Linshang Chemical
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1-Bromo-2-Chloro-5-Nitrobenzene
Linshang Chemical
|
HS Code |
828499 |
| Chemical Formula | C6H3BrClNO2 |
| Molecular Weight | 252.45 |
| Appearance | Solid (usually) |
| Melting Point | Data needed |
| Boiling Point | Data needed |
| Solubility In Water | Low (expected, due to non - polar nature) |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Density | Data needed |
| Flash Point | Data needed |
| Hazard Class | Irritant (may cause skin, eye and respiratory irritation) |
As an accredited 1-Bromo-2-Chloro-5-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - bromo - 2 - chloro - 5 - nitrobenzene in 100 - gram sealed glass bottles for safe storage. |
| Storage | 1 - Bromo - 2 - chloro - 5 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents, reducing agents, and reactive metals due to potential chemical reactions. Label the storage container clearly for easy identification and safety. |
| Shipping | 1 - bromo - 2 - chloro - 5 - nitrobenzene is shipped in well - sealed containers, often within a climate - controlled environment. Precautions are taken to prevent breakage and exposure, as it's a chemical with potential hazards during transit. |
Competitive 1-Bromo-2-Chloro-5-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Bromo-2-Chloro-5-Nitrobenzene in China?
As a trusted 1-Bromo-2-Chloro-5-Nitrobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Bromo-2-Chloro-5-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 1 - bromo - 2 - chloro - 5 - nitrobenzene
1-Bromo-2-chloro-5-nitrobenzene is one of the organic compounds. Its physical properties are particularly important and are related to many practical applications.
In terms of its appearance, 1-bromo-2-chloro-5-nitrobenzene is generally a light yellow to light brown crystalline powder. This appearance feature can be visually identified by the naked eye, and is quite useful for the preliminary identification and identification of substances.
When it comes to the melting point, its melting point is within a certain range, which is extremely critical when identifying the compound. The determination of the melting point can help determine the purity of the substance. If the purity of the substance is high, the melting point range is relatively narrow; if it contains impurities, the melting point may be offset and the range will become wider.
The boiling point is also one of the important physical properties. The boiling point of 1-bromo-2-chloro-5-nitrobenzene is specific. Under specific pressure conditions, the temperature at which the substance changes from liquid to gaseous state is fixed. Knowing the boiling point is of great significance in the process of separating and purifying the compound, and suitable distillation conditions can be selected accordingly.
Furthermore, the solubility cannot be ignored. 1-Bromo-2-chloro-5-nitrobenzene has a certain solubility in organic solvents such as ethanol and ether, but its solubility in water is very small. This difference in solubility can be used to select suitable solvents for recrystallization, extraction and other operations to achieve purification and separation of substances.
In addition, density is also one of its physical properties. 1-bromo-2-chloro-5-nitrobenzene has a specific density, which is of reference value in chemical production, quality control, etc. By measuring the density, it can assist in judging the purity of the substance and whether it is mixed with other impurities.
In conclusion, the physical properties of 1-bromo-2-chloro-5-nitrobenzene, such as appearance, melting point, boiling point, solubility and density, are the basis for in-depth understanding of the compound, and its synthesis, separation, purification and application play an indispensable role.
In terms of its appearance, 1-bromo-2-chloro-5-nitrobenzene is generally a light yellow to light brown crystalline powder. This appearance feature can be visually identified by the naked eye, and is quite useful for the preliminary identification and identification of substances.
When it comes to the melting point, its melting point is within a certain range, which is extremely critical when identifying the compound. The determination of the melting point can help determine the purity of the substance. If the purity of the substance is high, the melting point range is relatively narrow; if it contains impurities, the melting point may be offset and the range will become wider.
The boiling point is also one of the important physical properties. The boiling point of 1-bromo-2-chloro-5-nitrobenzene is specific. Under specific pressure conditions, the temperature at which the substance changes from liquid to gaseous state is fixed. Knowing the boiling point is of great significance in the process of separating and purifying the compound, and suitable distillation conditions can be selected accordingly.
Furthermore, the solubility cannot be ignored. 1-Bromo-2-chloro-5-nitrobenzene has a certain solubility in organic solvents such as ethanol and ether, but its solubility in water is very small. This difference in solubility can be used to select suitable solvents for recrystallization, extraction and other operations to achieve purification and separation of substances.
