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1-Bromo-3-Chloro-2,4,5-Trifluorobenzene
|
HS Code |
858584 |
| Chemical Formula | C6HBrClF3 |
| Molecular Weight | 259.42 |
| Appearance | Liquid (usually) |
| Density | Data needed |
| Boiling Point | Data needed |
| Melting Point | Data needed |
| Solubility In Water | Low (organic compound, likely hydrophobic) |
| Solubility In Organic Solvents | Good solubility in common organic solvents |
| Flash Point | Data needed |
| Vapor Pressure | Data needed |
| Odor | Typical halogenated aromatic odor (likely) |
| Stability | Stable under normal conditions, but reactive with strong bases/oxidizing agents |
As an accredited 1-Bromo-3-Chloro-2,4,5-Trifluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 mL bottle containing 1 - bromo - 3 - chloro - 2,4,5 - trifluorobenzene. |
| Storage | 1 - bromo - 3 - chloro - 2,4,5 - trifluorobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive chemicals to avoid potential chemical reactions. |
| Shipping | 1 - bromo - 3 - chloro - 2,4,5 - trifluorobenzene is a chemical. It should be shipped in well - sealed, corrosion - resistant containers, following all relevant hazardous materials regulations to ensure safe transportation. |
Competitive 1-Bromo-3-Chloro-2,4,5-Trifluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to sales01@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: sales01@alchemist-chem.com
Where to Buy 1-Bromo-3-Chloro-2,4,5-Trifluorobenzene in China?
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Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Bromo-3-Chloro-2,4,5-Trifluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1-bromo-3-chloro-2,4,5-trifluorobenzene?
1-Bromo-3-chloro-2,4,5-trifluorobenzene is an important organic compound with a wide range of uses in organic synthesis and other fields. Its main uses are as follows:
First, in the field of pharmaceutical chemistry, this compound is often used as a key intermediate. The complex molecular structure of 1-bromo-3-chloro-2,4,5-trifluorobenzene is often required to construct a complex molecular structure. The halogen atoms of 1-bromo-3-chloro-2,4,5-trifluorobenzene can be introduced into other specific functional groups through various organic reactions, such as nucleophilic substitution reactions, to build a biologically active drug molecular skeleton. Through such reactions, chemists can precisely regulate the molecular structure to develop effective drugs for specific diseases.
Second, it is also of great value in the field of materials science. For example, in the preparation of organic optoelectronic materials, the compound can be used to participate in polymerization or other film-forming reactions, and with its unique chemical structure and electronic properties, the photoelectric properties of the material can be improved, such as improving the conductivity and fluorescence efficiency of the material. In this way, organic Light Emitting Diode (OLED) materials and solar cell materials with better performance can be prepared to promote the development of materials science.
Third, in the field of pesticide chemistry, 1-bromo-3-chloro-2,4,5-trifluorobenzene is also used. Through appropriate chemical modification, it can be converted into pesticide components with insecticidal, bactericidal or herbicidal activities. Due to its special structure, pesticides may have higher biological activity and selectivity, which can ensure agricultural production while reducing adverse effects on the environment.
In short, 1-bromo-3-chloro-2,4,5-trifluorobenzene, as an important organic synthesis intermediate, plays an indispensable role in many fields such as medicine, materials, and pesticides, and is of great significance to promote technological progress and industrial development in related fields.
First, in the field of pharmaceutical chemistry, this compound is often used as a key intermediate. The complex molecular structure of 1-bromo-3-chloro-2,4,5-trifluorobenzene is often required to construct a complex molecular structure. The halogen atoms of 1-bromo-3-chloro-2,4,5-trifluorobenzene can be introduced into other specific functional groups through various organic reactions, such as nucleophilic substitution reactions, to build a biologically active drug molecular skeleton. Through such reactions, chemists can precisely regulate the molecular structure to develop effective drugs for specific diseases.
Second, it is also of great value in the field of materials science. For example, in the preparation of organic optoelectronic materials, the compound can be used to participate in polymerization or other film-forming reactions, and with its unique chemical structure and electronic properties, the photoelectric properties of the material can be improved, such as improving the conductivity and fluorescence efficiency of the material. In this way, organic Light Emitting Diode (OLED) materials and solar cell materials with better performance can be prepared to promote the development of materials science.
