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1-Bromo-4-Chloro-2,6-Difluorobenzene
|
HS Code |
291137 |
| Chemical Formula | C6H2BrClF2 |
| Molar Mass | 227.43 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | Approximately 170 - 175 °C |
| Density | Data may vary, around 1.8 - 2.0 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Purity | Typically sold in high purity, e.g., 95%+ in commercial products |
As an accredited 1-Bromo-4-Chloro-2,6-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 1 - bromo - 4 - chloro - 2,6 - difluorobenzene packaged in a sealed glass bottle. |
| Storage | 1 - Bromo - 4 - chloro - 2,6 - difluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials like glass or certain plastics. Store it separately from oxidizing agents and reactive chemicals to prevent potential chemical reactions. |
| Shipping | 1 - bromo - 4 - chloro - 2,6 - difluorobenzene is shipped in well - sealed, corrosion - resistant containers. Shipment adheres to strict chemical transportation regulations, ensuring safe transit to prevent any leakage or hazard during the journey. |
Competitive 1-Bromo-4-Chloro-2,6-Difluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Bromo-4-Chloro-2,6-Difluorobenzene in China?
As a trusted 1-Bromo-4-Chloro-2,6-Difluorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Bromo-4-Chloro-2,6-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1-bromo-4-chloro-2,6-difluorobenzene?
The main uses of 1 + - + mercury + - + 4 + - + bromine + - + 2,6 + - + diethyl ether are as follows:
Mercury is unique and has a wide range of uses. In ancient times, it was often used in alchemy techniques. The alchemists believed that it had magical effects and could refine the so-called life-prolonging elixir. Although it was absurd, it reflected the understanding and utilization of mercury at that time. In the medical field, mercury also played an important role. For example, mercury agents were used to treat syphilis and other diseases, but due to the toxicity of mercury, it is now used with extreme caution. In addition, mercury is indispensable in the chemical industry, and many mercury compounds are used in the preparation of catalysts and electrode materials. In terms of measuring instruments, mercury is used in the manufacture of thermometers, barometers, etc. due to its special physical properties, and its thermal expansion and contraction characteristics are used to accurately measure temperature and air pressure.
Bromine is also used in a variety of applications. In the pharmaceutical industry, bromide is often used as a sedative, which can soothe nerves and relieve anxiety. In the chemical industry, bromine is a key raw material for the synthesis of many important organic compounds, such as bromine-containing flame retardants. It is widely used in electronic equipment, building materials, etc., which can effectively improve the flame retardancy of materials and reduce the risk of fire. In the petroleum industry, bromine is involved in the oil extraction and refining process, and brominants can be used to improve the quality and performance of oil products.
2,6-diethyl ether, which has a significant position in the field of organic It is often used as an excellent solvent because of its good solubility to many organic compounds, which can provide a suitable reaction environment for organic reactions and promote the smooth progress of the reaction. At the same time, it acts as an important intermediate in the synthesis of some fine chemical products, and can be converted into complex organic compounds with unique functions through a series of chemical reactions. It is widely used in the pharmaceutical, fragrance, pesticide and other industries to help these industries develop new products and meet the needs of different fields.
Mercury is unique and has a wide range of uses. In ancient times, it was often used in alchemy techniques. The alchemists believed that it had magical effects and could refine the so-called life-prolonging elixir. Although it was absurd, it reflected the understanding and utilization of mercury at that time. In the medical field, mercury also played an important role. For example, mercury agents were used to treat syphilis and other diseases, but due to the toxicity of mercury, it is now used with extreme caution. In addition, mercury is indispensable in the chemical industry, and many mercury compounds are used in the preparation of catalysts and electrode materials. In terms of measuring instruments, mercury is used in the manufacture of thermometers, barometers, etc. due to its special physical properties, and its thermal expansion and contraction characteristics are used to accurately measure temperature and air pressure.
Bromine is also used in a variety of applications. In the pharmaceutical industry, bromide is often used as a sedative, which can soothe nerves and relieve anxiety. In the chemical industry, bromine is a key raw material for the synthesis of many important organic compounds, such as bromine-containing flame retardants. It is widely used in electronic equipment, building materials, etc., which can effectively improve the flame retardancy of materials and reduce the risk of fire. In the petroleum industry, bromine is involved in the oil extraction and refining process, and brominants can be used to improve the quality and performance of oil products.
2,6-diethyl ether, which has a significant position in the field of organic It is often used as an excellent solvent because of its good solubility to many organic compounds, which can provide a suitable reaction environment for organic reactions and promote the smooth progress of the reaction. At the same time, it acts as an important intermediate in the synthesis of some fine chemical products, and can be converted into complex organic compounds with unique functions through a series of chemical reactions. It is widely used in the pharmaceutical, fragrance, pesticide and other industries to help these industries develop new products and meet the needs of different fields.
