Linshang Chemical
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1-Bromo-2-Chloro-4-Fluorobenzene
Linshang Chemical
|
HS Code |
907594 |
| Chemical Formula | C6H3BrClF |
| Molar Mass | 225.44 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | Approximately 197 - 199 °C |
| Density | Around 1.7 - 1.8 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Vapor Pressure | Low at room temperature |
As an accredited 1-Bromo-2-Chloro-4-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 1 - bromo - 2 - chloro - 4 - fluorobenzene packaged in a sealed glass bottle. |
| Storage | 1 - Bromo - 2 - chloro - 4 - fluorobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent leakage and exposure to air or moisture. Store it separately from oxidizing agents, strong acids, and bases to avoid potential chemical reactions. Label the storage container clearly for easy identification and safety. |
| Shipping | 1 - bromo - 2 - chloro - 4 - fluorobenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, with proper labeling for its toxic and reactive nature to ensure safe transportation. |
Competitive 1-Bromo-2-Chloro-4-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Bromo-2-Chloro-4-Fluorobenzene in China?
As a trusted 1-Bromo-2-Chloro-4-Fluorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Bromo-2-Chloro-4-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 1-bromo-2-chloro-4-fluorobenzene?
Mercury, bromine, astatine, and cesium are all special substances with unique physical properties. The details are as follows:
Mercury is the only metal that is liquid at room temperature and pressure. Its color is silver-white, with a metallic luster, and it has good fluidity. The density is very high, reaching 13.59 grams/cubic centimeter, which is higher than that of common metals such as iron and copper. Therefore, it is placed in other liquids and often sinks to the bottom. The melting point is extremely low, -38.87 ° C, and the boiling point is only 356.6 ° C. Mercury has good electrical conductivity, but relatively weak thermal conductivity. Its surface tension is high, it drops on the plane, and it often aggregates into a spherical shape.
Bromine is a liquid non-metallic element at room temperature and pressure. Dark brown-red, with a strong pungent odor, toxic and corrosive. The density is 3.119 g/cm3, which is larger than water, so in bromine water, bromine sinks at the bottom. Melting point -7.2 ° C, boiling point 58.78 ° C, volatile, and reddish-brown bromine vapor can be seen in the air. Bromine is slightly soluble in water, soluble in organic solvents, such as carbon tetrachloride, benzene, etc., and its solubility in organic solvents is greater than that in water.
Astatin is a very unstable radioactive element, and its content is very small in nature. Due to its short half-life, research is limited. According to theoretical speculation and a few experiments, astatine may be a dark solid. The melting point and boiling point are relatively high, because with the increase of the atomic number of halogen elements, the melting point and boiling point show an upward trend. Although astatine has certain metallic properties, it is still a non-metallic element in nature. Its chemical properties are similar to other elements in the halogen group, such as the formation of halides.
Cesium is an alkali metal element. It is silver-white with a slight golden luster and soft in quality. It can be easily cut with a knife. The density is 1.879 g/cm3, which is larger than water. The melting point is very low, only 28.44 ° C. It melts into a liquid when heated slightly. Cesium is extremely reactive and reacts violently when exposed to water, and even causes an explosion to generate cesium hydroxide and hydrogen. It is easily oxidized in the air and needs to be stored in inert gas or kerosene to isolate air and water.
Mercury is the only metal that is liquid at room temperature and pressure. Its color is silver-white, with a metallic luster, and it has good fluidity. The density is very high, reaching 13.59 grams/cubic centimeter, which is higher than that of common metals such as iron and copper. Therefore, it is placed in other liquids and often sinks to the bottom. The melting point is extremely low, -38.87 ° C, and the boiling point is only 356.6 ° C. Mercury has good electrical conductivity, but relatively weak thermal conductivity. Its surface tension is high, it drops on the plane, and it often aggregates into a spherical shape.
Bromine is a liquid non-metallic element at room temperature and pressure. Dark brown-red, with a strong pungent odor, toxic and corrosive. The density is 3.119 g/cm3, which is larger than water, so in bromine water, bromine sinks at the bottom. Melting point -7.2 ° C, boiling point 58.78 ° C, volatile, and reddish-brown bromine vapor can be seen in the air. Bromine is slightly soluble in water, soluble in organic solvents, such as carbon tetrachloride, benzene, etc., and its solubility in organic solvents is greater than that in water.
