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1-Bromo-4-Chloro-2-Fluorobenzene 97%
Linshang Chemical
|
HS Code |
613140 |
| Name | 1-Bromo-4-Chloro-2-Fluorobenzene 97% |
| Chemical Formula | C6H3BrClF |
| Molecular Weight | 209.44 |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 193 - 195 °C |
| Density | 1.736 g/mL at 25 °C |
| Solubility | Insoluble in water, soluble in organic solvents like ethanol, ether |
| Flash Point | 78 °C |
| Purity | 97% |
As an accredited 1-Bromo-4-Chloro-2-Fluorobenzene 97% factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 97% 1 - bromo - 4 - chloro - 2 - fluorobenzene in a sealed chemical - grade bottle. |
| Storage | 1 - Bromo - 4 - chloro - 2 - fluorobenzene (97%) should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive chemicals. Avoid storage in areas prone to flooding or high humidity to maintain its quality. |
| Shipping | 1 - bromo - 4 - chloro - 2 - fluorobenzene (97%) is shipped in accordance with strict chemical regulations. Packed securely in appropriate containers, it's transported by carriers experienced in handling hazardous chemicals, ensuring safe delivery. |
Competitive 1-Bromo-4-Chloro-2-Fluorobenzene 97% prices that fit your budget—flexible terms and customized quotes for every order.
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What are the main uses of 1-bromo-4-chloro-2-fluorobenzene 97%?
1-Bromo-4-chloro-2-fluorobenzene, with a content of 97%, is widely used. In the field of organic synthesis, this compound is often a key raw material.
Looking at the history of organic synthesis in the past, chemists often rely on such halogenated aromatics to construct complex organic molecular structures. In 1-bromo-4-chloro-2-fluorobenzene, three halogen atoms of bromine, chlorine and fluorine are active and can participate in various chemical reactions.
In terms of nucleophilic substitution, due to the existence of halogen atoms, it can interact with a variety of nucleophilic reagents. For example, when reacting with reagents containing nucleophilic groups such as nitrogen, oxygen, and sulfur, different functional groups can be introduced, and then organic compounds with diverse structures can be derived. This is crucial in the creation of novel drug molecules and the synthesis of intermediates of functional materials.
In the field of materials science, using this as the starting material, through a specific reaction path, materials with special optoelectronic properties can be prepared. In electronic devices, such materials may be used as organic semiconductors to help improve the performance of electronic components.
Furthermore, in the field of pesticide chemistry, it is also used. After chemical modification, pesticide ingredients with high insecticidal and bactericidal activities can be prepared. Through the relationship between molecular structure and biological activity, pesticide products with high selectivity and low environmental hazard to target organisms can be precisely designed. Therefore, 1-bromo-4-chloro-2-fluorobenzene has shown important uses in many fields due to its unique chemical structure.
Looking at the history of organic synthesis in the past, chemists often rely on such halogenated aromatics to construct complex organic molecular structures. In 1-bromo-4-chloro-2-fluorobenzene, three halogen atoms of bromine, chlorine and fluorine are active and can participate in various chemical reactions.
In terms of nucleophilic substitution, due to the existence of halogen atoms, it can interact with a variety of nucleophilic reagents. For example, when reacting with reagents containing nucleophilic groups such as nitrogen, oxygen, and sulfur, different functional groups can be introduced, and then organic compounds with diverse structures can be derived. This is crucial in the creation of novel drug molecules and the synthesis of intermediates of functional materials.
In the field of materials science, using this as the starting material, through a specific reaction path, materials with special optoelectronic properties can be prepared. In electronic devices, such materials may be used as organic semiconductors to help improve the performance of electronic components.
Furthermore, in the field of pesticide chemistry, it is also used. After chemical modification, pesticide ingredients with high insecticidal and bactericidal activities can be prepared. Through the relationship between molecular structure and biological activity, pesticide products with high selectivity and low environmental hazard to target organisms can be precisely designed. Therefore, 1-bromo-4-chloro-2-fluorobenzene has shown important uses in many fields due to its unique chemical structure.
1-bromo-4-chloro-2-fluorobenzene 97% of the physical properties
1 - bromo - 4 - chloro - 2 - fluorobenzene is an organic compound containing bromine, chlorine, fluorine atoms and benzene ring structure. This substance is 97% pure and has the following physical properties:
- ** Properties **: Under normal conditions, it may be a colorless to light yellow liquid, and pure organic compounds often have such an appearance. Because the molecule contains halogen atoms, the structure has certain symmetry and stability, resulting in a specific aggregate state.
- ** Boiling point **: Its boiling point or due to the interaction of halogen atoms and benzene rings is in a specific range. Halogen atoms increase the intermolecular force, causing the boiling point to rise, or between 170 and 200 ° C. The specific value is accurately determined according to the experiment.
- ** Melting point **: The melting point is affected by intermolecular forces and arrangements. The structural regularity of the compound and the interaction of halogen atoms make the melting point have a specific value, or between - 20 and 0 ° C, which can be accurately determined by experiments.