What are the physical properties of 1-bromo-4-chloro-2,6-difluorobenzene?
1 + - ++ - + 4 + - + arsenic + - + 2,6 + - + divinylbenzene, its physical properties are as follows:
, which is white, bright, hard and brittle gold. With crystalline film, it loses light in the tide and air, and then ignites to form white oxidation. Its melting height is 630.74 ° C, boiling temperature is 1587 ° C. Density is 6.697g/cm ³. Its Mohs hardness is 3, it has a certain brittleness, and it is good and has good corrosion resistance.
Arsenic has gray, black and brown isotopes. Among them, gray arsenic is the most fixed, and gray has gold light and brittle solid. Melting temperature is 817 ° C (28 ° C), and it can be added to 613 ° C. Density is 5.727g/cm ³, poor stability, low chemical activity, and easy to be oxidized in tidal air.
2,6-divinylbenzene, often in low color to light color liquid. It has a special taste, is soluble in water, and can be soluble in multi-soluble liquid. Its boiling temperature is 207-208 ° C, melting temperature is -72 ° C, density is 0.913g/cm ³, and refractive index is 1.566-1.568. Because its molecules contain hydrogen, it has certain chemical activity, can be multi-added into anti-oxidation, etc., and is flammable, flammable liquid.
, which is white, bright, hard and brittle gold. With crystalline film, it loses light in the tide and air, and then ignites to form white oxidation. Its melting height is 630.74 ° C, boiling temperature is 1587 ° C. Density is 6.697g/cm ³. Its Mohs hardness is 3, it has a certain brittleness, and it is good and has good corrosion resistance.
Arsenic has gray, black and brown isotopes. Among them, gray arsenic is the most fixed, and gray has gold light and brittle solid. Melting temperature is 817 ° C (28 ° C), and it can be added to 613 ° C. Density is 5.727g/cm ³, poor stability, low chemical activity, and easy to be oxidized in tidal air.
2,6-divinylbenzene, often in low color to light color liquid. It has a special taste, is soluble in water, and can be soluble in multi-soluble liquid. Its boiling temperature is 207-208 ° C, melting temperature is -72 ° C, density is 0.913g/cm ³, and refractive index is 1.566-1.568. Because its molecules contain hydrogen, it has certain chemical activity, can be multi-added into anti-oxidation, etc., and is flammable, flammable liquid.
What are the synthesis methods of 1-bromo-4-chloro-2,6-difluorobenzene?
To prepare 1-bromo-4-iodine-2,6-divinylbenzene, the following ancient methods can be used.
First, benzene is used as the starting material. First, benzene and bromine are catalyzed by iron bromide to undergo an electrophilic substitution reaction to obtain bromobenzene. In this reaction, iron bromide promotes the polarization of bromine molecules to generate bromine positive ions, which attack the benzene ring and replace hydrogen atoms to obtain bromobenzene.
Next, bromobenzene is reacted with iodine under specific catalysts and conditions. 1-Bromo-4-iodobenzene can be obtained by substituting an iodine atom for the hydrogen in the p-position of bromobenzene at an appropriate temperature and solvent. This step requires careful control of the reaction conditions to maintain the selectivity of the p-position substitution.
Then, 1-Bromo-4-iodobenzene reacts with vinyl Grignard reagent. Vinyl Grignard reagent is prepared from ethylene halide and magnesium. In anhydrous ether and other solvents, nucleophilic substitution occurs with 1-bromo-4-iodobenzene, and vinyl substitutes bromine atoms to obtain 1-bromo-4-iodine-2,6-divinylbenzene. This process requires strict reaction environment and needs to be anhydrous and oxygen-free to prevent Grignard reagent from failing.
Second, aromatics containing corresponding substituents can also be used as starting materials. If there are suitable 2,6-disubstituted aromatics, and the substituents can be appropriately converted into vinyl, and iodine can be introduced into the para-position and bromine can be introduced into the ortho-position, the target product can be prepared through a series of reactions. First, according to the principle of electrophilic substitution, bromine and iodine atoms are introduced, and then the existing substituents are converted into vinyl groups through functional group conversion. For example, if the starting material is 2,6-bis (a readily convertible group) aromatic hydrocarbon, iodine can be introduced into the para-position first, bromine can be introduced into the ortho-position, and then the 2,6-position group can be converted into vinyl through elimination, addition and other reactions, and 1-bromo-4-iodine-2,6-divinylbenzene can be obtained. However, this approach requires precise design of the structure of the starting material, and fine regulation of the reaction conditions at each step to achieve the ideal yield and purity.