Astatin is a very unstable radioactive element, and its content is very small in nature. Due to its short half-life, research is limited. According to theoretical speculation and a few experiments, astatine may be a dark solid. The melting point and boiling point are relatively high, because with the increase of the atomic number of halogen elements, the melting point and boiling point show an upward trend. Although astatine has certain metallic properties, it is still a non-metallic element in nature. Its chemical properties are similar to other elements in the halogen group, such as the formation of halides.
Cesium is an alkali metal element. It is silver-white with a slight golden luster and soft in quality. It can be easily cut with a knife. The density is 1.879 g/cm3, which is larger than water. The melting point is very low, only 28.44 ° C. It melts into a liquid when heated slightly. Cesium is extremely reactive and reacts violently when exposed to water, and even causes an explosion to generate cesium hydroxide and hydrogen. It is easily oxidized in the air and needs to be stored in inert gas or kerosene to isolate air and water.
What are the chemical properties of 1-bromo-2-chloro-4-fluorobenzene?
Mercury, bromine, astatine, and francium are all chemical elements, and their chemical properties are unique.
Mercury is a metal that is liquid at room temperature. Its color is silver-white, with a metallic luster, and its fluidity is quite good. The chemical properties of mercury are relatively stable, and it is not easy to combine directly with oxygen. However, it can also react with strong oxidants. Mercury can dissolve many metals and form amalgams. This property is used in metallurgy and other fields. However, mercury and its compounds are many toxic. If accidentally exposed to or inhaled mercury vapor, it can endanger human health and cause damage to the nervous system, kidneys and other organs.
Bromine is the only non-metallic element that is liquid at room temperature and pressure. Its color is red-brown, with a strong pungent odor, and is highly corrosive. Bromine is chemically active, a strong oxidizing agent, and can react with most metals and some non-metals. In organic synthesis, bromine is often used as a brominating agent, introducing bromine atoms to change the properties of compounds. In nature, bromine exists in seawater and other water bodies in the form of bromide.
astatine is a highly unstable radioactive element. Because of its short half-life, it is present in very little in nature. The chemical properties of astatine are similar to those of halogen elements and are oxidizing. However, due to research limitations, its many properties remain to be explored in depth. Theoretically speculated that astatine may be similar to other halogens and can react with metals and non-metals to form corresponding compounds.
Francium is also a radioactive element and is highly radioactive. Its chemical properties are active and belong to alkali metal elements. Similar to sodium, potassium and other elements of the same family, francium reacts violently in water to generate hydrogen and hydroxides, and the reaction is extremely violent, and a lot of heat is released at the same time. Due to the extremely strong radioactivity and short half-life of francium, it is extremely difficult to prepare and study, so the understanding of its detailed chemical properties is limited.
Mercury is a metal that is liquid at room temperature. Its color is silver-white, with a metallic luster, and its fluidity is quite good. The chemical properties of mercury are relatively stable, and it is not easy to combine directly with oxygen. However, it can also react with strong oxidants. Mercury can dissolve many metals and form amalgams. This property is used in metallurgy and other fields. However, mercury and its compounds are many toxic. If accidentally exposed to or inhaled mercury vapor, it can endanger human health and cause damage to the nervous system, kidneys and other organs.
Bromine is the only non-metallic element that is liquid at room temperature and pressure. Its color is red-brown, with a strong pungent odor, and is highly corrosive. Bromine is chemically active, a strong oxidizing agent, and can react with most metals and some non-metals. In organic synthesis, bromine is often used as a brominating agent, introducing bromine atoms to change the properties of compounds. In nature, bromine exists in seawater and other water bodies in the form of bromide.
astatine is a highly unstable radioactive element. Because of its short half-life, it is present in very little in nature. The chemical properties of astatine are similar to those of halogen elements and are oxidizing. However, due to research limitations, its many properties remain to be explored in depth. Theoretically speculated that astatine may be similar to other halogens and can react with metals and non-metals to form corresponding compounds.