Third, in the field of pesticide chemistry, 1-bromo-3-chloro-2,4,5-trifluorobenzene is also used. Through appropriate chemical modification, it can be converted into pesticide components with insecticidal, bactericidal or herbicidal activities. Due to its special structure, pesticides may have higher biological activity and selectivity, which can ensure agricultural production while reducing adverse effects on the environment.
In short, 1-bromo-3-chloro-2,4,5-trifluorobenzene, as an important organic synthesis intermediate, plays an indispensable role in many fields such as medicine, materials, and pesticides, and is of great significance to promote technological progress and industrial development in related fields.
What are the physical properties of 1-bromo-3-chloro-2,4,5-trifluorobenzene
1-Bromo-3-chloro-2,4,5-trifluorobenzene is an organic compound with special physical properties. Its properties are usually colorless to light yellow liquids, which exist stably at room temperature and pressure.
Looking at its appearance, it is often in the state of a clear liquid, light in color, or colorless, or slightly yellowish. This color characteristic is easy to observe and identify in many reactions and applications.
Smell, has a unique odor, but the specific description of the relevant odor is not yet detailed in the existing data.
When it comes to melting point and boiling point, the melting point is not yet clearly documented, and the boiling point is about 186-187 ° C. Boiling point This value indicates that it changes from liquid to gaseous at a specific temperature. This property is crucial in chemical operations such as distillation and separation. Practitioners can choose appropriate temperature conditions accordingly to achieve effective separation of the compound from other substances.
In terms of density, it is about 1.832 g/mL. This density data is of great significance in chemical production and experimental operations. For example, when preparing mixed solutions, the proportions of each component can be reasonably adjusted according to the density difference to ensure that the reaction system is uniform and stable.
In terms of solubility, it is slightly soluble in water, but soluble in common organic solvents such as ethanol, ether, acetone, etc. This solubility characteristic determines its application in organic synthesis. In organic solvents, it can participate in various reactions more efficiently, providing a basis for the design of organic synthesis routes.
In addition, although the physical properties such as vapor pressure and flash point of 1-bromo-3-chloro-2,4,5-trifluorobenzene are not available, it is speculated that its vapor pressure is low, flash point or relatively high, because its molecular structure contains halogen atoms, which enhances the stability of the compound and reduces the volatility. This speculation is of great significance for the safety of its storage and transportation. When storing, it is necessary to consider the characteristics of low vapor pressure, choose a well-sealed container, and prevent leakage. In view of the possible high flash point during transportation, it can be operated according to the transportation requirements of ordinary chemicals, and at the same time pay attention to its potential reaction risks with other substances.
Looking at its appearance, it is often in the state of a clear liquid, light in color, or colorless, or slightly yellowish. This color characteristic is easy to observe and identify in many reactions and applications.
Smell, has a unique odor, but the specific description of the relevant odor is not yet detailed in the existing data.
When it comes to melting point and boiling point, the melting point is not yet clearly documented, and the boiling point is about 186-187 ° C. Boiling point This value indicates that it changes from liquid to gaseous at a specific temperature. This property is crucial in chemical operations such as distillation and separation. Practitioners can choose appropriate temperature conditions accordingly to achieve effective separation of the compound from other substances.
In terms of density, it is about 1.832 g/mL. This density data is of great significance in chemical production and experimental operations. For example, when preparing mixed solutions, the proportions of each component can be reasonably adjusted according to the density difference to ensure that the reaction system is uniform and stable.
In terms of solubility, it is slightly soluble in water, but soluble in common organic solvents such as ethanol, ether, acetone, etc. This solubility characteristic determines its application in organic synthesis. In organic solvents, it can participate in various reactions more efficiently, providing a basis for the design of organic synthesis routes.
In addition, although the physical properties such as vapor pressure and flash point of 1-bromo-3-chloro-2,4,5-trifluorobenzene are not available, it is speculated that its vapor pressure is low, flash point or relatively high, because its molecular structure contains halogen atoms, which enhances the stability of the compound and reduces the volatility. This speculation is of great significance for the safety of its storage and transportation. When storing, it is necessary to consider the characteristics of low vapor pressure, choose a well-sealed container, and prevent leakage. In view of the possible high flash point during transportation, it can be operated according to the transportation requirements of ordinary chemicals, and at the same time pay attention to its potential reaction risks with other substances.
What are the synthesis methods of 1-bromo-3-chloro-2,4,5-trifluorobenzene?
1-Bromo-3-chloro-2,4,5-trifluorobenzene is an important organic compound. There are many synthesis methods for it, which are described in ancient methods.
