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1-Bromo-3-Chloro-4-Nitrobenzene
Linshang Chemical
|
HS Code |
979132 |
| Chemical Formula | C6H3BrClNO2 |
| Molar Mass | 252.45 g/mol |
| Appearance | Yellow solid |
| Melting Point | 74 - 76 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Purity | Typically available in high purity (e.g., 95%+ in commercial products) |
| Odor | Odorless or faint, characteristic aromatic odor |
| Stability | Stable under normal conditions, but may react with strong oxidizing agents |
As an accredited 1-Bromo-3-Chloro-4-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 1 - bromo - 3 - chloro - 4 - nitrobenzene packaged in a sealed chemical - grade bottle. |
| Storage | 1 - bromo - 3 - chloro - 4 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames as it is potentially flammable. Keep it in a tightly sealed container to prevent vapor release. Store separately from oxidizing agents, reducing agents, and bases to avoid chemical reactions. Label the storage clearly for easy identification and safety. |
| Shipping | 1 - bromo - 3 - chloro - 4 - nitrobenzene is shipped in sealed, corrosion - resistant containers. Adequate cushioning is used to prevent breakage. Shipments follow strict hazardous chemical regulations for safe transportation. |
Competitive 1-Bromo-3-Chloro-4-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 1-Bromo-3-Chloro-4-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the Chinese name for 1 - bromo - 3 - chloro - 4 - nitrobenzene?
The Chinese name of 1-bromo-3-chloro-4-nitrobenzene, according to the ancient classical Chinese style of "Tiangong Kaiwu", should be as follows:
The Chinese title of this compound can be called "bromotrichlorotetranitrobenzene". Those who cover "1-bromo" refer to the benzene ring, which has a bromine atom at the first position; "3-chloro" indicates that there is a chlorine atom at the third position of the benzene ring; "4-nitro" shows that there is a nitro group at the fourth position of the benzene ring. It is called by the name of the place and the linked group. Such a name not only conforms to the general practice of chemical nomenclature, but also follows the concise and comprehensive style of ancient texts. By seeing its name, you can know the approximate structure of its structure. The place is clear, and the groups are ordered. In chemical research and communication, it can accurately convey the structural information of this compound, so as to assist scholars in their exploration and cognition.
The Chinese title of this compound can be called "bromotrichlorotetranitrobenzene". Those who cover "1-bromo" refer to the benzene ring, which has a bromine atom at the first position; "3-chloro" indicates that there is a chlorine atom at the third position of the benzene ring; "4-nitro" shows that there is a nitro group at the fourth position of the benzene ring. It is called by the name of the place and the linked group. Such a name not only conforms to the general practice of chemical nomenclature, but also follows the concise and comprehensive style of ancient texts. By seeing its name, you can know the approximate structure of its structure. The place is clear, and the groups are ordered. In chemical research and communication, it can accurately convey the structural information of this compound, so as to assist scholars in their exploration and cognition.
What are the main uses of 1 - bromo - 3 - chloro - 4 - nitrobenzene?
1 + -Bromo-3 + -chloro-4 + -nitrobenzene, this compound has a wide range of uses in chemical industry.
First, it is often used as a key intermediate in the field of organic synthesis. It can introduce other functional groups through many chemical reactions to build complex organic molecules. For example, through nucleophilic substitution, bromine atoms and chlorine atoms can be replaced by other groups to prepare compounds with special properties, such as fine chemicals such as drugs, pesticides, and dyes.
Second, in the field of materials science, it can participate in the synthesis of high-performance materials. Due to its structure containing halogen atoms and nitro groups, the material is endowed with unique physical and chemical properties, such as enhanced material stability, flame retardancy, etc., so it may have applications in the synthesis of special polymer materials.
Third, in the process of drug development, it may become a lead compound. Its unique molecular structure can interact with specific targets in organisms, providing ideas and bases for the development of new drugs. After structural modification and optimization, drug molecules with good biological activity and pharmacokinetic properties may be obtained.
Fourth, in the field of electronic chemicals, due to its special electronic effects, or potential uses in electronic materials, such as organic semiconductor materials, it affects the electrical properties of materials and meets the specific performance requirements of electronic devices.
In short, 1 + -bromo-3 + -chloro-4 + -nitrobenzene has important uses in many branches of the chemical industry due to its unique molecular structure, which is of great significance for promoting the development of related industries.