Francium is also a radioactive element and is highly radioactive. Its chemical properties are active and belong to alkali metal elements. Similar to sodium, potassium and other elements of the same family, francium reacts violently in water to generate hydrogen and hydroxides, and the reaction is extremely violent, and a lot of heat is released at the same time. Due to the extremely strong radioactivity and short half-life of francium, it is extremely difficult to prepare and study, so the understanding of its detailed chemical properties is limited.
What are the main uses of 1-bromo-2-chloro-4-fluorobenzene?
Mercury, bromine, astatine, and radon are all chemical elements, and they are widely used.
Mercury is a liquid metal at room temperature, and silver light flows. In ancient alchemy, mercury was an essential medicine, and alchemists wanted to use it to change and seek the method of longevity. Although absurd, it also showed the weight of mercury at that time. And mercury in metallurgy can extract precious metals such as gold and silver, and by virtue of the nature of amalgam, impurities can be separated and pure. In the production of equipment, mercury is used in thermometers and barometers, because it changes with temperature and pressure, its volume is obvious and its display is accurate. However, mercury is toxic, if used carelessly, it will cause harm, damage people's internal organs, and confuse people's minds.
Bromine, a dark reddish-brown fuming liquid with a foul odor. In medicine, bromide can be used as a sedative, relieving the tension of the nerves and calming the restless heart. In chemical industry, bromine is used to make dyes and flame retardants. Dyes have bright color and enhanced fastness due to bromine; flame retardants add bromine, which can stop the spread of fire and keep things safe. In agriculture, bromine compounds are fumigants, which remove pests, kill pathogens, and protect the abundance of crops.
Astine, radioactive, is rare in the world. Although it is difficult to use it on a large scale, in scientific research, the study of its properties helps to solve the mystery of atomic structure and decay laws. In the field of medical radioactivity tracing, astatine is expected to become a sharp weapon. According to its radioactivity, it can detect changes in human physiology and pathology, and help doctors perform surgery.
Radon, a colorless and odorless radioactive gas. In geological exploration, the concentration of radon can be detected, underground structures can be explored, and traces of ore veins can be found, which is a guide for mining. In medical treatment, if the hot spring contains an appropriate amount of radon, bathing can treat rheumatism, neuralgia and other diseases, and its radioactivity can stimulate the human body and adjust the function of the body. However, if radon accumulates in the room, if it is inhaled for a long time, it will damage the lungs and cause cancer, endangering life.
Mercury, bromine, astatine, and radon each have their own characteristics. If they are used properly, they will benefit people. If they are used carelessly, they will harm the common people. They should be used carefully to check their advantages and disadvantages and avoid disadvantages.
Mercury is a liquid metal at room temperature, and silver light flows. In ancient alchemy, mercury was an essential medicine, and alchemists wanted to use it to change and seek the method of longevity. Although absurd, it also showed the weight of mercury at that time. And mercury in metallurgy can extract precious metals such as gold and silver, and by virtue of the nature of amalgam, impurities can be separated and pure. In the production of equipment, mercury is used in thermometers and barometers, because it changes with temperature and pressure, its volume is obvious and its display is accurate. However, mercury is toxic, if used carelessly, it will cause harm, damage people's internal organs, and confuse people's minds.
Bromine, a dark reddish-brown fuming liquid with a foul odor. In medicine, bromide can be used as a sedative, relieving the tension of the nerves and calming the restless heart. In chemical industry, bromine is used to make dyes and flame retardants. Dyes have bright color and enhanced fastness due to bromine; flame retardants add bromine, which can stop the spread of fire and keep things safe. In agriculture, bromine compounds are fumigants, which remove pests, kill pathogens, and protect the abundance of crops.
Astine, radioactive, is rare in the world. Although it is difficult to use it on a large scale, in scientific research, the study of its properties helps to solve the mystery of atomic structure and decay laws. In the field of medical radioactivity tracing, astatine is expected to become a sharp weapon. According to its radioactivity, it can detect changes in human physiology and pathology, and help doctors perform surgery.
