Linshang Chemical
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1-Bromo-2-Chloro-4-Methoxybenzene
Linshang Chemical
|
HS Code |
415824 |
| Chemical Formula | C7H6BrClO |
| Molar Mass | 221.48 g/mol |
| Appearance | A colorless to light yellow liquid or solid |
| Boiling Point | Approximately 245 - 247 °C |
| Melting Point | Around 37 - 39 °C |
| Density | 1.59 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Flash Point | 102 °C |
| Purity | Typically available in high purity grades like 95%+ |
| Odor | Characteristic, aromatic odor |
As an accredited 1-Bromo-2-Chloro-4-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 1 - bromo - 2 - chloro - 4 - methoxybenzene packaged in a sealed glass bottle. |
| Storage | 1 - Bromo - 2 - chloro - 4 - methoxybenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive chemicals. Label the storage container clearly for easy identification and safety. |
| Shipping | 1 - bromo - 2 - chloro - 4 - methoxybenzene should be shipped in well - sealed, corrosion - resistant containers. Label it clearly as a chemical. Ensure compliance with hazardous materials shipping regulations during transportation to prevent leakage and ensure safety. |
Competitive 1-Bromo-2-Chloro-4-Methoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Bromo-2-Chloro-4-Methoxybenzene in China?
As a trusted 1-Bromo-2-Chloro-4-Methoxybenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Bromo-2-Chloro-4-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 1-bromo-2-chloro-4-methoxybenzene?
The chemical properties of 1 + - + ether + - + 2 + - + alkane + - + 4 + - + methoxy phenyl group are diverse and vary depending on the environment.
The ether part, 1-ether functional group, has ether communication. The oxygen atom of the ether has 10%, and its chemical phase is determined, and it is often used as a dissolution of the reaction. However, under the action of an acid such as iodic acid (HI), the ether can be cracked to form iodoalkanols. For example, when the 1-ether encounters HI, the ether can combine to form an alcohol, and the lower part of the ether can form iodoalkanes.
2 -alkane part, with alkyl properties. Alkane and alkyl, the chemical properties are determined, and the acid, alkyl and oxidation properties are not reflected under normal conditions. However, under light or high light, free radicals can be generated to replace antibodies, such as chlorine (such as chlorine,\ (Cl_ {2}\)). When illuminated, the atom is gradually replaced by chlorine atoms to form chloroalkanes.
4 -methoxy phenyl moiety, methoxy (\ (- OCH_ {3}\))) provides a daughter group, which increases the density of the phenyl sub-cloud. This group makes benzene more likely to be substituted and antibodies, and the antibodies are mainly generated in the methoxy group. In addition, the oxygen atom of the methoxy group has solitary ions on the oxygen atom, which can be ligated to form a complex.
, 1 + - + ether + - + 2 + - + alkyl + - + 4 + - + methoxy phenyl compounds, which have both ether, alkyl and the chemical properties of methoxy benzene, under different anti-molecules, show the characteristics of enrichment.
The ether part, 1-ether functional group, has ether communication. The oxygen atom of the ether has 10%, and its chemical phase is determined, and it is often used as a dissolution of the reaction. However, under the action of an acid such as iodic acid (HI), the ether can be cracked to form iodoalkanols. For example, when the 1-ether encounters HI, the ether can combine to form an alcohol, and the lower part of the ether can form iodoalkanes.
2 -alkane part, with alkyl properties. Alkane and alkyl, the chemical properties are determined, and the acid, alkyl and oxidation properties are not reflected under normal conditions. However, under light or high light, free radicals can be generated to replace antibodies, such as chlorine (such as chlorine,\ (Cl_ {2}\)). When illuminated, the atom is gradually replaced by chlorine atoms to form chloroalkanes.
4 -methoxy phenyl moiety, methoxy (\ (- OCH_ {3}\))) provides a daughter group, which increases the density of the phenyl sub-cloud. This group makes benzene more likely to be substituted and antibodies, and the antibodies are mainly generated in the methoxy group. In addition, the oxygen atom of the methoxy group has solitary ions on the oxygen atom, which can be ligated to form a complex.
