Linshang Chemical
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1-Bromo-4-Chloro-2,5-Difluorobenzene
|
HS Code |
356441 |
| Chemical Formula | C6H2BrClF2 |
| Molar Mass | 227.43 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | Around 190 - 195 °C |
| Density | Approx. 1.8 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane |
| Vapor Pressure | Low |
As an accredited 1-Bromo-4-Chloro-2,5-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - bromo - 4 - chloro - 2,5 - difluorobenzene: Packed in 500 - gram bottles. |
| Storage | 1 - Bromo - 4 - chloro - 2,5 - difluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials like glass or certain plastics, to prevent leakage and exposure to air and moisture, which could potentially lead to decomposition or reaction. |
| Shipping | 1 - Bromo - 4 - chloro - 2,5 - difluorobenzene is shipped in sealed, corrosion - resistant containers. Shipment follows strict hazardous chemical regulations, ensuring proper handling, labeling, and transport to prevent any risks during transit. |
Competitive 1-Bromo-4-Chloro-2,5-Difluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Bromo-4-Chloro-2,5-Difluorobenzene in China?
As a trusted 1-Bromo-4-Chloro-2,5-Difluorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Bromo-4-Chloro-2,5-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 1-bromo-4-chloro-2,5-difluorobenzene?
Mercury is also known as mercury. Its essence is agile, and at room temperature, it is in a liquid state, white in color and metallic in light. It is good in nature and flows away, and it is elusive when touched.
Mercury is toxic. If people accidentally touch it, smell it, or eat it, it can cause disease, and even endanger life. And mercury can form alloys with many metals, called amalgams.
Carbon tetrachloride, a colorless liquid, has a special smell. Its density is greater than that of water, and it is insoluble in water. It is a good organic solvent. It is relatively stable in nature and non-flammable. It is often used as an extractant.
Diethyl ether, a colorless and transparent liquid, has a special fragrance, is highly volatile, and its vapor is heavier than air. Diethyl ether has the effect of anesthesia and has been used in the field of medical anesthesia in the past. However, it is also flammable and explosive, and it is easy to cause combustion and explosion in case of open flames and hot topics. And diethyl ether is placed in the air for a long time, and it is easy to generate explosive peroxides. Special caution is required when using it.
Mercury is toxic. If people accidentally touch it, smell it, or eat it, it can cause disease, and even endanger life. And mercury can form alloys with many metals, called amalgams.
Carbon tetrachloride, a colorless liquid, has a special smell. Its density is greater than that of water, and it is insoluble in water. It is a good organic solvent. It is relatively stable in nature and non-flammable. It is often used as an extractant.
Diethyl ether, a colorless and transparent liquid, has a special fragrance, is highly volatile, and its vapor is heavier than air. Diethyl ether has the effect of anesthesia and has been used in the field of medical anesthesia in the past. However, it is also flammable and explosive, and it is easy to cause combustion and explosion in case of open flames and hot topics. And diethyl ether is placed in the air for a long time, and it is easy to generate explosive peroxides. Special caution is required when using it.
What are the common uses of 1-bromo-4-chloro-2,5-difluorobenzene?
"Tiangong Kaiwu" is a scientific and technological masterpiece written by Song Yingxing in the Ming Dynasty, which describes in detail the preparation and application of many substances. The common uses of mercury, tin, and divinylbenzene are as follows according to the ancient saying:
Mercury, also known as mercury, is liquid at room temperature, silver-white and metallic luster. Its unique nature is quite important in the art of alchemy. The ancients believed that alchemy can cause longevity, and mercury was often the main material for alchemy. Such as Ge Hong and other alchemists, who used mercury to refine with other things to seek elixir. In the field of metallurgy, mercury is also very useful. Gold is often extracted by mixing mercury, and mercury and gold are used to form amalgam, so that gold can be separated from ore. This technique was commonly used in ancient mining. In addition, mercury is also used in medicine. According to ancient medical records, mercury can be used as medicine to treat scabies, acne and other diseases. However, mercury is toxic, so the dosage and usage should be cautious.
Tin is soft and malleable, and its color is silvery white and slightly blue. Its common uses are the first to be used in castings. The ancients used tin to cast tripods, pots, candlesticks and other things. Tin is light and corrosion-resistant, with practical and ornamental effects. Since the Shang and Zhou Dynasties, bronze casting has often been added with tin. Bronze is a copper-tin alloy. Adding tin can increase the hardness and toughness of bronze, making the casting more exquisite and durable. Many bronze heavy weapons contain tin. In terms of solder, tin is also indispensable. Due to its low melting point, tin can be well connected to metal parts. In ancient times, metal utensils were repaired and manufactured, and tin was often relied on as solder.
