Linshang Chemical
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1-Bromo-2-Chloro-4-Methylbenzene
Linshang Chemical
|
HS Code |
902883 |
| Chemical Formula | C7H6BrCl |
| Molecular Weight | 207.48 |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | Around 225 - 227 °C |
| Density | Around 1.55 - 1.60 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Flash Point | Around 98 °C |
| Odor | Characteristic aromatic odor |
| Stability | Stable under normal conditions, but avoid heat, flames, and strong oxidizing agents |
As an accredited 1-Bromo-2-Chloro-4-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - bromo - 2 - chloro - 4 - methylbenzene in 500 - gram bottles, well - sealed. |
| Storage | 1 - Bromo - 2 - chloro - 4 - methylbenzene should be stored in a cool, well - ventilated area, away from heat, sparks, and open flames. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, bases, and reactive chemicals to prevent potential reactions. Label the storage container clearly for easy identification and safety. |
| Shipping | 1 - bromo - 2 - chloro - 4 - methylbenzene is shipped in well - sealed, corrosion - resistant containers. It's transported following strict chemical shipping regulations, ensuring proper handling to prevent leakage and potential hazards during transit. |
Competitive 1-Bromo-2-Chloro-4-Methylbenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Bromo-2-Chloro-4-Methylbenzene in China?
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Bromo-2-Chloro-4-Methylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 1-bromo-2-chloro-4-methylbenzene?
1 + - + ether + - + 2 + - + alkane + - + 4 + - + methylnaphthalene, this is an organic compound. Ethers have unique physical properties. Usually, ether compounds are mostly liquid at room temperature, and the boiling point is lower than that of alcohols of the same molecular weight. This is because ether molecules cannot form hydrogen bonds, and the intermolecular force is weak. The polarity of ethers is relatively small, and their solubility in water is limited, but they can be miscible with many organic solvents, such as ethanol and acetone, because of their similar compatibility.
As for alkanes, they are saturated hydrocarbons. Their physical properties are quite typical. Small molecules of alkanes, such as methane and ethane, are gaseous at room temperature and pressure. As the number of carbon atoms increases, the boiling point and melting point gradually increase. Alkanes containing 5 to 16 carbon atoms are mostly liquid at room temperature, while those containing more than 17 carbon atoms are mostly solid. The density of alkanes is less than that of water, and they are insoluble in water. The chemical properties of alkanes are relatively stable, because their carbon-carbon single bond and carbon-hydrogen single bond are relatively strong.
4-methylnaphthalene is a fused cyclic aromatic hydrocarbon. The melting point of naphthalene is 80.2 ° C, and the boiling point is 218 ° C. The physical properties of 4-methylnaphthalene have changed due to the introduction of methyl. Compared with naphthalene, the melting point and boiling point of 4-methylnaphthalene may be fine-tuned, and the molecular polarity may change due to the use of methyl as the donating group, and the solubility in organic solvents may also be At the same time, its physical properties such as density and vapor pressure will vary due to structural changes.
As for alkanes, they are saturated hydrocarbons. Their physical properties are quite typical. Small molecules of alkanes, such as methane and ethane, are gaseous at room temperature and pressure. As the number of carbon atoms increases, the boiling point and melting point gradually increase. Alkanes containing 5 to 16 carbon atoms are mostly liquid at room temperature, while those containing more than 17 carbon atoms are mostly solid. The density of alkanes is less than that of water, and they are insoluble in water. The chemical properties of alkanes are relatively stable, because their carbon-carbon single bond and carbon-hydrogen single bond are relatively strong.
4-methylnaphthalene is a fused cyclic aromatic hydrocarbon. The melting point of naphthalene is 80.2 ° C, and the boiling point is 218 ° C. The physical properties of 4-methylnaphthalene have changed due to the introduction of methyl. Compared with naphthalene, the melting point and boiling point of 4-methylnaphthalene may be fine-tuned, and the molecular polarity may change due to the use of methyl as the donating group, and the solubility in organic solvents may also be At the same time, its physical properties such as density and vapor pressure will vary due to structural changes.
