1-Bromo-4-Chloro-2,6-Dimethylbenzene
HS Code |
971999 |
Chemical Formula | C8H8BrCl |
Molecular Weight | 221.506 g/mol |
Appearance | Typically a colorless to light - colored liquid |
Boiling Point | Approximately 235 - 240 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether, and chloroform |
Odor | Characteristic aromatic odor |
As an accredited 1-Bromo-4-Chloro-2,6-Dimethylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 100 g of 1 - bromo - 4 - chloro - 2,6 - dimethylbenzene packaged in a sealed glass bottle. |
Storage | 1 - Bromo - 4 - chloro - 2,6 - dimethylbenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to avoid potential reactions. Label the container clearly for easy identification. |
Shipping | 1 - bromo - 4 - chloro - 2,6 - dimethylbenzene is shipped in sealed, corrosion - resistant containers. It adheres to strict chemical transportation regulations, ensuring safe transit to prevent leakage and environmental or safety hazards. |
Competitive 1-Bromo-4-Chloro-2,6-Dimethylbenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 1-Bromo-4-Chloro-2,6-Dimethylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
This is an organic compound, in its structure, the benzene ring is the group, connected to various substituents. One of the rings is connected to the bromine atom. This bromine is also an element of the halogen group. Its properties are active and often play a key role in organic reactions. At the quaternary position, it is connected to the chlorine atom, and the chlorine and halogen group are of the same genus as bromine, and its properties are also similar. At the two and six positions, each is connected to a methyl group. The methyl group is a group composed of hydrocarbons, and its properties are relatively stable. Therefore, the name of the substance is 1-bromo-4-chloro-2,6-dimethylbenzene, which depends on the position and type of the substituent on its benzene ring. It is based on the general practice of organic chemical nomenclature to accurately describe its structural characteristics, which is different from other compounds and is convenient for academic communication and research.
Under normal temperature and pressure, it is a colorless to light yellow liquid, clear and transparent, like a clear spring, with good visibility and no suspended impurities.
Smell its smell, it has a special aromatic smell, but this fragrance is not pleasant, slightly pungent, and can be diffused in the air. If people smell it, it may feel uncomfortable.
The boiling point is about a certain temperature range, which is determined by factors such as intermolecular forces. Its molecular structure contains bromine, chlorine and other atoms and methyl groups, and the intermolecular force has its own characteristics. The boiling point is about [specific temperature range]. When heated to this temperature range, the substance gradually changes from liquid to gaseous state.
As for the melting point, there is also a specific value. Due to the molecular arrangement and interaction, under [specific temperature], the substance is in a solid state, the structure is relatively regular, and the molecular activity is limited.
Its density is slightly larger than that of water. If it is placed in the same place as water, it can be seen that it sinks to the bottom of the water, such as stone entering the water. This is because of the molecular mass and structure, the mass per unit volume is greater than that of water.
In terms of solubility, it is slightly soluble in water, like oil floating on the water surface, and does not merge. However, in organic solvents, such as ethanol, ether, etc., it has good solubility and can be miscible with it. Due to the principle of similar miscibility, its molecular structure is similar to that of organic solvents, and it can be dispersed evenly.
The physical properties of this compound are of great significance in the fields of organic synthesis, chemical production, etc., providing a basis for the design and operation of related processes.
First of all, the halogen atom bromine and chlorine are on the benzene ring, giving this compound active reactivity. Because the halogen atom has electron-absorbing properties, the electron cloud density of the benzene ring can be reduced. In this way, in the electrophilic substitution reaction, its reactivity is lower than that of benzene. For example, when nitrification occurs, more severe conditions are required to introduce nitro groups.
Furthermore, methyl is a donator group, which is located at the 2,6 position of the benzene ring, which can increase the electron cloud density of the ortho and para-position of the benzene ring. This property interacts with the electron-withdrawing effects of bromine and chlorine. When an electrophilic substitution reaction occurs, the substituents mainly enter the adjacent and para-position of methyl, but are restricted by the electron-withdrawing properties of bromine and chlorine. For example, in Fu-gram alkylation or acylation reactions, the selectivity of the reaction check point is affected by these two factors.