, 1 + - + ether + - + 2 + - + alkyl + - + 4 + - + methoxy phenyl compounds, which have both ether, alkyl and the chemical properties of methoxy benzene, under different anti-molecules, show the characteristics of enrichment.
What are the main applications of 1-bromo-2-chloro-4-methoxybenzene?
1 + -Mercury-2-arsenic-4-methoxyphenyl is mainly used in many fields, such as medicine, chemical industry, materials, etc.
In the field of medicine, mercury has been used in some external drugs in the past, but due to its toxicity, its application has been greatly limited today; arsenic is also recorded in ancient medicine, and a small amount of arsenic agents can be finely prepared or used for the treatment of specific diseases, but its toxicity must also be treated with caution; methoxybenzene is of great significance in drug synthesis and is often used as a key structural unit to improve the physical and chemical properties and biological activities of drugs. Many anti-cancer and anti-inflammatory drugs contain this group in the molecular structure.
In the chemical industry, mercury can be used for mercury cathodic electrolysis in the chlor-alkali industry, but due to its great harm to the environment and human body, this process has been gradually replaced; arsenic compounds can be used as pigments, preservatives, etc. However, due to environmental considerations, the application is also being reduced; methoxyphenyl derivatives are often used as intermediates in organic synthesis for the preparation of various fine chemicals, such as fragrances, surfactants, etc.
In the field of materials, mercury-containing materials have been used in batteries, fluorescent lamps and other products. However, due to environmental protection needs, the use of mercury-containing materials is being strictly controlled. Arsenic can participate in the preparation of semiconductor materials to adjust the electrical properties of materials. Methoxyphenyl-modified materials may exhibit unique optical, electrical or adsorption properties, and have great application potential in optoelectronic materials, adsorption materials, etc.
In short, although 1 + -mercury-2-arsenic-4-methoxyphenyl has various applications in different fields, with the development of science and technology and the enhancement of environmental awareness, its application is also constantly adjusted and optimized to achieve the purpose of safety, environmental protection and high efficiency.
In the field of medicine, mercury has been used in some external drugs in the past, but due to its toxicity, its application has been greatly limited today; arsenic is also recorded in ancient medicine, and a small amount of arsenic agents can be finely prepared or used for the treatment of specific diseases, but its toxicity must also be treated with caution; methoxybenzene is of great significance in drug synthesis and is often used as a key structural unit to improve the physical and chemical properties and biological activities of drugs. Many anti-cancer and anti-inflammatory drugs contain this group in the molecular structure.
In the chemical industry, mercury can be used for mercury cathodic electrolysis in the chlor-alkali industry, but due to its great harm to the environment and human body, this process has been gradually replaced; arsenic compounds can be used as pigments, preservatives, etc. However, due to environmental considerations, the application is also being reduced; methoxyphenyl derivatives are often used as intermediates in organic synthesis for the preparation of various fine chemicals, such as fragrances, surfactants, etc.
In the field of materials, mercury-containing materials have been used in batteries, fluorescent lamps and other products. However, due to environmental protection needs, the use of mercury-containing materials is being strictly controlled. Arsenic can participate in the preparation of semiconductor materials to adjust the electrical properties of materials. Methoxyphenyl-modified materials may exhibit unique optical, electrical or adsorption properties, and have great application potential in optoelectronic materials, adsorption materials, etc.
In short, although 1 + -mercury-2-arsenic-4-methoxyphenyl has various applications in different fields, with the development of science and technology and the enhancement of environmental awareness, its application is also constantly adjusted and optimized to achieve the purpose of safety, environmental protection and high efficiency.
What is the preparation method of 1-bromo-2-chloro-4-methoxybenzene?
To prepare 1-bromo-2-chloro-4-methoxybenzene, follow the following method.
Take an appropriate amount of p-methoxyphenol as the starting material. Place it in a suitable reaction vessel and add an appropriate amount of solvent, such as dichloromethane, to help the reaction proceed uniformly.