Radon, a colorless and odorless radioactive gas. In geological exploration, the concentration of radon can be detected, underground structures can be explored, and traces of ore veins can be found, which is a guide for mining. In medical treatment, if the hot spring contains an appropriate amount of radon, bathing can treat rheumatism, neuralgia and other diseases, and its radioactivity can stimulate the human body and adjust the function of the body. However, if radon accumulates in the room, if it is inhaled for a long time, it will damage the lungs and cause cancer, endangering life.
Mercury, bromine, astatine, and radon each have their own characteristics. If they are used properly, they will benefit people. If they are used carelessly, they will harm the common people. They should be used carefully to check their advantages and disadvantages and avoid disadvantages.
What are the synthesis methods of 1-bromo-2-chloro-4-fluorobenzene?
To make 1-alkyne-2-ene-4-heptyne, the following ancient methods can be used.
First, it is formed by the reaction of halogenated hydrocarbons and sodium alkynide. First, take an appropriate halogenated hydrocarbon, such as halogenated alkanes or halogenated alkenes, and react with the prepared sodium alkynide in a suitable solvent. Sodium alkynide can be obtained by the action of alkynes and strong bases such as sodium amide in liquids such as ammonia. Halogen atoms in halogenated hydrocarbons are active, and when encountering alkynyl negative ions in sodium alkynide, a nucleophilic substitution reaction occurs, and the halogen atom is replaced by an alkynyl group, and then the target alkynene compound is formed. This reaction requires attention to control the reaction conditions. The choice of solvent is very critical, and an anhydrous environment is appropriate to prevent the hydrolysis of sodium alkylate. The reaction temperature also needs to be precisely controlled. Too high or too low will affect the yield and product purity.
Second, the addition reaction of alkynes is used. Appropriate alkynes are used as starting materials to add them to alkenyl-containing reagents under the action of suitable catalysts. For example, in the presence of certain transition metal catalysts, alkynes can be added to alkenyl halides. In this process, catalyst activity and selectivity are very important, which can guide the reaction in the direction of the target product. At the same time, it is necessary to pay attention to the proportion of each substance in the reaction system. Improper proportions can easily lead to side reactions and generate other isomers or multi-substituted products.
Third, with the help of organometallic reagents. For example, organolithium reagents or Grignard reagents are used to react with corresponding halogenates or carbonyl compounds. First prepare organometallic reagents with specific structures, and then react with halogenates containing alkenyl or alkynyl structures. After a series of nucleophilic substitution or addition steps, the carbon skeleton of the target molecule is constructed. In this method, the preparation of organometallic reagents needs to be carried out under strict anhydrous and anaerobic conditions. Due to its extremely high activity, it is easy to deteriorate in contact with water or oxygen, which affects the subsequent reaction process
First, it is formed by the reaction of halogenated hydrocarbons and sodium alkynide. First, take an appropriate halogenated hydrocarbon, such as halogenated alkanes or halogenated alkenes, and react with the prepared sodium alkynide in a suitable solvent. Sodium alkynide can be obtained by the action of alkynes and strong bases such as sodium amide in liquids such as ammonia. Halogen atoms in halogenated hydrocarbons are active, and when encountering alkynyl negative ions in sodium alkynide, a nucleophilic substitution reaction occurs, and the halogen atom is replaced by an alkynyl group, and then the target alkynene compound is formed. This reaction requires attention to control the reaction conditions. The choice of solvent is very critical, and an anhydrous environment is appropriate to prevent the hydrolysis of sodium alkylate. The reaction temperature also needs to be precisely controlled. Too high or too low will affect the yield and product purity.
Second, the addition reaction of alkynes is used. Appropriate alkynes are used as starting materials to add them to alkenyl-containing reagents under the action of suitable catalysts. For example, in the presence of certain transition metal catalysts, alkynes can be added to alkenyl halides. In this process, catalyst activity and selectivity are very important, which can guide the reaction in the direction of the target product. At the same time, it is necessary to pay attention to the proportion of each substance in the reaction system. Improper proportions can easily lead to side reactions and generate other isomers or multi-substituted products.