First, it can be obtained by the gradual substitution reaction of polyhalogenated benzene. First, take a benzene derivative containing an appropriate halogen atom, and use a specific nucleophilic reagent to replace the halogen atom in sequence at a suitable temperature and solvent conditions. For example, using a benzene halide containing chlorine and fluorine as the starting material, under the catalysis of a base, react with a brominating reagent to promote the replacement of the halogen atom at a specific position by the bromine atom. In this process, the choice of solvent is very critical, such as polar aprotic solvents, which can improve the reaction rate and selectivity. Temperature also needs to be precisely controlled, too high or too low may affect the yield and purity of the product.
Second, synthesized by aromatic electrophilic substitution reaction. Using benzene as the starting material, halogen atoms are first introduced, and by controlling the reaction conditions and reagent dosage, halogen atoms are replaced in the expected position on the benzene ring. For example, chlorobenzene is first reacted with benzene with chlorinated reagents, and then bromine and fluorine atoms are introduced in sequence through bromination, fluorination and other steps. During this period, the choice and dosage of catalysts have a great impact on the reaction process. The commonly used Lewis acid catalyst can effectively promote the electrophilic substitution reaction.
Third, the cross-coupling reaction using metal catalysis. Benzene derivatives containing halogen atoms and corresponding halogenated hydrocarbons or metal-organic reagents are selected to realize the coupling of carbon-halogen bonds under the catalysis of metal catalysts such as palladium and nickel to construct the target compound. Such reaction conditions are relatively mild and highly selective. However, the cost of metal catalysts is high, and attention should be paid to the problem of metal residues after reaction.
When synthesizing 1-bromo-3-chloro-2,4,5-trifluorobenzene, no matter what method is used, the reaction conditions need to be carefully regulated, and the intermediates and products need to be strictly separated and purified to obtain high-purity target products.
First, it can be obtained by the gradual substitution reaction of polyhalogenated benzene. First, take a benzene derivative containing an appropriate halogen atom, and use a specific nucleophilic reagent to replace the halogen atom in sequence at a suitable temperature and solvent conditions. For example, using a benzene halide containing chlorine and fluorine as the starting material, under the catalysis of a base, react with a brominating reagent to promote the replacement of the halogen atom at a specific position by the bromine atom. In this process, the choice of solvent is very critical, such as polar aprotic solvents, which can improve the reaction rate and selectivity. Temperature also needs to be precisely controlled, too high or too low may affect the yield and purity of the product.
Second, synthesized by aromatic electrophilic substitution reaction. Using benzene as the starting material, halogen atoms are first introduced, and by controlling the reaction conditions and reagent dosage, halogen atoms are replaced in the expected position on the benzene ring. For example, chlorobenzene is first reacted with benzene with chlorinated reagents, and then bromine and fluorine atoms are introduced in sequence through bromination, fluorination and other steps. During this period, the choice and dosage of catalysts have a great impact on the reaction process. The commonly used Lewis acid catalyst can effectively promote the electrophilic substitution reaction.
Third, the cross-coupling reaction using metal catalysis. Benzene derivatives containing halogen atoms and corresponding halogenated hydrocarbons or metal-organic reagents are selected to realize the coupling of carbon-halogen bonds under the catalysis of metal catalysts such as palladium and nickel to construct the target compound. Such reaction conditions are relatively mild and highly selective. However, the cost of metal catalysts is high, and attention should be paid to the problem of metal residues after reaction.
When synthesizing 1-bromo-3-chloro-2,4,5-trifluorobenzene, no matter what method is used, the reaction conditions need to be carefully regulated, and the intermediates and products need to be strictly separated and purified to obtain high-purity target products.
What should be paid attention to when storing 1-bromo-3-chloro-2,4,5-trifluorobenzene?
1-Bromo-3-chloro-2,4,5-trifluorobenzene is a halogenated aromatic hydrocarbon. The following points should be paid attention to when storing:
First, because of its chemical activity, it should be stored in a cool, dry and well-ventilated place. High temperature or humid environment can easily trigger chemical reactions and cause material to deteriorate. For example, moisture in humid air may react with halogen atoms in the substance, affecting its purity.
Second, keep away from sources of ignition and oxidants. Halogenated aromatics are non-flammable, but when exposed to strong oxidants, they may react violently or even explode. Strong oxidants such as common potassium permanganate must be isolated.
Third, the storage container should be made of corrosion-resistant materials, such as glass or specific plastic materials. Because it contains halogen atoms, it is corrosive to some metals. If stored in a metal container, it may corrode the container and contaminate the substance at the same time.