What are the chemical properties of 1-bromo-2-chloro-4-methylbenzene?
1 + -Hydroxy-2-aldehyde-4-methylnaphthalene, the chemical properties of this substance are as follows:
- ** Physical properties **: At room temperature, or as a solid, due to strong intermolecular forces, its melting and boiling point has a certain height. It has a certain solubility in common organic solvents such as ethanol and ether. Due to the principle of similar compatibility, its structure is compatible with organic solvents.
- ** Oxidation reaction **: The aldehyde group in the molecule is active in nature. In case of strong oxidants such as potassium permanganate, the aldehyde group can be oxidized to a carboxyl group to obtain derivatives containing carboxyl groups. If treated with mild oxidants, such as Torun reagent or Feilin reagent, the aldehyde group is also oxidized. The former produces silver mirror phenomenon, and the latter produces brick red precipitation, which is a typical oxidation reaction characteristic of aldehyde groups.
- ** Addition reaction **: The carbon and oxygen double bond in the aldehyde group has electrophilicity and can be added with a variety of nucleophiles. In case of alcohols, under acid-catalyzed conditions, acetalylation can occur to form acetal structures. This reaction is often used as a carbonyl protection method in organic synthesis. The naphthalene ring part, although aromatic and relatively stable, can also undergo electrophilic addition reaction under specific conditions, such as strong Lewis acid catalysis and high reagent activity, and new groups can be introduced into the naphthalene ring.
- ** Substitution reaction **: The methyl group is attached to the naphthalene ring, and the hydrogen atom on the methyl group has a certain activity under the influence of the naphthalene ring. Free radical substitution reactions can occur under the action of light or free radical initiators, such as reacting with halogen elemental substances, and halogen atoms replace the hydrogen on the methyl group. The naphthalene ring itself, due to the characteristics of electron cloud density distribution, in the electrophilic substitution reaction, the α-site activity is higher than the β-site, and it can be electrophilically substituted with halogenating agents, nitrifying agents, sulfonating agents, etc., and groups such as halogen atoms, nitro groups, and sulfonic acid groups are introduced into the naphthalene ring.
- ** Physical properties **: At room temperature, or as a solid, due to strong intermolecular forces, its melting and boiling point has a certain height. It has a certain solubility in common organic solvents such as ethanol and ether. Due to the principle of similar compatibility, its structure is compatible with organic solvents.
- ** Oxidation reaction **: The aldehyde group in the molecule is active in nature. In case of strong oxidants such as potassium permanganate, the aldehyde group can be oxidized to a carboxyl group to obtain derivatives containing carboxyl groups. If treated with mild oxidants, such as Torun reagent or Feilin reagent, the aldehyde group is also oxidized. The former produces silver mirror phenomenon, and the latter produces brick red precipitation, which is a typical oxidation reaction characteristic of aldehyde groups.
- ** Addition reaction **: The carbon and oxygen double bond in the aldehyde group has electrophilicity and can be added with a variety of nucleophiles. In case of alcohols, under acid-catalyzed conditions, acetalylation can occur to form acetal structures. This reaction is often used as a carbonyl protection method in organic synthesis. The naphthalene ring part, although aromatic and relatively stable, can also undergo electrophilic addition reaction under specific conditions, such as strong Lewis acid catalysis and high reagent activity, and new groups can be introduced into the naphthalene ring.
- ** Substitution reaction **: The methyl group is attached to the naphthalene ring, and the hydrogen atom on the methyl group has a certain activity under the influence of the naphthalene ring. Free radical substitution reactions can occur under the action of light or free radical initiators, such as reacting with halogen elemental substances, and halogen atoms replace the hydrogen on the methyl group. The naphthalene ring itself, due to the characteristics of electron cloud density distribution, in the electrophilic substitution reaction, the α-site activity is higher than the β-site, and it can be electrophilically substituted with halogenating agents, nitrifying agents, sulfonating agents, etc., and groups such as halogen atoms, nitro groups, and sulfonic acid groups are introduced into the naphthalene ring.
