1-Bromo-3-Chloro-5-Fluorobenzene

Linshang Chemical

Specifications

HS Code

724229

Chemical Formula C6H3BrClF
Molecular Weight 211.44
Appearance Liquid (presumably, based on similar haloarenes)
Solubility In Water Insoluble (aromatic halides are generally hydrophobic)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, etc.
Vapor Pressure Low, as with most halogenated aromatic compounds
Stability Stable under normal conditions, but can react with strong bases, nucleophiles, etc.

As an accredited 1-Bromo-3-Chloro-5-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1 - bromo - 3 - chloro - 5 - fluorobenzene in a sealed glass bottle.
Storage 1 - Bromo - 3 - chloro - 5 - fluorobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reactive chemicals, and substances that could initiate chemical reactions to prevent potential hazards.
Shipping 1 - bromo - 3 - chloro - 5 - fluorobenzene is shipped in tightly sealed, corrosion - resistant containers. It's transported under conditions that avoid heat, direct sunlight, and incompatible substances to ensure safe delivery.
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1-Bromo-3-Chloro-5-Fluorobenzene 1-Bromo-3-Chloro-5-Fluorobenzene
General Information
Where to Buy 1-Bromo-3-Chloro-5-Fluorobenzene in China?
As a trusted 1-Bromo-3-Chloro-5-Fluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1-Bromo-3-Chloro-5-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1-bromo-3-chloro-5-fluorobenzene?
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At the same time, in some situations related to traditional Chinese medicine, the juice obtained by boiling specific plants may have certain medicinal effects and can be used to cure diseases and save people.
3,, that is, halogen, has a variety of uses. In cooking, brine, which is often used as braised food, is made by blending spices and salts, etc., which can give meat, eggs and other ingredients a unique and rich flavor, and the braised flavor is deeply loved by the public. In the industrial field, halogen liquid may be used in some metal processing and other processes, such as for specific metal surface treatment processes.
4, Hemp, the main use is to obtain fibers. After hemp plants are treated with hemp, the gums in the hemp skin can be dissolved, making it easier to separate hemp fibers. These hemp fibers can be used in textiles to make various types of hemp fabrics, such as linen, which has good air permeability and is often used in the production of clothing, home textiles, and other supplies. They can also be used to make ropes. Due to the strength and toughness of hemp fibers, the ropes made are durable and suitable for binding, pulling, and other purposes.
What are the physical properties of 1-bromo-3-chloro-5-fluorobenzene
Mercury, bromine, astatine, and thallium are all chemical substances, each with unique physical properties. The following are your points:
Mercury is a liquid at room temperature, with silver flickering, just like flowing silver. Its melting point is extremely low, -38.87 ° C, and its boiling point is not very high, reaching 356.6 ° C. Mercury has a high density of 13.59 g/cm ³, so it is placed on top of other things and can often sink due to its weight. Mercury has excellent fluidity. It can quickly disperse and flow on a flat surface and gather into drops. And mercury has good electrical conductivity and is also used in the field of electricity.
Bromine is the only non-metallic element that is liquid at room temperature and pressure. It is a dark brown-red smoky liquid with a strong pungent odor. Its vapor is toxic and highly corrosive. The melting point of bromine is -7.2 ° C and the boiling point is 58.8 ° C. Bromine is slightly soluble in water, but easily soluble in organic solvents such as carbon tetrachloride.
Astatine is a halogen element and is radioactive. Its half-life is very short, and the content in nature is very small. Astatine has a melting point of 302 ° C and a boiling point of 337 ° C. Due to its active nature, it is easy to combine with other elements and often exists as a compound. It is speculated that astatine may be a dark solid, which is derived from the properties of other halogen elements.
Thallium is a soft heavy metal with a silvery-white sheen on the newly cut surface, which quickly darkens in the air. The melting point of thallium is 303.5 ° C, the boiling point is 1457 ° C, and the density is 11.85 g/cm ³. Thallium has good ductility and can be made into thin sheets or drawn into filaments. Although thallium has conductivity, it is not excellent. And thallium and its compounds are highly toxic, easy to accumulate in the environment and organisms, and are extremely harmful.
What are the synthesis methods of 1-bromo-3-chloro-5-fluorobenzene
To prepare 1-alkyne-3-ene-5-heptyne, the following methods can be used:
First, the reaction of halogenated hydrocarbons and sodium alkyne is used as the basis. First, take a suitable halogenated olefin and make it meet with sodium alkyne. Sodium alkyne is prepared from alkyne and strong bases, such as sodium amide ($NaNH_2 $), in a suitable solvent such as liquid ammonia. Halogenated olefins and sodium alkyne undergo nucleophilic substitution reaction, and the halogen atom is replaced by an alkyne group, and then the carbon frame of the target product is established. In this way, attention should be paid to the selection of halogenated hydrocarbons, and the reactivity and selectivity should be considered. The reaction conditions should also be precisely controlled. Factors such as temperature and solvent