Divinylbenzene, although there was no such chemical name when "Tiangong Kaiwu" was written, it is extrapolated from today's chemical knowledge. If you compare it to something with similar functions at that time, or it is related to resin materials. In today's chemical industry, divinylbenzene is an important cross-linking agent, used in the manufacture of ion exchange resins, synthetic rubber, etc. Although there were no such fine chemical products in ancient times, there were similar ideas in the process of making paints and bonding materials. For example, in ancient times, lacquers were made, or similar substances that could be crosslinked and cured were used to enhance the performance of the paint. In the production of adhesive materials, it was also necessary to crosslink the ingredients to increase the adhesion, or it was similar to the crosslinking effect of divinylbenzene.
Mercury, also known as mercury, is liquid at room temperature, silver-white and metallic luster. Its unique nature is quite important in the art of alchemy. The ancients believed that alchemy can cause longevity, and mercury was often the main material for alchemy. Such as Ge Hong and other alchemists, who used mercury to refine with other things to seek elixir. In the field of metallurgy, mercury is also very useful. Gold is often extracted by mixing mercury, and mercury and gold are used to form amalgam, so that gold can be separated from ore. This technique was commonly used in ancient mining. In addition, mercury is also used in medicine. According to ancient medical records, mercury can be used as medicine to treat scabies, acne and other diseases. However, mercury is toxic, so the dosage and usage should be cautious.
Tin is soft and malleable, and its color is silvery white and slightly blue. Its common uses are the first to be used in castings. The ancients used tin to cast tripods, pots, candlesticks and other things. Tin is light and corrosion-resistant, with practical and ornamental effects. Since the Shang and Zhou Dynasties, bronze casting has often been added with tin. Bronze is a copper-tin alloy. Adding tin can increase the hardness and toughness of bronze, making the casting more exquisite and durable. Many bronze heavy weapons contain tin. In terms of solder, tin is also indispensable. Due to its low melting point, tin can be well connected to metal parts. In ancient times, metal utensils were repaired and manufactured, and tin was often relied on as solder.
Divinylbenzene, although there was no such chemical name when "Tiangong Kaiwu" was written, it is extrapolated from today's chemical knowledge. If you compare it to something with similar functions at that time, or it is related to resin materials. In today's chemical industry, divinylbenzene is an important cross-linking agent, used in the manufacture of ion exchange resins, synthetic rubber, etc. Although there were no such fine chemical products in ancient times, there were similar ideas in the process of making paints and bonding materials. For example, in ancient times, lacquers were made, or similar substances that could be crosslinked and cured were used to enhance the performance of the paint. In the production of adhesive materials, it was also necessary to crosslink the ingredients to increase the adhesion, or it was similar to the crosslinking effect of divinylbenzene.
What are the synthesis methods of 1-bromo-4-chloro-2,5-difluorobenzene?
The synthesis methods of 1 + -alkenyl-4-alkynyl-2,5-divinylbenzene include the following:
First, through the catalytic coupling reaction of transition metals. This is a commonly used method. Compounds containing alkenyl groups, alkynyl groups, and halobenzene can be coupled by transition metal catalysts such as palladium and nickel. If a suitable halogenated benzene derivative is selected, in the presence of palladium catalyst and ligand, with alkenyl borate, alkynyl halide, etc., in a suitable solvent and base environment, after coupling reaction, the carbon-carbon bond of the target molecule is gradually constructed, and the purpose of synthesizing 1 + -ene-4-alkynyl-2,5-divinylbenzene is achieved. The advantages of this method are that the reaction selectivity is high, the conditions are relatively mild, and the structure and purity of the product can be effectively controlled.
Second, the cyclic trimerization of alkynes is used. Under the action of a suitable catalyst, a specific alkyne monomer is subjected to a cyclic trimerization reaction to form a product with a benzene ring structure. If the structure of the alkyne monomer is carefully designed to contain the required functional groups such as alkenyl and alkynyl groups, after the cyclic trimerization reaction, 1 + -alkenyl-4-alkynyl-2,5-divinylbenzene can be directly generated. The key to this approach lies in the selection of catalysts and the precise regulation of reaction conditions to ensure that the reaction proceeds in the expected direction and avoid unnecessary side reactions.