In addition, density is also one of its physical properties. 1-bromo-2-chloro-5-nitrobenzene has a specific density, which is of reference value in chemical production, quality control, etc. By measuring the density, it can assist in judging the purity of the substance and whether it is mixed with other impurities.
In conclusion, the physical properties of 1-bromo-2-chloro-5-nitrobenzene, such as appearance, melting point, boiling point, solubility and density, are the basis for in-depth understanding of the compound, and its synthesis, separation, purification and application play an indispensable role.
Chemical properties of 1 - bromo - 2 - chloro - 5 - nitrobenzene
The chemical properties of 1 + -bromo-2-chloro-5-nitrobenzene are particularly important and are involved in the field of organic chemistry. In this compound, bromine (Br), chlorine (Cl) and nitro ($NO_2 $) are all important functional groups, and each functional group endows it with unique properties.
Nitro is a strong electron-absorbing group, which can reduce the electron cloud density of the benzene ring and weaken the electrophilic substitution activity of the benzene ring. And due to the existence of nitro groups, this compound can undergo reduction reaction under specific conditions, and nitro groups can be converted into amino groups ($NH_2 $). This is an important transition in organic synthesis, which can be used to prepare derivatives containing amino groups. It has a wide range of uses in drug synthesis, dye preparation and other fields.
Although bromine and chlorine are both halogen atoms, their activities are slightly different. The halogen atom on the benzene ring is an ortho-para-site localization group, which can make the electrophilic substitution reaction of the benzene ring mainly occur in the ortho-site and the para-site. However, due to the strong electron absorption of nitro groups, the ortho-site is greatly affected by it, so the para-site products may be more common in the electrophilic substitution reaction. At the same time, halogen atoms can undergo nucleophilic substitution reactions, and bromine or chlorine can be replaced by other groups under appropriate nucleophilic reagents and reaction conditions. In the case of strong nucleophilic reagents, bromine atoms are more likely to leave than chlorine atoms. Due to the large atomic radius of bromine, the bond energy of $C-Br $is relatively small, which is more conducive to the attack of nucleophilic reagents. This difference needs to be taken into account in the design of organic synthesis routes.
In addition, 1-bromo-2-chloro-5-nitrobenzene may also participate in some rearrangement reactions involving benzene rings, cyclization reactions, etc., depending on the specific reaction conditions and the added reagents. In organic synthetic chemistry, it is an important intermediate that can be used to construct more complex organic compounds through various reactions, and plays a key role in many industrial production and scientific research.
Nitro is a strong electron-absorbing group, which can reduce the electron cloud density of the benzene ring and weaken the electrophilic substitution activity of the benzene ring. And due to the existence of nitro groups, this compound can undergo reduction reaction under specific conditions, and nitro groups can be converted into amino groups ($NH_2 $). This is an important transition in organic synthesis, which can be used to prepare derivatives containing amino groups. It has a wide range of uses in drug synthesis, dye preparation and other fields.
Although bromine and chlorine are both halogen atoms, their activities are slightly different. The halogen atom on the benzene ring is an ortho-para-site localization group, which can make the electrophilic substitution reaction of the benzene ring mainly occur in the ortho-site and the para-site. However, due to the strong electron absorption of nitro groups, the ortho-site is greatly affected by it, so the para-site products may be more common in the electrophilic substitution reaction. At the same time, halogen atoms can undergo nucleophilic substitution reactions, and bromine or chlorine can be replaced by other groups under appropriate nucleophilic reagents and reaction conditions. In the case of strong nucleophilic reagents, bromine atoms are more likely to leave than chlorine atoms. Due to the large atomic radius of bromine, the bond energy of $C-Br $is relatively small, which is more conducive to the attack of nucleophilic reagents. This difference needs to be taken into account in the design of organic synthesis routes.
In addition, 1-bromo-2-chloro-5-nitrobenzene may also participate in some rearrangement reactions involving benzene rings, cyclization reactions, etc., depending on the specific reaction conditions and the added reagents. In organic synthetic chemistry, it is an important intermediate that can be used to construct more complex organic compounds through various reactions, and plays a key role in many industrial production and scientific research.
What is the main use of 1 - bromo - 2 - chloro - 5 - nitrobenzene
1-Bromo-2-chloro-5-nitrobenzene is also an organic compound. Its main uses are wide.