- ** Density **: The density is greater than that of water, and the molecular weight increases due to the large atomic weight of halogen atoms, so that the unit volume mass is greater than that of water, or between 1.6 and 1.8 g/cm ³.
- ** Solubility **: Slightly soluble in water, because water is a polar molecule, although the compound contains polar halogen atoms, the benzene ring is a non-polar structure, the overall polarity is weak, and the force with water is small. Soluble in common organic solvents, such as ethanol, ether, dichloromethane, etc. Due to the principle of similar miscibility, organic solvents match the polarity of the compound or can interact with molecules.
- ** Odor **: Or has a special odor, organic halides often have irritating or special odor, and need to be operated according to specifications when smelling, because it may be toxic and harmful.
- ** Properties **: Under normal conditions, it may be a colorless to light yellow liquid, and pure organic compounds often have such an appearance. Because the molecule contains halogen atoms, the structure has certain symmetry and stability, resulting in a specific aggregate state.
- ** Boiling point **: Its boiling point or due to the interaction of halogen atoms and benzene rings is in a specific range. Halogen atoms increase the intermolecular force, causing the boiling point to rise, or between 170 and 200 ° C. The specific value is accurately determined according to the experiment.
- ** Melting point **: The melting point is affected by intermolecular forces and arrangements. The structural regularity of the compound and the interaction of halogen atoms make the melting point have a specific value, or between - 20 and 0 ° C, which can be accurately determined by experiments.
- ** Density **: The density is greater than that of water, and the molecular weight increases due to the large atomic weight of halogen atoms, so that the unit volume mass is greater than that of water, or between 1.6 and 1.8 g/cm ³.
- ** Solubility **: Slightly soluble in water, because water is a polar molecule, although the compound contains polar halogen atoms, the benzene ring is a non-polar structure, the overall polarity is weak, and the force with water is small. Soluble in common organic solvents, such as ethanol, ether, dichloromethane, etc. Due to the principle of similar miscibility, organic solvents match the polarity of the compound or can interact with molecules.
- ** Odor **: Or has a special odor, organic halides often have irritating or special odor, and need to be operated according to specifications when smelling, because it may be toxic and harmful.
1-bromo-4-chloro-2-fluorobenzene 97% chemically stable?
1-Bromo-4-chloro-2-fluorobenzene is an organic compound containing bromine, chlorine, fluorine and other halogen atoms on the benzene ring. This compound is 97% pure and has generally stable chemical properties. The benzene ring has a conjugated system, which imparts certain structural stability.
From the perspective of halogen atoms, although the activity of halogen atoms is different, under normal conditions, without specific conditions, such as suitable temperatures, catalysts or specific reagents, halogen atoms are difficult to react. The stability of this compound can be analogous to that of the substances described in "Tiangong Kai", such as certain minerals or metals. If there is no external force in the natural environment, it can maintain its inherent form for a long time.
When encountering strong nucleophilic reagents or high temperatures, halogen atoms will participate in the reaction. For example, in the nucleophilic substitution reaction, the reagents attack the carbon connected to the halogen atoms, and the halogen atoms leave to form new compounds. This change can be compared to the process of ore being converted into metals through a specific smelting process in Tiangong Kaiwu, which occurs qualitative change due to changes in external conditions.
However, under normal storage and conventional environments, 1-bromo-4-chloro-2-fluorobenzene with a purity of 97% is chemically stable and does not react spontaneously. Just like many stable materials recorded in Tiangong Kaiwu, it can maintain its original characteristics when not treated by specific processes.
From the perspective of halogen atoms, although the activity of halogen atoms is different, under normal conditions, without specific conditions, such as suitable temperatures, catalysts or specific reagents, halogen atoms are difficult to react. The stability of this compound can be analogous to that of the substances described in "Tiangong Kai", such as certain minerals or metals. If there is no external force in the natural environment, it can maintain its inherent form for a long time.
When encountering strong nucleophilic reagents or high temperatures, halogen atoms will participate in the reaction. For example, in the nucleophilic substitution reaction, the reagents attack the carbon connected to the halogen atoms, and the halogen atoms leave to form new compounds. This change can be compared to the process of ore being converted into metals through a specific smelting process in Tiangong Kaiwu, which occurs qualitative change due to changes in external conditions.
However, under normal storage and conventional environments, 1-bromo-4-chloro-2-fluorobenzene with a purity of 97% is chemically stable and does not react spontaneously. Just like many stable materials recorded in Tiangong Kaiwu, it can maintain its original characteristics when not treated by specific processes.
1-bromo-4-chloro-2-fluorobenzene 97% of the production process
1-Bromo-4-chloro-2-fluorobenzene is an organic compound containing bromine, chlorine, and fluorine atoms on the benzene ring. Its 97% purity production process is complex and requires multiple steps, as detailed below.