Third, through the multi-step reaction strategy in organic synthesis. First, a simple organic compound is used as the starting material, and through multi-step reaction, the functional groups such as alkenyl and alkynyl are gradually introduced, and the phenyl ring structure is constructed. For example, suitable functional groups can be introduced from aromatic derivatives through substitution reactions, and then gradually modified by alkylation reactions, alkenylation reactions, etc., and finally the target product can be synthesized through cyclization and other reactions. Although this method has complicated steps, the reaction route can be flexibly adjusted according to needs, and the selection range of raw materials is also wide.
First, through the catalytic coupling reaction of transition metals. This is a commonly used method. Compounds containing alkenyl groups, alkynyl groups, and halobenzene can be coupled by transition metal catalysts such as palladium and nickel. If a suitable halogenated benzene derivative is selected, in the presence of palladium catalyst and ligand, with alkenyl borate, alkynyl halide, etc., in a suitable solvent and base environment, after coupling reaction, the carbon-carbon bond of the target molecule is gradually constructed, and the purpose of synthesizing 1 + -ene-4-alkynyl-2,5-divinylbenzene is achieved. The advantages of this method are that the reaction selectivity is high, the conditions are relatively mild, and the structure and purity of the product can be effectively controlled.
Second, the cyclic trimerization of alkynes is used. Under the action of a suitable catalyst, a specific alkyne monomer is subjected to a cyclic trimerization reaction to form a product with a benzene ring structure. If the structure of the alkyne monomer is carefully designed to contain the required functional groups such as alkenyl and alkynyl groups, after the cyclic trimerization reaction, 1 + -alkenyl-4-alkynyl-2,5-divinylbenzene can be directly generated. The key to this approach lies in the selection of catalysts and the precise regulation of reaction conditions to ensure that the reaction proceeds in the expected direction and avoid unnecessary side reactions.
Third, through the multi-step reaction strategy in organic synthesis. First, a simple organic compound is used as the starting material, and through multi-step reaction, the functional groups such as alkenyl and alkynyl are gradually introduced, and the phenyl ring structure is constructed. For example, suitable functional groups can be introduced from aromatic derivatives through substitution reactions, and then gradually modified by alkylation reactions, alkenylation reactions, etc., and finally the target product can be synthesized through cyclization and other reactions. Although this method has complicated steps, the reaction route can be flexibly adjusted according to needs, and the selection range of raw materials is also wide.
What are the precautions for storing and transporting 1-bromo-4-chloro-2,5-difluorobenzene?
When storing mercury, arsenic, and dioxin, there are many things to pay attention to.
Mercury is extremely toxic and volatile at room temperature. When storing, use a sealed container to prevent the escape of mercury vapor. Because of its high density, the container should be solid and leak-proof, and placed in a cool, well-ventilated place, away from heat and fire sources. During handling, be careful to prevent mercury from being spilled due to damage to the container. If it is unfortunate to spill, cover it with sulfur powder immediately, so that the mercury reacts with it to form mercury sulfide, and then clean it up. Do not touch it with your hands.
Arsenic is also highly toxic. Store in a dry environment, and it is easy to generate toxic gases due to contact with water. The package should be tightly closed and clearly marked "toxic". During transportation, avoid mixing with acids and alkalis to prevent reactions, and transportation vehicles should be equipped with corresponding emergency treatment equipment.
DiBritish persistent organic pollutants, chemically stable. Storage should be protected from light, low temperature, dry place to prevent its decomposition and transformation. Packaging materials must have good barrier properties to prevent dioxin from seeping out. During transportation, follow strict regulations and standards, and take protective measures to prevent leakage. Once leaked, it is extremely difficult to deal with, because it is difficult to degrade and bioaccumulative, it will cause serious environmental pollution and health hazards.
Mercury, arsenic, and dioxin are all dangerous substances. During the storage and transportation process, they must be operated in strict accordance with regulations, and protection and emergency preparations must be made to ensure the safety of personnel and the environment from pollution.
Mercury is extremely toxic and volatile at room temperature. When storing, use a sealed container to prevent the escape of mercury vapor. Because of its high density, the container should be solid and leak-proof, and placed in a cool, well-ventilated place, away from heat and fire sources. During handling, be careful to prevent mercury from being spilled due to damage to the container. If it is unfortunate to spill, cover it with sulfur powder immediately, so that the mercury reacts with it to form mercury sulfide, and then clean it up. Do not touch it with your hands.