In addition, the bromine and chlorine atoms in this compound can undergo nucleophilic substitution reactions. Under suitable nucleophilic reagents and reaction conditions, bromine or chlorine atoms can be replaced by nucleophilic reagents. For example, in reaction with sodium alcohol, bromine or chlorine atoms can be replaced by alkoxy groups to form corresponding ether compounds; in reaction with ammonia or amine, nitrogen-containing derivatives can be formed.
At the same time, in view of its molecular structure, 1-bromo-4-chloro-2,6-dimethylbenzene may also participate in free radical reactions. In the presence of light or initiators, halogen atoms can be homogenized to produce free radicals, which can then initiate a series of free radical chain reactions, and various organic synthesis products can be derived.
The cover is characterized by its unique structure. There are bromine, chlorine and dimethyl on the benzene ring. These substituents give it special chemical activity and can participate in various chemical reactions to prepare other organic compounds.
In pharmaceutical chemistry, it also has its own shadow. Due to the special activity of the molecule, it can be chemically modified to develop new drugs. Using it as a starting material, by changing the substituent or introducing other functional groups, or compounds with specific pharmacological activities can be prepared for the treatment of diseases.
Furthermore, in the field of materials science, 1-bromo-4-chloro-2,6-dimethylbenzene may participate in the synthesis of polymer materials. After polymerization, it can be combined with other monomers, or it can prepare polymers with special properties, such as affecting the solubility, thermal stability, mechanical properties of materials, etc., and then applied to the manufacture of electronic, optical and other materials.
In short, 1-bromo-4-chloro-2,6-dimethylbenzene has important uses in many fields such as chemicals, drugs, and materials, providing an important material basis for the development of organic synthesis and related industries.
First, start with 2,6-dimethylphenol. React it with brominating reagents, such as bromine (Br ²), in a suitable solvent (such as dichloromethane) and at low temperature, the hydrogen of the phenolic hydroxyl ortho-position can be replaced by bromine to obtain 2-bromo-6-methylphenol. Then treated with suitable chlorination reagents, such as sulfoxide chloride (SOCl -2) or phosphorus oxychloride (POCl ²), the phenolic hydroxyl group can be converted into chlorine atoms, and then the target product 1-bromo-4-chloro-2,6-dimethylbenzene can be obtained. The advantage of this path is that the starting materials are easily available, and the reaction steps are relatively clear. However, the activity of phenolic compounds is high, and the reaction conditions need to be carefully controlled to prevent overreaction.
Second, m-xylene is used as the starting material. First, 4-chloro-m-xylene can be obtained by chlorination reagents, such as chlorine gas (Cl ²), under the action of light or catalysts (such as FeCl ²). Following the reaction with brominating reagents, such as N-bromosuccinimide (NBS), in the presence of initiators (such as benzoyl peroxide), bromine atoms can be introduced at the position adjacent to methyl to obtain 1-bromo-4-chloro-2,6-dimethylbenzene. The raw materials of this method are economical and easy to obtain, and the operation is relatively convenient. Only the selectivity of chlorination and bromination reactions needs to be paid attention to to to avoid excessive by-products.
Or, 2,6-dimethylaniline is used as the starting material. First, the diazotization reaction is carried out, and the amino group is converted into diazonium salt by the interaction of sodium nitrite (NaNO ²) with hydrochloric acid. Then the Sandmeier reaction with copper bromide (CuBr) or cuprous chloride (CuCl) can introduce bromine atoms and chlorine atoms respectively to achieve the synthesis target. This path can accurately introduce halogen atoms, and the product purity is high. However, the diazotization reaction is more dangerous, and the reaction operation requirements are strict, so it needs to be treated with caution.
All these synthetic methods have their own advantages and disadvantages. In practice, the appropriate synthesis path is carefully selected according to many factors such as the availability of raw materials, cost considerations, ease of control of reaction conditions, and product purity requirements.

Scan to WhatsApp