First, benzene is used as the starting material. First, benzene and bromine are catalyzed by iron bromide to undergo an electrophilic substitution reaction to obtain bromobenzene. In this reaction, iron bromide promotes the polarization of bromine molecules to generate bromine positive ions, which attack the benzene ring and replace hydrogen atoms to obtain bromobenzene.
Next, bromobenzene is reacted with iodine under specific catalysts and conditions. 1-Bromo-4-iodobenzene can be obtained by substituting an iodine atom for the hydrogen in the p-position of bromobenzene at an appropriate temperature and solvent. This step requires careful control of the reaction conditions to maintain the selectivity of the p-position substitution.
Then, 1-Bromo-4-iodobenzene reacts with vinyl Grignard reagent. Vinyl Grignard reagent is prepared from ethylene halide and magnesium. In anhydrous ether and other solvents, nucleophilic substitution occurs with 1-bromo-4-iodobenzene, and vinyl substitutes bromine atoms to obtain 1-bromo-4-iodine-2,6-divinylbenzene. This process requires strict reaction environment and needs to be anhydrous and oxygen-free to prevent Grignard reagent from failing.
Second, aromatics containing corresponding substituents can also be used as starting materials. If there are suitable 2,6-disubstituted aromatics, and the substituents can be appropriately converted into vinyl, and iodine can be introduced into the para-position and bromine can be introduced into the ortho-position, the target product can be prepared through a series of reactions. First, according to the principle of electrophilic substitution, bromine and iodine atoms are introduced, and then the existing substituents are converted into vinyl groups through functional group conversion. For example, if the starting material is 2,6-bis (a readily convertible group) aromatic hydrocarbon, iodine can be introduced into the para-position first, bromine can be introduced into the ortho-position, and then the 2,6-position group can be converted into vinyl through elimination, addition and other reactions, and 1-bromo-4-iodine-2,6-divinylbenzene can be obtained. However, this approach requires precise design of the structure of the starting material, and fine regulation of the reaction conditions at each step to achieve the ideal yield and purity.
What should I pay attention to when storing and transporting 1-bromo-4-chloro-2,6-difluorobenzene?
1 + -Hg-4 + -Arsenic-2,6-divinylbenzene are all hazardous substances. When storing and transporting, pay careful attention to many matters.
First safety protection. Mercury is a liquid metal that is volatile at room temperature and its vapor is highly toxic. When storing mercury, it must be sealed in a strong, leak-proof container in a cool, well-ventilated place, protected from heat and direct sunlight. When handling mercury, the operator must wear complete protective equipment, such as gas masks, protective gloves and protective clothing, to prevent mercury from contacting the skin and inhaling mercury vapor. Arsenic is a solid poison, mostly in the form of compounds. Arsenic should be stored in a dry, cool and ventilated place, away from fire and heat sources, to prevent its oxidation or reaction. When transporting arsenic, the packaging must be sturdy and have significant warning signs to prevent leakage and accidental contact with others. 2,6-Divinylbenzene is a flammable organic matter. It should be stored in a cool and ventilated warehouse, away from fire and heat sources. The storage temperature should not exceed 37 ° C. Keep the container sealed. When transporting, according to the rules of dangerous goods transportation, with corresponding fire equipment and emergency treatment equipment.
Second, to prevent leakage. If mercury leaks, turn on ventilation equipment as soon as possible, evacuate personnel, and the operator wears protective equipment. Cover the mercury beads with sulfur powder to make them react into mercury sulfide, and then clean up. When arsenic leaks, emergency responders wear full-face masks, dust masks, and gas-proof clothing. Collect it in a dry, clean, covered container with a clean shovel and transfer it to a safe place. 2,6-Divinylbenzene leaks. Quickly evacuate personnel from the leaking contaminated area to a safe area and cut off the fire source. Emergency responders wear self-contained positive pressure breathing apparatus and fire protection clothing to cut off the leakage source as much as possible to prevent it from flowing into restricted spaces such as sewers and drainage ditches. Small leaks are adsorbed or absorbed by sand or other non-combustible materials. A large number of leaks are built into embankments or excavated for containment, covered with foam to reduce steam disasters. Transfer it to a tanker or special collector with an explosion-proof pump, and recycle it or transport it to a waste treatment site for disposal.
Furthermore, marking and recording are also Containers in which these substances are stored must be clearly marked with their names, properties, hazards and emergency treatment methods. Establish detailed records of entry and exit, indicating the variety, quantity, date of entry and exit, and the person handling it for traceability and management.