First, it is often used as a key intermediate in the field of organic synthesis. It can introduce other functional groups through many chemical reactions to build complex organic molecules. For example, through nucleophilic substitution, bromine atoms and chlorine atoms can be replaced by other groups to prepare compounds with special properties, such as fine chemicals such as drugs, pesticides, and dyes.
Second, in the field of materials science, it can participate in the synthesis of high-performance materials. Due to its structure containing halogen atoms and nitro groups, the material is endowed with unique physical and chemical properties, such as enhanced material stability, flame retardancy, etc., so it may have applications in the synthesis of special polymer materials.
Third, in the process of drug development, it may become a lead compound. Its unique molecular structure can interact with specific targets in organisms, providing ideas and bases for the development of new drugs. After structural modification and optimization, drug molecules with good biological activity and pharmacokinetic properties may be obtained.
Fourth, in the field of electronic chemicals, due to its special electronic effects, or potential uses in electronic materials, such as organic semiconductor materials, it affects the electrical properties of materials and meets the specific performance requirements of electronic devices.
In short, 1 + -bromo-3 + -chloro-4 + -nitrobenzene has important uses in many branches of the chemical industry due to its unique molecular structure, which is of great significance for promoting the development of related industries.
What are the physical properties of 1 - bromo - 3 - chloro - 4 - nitrobenzene?
1 + -Bromo-3 + -chloro-4 + -nitrobenzene is also an organic compound. Its physical properties are quite impressive, and I will describe them in detail today.
Looking at its morphology, at room temperature, 1 + -bromo-3 + -chloro-4 + -nitrobenzene is mostly in the state of a solid state, due to the intermolecular force. The atomic groups such as bromine, chlorine, and nitro in the molecule increase the attractive force between molecules, resulting in a stable solid structure.
As for the color, it often shows a light yellow color, like the first blooming stamen. This color is derived from the absorption and reflection characteristics of each atom in the molecular structure to light. Its molecular structure causes it to absorb light of specific wavelengths, and the rest of the light is reflected into the human eye, giving it a light yellow appearance.
When it comes to odor, 1 + -bromo-3 + -chloro-4 + -nitrobenzene has a special smell. Although it is not a bad smell and pungent, it also has a bright smell. The smell can be known from the smell. The generation of this odor is related to the volatility of the molecule and the interaction of olfactory receptors.
The melting point of 1 + -bromo-3 + -chloro-4 + -nitrobenzene can be known by measurement. The melting point is the temperature limit at which a substance changes from solid to liquid state. Its melting point is affected by intermolecular forces. The presence of bromine, chlorine, and nitro groups strengthens the attractive forces between molecules and causes the melting point to rise.
Furthermore, the boiling point is also an important physical property. The boiling point is the temperature at which a substance changes from liquid to gaseous state. The boiling point of 1 + -bromo-3 + -chloro-4 + -nitrobenzene is higher. Due to the strong intermolecular force, more energy is required to overcome the attractive force between molecules in order to vaporize it.
In terms of solubility, 1 + -bromo-3 + -chloro-4 + -nitrobenzene dissolves very little in water. In water, polar solvents are also used, while 1 + -bromo-3 + -chloro-4 + -nitrobenzene molecules have limited polarity and are "similarly soluble", so it is difficult to dissolve in water. However, in organic solvents such as ethanol and ether, its solubility is better, because organic solvents and 1 + -bromo-3 + -chloro-4 + -nitrobenzene molecules match and can be mixed with each other.
The property of density, 1 + -bromo-3 + -chloro-4 + -nitrobenzene is heavier than water. Placing it in water shows that it sinks to the bottom of the water. Due to the large relative atomic mass of bromine and chlorine in the molecule, the unit volume mass increases, and the density is greater than that of water.
Looking at its morphology, at room temperature, 1 + -bromo-3 + -chloro-4 + -nitrobenzene is mostly in the state of a solid state, due to the intermolecular force. The atomic groups such as bromine, chlorine, and nitro in the molecule increase the attractive force between molecules, resulting in a stable solid structure.
As for the color, it often shows a light yellow color, like the first blooming stamen. This color is derived from the absorption and reflection characteristics of each atom in the molecular structure to light. Its molecular structure causes it to absorb light of specific wavelengths, and the rest of the light is reflected into the human eye, giving it a light yellow appearance.