Second, through the coupling reaction of alkynes. Select the appropriate two alkyne substrates and couple them under a suitable catalyst system. Commonly used catalysts such as palladium, copper and other metal complexes. In this process, the metal catalyst activates the triple bonds of alkynes, prompts them to bind to each other, and forms a product containing a polyyne structure. This method requires high activity and selectivity of the catalyst, and the regulation of the reaction conditions is also crucial, such as the selection of ligands, the type and dosage of bases, etc., which will affect the direction and yield of the reaction.
Third, the isomerization reaction of alkynes is taken as the path. The alkyne compound with the appropriate structure is first prepared, and then it is isomerized by suitable catalysts or specific reaction conditions. Transition metal catalysis or external conditions such as heat and light can be used to induce intra-molecular rearrangement, so that the alkyne structure can be transformed to reach the configuration of the target product. This approach requires a deep understanding of the mechanism of isomerization in order to effectively control the reaction process and obtain the required 1-alkyne-3-ene-5-heptyne.
Precautions for storage and transportation of 1-bromo-3-chloro-5-fluorobenzene
When storing and transporting mercury, bromine, and iodine, many things need to be paid attention to.
Mercury is a liquid metal, which is volatile and highly toxic. When storing, use an airtight container to prevent mercury vapor from escaping into the air and causing poisoning. Containers should be sturdy and resistant to mercury corrosion, such as thick-walled glass bottles or metal cans, and must be tightly sealed. When transporting mercury, be sure to ensure that the packaging is firm to prevent damage to the container due to bumps and collisions, and mercury leakage. Protective measures should also be taken during transportation. Transportation personnel should be equipped with professional protective equipment to avoid mercury contact with the skin and respiratory tract.
Bromine is a dark reddish-brown smoky liquid, which is highly corrosive and irritating. Storage of bromine should be placed in a cool and well-ventilated place, away from fire and heat sources, and protected from direct sunlight. Special containers that are resistant to bromine corrosion should be used for storage. For example, glass containers should be equipped with frosted glass stoppers, and protective materials should be wrapped around the bottle to prevent accidental collision and rupture of the container. When transporting bromine, the packaging must be tight and clear labels of corrosive items should be posted. Transportation vehicles should be equipped with corresponding emergency treatment equipment to prevent bromine leakage in a timely manner.
Although iodine is solid, it is easy to sublimate. Storage of iodine should be placed in brown glass bottles, sealed and stored in a cool and dry place to avoid heat and direct sunlight, and slow down the sublimation speed. When transporting iodine, it is also necessary to ensure that the packaging is well sealed to prevent gas leakage after iodine sublimation. At the same time, it is necessary to avoid mixing with other substances that are prone to chemical reactions to prevent danger.
When storing and transporting mercury, bromine, and iodine substances, it is necessary to strictly follow relevant safety regulations and operating procedures, and make protective and emergency preparations to ensure the safety of personnel and the environment from pollution.
What are the effects of 1-bromo-3-chloro-5-fluorobenzene on the environment and human health?
Mercury, arsenic, lead and other substances today pose a serious threat to the environment and human health. Mercury, commonly known as mercury, is a liquid metal. It is highly volatile and can enter the human body through the respiratory tract, digestive tract and skin once it escapes into the environment. In the environment, mercury can persist for a long time and is converted into methylmercury by microbial action, which increases toxicity sharply. Methylmercury is easily enriched in aquatic organisms. If people eat contaminated aquatic products, mercury will accumulate in the body, damage the nervous system, cause cognitive impairment, movement disorders, and children are particularly susceptible, which can cause birth defects.
Arsenic, commonly found in nature, exists in a variety of compounds. Its compounds are toxic, and inorganic arsenic is very toxic. Arsenic pollution in the environment originates from mining, chemical and other activities. Arsenic ingestion by humans through drinking water and food can cause skin lesions and cancer. Long-term exposure can damage liver, kidney and other organs, causing cardiovascular diseases.
Lead is widely used in industry. In the environment, lead can be transmitted through air, water and soil. Children have strong absorption of lead. After lead enters the body, it accumulates in the bones, interfering with hematopoietic, nervous, digestive and other system functions. Lead contamination in children can cause mental retardation and abnormal behavior, while adults have hypertension and kidney damage.
Mercury, arsenic and lead are all highly toxic substances. They are persistent and difficult to eliminate in the environment. They accumulate through the food chain and eventually endanger human health. Therefore, it is important to strictly control their discharge and protect the well-being of the environment and people.