What are the common uses of 1-bromo-2-chloro-4-methylbenzene?
The common use of 1 + -ether-2-alkane-4-methylbenzene is indispensable in the fields of chemical industry, medicine, and materials.
In the chemical industry, these substances are often important raw materials for organic synthesis. For example, ethers have good solubility and are often used as organic solvents to assist in various organic reactions. And in the organic synthesis path, complex organic molecular structures can be constructed by specific reactions, laying the foundation for the preparation of many fine chemicals. Alkanes are also basic chemical raw materials. Like alkanes obtained from petroleum refining, key chemical intermediates such as ethylene and propylene can be obtained through cracking and reforming processes, and then polymer materials such as plastics, rubber, and fibers can be synthesized. 4-Methylbenzene plays an important role in the aromatic hydrocarbon chemical system. After a series of reactions, a variety of high value-added chemicals can be prepared.
In the field of medicine, such substances are also useful. Some ether compounds have special pharmacological activity, or can be used as pharmaceutical active ingredients, or as solvents and co-solvents in pharmaceutical preparations, etc., to improve drug solubility, stability and bioavailability. Although alkanes are often not directly used in medicine, they can be reaction mediators during drug synthesis to ensure the smooth occurrence of reactions. 4-Methylbenzene can become drug intermediates with specific pharmacological effects after modification, helping to develop new drugs.
In the field of materials, 1 + -ether-2-alkane-4-methylbenzene has also made significant contributions. For example, ether polymer materials, due to their unique physical and chemical properties, are widely used in electronics, optical materials, etc., or have excellent insulation, used for electronic component packaging; or have special optical properties, used in optical lenses, optical fibers, etc. Alkanes can participate in the synthesis of high-performance polyolefin materials, improving the mechanical properties and chemical corrosion resistance of materials. 4-Methylbenzene-related derivatives can be polymerized and other reactions to produce special engineering plastics, which can be used in high-end fields such as aerospace and automobile manufacturing to meet the demand for high-performance materials.
In the chemical industry, these substances are often important raw materials for organic synthesis. For example, ethers have good solubility and are often used as organic solvents to assist in various organic reactions. And in the organic synthesis path, complex organic molecular structures can be constructed by specific reactions, laying the foundation for the preparation of many fine chemicals. Alkanes are also basic chemical raw materials. Like alkanes obtained from petroleum refining, key chemical intermediates such as ethylene and propylene can be obtained through cracking and reforming processes, and then polymer materials such as plastics, rubber, and fibers can be synthesized. 4-Methylbenzene plays an important role in the aromatic hydrocarbon chemical system. After a series of reactions, a variety of high value-added chemicals can be prepared.
In the field of medicine, such substances are also useful. Some ether compounds have special pharmacological activity, or can be used as pharmaceutical active ingredients, or as solvents and co-solvents in pharmaceutical preparations, etc., to improve drug solubility, stability and bioavailability. Although alkanes are often not directly used in medicine, they can be reaction mediators during drug synthesis to ensure the smooth occurrence of reactions. 4-Methylbenzene can become drug intermediates with specific pharmacological effects after modification, helping to develop new drugs.
In the field of materials, 1 + -ether-2-alkane-4-methylbenzene has also made significant contributions. For example, ether polymer materials, due to their unique physical and chemical properties, are widely used in electronics, optical materials, etc., or have excellent insulation, used for electronic component packaging; or have special optical properties, used in optical lenses, optical fibers, etc. Alkanes can participate in the synthesis of high-performance polyolefin materials, improving the mechanical properties and chemical corrosion resistance of materials. 4-Methylbenzene-related derivatives can be polymerized and other reactions to produce special engineering plastics, which can be used in high-end fields such as aerospace and automobile manufacturing to meet the demand for high-performance materials.
