1-Bromo-3-Chloro-5-Methoxybenzene
Linshang Chemical
HS Code |
741267 |
Chemical Formula | C7H6BrClO |
Molar Mass | 221.48 g/mol |
Appearance | Solid (presumably, based on similar aromatic halides) |
Solubility In Water | Low solubility in water, as it is an aromatic non - polar compound |
Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform, etc. |
As an accredited 1-Bromo-3-Chloro-5-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 100g of 1 - bromo - 3 - chloro - 5 - methoxybenzene in a sealed glass bottle. |
Storage | 1 - Bromo - 3 - chloro - 5 - methoxybenzene should be stored in a cool, dry, well - ventilated area away from sources of heat, ignition, and incompatible substances. Keep it in a tightly sealed container made of materials resistant to chemical corrosion, such as glass or certain plastics. Avoid exposure to moisture and strong oxidizing agents to prevent degradation and potential safety hazards. |
Shipping | 1 - bromo - 3 - chloro - 5 - methoxybenzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict chemical transportation regulations, ensuring proper handling to prevent leakage and maintain safety during transit. |
Competitive 1-Bromo-3-Chloro-5-Methoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 1-Bromo-3-Chloro-5-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In terms of its solubility, it has limited solubility in water, but it has good solubility in organic solvents, such as alcohols and ethers. This property is derived from the proportion and distribution of its molecular affinity and hydrophobic groups, and the hydrophilic methyl groups, which make it compatible with organic solvents.
Thermal stability is also important. When heated moderately, its structure can be stabilized, but beyond a certain temperature, the bonds in the molecule may be broken or rearranged. This change comes from the consumption of bond energy, and changes occur when the energy provided by heat is the binding energy of the super bond.
Its chemical reactivity also has considerable advantages. Because oxygen, chlorine and other atoms exist in the molecule, under specific conditions, they can lead to nucleophilic substitution, oxidation and other reactions. For example, chlorine atoms can become the target of nucleophilic reagents and are replaced by nucleophilic groups; hydroxyl or methoxy groups can be oxidized in an oxidizing environment.
Spectral characteristics, in the infrared spectrum, hydroxyl groups, chlorine atoms, carbon-oxygen bonds, etc. have unique absorption peaks, which can be based on their structures. In the NMR spectrum, hydrogen and carbon atoms at different positions show specific displacement signals according to their chemical environments, which is a powerful tool for analyzing their molecular structures.
In summary, 1 + -hydroxyl-3-chloro-5-methoxyphenyl, with its diverse chemical properties, has potential applications and research value in chemical, pharmaceutical and other fields.
First, it can be prepared by the reaction of phenolic compounds with halogenated hydrocarbons under basic conditions. Using phenol as the starting material, the hydroxyl group of phenol has a certain nucleophilicity. When encountering halogenated hydrocarbons, under the action of bases, the phenolic hydroxyl oxygen atoms attack the carbon atoms of halogenated hydrocarbons, and the halogen atoms leave to form ether bonds. For example, if you want to synthesize 1-ether-3-alkane-5-methoxybenzene, you can choose a suitable phenol, which has a corresponding methoxy group on the phenyl ring, and react with halogenated hydrocarbons containing a specific alkane structure. In this process, the base can be selected from potassium carbonate, etc., and the reaction can be carried out in a suitable organic solvent such as N, N-dimethylformamide (DMF), which can promote the smooth occurrence of the reaction.
Second, the Williamson synthesis method is also a common method. This method uses sodium alcohol or sodium phenol to react with halogenated hydrocarbons. First, the alcohol or phenol is converted into the corresponding sodium alcohol or sodium phenol to enhance its nucleophilicity, and then it encounters the halogenated hydrocarbon. The halogen atom of the halogenated hydrocarbon is replaced by a nucleophilic reagent to form an ether bond. For example, when preparing this target compound, the phenol containing methoxy group can be made into sodium phenol, and the halogenated hydrocarbon with a specific alkane structure and halogenated atom can be reacted in a suitable solvent, such as in a solvent such as anhydrous ethanol. The reaction conditions need to be properly controlled for temperature and reaction time to improve the yield.
Third, the reaction of aryl borate with halogenated hydrocarbons or halogenated hydrocarbons under transition metal catalysis can also be achieved. Aryl borates have good stability and reactivity. Under the catalysis of transition metals such as palladium, they can be coupled with halogenated hydrocarbons or halogenated hydrocarbons to form carbon-oxygen bonds, and then the target ether compounds can be synthesized. For example, when synthesizing 1-ether-3-alkyl-5-methoxybenzene, suitable methoxy-containing aryl borates can be selected, and the corresponding halogenated hydrocarbons can be reacted in a suitable reaction system in the presence of palladium catalysts and ligands. Such reactions usually require harsh reaction conditions, and factors such as catalyst dosage, reaction temperature and reaction time need to be precisely controlled to achieve efficient synthesis.
Mercury, in the medical field, was used in the past to make thermometers to measure body temperature by its thermal expansion and contraction properties. However, due to its toxicity, it has been gradually replaced by electronic thermometers. In the chemical industry, mercury can be used as a catalyst to assist in the progress of specific chemical reactions. For example, in the production of vinyl chloride, mercury chloride was once an important catalyst, but due to its toxicity to the environment and human body, it is also seeking alternatives. In the field of metallurgy, amalgamation has been used to extract precious metals such as gold and silver, using the characteristics of mercury and metal to form amalgam, and then distilling to separate the metal.
Arsenic has been used as an insecticide and herbicide in agriculture to remove pests and weeds to protect crops. However, due to its strong toxicity and great harm to the environment and humans and animals, its use has been strictly restricted today. In the semiconductor industry, gallium arsenide is an important compound semiconductor material with high electron mobility and moderate bandgap width. It is used to make high-speed, high-frequency and optoelectronic devices, such as Light Emitting Diode, laser diode, etc.
Methoxybenzene is based on the field of medicine. Many drug molecules contain this structure, which can adjust drug activity, solubility and bioavailability by virtue of its unique chemical properties. For example, in some cardiovascular drugs and antibacterial drugs, the presence of methoxyphenyl is crucial to the efficacy of drugs. In the fragrance industry, compounds containing methoxyphenyl groups can be used as fragrance ingredients to give products a unique aroma. For example, in some floral fragrances, this structure can enhance the richness and layering of the fragrance. In the field of materials science, polymer materials containing methoxyphenyl groups can improve the physical and chemical properties of materials, such as solubility and thermal stability, and are used in coatings, adhesives and other products.
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As for arsenic, it is also a highly toxic element. Its storage also needs to be properly sealed to prevent dust from flying and causing human inhalation. It should be stored in a specific chemical storage cabinet, which should have good anti-leakage and ventilation functions. The storage environment needs to be kept dry. Due to humid environment or changes in arsenic compounds, its stability will be affected and the risk of leakage will increase.
And 5 + -methoxyphenyl, when storing, its chemical properties need to be considered. This substance may be sensitive to light and heat, so it should be stored in a dark place, and the temperature should not be too high. Brown glass bottles can be used to block chemical reactions caused by light exposure. It also needs to be sealed to prevent interaction with oxygen and moisture in the air. Storage should also be kept away from fire sources and strong oxidants, as they may be flammable or prone to violent reactions with oxidants. In short, the storage of these three should be to ensure safety and stability, and follow strict storage specifications to avoid hazards.

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