When it comes to odor, 1 + -bromo-3 + -chloro-4 + -nitrobenzene has a special smell. Although it is not a bad smell and pungent, it also has a bright smell. The smell can be known from the smell. The generation of this odor is related to the volatility of the molecule and the interaction of olfactory receptors.
The melting point of 1 + -bromo-3 + -chloro-4 + -nitrobenzene can be known by measurement. The melting point is the temperature limit at which a substance changes from solid to liquid state. Its melting point is affected by intermolecular forces. The presence of bromine, chlorine, and nitro groups strengthens the attractive forces between molecules and causes the melting point to rise.
Furthermore, the boiling point is also an important physical property. The boiling point is the temperature at which a substance changes from liquid to gaseous state. The boiling point of 1 + -bromo-3 + -chloro-4 + -nitrobenzene is higher. Due to the strong intermolecular force, more energy is required to overcome the attractive force between molecules in order to vaporize it.
In terms of solubility, 1 + -bromo-3 + -chloro-4 + -nitrobenzene dissolves very little in water. In water, polar solvents are also used, while 1 + -bromo-3 + -chloro-4 + -nitrobenzene molecules have limited polarity and are "similarly soluble", so it is difficult to dissolve in water. However, in organic solvents such as ethanol and ether, its solubility is better, because organic solvents and 1 + -bromo-3 + -chloro-4 + -nitrobenzene molecules match and can be mixed with each other.
The property of density, 1 + -bromo-3 + -chloro-4 + -nitrobenzene is heavier than water. Placing it in water shows that it sinks to the bottom of the water. Due to the large relative atomic mass of bromine and chlorine in the molecule, the unit volume mass increases, and the density is greater than that of water.
What are the chemical properties of 1 - bromo - 3 - chloro - 4 - nitrobenzene?
The chemical properties of 1-bromo-3-chloro-4-nitrobenzene are quite complex and valuable to explore. In this compound, bromine, chlorine and nitro groups each show unique properties and interact, resulting in unique chemical characteristics.
Nitro group has strong electron-absorbing properties, which can greatly reduce the electron cloud density of the benzene ring. This property results in a sharp decrease in the activity of the electrophilic substitution reaction of the benzene ring, because the electrophilic reagents are difficult to interact with the benzene ring with the benzene ring with low electron cloud density. However, the presence of nitro groups also makes the electron cloud density of the benzene ring ortho and para-site relatively low, and the meta-position is relatively high. Therefore, during the electrophilic substitution reaction, the new substituent more enters the met
Bromine and chlorine, although they are halogen atoms, have electron-absorbing induction effect, but they also have electron-giving conjugation effect. However, the induction effect is stronger than the conjugation effect, and the overall electron cloud density of the benzene ring is still reduced, but the degree is slightly slower than that of nitro groups. These two affect the reactivity and localization effect of the benzene ring. Due to the high electronegativity of the halogen atom, electrons are attracted, so that the electron cloud density of the benzene ring decreases and the reactivity decreases. However, the electron-giving conjugation effect makes the electron cloud density of the ortho and para-sites relatively higher than that of the meta-site. When electrophilic substitution, new groups tend to enter the ortho and para-sites.
1-bromo-3- In the nucleophilic substitution reaction, the halogen atom can be replaced by the nucleophilic reagent. Due to the electron absorption of the nitro group, the positive electricity of the carbon attached to the halogen atom is enhanced, and it is more vulnerable to the attack of the nucleophilic reagent.
In the reduction reaction, the nitro group can be reduced to different products such as amino groups, depending on the reducing agent used and the reaction conditions. In addition, the compound is widely used in the field of organic synthesis, often used as an intermediate, and complex organic molecular structures can be constructed through various reactions. Due to its unique chemical properties, it can precisely prepare the required organic compounds by different reaction paths, which is of great significance in the fields of drug synthesis and materials science.