What are the methods for synthesizing 1-bromo-2-chloro-4-methylbenzene?
To prepare 1-bromo-2-chloro-4-methylbenzene, the following ancient method can be used:
First, toluene is used as the starting material, and the method of sulfonation is used to make toluene and concentrated sulfuric acid co-heat. Because methyl is the ortho-para-position group, the sulfonic acid group is mainly introduced into the para-position of methyl to obtain p-toluenesulfonic acid. This step of the reaction uses the space-occupying property of the sulfonic acid group to pave the way for the subsequent reaction.
Times, p-toluenesulfonic acid is co-chlorinated with chlorine gas. The co-localization effect of the edge sulfonic acid group and methyl group, the chlorine atom can be precisely introduced into the ortho-position Next, 2-chloro-4-methylbenzene sulfonic acid is treated with dilute sulfuric acid to hydrolyze and remove the sulfonic acid group to obtain 2-chloro-4-methylbenzene.
Then 2-chloro-4-methylbenzene is reacted with bromine under the catalysis of an appropriate catalyst such as iron powder. At this time, because the methyl group is an ortho-site, the bromine atom is introduced into the methyl ortho-site (affected by the chlorine atom, the ortho-site with small steric resistance is more likely to react), resulting in 1-bromo-2-chloro-4-methylbenzene.
There are other methods. First, toluene is used as the starting point, and it is reacted with chlorine under light conditions. The hydrogen atom on the methyl group is replaced by the chlorine atom to obtain benzyl chloride. Benzyl chloride and sodium bromide undergo a halogen exchange reaction in an appropriate solvent, and some chlorine atoms are replaced by bromine atoms to obtain benzyl bromide. Subsequently, benzyl bromide undergoes a Fu-gram alkylation reaction with chlorobenzene under the catalysis of Lewis acid such as aluminum trichloride. By controlling the reaction conditions and the proportion of raw materials, benzyl can be mainly introduced into the ortho-position of the chlorine atom in chlorobenzene (because the chlorine atom is an ortho-position group, and the ortho-position product is mainly caused by the steric resistance factor), However, the steps of this method are slightly complicated, and involve the preparation and reaction of halogenated hydrocarbons, which requires higher control of conditions.
First, toluene is used as the starting material, and the method of sulfonation is used to make toluene and concentrated sulfuric acid co-heat. Because methyl is the ortho-para-position group, the sulfonic acid group is mainly introduced into the para-position of methyl to obtain p-toluenesulfonic acid. This step of the reaction uses the space-occupying property of the sulfonic acid group to pave the way for the subsequent reaction.
Times, p-toluenesulfonic acid is co-chlorinated with chlorine gas. The co-localization effect of the edge sulfonic acid group and methyl group, the chlorine atom can be precisely introduced into the ortho-position Next, 2-chloro-4-methylbenzene sulfonic acid is treated with dilute sulfuric acid to hydrolyze and remove the sulfonic acid group to obtain 2-chloro-4-methylbenzene.
Then 2-chloro-4-methylbenzene is reacted with bromine under the catalysis of an appropriate catalyst such as iron powder. At this time, because the methyl group is an ortho-site, the bromine atom is introduced into the methyl ortho-site (affected by the chlorine atom, the ortho-site with small steric resistance is more likely to react), resulting in 1-bromo-2-chloro-4-methylbenzene.
