, such as magnesium, are used to make Grignard reagents. Then it reacts with suitable carbonyl compounds, such as formaldehyde, and then hydrolyzes to obtain the target aldehyde. In this process, Grignard reagents are added to formaldehyde, and aldehyde groups are introduced to build the desired carbon skeleton.
Third, it can be reduced by carboxylic acid derivatives. If there are carboxylic acid derivatives containing 2-alkane-4-ene-3-methylbenzene, such as acid chloride, with mild reducing agents, such as appropriate variants of lithium aluminum hydride, such as tri-tert-butoxy lithium aluminum hydride, acid chloride can be reduced to aldehyde. This reducing agent can realize the conversion of acid chloride to aldehyde without excessive reduction.
Fourth, allyl rearrangement can be used. Compounds with suitable substituents that can undergo allyl rearrangement are first prepared. Under suitable conditions, such as specific acid-base catalysis or heating, allyl rearrangement is promoted, and then aldehyde groups are introduced through subsequent reactions to achieve the synthesis of 1-aldehyde-2-alkane-4-ene-3-methylbenzene.
First, it can be obtained by oxidation of the corresponding alcohol. A suitable alcohol is used as the starting material and a suitable oxidant is selected. For example, under mild conditions, active manganese dioxide can be used, which can selectively oxidize alcohol hydroxyl groups to aldehyde groups, and has little effect on other unsaturated bonds in the molecule. If the alcohol structure is an alcohol containing 2-alkane-4-ene-3-methylbenzene, the conversion to the target aldehyde can be realized under the action of active manganese dioxide.
Second, it can be converted into halogenated hydrocarbons. First, halogenated hydrocarbons with halogenated atoms and a 2-alkane-4-ene-3-methylbenzene structure are obtained, and then suitable metal reagents, such as magnesium, are used to make Grignard reagents. Then it reacts with suitable carbonyl compounds, such as formaldehyde, and then hydrolyzes to obtain the target aldehyde. In this process, Grignard reagents are added to formaldehyde, and aldehyde groups are introduced to build the desired carbon skeleton.
Third, it can be reduced by carboxylic acid derivatives. If there are carboxylic acid derivatives containing 2-alkane-4-ene-3-methylbenzene, such as acid chloride, with mild reducing agents, such as appropriate variants of lithium aluminum hydride, such as tri-tert-butoxy lithium aluminum hydride, acid chloride can be reduced to aldehyde. This reducing agent can realize the conversion of acid chloride to aldehyde without excessive reduction.
Fourth, allyl rearrangement can be used. Compounds with suitable substituents that can undergo allyl rearrangement are first prepared. Under suitable conditions, such as specific acid-base catalysis or heating, allyl rearrangement is promoted, and then aldehyde groups are introduced through subsequent reactions to achieve the synthesis of 1-aldehyde-2-alkane-4-ene-3-methylbenzene.
What are the environmental effects of 1-bromo-2-chloro-4-fluoro-3-methylbenzene?
Mercury, bromine, chlorine, iodine, and methylmercury have a huge impact on the environment.
Mercury is highly toxic. At room temperature, it can evaporate into mercury vapor. If inhaled, it can damage the nervous system, kidneys, etc. In water bodies, mercury can be converted into methylmercury through microbial action, which is particularly toxic. Methylmercury is lipophilic and easily enriched in organisms. It accumulates layer by layer along the food chain to the top predator. The concentration can be extremely high. If people eat it, it will cause serious harm to the body. In the past, Minamata disease in Japan was caused by methylmercury poisoning.
Bromine and chlorine are widely used in the chemical industry. However, compounds containing bromine and chlorine can affect the atmospheric ozone layer if they are released indiscriminately. Bromide and chloride can release active halogen atoms under ultraviolet radiation, which can catalyze ozone decomposition and cause ozone layer depletion, causing the earth to lose this important protective layer. Ultraviolet radiation increases greatly, endangering all living things.
Although iodine is an essential trace element for the human body, an appropriate amount of iodine is beneficial to the human body and can maintain the normal function of the thyroid gland. However, if the iodine content in the environment is unbalanced, there are also disadvantages. Excessive iodine enters water, soil, or affects plant growth, and may affect animal and human health through the food chain. If there is insufficient iodine in the environment, it is easy to cause the epidemic of diseases such as goiter.
As mentioned above, methylmercury not only endangers human health, but also seriously damages the ecosystem. Aquatic organisms are poisoned by methylmercury, which may reduce the population and biodiversity, thereby disrupting the balance of the entire aquatic ecosystem and affecting its material cycle and energy flow.
All of these show that mercury, bromine, chlorine, iodine, and methylmercury have complex and far-reaching effects on the environment. We should be careful and try our best to reduce their harm to the environment and protect ecological safety.
Mercury is highly toxic. At room temperature, it can evaporate into mercury vapor. If inhaled, it can damage the nervous system, kidneys, etc. In water bodies, mercury can be converted into methylmercury through microbial action, which is particularly toxic. Methylmercury is lipophilic and easily enriched in organisms. It accumulates layer by layer along the food chain to the top predator. The concentration can be extremely high. If people eat it, it will cause serious harm to the body. In the past, Minamata disease in Japan was caused by methylmercury poisoning.
Bromine and chlorine are widely used in the chemical industry. However, compounds containing bromine and chlorine can affect the atmospheric ozone layer if they are released indiscriminately. Bromide and chloride can release active halogen atoms under ultraviolet radiation, which can catalyze ozone decomposition and cause ozone layer depletion, causing the earth to lose this important protective layer. Ultraviolet radiation increases greatly, endangering all living things.
Although iodine is an essential trace element for the human body, an appropriate amount of iodine is beneficial to the human body and can maintain the normal function of the thyroid gland. However, if the iodine content in the environment is unbalanced, there are also disadvantages. Excessive iodine enters water, soil, or affects plant growth, and may affect animal and human health through the food chain. If there is insufficient iodine in the environment, it is easy to cause the epidemic of diseases such as goiter.
As mentioned above, methylmercury not only endangers human health, but also seriously damages the ecosystem. Aquatic organisms are poisoned by methylmercury, which may reduce the population and biodiversity, thereby disrupting the balance of the entire aquatic ecosystem and affecting its material cycle and energy flow.
All of these show that mercury, bromine, chlorine, iodine, and methylmercury have complex and far-reaching effects on the environment. We should be careful and try our best to reduce their harm to the environment and protect ecological safety.
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