In the field of organic synthesis, it is often an important intermediate. In its structure, bromine, chlorine, and nitro groups all have unique chemical activities. Bromine and chlorine atoms can be substituted by nucleophilic substitution, and react with many nucleophilic reagents to introduce other functional groups to build a multi-component organic molecular structure. For example, when reacted with alkoxides, corresponding ether compounds can be formed; when reacted with amines, nitrogen-containing derivatives can be obtained.
The presence of nitro groups also affects the reactivity of molecules. Nitro groups can be reduced to amino groups, which can provide active checking points for further reactions, such as participating in amidation reactions, etc., which are of key significance in the process of preparing fine chemicals such as drugs and dyes.
In materials science, compounds synthesized from this raw material may have special electrical and optical properties. Due to the synergistic action of different functional groups in molecules, they can be applied to the creation of organic semiconductor materials, photochromic materials, etc., which contribute to the development of the materials field.
In the field of pharmaceutical chemistry, it may be a potential drug lead compound. By modifying and modifying its structure, new drugs may be developed for the treatment of various diseases. Due to its unique chemical structure, it may interact with specific targets in organisms, exhibiting pharmacological activity.
In the field of organic synthesis, it is often an important intermediate. In its structure, bromine, chlorine, and nitro groups all have unique chemical activities. Bromine and chlorine atoms can be substituted by nucleophilic substitution, and react with many nucleophilic reagents to introduce other functional groups to build a multi-component organic molecular structure. For example, when reacted with alkoxides, corresponding ether compounds can be formed; when reacted with amines, nitrogen-containing derivatives can be obtained.
The presence of nitro groups also affects the reactivity of molecules. Nitro groups can be reduced to amino groups, which can provide active checking points for further reactions, such as participating in amidation reactions, etc., which are of key significance in the process of preparing fine chemicals such as drugs and dyes.
In materials science, compounds synthesized from this raw material may have special electrical and optical properties. Due to the synergistic action of different functional groups in molecules, they can be applied to the creation of organic semiconductor materials, photochromic materials, etc., which contribute to the development of the materials field.
In the field of pharmaceutical chemistry, it may be a potential drug lead compound. By modifying and modifying its structure, new drugs may be developed for the treatment of various diseases. Due to its unique chemical structure, it may interact with specific targets in organisms, exhibiting pharmacological activity.
What are the synthesis methods of 1 - bromo - 2 - chloro - 5 - nitrobenzene
There are several methods for synthesizing 1 + -bromo-2 + -chloro-5 + -nitrobenzene.
First, halogenated aromatics are used as starting materials. First, halogenated benzene is taken, and the nitro group is introduced into the benzene ring through nitration reaction. This reaction requires a mixed acid of concentrated nitric acid and concentrated sulfuric acid. Control the appropriate temperature, and the nitro group will selectively enter the specific position of the benzene ring. Then, the halogenation reaction is carried out. If the starting point is chlorobenzene, bromine atoms can be introduced through bromination reaction; if the starting point is bromobenzene, chlorine atoms can be introduced through chlorination reaction. This process requires specific halogenation reagents and catalysts, such as liquid bromine and iron powder can be used during bromination, and chlorine gas and ferric chloride can be used
Second, nitrobenzene is used as the starting material. First, nitrobenzene is halogenated, and bromine and chlorine atoms are introduced. Since the nitro group is a strong electron-absorbing group, the positioning effect of the halogenation reaction makes the halogen atoms mainly enter the position between the nitro groups. By choosing the appropriate halogenation sequence and conditions, the synthesis of 1 + -bromo-2 + -chloro-5 + -nitrobenzene can be realized. If brominated and then chlorinated, or vice versa, the choice needs to be made according to the specific reaction conditions and yield requirements.
Third, benzene is used as the starting material and synthesized through a multi-step reaction. First, the benzene is nitrified, and the nitro group is introduced. After that, the bromination and chlorination reactions are carried out in sequence. There In each step of the reaction, it is necessary to precisely control the reaction conditions, such as temperature, reagent dosage, catalyst type, etc., to ensure that the reaction proceeds in the desired direction and improve the yield and purity of the target product.
These three methods have their own advantages and disadvantages. In actual synthesis, it is necessary to comprehensively consider factors such as raw material cost, ease of control of reaction conditions, yield and product purity to choose the optimal synthesis path.