There are other methods. First, toluene is used as the starting point, and it is reacted with chlorine under light conditions. The hydrogen atom on the methyl group is replaced by the chlorine atom to obtain benzyl chloride. Benzyl chloride and sodium bromide undergo a halogen exchange reaction in an appropriate solvent, and some chlorine atoms are replaced by bromine atoms to obtain benzyl bromide. Subsequently, benzyl bromide undergoes a Fu-gram alkylation reaction with chlorobenzene under the catalysis of Lewis acid such as aluminum trichloride. By controlling the reaction conditions and the proportion of raw materials, benzyl can be mainly introduced into the ortho-position of the chlorine atom in chlorobenzene (because the chlorine atom is an ortho-position group, and the ortho-position product is mainly caused by the steric resistance factor), However, the steps of this method are slightly complicated, and involve the preparation and reaction of halogenated hydrocarbons, which requires higher control of conditions.
What are the precautions for storing and transporting 1-bromo-2-chloro-4-methylbenzene?
1 + - + ether + - + 2 + - + alkane + - + 4 + - + methylbenzene During storage and transportation, the following things should be paid attention to:
First, the location is very important. The storage place must be cool, ventilated, and away from fire and heat sources. Because ethers, alkanes, and methylbenzene are flammable, they can easily cause the risk of combustion or even explosion under high temperature or open flame environment. And the warehouse temperature should not be too high, usually within a specific range to prevent the substance from evaporating due to excessive temperature or other dangerous changes.
Second, the packaging must be tight. The packaging materials used must be able to effectively prevent leakage and avoid contact between such substances and the external environment. Because they are volatile and irritating, once leaked, not only will cause pollution to the environment, but also may endanger human health. Like methyl benzene, its volatile gases can irritate the respiratory tract and eyes.
Third, when transporting, it is necessary to strictly follow the regulations. Transportation vehicles need to be equipped with corresponding fire equipment and leakage emergency treatment equipment. During transportation, it is necessary to ensure that the container does not tip, leak or damage. At the same time, drivers and escorts need to be familiar with the characteristics of the substances contained and emergency treatment methods to deal with emergencies.
Fourth, isolated storage should not be ignored. 1-Ether-2-alkane-4-methylbenzene should not be mixed with oxidants, acids, etc. Due to contact with these substances, violent chemical reactions may occur, posing serious dangers.
Fifth, the logo should be clear and clear. Whether it is a storage container or a transportation vehicle, a prominent dangerous chemical label should be posted, indicating the name of the substance, dangerous characteristics and other information, so that relevant personnel can identify and prevent. In this way, the process of storing and transporting 1-ether-2-alkane-4-methylbenzene can ensure safety to the greatest extent and reduce the possibility of accidents.
First, the location is very important. The storage place must be cool, ventilated, and away from fire and heat sources. Because ethers, alkanes, and methylbenzene are flammable, they can easily cause the risk of combustion or even explosion under high temperature or open flame environment. And the warehouse temperature should not be too high, usually within a specific range to prevent the substance from evaporating due to excessive temperature or other dangerous changes.
Second, the packaging must be tight. The packaging materials used must be able to effectively prevent leakage and avoid contact between such substances and the external environment. Because they are volatile and irritating, once leaked, not only will cause pollution to the environment, but also may endanger human health. Like methyl benzene, its volatile gases can irritate the respiratory tract and eyes.
Third, when transporting, it is necessary to strictly follow the regulations. Transportation vehicles need to be equipped with corresponding fire equipment and leakage emergency treatment equipment. During transportation, it is necessary to ensure that the container does not tip, leak or damage. At the same time, drivers and escorts need to be familiar with the characteristics of the substances contained and emergency treatment methods to deal with emergencies.
Fourth, isolated storage should not be ignored. 1-Ether-2-alkane-4-methylbenzene should not be mixed with oxidants, acids, etc. Due to contact with these substances, violent chemical reactions may occur, posing serious dangers.
Fifth, the logo should be clear and clear. Whether it is a storage container or a transportation vehicle, a prominent dangerous chemical label should be posted, indicating the name of the substance, dangerous characteristics and other information, so that relevant personnel can identify and prevent. In this way, the process of storing and transporting 1-ether-2-alkane-4-methylbenzene can ensure safety to the greatest extent and reduce the possibility of accidents.
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