Then, under low temperature and stirring conditions, slowly add the solution containing the brominating agent dropwise. The brominating agent can be mixed with liquid bromine and an appropriate amount of catalyst, such as iron powder or iron tribromide. The rate of dropwise addition should be carefully controlled to prevent the reaction from being too violent. The purpose of this step is to precisely replace the hydrogen atom of the phenolic hydroxyl ortho-position with bromine atoms to generate 2-bromo-4-methoxyphenol.
After the bromination reaction is completed, the pure 2-bromo-4-methoxyphenol is obtained through separation and purification. Then place it in another reaction vessel and re-add a suitable solvent.
Next, at a certain temperature and in the presence of a catalyst, chlorine gas is introduced. Chlorine reacts with 2-bromo-4-methoxyphenol to replace the hydrogen atom at a specific position on the benzene ring, and finally produces 1-bromo-2-chloro-4-methoxybenzene.
After the reaction is completed, high-purity target products can be obtained by conventional separation methods such as extraction, distillation, recrystallization, etc. During the whole process, the control of reaction conditions, the proportion of raw materials, and the monitoring of each step of the reaction are all crucial, which are related to the yield and purity of the product.
Take an appropriate amount of p-methoxyphenol as the starting material. Place it in a suitable reaction vessel and add an appropriate amount of solvent, such as dichloromethane, to help the reaction proceed uniformly.
Then, under low temperature and stirring conditions, slowly add the solution containing the brominating agent dropwise. The brominating agent can be mixed with liquid bromine and an appropriate amount of catalyst, such as iron powder or iron tribromide. The rate of dropwise addition should be carefully controlled to prevent the reaction from being too violent. The purpose of this step is to precisely replace the hydrogen atom of the phenolic hydroxyl ortho-position with bromine atoms to generate 2-bromo-4-methoxyphenol.
After the bromination reaction is completed, the pure 2-bromo-4-methoxyphenol is obtained through separation and purification. Then place it in another reaction vessel and re-add a suitable solvent.
Next, at a certain temperature and in the presence of a catalyst, chlorine gas is introduced. Chlorine reacts with 2-bromo-4-methoxyphenol to replace the hydrogen atom at a specific position on the benzene ring, and finally produces 1-bromo-2-chloro-4-methoxybenzene.
After the reaction is completed, high-purity target products can be obtained by conventional separation methods such as extraction, distillation, recrystallization, etc. During the whole process, the control of reaction conditions, the proportion of raw materials, and the monitoring of each step of the reaction are all crucial, which are related to the yield and purity of the product.
What are the precautions for storing and transporting 1-bromo-2-chloro-4-methoxybenzene?
1 + -Mercury-2-arsenic-4-methoxyphenyl should pay attention to the following things during storage and transportation:
First, because of its toxicity and potential hazards, mercury and arsenic must be treated with special methods. The storage place must be dry, cool and well ventilated, away from fire, heat and oxidants. Once these substances are heated or come into contact with oxidants, they may react violently and cause dangerous emergencies.
Second, storage equipment is also essential. It needs to be stored in a closed and corrosion-resistant container to prevent leakage. Mercury is easy to evaporate into mercury vapor, and if it leaks into the environment, it can be harmful to the human body and the environment. The same is true for arsenic, which leaks or contaminates soil and water sources.
Third, when transporting, it is necessary to act in strict accordance with relevant regulations and standards. Professional transportation companies and personnel should be selected, and the transportation vehicles should be equipped with necessary emergency equipment and protective equipment. If there is a leak on the way, effective measures can be taken immediately to deal with it.
Fourth, people who operate and come into contact with it must wear professional protective equipment, such as protective clothing, gloves, protective masks, etc. Avoid direct contact with these substances on the skin and respiratory tract to prevent poisoning. And after the operation is completed, it must be properly cleaned to ensure that there is no residue.
Fifth, obvious warning signs should be set up at the place of storage and transportation to remind everyone that this is where dangerous goods are located and should not be approached or touched at will. And regularly check and maintain the storage environment and transportation equipment to ensure their safety and reliability, and prevent problems before they occur, so as to ensure the safety of personnel and the environment.