Fourth, there should be a clear warning sign at the storage place to inform others that this is a chemical dangerous substance, and non-professionals should not approach it. And it is necessary to strictly control the entry and exit of personnel in the storage area to prevent unrelated personnel from accidentally touching and causing danger.
Fifth, regularly check the storage situation to see if the container is damaged or leaking. Once a leak is found, measures should be taken to deal with it in time to avoid polluting the environment and causing safety accidents. When dealing with leaks, it is necessary to use appropriate methods, such as absorbing with inert materials such as sand, according to their chemical properties, and then proceed with subsequent treatment.
First, because of its chemical activity, it should be stored in a cool, dry and well-ventilated place. High temperature or humid environment can easily trigger chemical reactions and cause material to deteriorate. For example, moisture in humid air may react with halogen atoms in the substance, affecting its purity.
Second, keep away from sources of ignition and oxidants. Halogenated aromatics are non-flammable, but when exposed to strong oxidants, they may react violently or even explode. Strong oxidants such as common potassium permanganate must be isolated.
Third, the storage container should be made of corrosion-resistant materials, such as glass or specific plastic materials. Because it contains halogen atoms, it is corrosive to some metals. If stored in a metal container, it may corrode the container and contaminate the substance at the same time.
Fourth, there should be a clear warning sign at the storage place to inform others that this is a chemical dangerous substance, and non-professionals should not approach it. And it is necessary to strictly control the entry and exit of personnel in the storage area to prevent unrelated personnel from accidentally touching and causing danger.
Fifth, regularly check the storage situation to see if the container is damaged or leaking. Once a leak is found, measures should be taken to deal with it in time to avoid polluting the environment and causing safety accidents. When dealing with leaks, it is necessary to use appropriate methods, such as absorbing with inert materials such as sand, according to their chemical properties, and then proceed with subsequent treatment.
What is the market price of 1-bromo-3-chloro-2,4,5-trifluorobenzene?
1-Bromo-3-chloro-2,4,5-trifluorobenzene is a bromotrichloro-tetrafluorobenzene, which is an important organic synthesis intermediate in the field of fine chemicals. It is widely used in medicine, pesticides, materials and many other industries. Its market price often fluctuates due to many factors such as quality, purity, supply and demand, preparation process and market competition.
Looking at the past market, if the purity is ordinary, about 95%, the batch is small, and the price per gram may be in the tens of yuan. However, due to the presence of a variety of halogen atoms, the synthesis steps are complicated, multi-step reactions are required, and the conditions are harsh. The cost of raw materials is also high, resulting in the preparation cost is not low. If the purity requirements are strict, reaching more than 99%, used in high-end pharmaceutical research and development and other fields, the price will rise sharply, or more than 100 yuan per gram.
Furthermore, the following pairs of market supply and demand have a significant impact on the price. If the pharmaceutical industry's new drug research and development has a large increase in demand for compounds containing this structure, but the supply is limited, the price will rise. On the contrary, if the number of production enterprises increases, the supply is sufficient and the demand is stable, the price may be under downward pressure. Coupled with differences in economic levels and logistics costs in different regions, the price will also vary.
To sum up, the market price of 1 - bromo - 3 - chloro - 2,4,5 - trifluorobenzene is difficult to have a fixed value, and it needs to be comprehensively determined according to the actual market conditions.
Looking at the past market, if the purity is ordinary, about 95%, the batch is small, and the price per gram may be in the tens of yuan. However, due to the presence of a variety of halogen atoms, the synthesis steps are complicated, multi-step reactions are required, and the conditions are harsh. The cost of raw materials is also high, resulting in the preparation cost is not low. If the purity requirements are strict, reaching more than 99%, used in high-end pharmaceutical research and development and other fields, the price will rise sharply, or more than 100 yuan per gram.
Furthermore, the following pairs of market supply and demand have a significant impact on the price. If the pharmaceutical industry's new drug research and development has a large increase in demand for compounds containing this structure, but the supply is limited, the price will rise. On the contrary, if the number of production enterprises increases, the supply is sufficient and the demand is stable, the price may be under downward pressure. Coupled with differences in economic levels and logistics costs in different regions, the price will also vary.
To sum up, the market price of 1 - bromo - 3 - chloro - 2,4,5 - trifluorobenzene is difficult to have a fixed value, and it needs to be comprehensively determined according to the actual market conditions.
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