Nitro group has strong electron-absorbing properties, which can greatly reduce the electron cloud density of the benzene ring. This property results in a sharp decrease in the activity of the electrophilic substitution reaction of the benzene ring, because the electrophilic reagents are difficult to interact with the benzene ring with the benzene ring with low electron cloud density. However, the presence of nitro groups also makes the electron cloud density of the benzene ring ortho and para-site relatively low, and the meta-position is relatively high. Therefore, during the electrophilic substitution reaction, the new substituent more enters the met
Bromine and chlorine, although they are halogen atoms, have electron-absorbing induction effect, but they also have electron-giving conjugation effect. However, the induction effect is stronger than the conjugation effect, and the overall electron cloud density of the benzene ring is still reduced, but the degree is slightly slower than that of nitro groups. These two affect the reactivity and localization effect of the benzene ring. Due to the high electronegativity of the halogen atom, electrons are attracted, so that the electron cloud density of the benzene ring decreases and the reactivity decreases. However, the electron-giving conjugation effect makes the electron cloud density of the ortho and para-sites relatively higher than that of the meta-site. When electrophilic substitution, new groups tend to enter the ortho and para-sites.
1-bromo-3- In the nucleophilic substitution reaction, the halogen atom can be replaced by the nucleophilic reagent. Due to the electron absorption of the nitro group, the positive electricity of the carbon attached to the halogen atom is enhanced, and it is more vulnerable to the attack of the nucleophilic reagent.
In the reduction reaction, the nitro group can be reduced to different products such as amino groups, depending on the reducing agent used and the reaction conditions. In addition, the compound is widely used in the field of organic synthesis, often used as an intermediate, and complex organic molecular structures can be constructed through various reactions. Due to its unique chemical properties, it can precisely prepare the required organic compounds by different reaction paths, which is of great significance in the fields of drug synthesis and materials science.
What are the preparation methods of 1 - bromo - 3 - chloro - 4 - nitrobenzene?
The method of preparing 1-bromo-3-chloro-4-nitrobenzene can be obtained by starting with benzene and reacting in several steps.
First, nitrate the benzene. Concentrated nitric acid and concentrated sulfuric acid are co-heated as the reaction conditions. After mixing the two, they react with benzene at a suitable temperature. The hydrogen on the benzene ring is replaced by a nitro group to form nitrobenzene. Gein nitro is the meta-site group, and this step is designed to determine the position for the subsequent introduction of other groups.
Second, the halogenation of nitrobenzene is carried out. With chlorine gas as the halogenating agent, under the action of catalysts such as iron trichloride, nitrobenzene reacts with chlorine gas to introduce chlorine atoms into the meta-site of the benz
Third, m-chloronitrobenzene is re-brominated. Liquid bromine is used as raw material, and under the catalysis of iron powder or iron tribromide, m-chloronitrobenzene reacts with bromine to eventually generate 1-bromo-3-chloro-4-nitrobenzene. In this reaction process, the reaction conditions of each step need to be precisely controlled, and factors such as temperature and the proportion of reactants have a significant impact on the purity and yield of the product. And after each reaction step, it is often necessary to go through separation and purification steps, such as distillation, extraction, recrystallization, etc., to obtain pure products to ensure the smooth progress of subsequent reactions. Thus, through this series of reactions, 1-bromo-3-chloro-4-nitrobenzene can be prepared.
First, nitrate the benzene. Concentrated nitric acid and concentrated sulfuric acid are co-heated as the reaction conditions. After mixing the two, they react with benzene at a suitable temperature. The hydrogen on the benzene ring is replaced by a nitro group to form nitrobenzene. Gein nitro is the meta-site group, and this step is designed to determine the position for the subsequent introduction of other groups.
Second, the halogenation of nitrobenzene is carried out. With chlorine gas as the halogenating agent, under the action of catalysts such as iron trichloride, nitrobenzene reacts with chlorine gas to introduce chlorine atoms into the meta-site of the benz
Third, m-chloronitrobenzene is re-brominated. Liquid bromine is used as raw material, and under the catalysis of iron powder or iron tribromide, m-chloronitrobenzene reacts with bromine to eventually generate 1-bromo-3-chloro-4-nitrobenzene. In this reaction process, the reaction conditions of each step need to be precisely controlled, and factors such as temperature and the proportion of reactants have a significant impact on the purity and yield of the product. And after each reaction step, it is often necessary to go through separation and purification steps, such as distillation, extraction, recrystallization, etc., to obtain pure products to ensure the smooth progress of subsequent reactions. Thus, through this series of reactions, 1-bromo-3-chloro-4-nitrobenzene can be prepared.
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