All of these are for those who should pay attention to the storage and transportation of 1 + -mercury-4 + -arsenic-2,6-divinylbenzene. They must not be negligent to ensure the safety of personnel and the environment.
First safety protection. Mercury is a liquid metal that is volatile at room temperature and its vapor is highly toxic. When storing mercury, it must be sealed in a strong, leak-proof container in a cool, well-ventilated place, protected from heat and direct sunlight. When handling mercury, the operator must wear complete protective equipment, such as gas masks, protective gloves and protective clothing, to prevent mercury from contacting the skin and inhaling mercury vapor. Arsenic is a solid poison, mostly in the form of compounds. Arsenic should be stored in a dry, cool and ventilated place, away from fire and heat sources, to prevent its oxidation or reaction. When transporting arsenic, the packaging must be sturdy and have significant warning signs to prevent leakage and accidental contact with others. 2,6-Divinylbenzene is a flammable organic matter. It should be stored in a cool and ventilated warehouse, away from fire and heat sources. The storage temperature should not exceed 37 ° C. Keep the container sealed. When transporting, according to the rules of dangerous goods transportation, with corresponding fire equipment and emergency treatment equipment.
Second, to prevent leakage. If mercury leaks, turn on ventilation equipment as soon as possible, evacuate personnel, and the operator wears protective equipment. Cover the mercury beads with sulfur powder to make them react into mercury sulfide, and then clean up. When arsenic leaks, emergency responders wear full-face masks, dust masks, and gas-proof clothing. Collect it in a dry, clean, covered container with a clean shovel and transfer it to a safe place. 2,6-Divinylbenzene leaks. Quickly evacuate personnel from the leaking contaminated area to a safe area and cut off the fire source. Emergency responders wear self-contained positive pressure breathing apparatus and fire protection clothing to cut off the leakage source as much as possible to prevent it from flowing into restricted spaces such as sewers and drainage ditches. Small leaks are adsorbed or absorbed by sand or other non-combustible materials. A large number of leaks are built into embankments or excavated for containment, covered with foam to reduce steam disasters. Transfer it to a tanker or special collector with an explosion-proof pump, and recycle it or transport it to a waste treatment site for disposal.
Furthermore, marking and recording are also Containers in which these substances are stored must be clearly marked with their names, properties, hazards and emergency treatment methods. Establish detailed records of entry and exit, indicating the variety, quantity, date of entry and exit, and the person handling it for traceability and management.
All of these are for those who should pay attention to the storage and transportation of 1 + -mercury-4 + -arsenic-2,6-divinylbenzene. They must not be negligent to ensure the safety of personnel and the environment.
What is the approximate market price of 1-bromo-4-chloro-2,6-difluorobenzene?
Wen Ru wants to know the market price of 1 + -bromo-4-fluoro-2,6-divinylbenzene. This compound has its specific use in the chemical industry, but its price often varies due to various factors.
The difficulty of obtaining its raw materials affects the cost and price. If the raw materials are scarce, mining and refining are difficult, the cost will increase and the price will also be high. Furthermore, the complexity of the preparation process is crucial. If cumbersome steps, harsh conditions and special equipment are required, the production cost is high and the price is not cheap.
The market supply and demand situation also affects its price. If there is strong demand for it in many industries, such as electronics, pharmaceutical research and development, etc., and the supply is limited, the price will rise; conversely, if the demand is low and the supply is sufficient, the price may decline.
In addition, the number of manufacturers and the competition status, as well as the requirements of transportation and storage conditions, all affect the price. According to market conditions, the price may fluctuate between tens of yuan and hundreds of yuan per gram. However, this is only an approximation, and the actual price should be determined according to the market conditions at the time of the specific transaction.
The difficulty of obtaining its raw materials affects the cost and price. If the raw materials are scarce, mining and refining are difficult, the cost will increase and the price will also be high. Furthermore, the complexity of the preparation process is crucial. If cumbersome steps, harsh conditions and special equipment are required, the production cost is high and the price is not cheap.
The market supply and demand situation also affects its price. If there is strong demand for it in many industries, such as electronics, pharmaceutical research and development, etc., and the supply is limited, the price will rise; conversely, if the demand is low and the supply is sufficient, the price may decline.
In addition, the number of manufacturers and the competition status, as well as the requirements of transportation and storage conditions, all affect the price. According to market conditions, the price may fluctuate between tens of yuan and hundreds of yuan per gram. However, this is only an approximation, and the actual price should be determined according to the market conditions at the time of the specific transaction.
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