First, because of its toxicity and potential hazards, mercury and arsenic must be treated with special methods. The storage place must be dry, cool and well ventilated, away from fire, heat and oxidants. Once these substances are heated or come into contact with oxidants, they may react violently and cause dangerous emergencies.
Second, storage equipment is also essential. It needs to be stored in a closed and corrosion-resistant container to prevent leakage. Mercury is easy to evaporate into mercury vapor, and if it leaks into the environment, it can be harmful to the human body and the environment. The same is true for arsenic, which leaks or contaminates soil and water sources.
Third, when transporting, it is necessary to act in strict accordance with relevant regulations and standards. Professional transportation companies and personnel should be selected, and the transportation vehicles should be equipped with necessary emergency equipment and protective equipment. If there is a leak on the way, effective measures can be taken immediately to deal with it.
Fourth, people who operate and come into contact with it must wear professional protective equipment, such as protective clothing, gloves, protective masks, etc. Avoid direct contact with these substances on the skin and respiratory tract to prevent poisoning. And after the operation is completed, it must be properly cleaned to ensure that there is no residue.
Fifth, obvious warning signs should be set up at the place of storage and transportation to remind everyone that this is where dangerous goods are located and should not be approached or touched at will. And regularly check and maintain the storage environment and transportation equipment to ensure their safety and reliability, and prevent problems before they occur, so as to ensure the safety of personnel and the environment.
What are the effects of 1-bromo-2-chloro-4-methoxybenzene on the environment and human health?
The impact of 1 + -mercury-2-arsenic-4-methoxyphenyl on the environment and human health is really a matter of people's livelihood. Mercury is a highly toxic metal. It can be migrated and transformed in various ways in the natural environment. If released in water, it can be converted into methylmercury by microorganisms, which is particularly toxic. After ingestion by aquatic organisms such as fish, it will accumulate in the body. If eaten by humans, methylmercury easily penetrates the blood-brain barrier and the placental barrier, damaging the nervous system. Children are particularly susceptible, which can cause mental retardation, movement disorders, etc.
Arsenic is also a toxic element. Arsenic pollution in the environment may be due to natural geological activities or human industrial and mining activities. Soil contaminated with arsenic can affect plant growth, and arsenic enrichment in crops can endanger the food chain. Long-term exposure to arsenic-containing environments in the human body can cause skin lesions such as hyperpigmentation and hyperkeratosis, and is associated with a variety of cancers, especially skin cancer and lung cancer.
As for 4-methoxyphenyl, as an organic compound, it may have applications in industrial production, daily chemicals and other fields. However, its potential harm to the environment and ecology should not be underestimated. In aquatic ecosystems, or affect the growth, reproduction and behavior of aquatic organisms. For the human body, although the relevant research may not be as detailed as mercury and arsenic, some organic compounds are bioaccumulative and toxic, long-term exposure or interference with the endocrine system, affecting the normal physiological functions of the human body.
Therefore, such substances should be strictly monitored and controlled to protect the environment and public health.
Arsenic is also a toxic element. Arsenic pollution in the environment may be due to natural geological activities or human industrial and mining activities. Soil contaminated with arsenic can affect plant growth, and arsenic enrichment in crops can endanger the food chain. Long-term exposure to arsenic-containing environments in the human body can cause skin lesions such as hyperpigmentation and hyperkeratosis, and is associated with a variety of cancers, especially skin cancer and lung cancer.
As for 4-methoxyphenyl, as an organic compound, it may have applications in industrial production, daily chemicals and other fields. However, its potential harm to the environment and ecology should not be underestimated. In aquatic ecosystems, or affect the growth, reproduction and behavior of aquatic organisms. For the human body, although the relevant research may not be as detailed as mercury and arsenic, some organic compounds are bioaccumulative and toxic, long-term exposure or interference with the endocrine system, affecting the normal physiological functions of the human body.
Therefore, such substances should be strictly monitored and controlled to protect the environment and public health.
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