Arsenic is also highly toxic. Store in a dry environment, and it is easy to generate toxic gases due to contact with water. The package should be tightly closed and clearly marked "toxic". During transportation, avoid mixing with acids and alkalis to prevent reactions, and transportation vehicles should be equipped with corresponding emergency treatment equipment.
DiBritish persistent organic pollutants, chemically stable. Storage should be protected from light, low temperature, dry place to prevent its decomposition and transformation. Packaging materials must have good barrier properties to prevent dioxin from seeping out. During transportation, follow strict regulations and standards, and take protective measures to prevent leakage. Once leaked, it is extremely difficult to deal with, because it is difficult to degrade and bioaccumulative, it will cause serious environmental pollution and health hazards.
Mercury, arsenic, and dioxin are all dangerous substances. During the storage and transportation process, they must be operated in strict accordance with regulations, and protection and emergency preparations must be made to ensure the safety of personnel and the environment from pollution.
What are the effects of 1-bromo-4-chloro-2,5-difluorobenzene on the environment and human health?
Today there are cyanide, mercury, and vinyl chloride, which have a great impact on the environment and human health.
Cyanide is highly toxic. In the environment, if cyanide leaks, it can cause water and soil pollution. When it enters rivers, lakes and seas, aquatic organisms bear the brunt, or cause a large number of deaths such as fish and shrimp, which disrupts the balance of the surrounding water ecology. In the soil, it affects the activities of soil microorganisms and hinders plant growth. And if people accidentally contact or ingest cyanide-containing substances, it can cause dizziness, headache, fatigue, breathing difficulties, coma, convulsions, and even death. Its poison can hinder cell respiration, starve the body of oxygen, and endanger life.
Mercury is also a very harmful pollutant. In the environment, mercury can circulate between water, soil, and atmosphere. Mercury emitted by industry is deposited into soil and water through the atmosphere. In water, mercury can be converted into methylmercury by microorganisms, which is more toxic. Methylmercury is easily enriched in aquatic organisms and transmitted through the food chain. If people eat contaminated fish and shellfish, methylmercury will accumulate in the human body. It damages the nervous system, especially in fetuses and children, and can cause mental retardation and neurological dysfunction.
Dichloroethylene has certain toxicity. In the environment, it can volatilize into the atmosphere, participate in photochemical reactions, affect air quality, and cause photochemical smog and other hazards. If dichloroethylene contaminates soil and water, plant roots will absorb it, affecting growth and development, and causing crop production to decrease. Long-term exposure to dichloroethylene-containing environments can irritate the eyes and respiratory tract, cause skin allergies, and have potential carcinogenic risks, damaging human liver, kidneys and other organs.
Therefore, cyanide, mercury, and dichloroethylene are all serious hazards to the environment and human health. We should take care to prevent them, and strictly control their discharge and use to protect the environment and human well-being.
Cyanide is highly toxic. In the environment, if cyanide leaks, it can cause water and soil pollution. When it enters rivers, lakes and seas, aquatic organisms bear the brunt, or cause a large number of deaths such as fish and shrimp, which disrupts the balance of the surrounding water ecology. In the soil, it affects the activities of soil microorganisms and hinders plant growth. And if people accidentally contact or ingest cyanide-containing substances, it can cause dizziness, headache, fatigue, breathing difficulties, coma, convulsions, and even death. Its poison can hinder cell respiration, starve the body of oxygen, and endanger life.
Mercury is also a very harmful pollutant. In the environment, mercury can circulate between water, soil, and atmosphere. Mercury emitted by industry is deposited into soil and water through the atmosphere. In water, mercury can be converted into methylmercury by microorganisms, which is more toxic. Methylmercury is easily enriched in aquatic organisms and transmitted through the food chain. If people eat contaminated fish and shellfish, methylmercury will accumulate in the human body. It damages the nervous system, especially in fetuses and children, and can cause mental retardation and neurological dysfunction.
Dichloroethylene has certain toxicity. In the environment, it can volatilize into the atmosphere, participate in photochemical reactions, affect air quality, and cause photochemical smog and other hazards. If dichloroethylene contaminates soil and water, plant roots will absorb it, affecting growth and development, and causing crop production to decrease. Long-term exposure to dichloroethylene-containing environments can irritate the eyes and respiratory tract, cause skin allergies, and have potential carcinogenic risks, damaging human liver, kidneys and other organs.
Therefore, cyanide, mercury, and dichloroethylene are all serious hazards to the environment and human health. We should take care to prevent them, and strictly control their discharge and use to protect the environment and human well-being.
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