First, halogenated aromatics are used as starting materials. First, halogenated benzene is taken, and the nitro group is introduced into the benzene ring through nitration reaction. This reaction requires a mixed acid of concentrated nitric acid and concentrated sulfuric acid. Control the appropriate temperature, and the nitro group will selectively enter the specific position of the benzene ring. Then, the halogenation reaction is carried out. If the starting point is chlorobenzene, bromine atoms can be introduced through bromination reaction; if the starting point is bromobenzene, chlorine atoms can be introduced through chlorination reaction. This process requires specific halogenation reagents and catalysts, such as liquid bromine and iron powder can be used during bromination, and chlorine gas and ferric chloride can be used
Second, nitrobenzene is used as the starting material. First, nitrobenzene is halogenated, and bromine and chlorine atoms are introduced. Since the nitro group is a strong electron-absorbing group, the positioning effect of the halogenation reaction makes the halogen atoms mainly enter the position between the nitro groups. By choosing the appropriate halogenation sequence and conditions, the synthesis of 1 + -bromo-2 + -chloro-5 + -nitrobenzene can be realized. If brominated and then chlorinated, or vice versa, the choice needs to be made according to the specific reaction conditions and yield requirements.
Third, benzene is used as the starting material and synthesized through a multi-step reaction. First, the benzene is nitrified, and the nitro group is introduced. After that, the bromination and chlorination reactions are carried out in sequence. There In each step of the reaction, it is necessary to precisely control the reaction conditions, such as temperature, reagent dosage, catalyst type, etc., to ensure that the reaction proceeds in the desired direction and improve the yield and purity of the target product.
These three methods have their own advantages and disadvantages. In actual synthesis, it is necessary to comprehensively consider factors such as raw material cost, ease of control of reaction conditions, yield and product purity to choose the optimal synthesis path.
1 - bromo - 2 - chloro - 5 - nitrobenzene in storage and transport
1 + -Bromo-2-chloro-5-nitrobenzene is also an organic compound. During storage and transportation, many matters must not be ignored.
First words storage. This material is active, toxic and corrosive, and should be stored in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent accidents. Because of its flammability and easy to react with oxidants, it must be stored separately from oxidants, reducing agents, alkalis, etc., and must not be mixed to avoid danger. Storage containers must also be carefully selected, and must be made of corrosion-resistant materials to prevent leakage. Check the integrity of the container regularly. If there is any damage, deal with it immediately.
As for transportation, there are also many points to pay attention to. Transportation vehicles must be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. In summer transportation, it is advisable to choose morning and evening hours to avoid high temperature and hot sun. During transportation, make sure that the container is not tilted, leaked or damaged. The speed of the vehicle should not be too fast, and it should not be braked suddenly to prevent damage to the container due to vibration or impact. When loading and unloading, the operation must be cautious, and the packaging should be handled lightly to avoid damage. Transport personnel should also be familiar with the characteristics of this object and emergency disposal methods to prepare for emergencies.
In conclusion, the storage and transportation of 1 + -bromo-2-chloro-5-nitrobenzene must be treated with caution and relevant procedures must be strictly followed to ensure safety.
First words storage. This material is active, toxic and corrosive, and should be stored in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent accidents. Because of its flammability and easy to react with oxidants, it must be stored separately from oxidants, reducing agents, alkalis, etc., and must not be mixed to avoid danger. Storage containers must also be carefully selected, and must be made of corrosion-resistant materials to prevent leakage. Check the integrity of the container regularly. If there is any damage, deal with it immediately.
As for transportation, there are also many points to pay attention to. Transportation vehicles must be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. In summer transportation, it is advisable to choose morning and evening hours to avoid high temperature and hot sun. During transportation, make sure that the container is not tilted, leaked or damaged. The speed of the vehicle should not be too fast, and it should not be braked suddenly to prevent damage to the container due to vibration or impact. When loading and unloading, the operation must be cautious, and the packaging should be handled lightly to avoid damage. Transport personnel should also be familiar with the characteristics of this object and emergency disposal methods to prepare for emergencies.
In conclusion, the storage and transportation of 1 + -bromo-2-chloro-5-nitrobenzene must be treated with caution and relevant procedures must be strictly followed to ensure safety.
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