Third, with the help of organometallic reagents. For example, organolithium reagents or Grignard reagents are used to react with corresponding halogenates or carbonyl compounds. First prepare organometallic reagents with specific structures, and then react with halogenates containing alkenyl or alkynyl structures. After a series of nucleophilic substitution or addition steps, the carbon skeleton of the target molecule is constructed. In this method, the preparation of organometallic reagents needs to be carried out under strict anhydrous and anaerobic conditions. Due to its extremely high activity, it is easy to deteriorate in contact with water or oxygen, which affects the subsequent reaction process
What are the precautions for storing and transporting 1-bromo-2-chloro-4-fluorobenzene?
When storing and transporting mercury, bromine, neon, and liquid argon, many matters need to be paid attention to.
Mercury is very toxic. When storing, a sealed container must be used to prevent the volatilization of mercury and the escape of mercury vapor, which endangers the people around it. The material of the container must also be carefully selected, such as glass and porcelain, which have a small affinity for mercury, and it is necessary to regularly check the container for damage and leakage. During the transportation process, it is necessary to strictly follow the transportation specifications of hazardous chemicals, and make protective and warning signs to prevent accidental leakage.
Bromine, which is highly corrosive and volatile, should be stored in a cool and ventilated place, away from fire and heat sources. It should be contained in a corrosion-resistant container, such as a glass bottle and equipped with a glass stopper. Rubber stoppers should not be used, because it can corrode the rubber. When transporting, the packaging must be tight to ensure that there is no risk of leakage, and the transporter must be familiar with its emergency treatment methods.
Neon is an inert gas. Although it is chemically stable, it is still necessary to ensure that the container is well sealed during storage to prevent gas escape. Because it is mostly stored at high pressure, it is necessary to pay attention to the temperature and pressure of the storage environment to avoid the pressure rise caused by excessive temperature and cause the container to break. When transporting, it is also necessary to prevent the container from being violently collided to ensure the safety of transportation.
Liquid argon is a low-temperature liquefied gas. Storage requires a special low-temperature insulated container to maintain its low-temperature liquid state. The thermal insulation performance of the container is crucial, otherwise the liquid argon will vaporize due to the absorption of external heat, causing the pressure in the container to increase. During transportation, the temperature and pressure of the liquid argon should be monitored in real time, and the transportation vehicle should be equipped with corresponding low temperature protection and emergency equipment. Transportation personnel should also take cold protection and safety measures.
Mercury is very toxic. When storing, a sealed container must be used to prevent the volatilization of mercury and the escape of mercury vapor, which endangers the people around it. The material of the container must also be carefully selected, such as glass and porcelain, which have a small affinity for mercury, and it is necessary to regularly check the container for damage and leakage. During the transportation process, it is necessary to strictly follow the transportation specifications of hazardous chemicals, and make protective and warning signs to prevent accidental leakage.
Bromine, which is highly corrosive and volatile, should be stored in a cool and ventilated place, away from fire and heat sources. It should be contained in a corrosion-resistant container, such as a glass bottle and equipped with a glass stopper. Rubber stoppers should not be used, because it can corrode the rubber. When transporting, the packaging must be tight to ensure that there is no risk of leakage, and the transporter must be familiar with its emergency treatment methods.
Neon is an inert gas. Although it is chemically stable, it is still necessary to ensure that the container is well sealed during storage to prevent gas escape. Because it is mostly stored at high pressure, it is necessary to pay attention to the temperature and pressure of the storage environment to avoid the pressure rise caused by excessive temperature and cause the container to break. When transporting, it is also necessary to prevent the container from being violently collided to ensure the safety of transportation.
Liquid argon is a low-temperature liquefied gas. Storage requires a special low-temperature insulated container to maintain its low-temperature liquid state. The thermal insulation performance of the container is crucial, otherwise the liquid argon will vaporize due to the absorption of external heat, causing the pressure in the container to increase. During transportation, the temperature and pressure of the liquid argon should be monitored in real time, and the transportation vehicle should be equipped with corresponding low temperature protection and emergency equipment. Transportation personnel should also take cold protection and safety measures.
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