The starting material is p-chlorofluorobenzene, which is the basis for synthesis. The first step of the reaction is bromination, in which p-chlorofluorobenzene is co-placed in a reactor with a brominating reagent, such as liquid bromine or N-bromosuccinimide (NBS). Taking liquid bromine as an example, iron or iron tribromide are often used as catalysts. During the reaction, liquid bromine and p-chlorofluorobenzene are catalyzed by a catalyst, and bromine atoms replace hydrogen atoms at specific positions in the benzene ring. Due to the influence of chlorine and fluorine atoms on the electron cloud distribution in the benzene ring, bromine atoms mainly replace specific positions to generate the crude product of 1-bromo-4-chloro-2-fluorobenzene.
The reaction conditions in this step are quite critical, and the temperature needs to be precisely controlled, generally between low temperature and moderate temperature, such as 0-50 ° C. If the temperature is too high, the side reaction will be easy to produce and polybrominated products will be formed; if the temperature is too low, the reaction rate will be slow and the production efficiency will be low. At the same time, the catalyst dosage also needs to be finely adjusted. If the dosage is too
After the crude product is formed, it needs to be separated and purified. First, water-soluble impurities, such as hydrobromic acid formed by the reaction, are removed by washing with water. Then, organic solvent extraction is used to select organic solvents that are insoluble with water and have good solubility to the product, such as dichloromethane, ethyl acetate, etc. After extraction, the organic phase is dried with anhydrous sodium sulfate or magnesium sulfate to remove residual water.
After drying, the organic phase is further purified by distillation. According to the difference in boiling points between the product and the impurities, the product can be evaporated by precise temperature control, and the fractions in a specific temperature range can be collected to obtain higher purity 1-bromo-4-chloro-2-fluorobenzene. However, during the distillation process, factors such as vacuum degree and heating rate all affect the purity and yield of the product.
is a high purity of 97%, or multiple distillations or supplemented by column chromatography are required. During column chromatography, suitable stationary phase (such as silica gel) and mobile phase (such as petroleum ether and ethyl acetate mixture) are selected, and the product and impurities are separated by the difference in partition coefficients between the stationary phase and the mobile phase. After this series of steps, 1-bromo-4-chloro-2-fluorobenzene with a purity of 97% can be obtained.
The starting material is p-chlorofluorobenzene, which is the basis for synthesis. The first step of the reaction is bromination, in which p-chlorofluorobenzene is co-placed in a reactor with a brominating reagent, such as liquid bromine or N-bromosuccinimide (NBS). Taking liquid bromine as an example, iron or iron tribromide are often used as catalysts. During the reaction, liquid bromine and p-chlorofluorobenzene are catalyzed by a catalyst, and bromine atoms replace hydrogen atoms at specific positions in the benzene ring. Due to the influence of chlorine and fluorine atoms on the electron cloud distribution in the benzene ring, bromine atoms mainly replace specific positions to generate the crude product of 1-bromo-4-chloro-2-fluorobenzene.
The reaction conditions in this step are quite critical, and the temperature needs to be precisely controlled, generally between low temperature and moderate temperature, such as 0-50 ° C. If the temperature is too high, the side reaction will be easy to produce and polybrominated products will be formed; if the temperature is too low, the reaction rate will be slow and the production efficiency will be low. At the same time, the catalyst dosage also needs to be finely adjusted. If the dosage is too
After the crude product is formed, it needs to be separated and purified. First, water-soluble impurities, such as hydrobromic acid formed by the reaction, are removed by washing with water. Then, organic solvent extraction is used to select organic solvents that are insoluble with water and have good solubility to the product, such as dichloromethane, ethyl acetate, etc. After extraction, the organic phase is dried with anhydrous sodium sulfate or magnesium sulfate to remove residual water.
After drying, the organic phase is further purified by distillation. According to the difference in boiling points between the product and the impurities, the product can be evaporated by precise temperature control, and the fractions in a specific temperature range can be collected to obtain higher purity 1-bromo-4-chloro-2-fluorobenzene. However, during the distillation process, factors such as vacuum degree and heating rate all affect the purity and yield of the product.
is a high purity of 97%, or multiple distillations or supplemented by column chromatography are required. During column chromatography, suitable stationary phase (such as silica gel) and mobile phase (such as petroleum ether and ethyl acetate mixture) are selected, and the product and impurities are separated by the difference in partition coefficients between the stationary phase and the mobile phase. After this series of steps, 1-bromo-4-chloro-2-fluorobenzene with a purity of 97% can be obtained.
1-bromo-4-chloro-2-fluorobenzene 97% What are the precautions in storage and transportation
1 - bromo - 4 - chloro - 2 - fluorobenzene is an organic compound with a content of 97%. There are many precautions to be paid attention to during storage and transportation.
Let's talk about storage first. This compound may be more active in nature and needs to be placed in a cool, dry and well-ventilated place. Due to high temperature and humid environment, it is very likely to cause its deterioration or chemical reaction. Warehouse temperature should be strictly controlled, not too high, so as to avoid internal structural changes or even danger caused by the substance due to heat. And should be kept away from fire and heat sources, because it may be flammable, in case of open flames and hot topics, there is a risk of combustion and explosion.
Furthermore, it needs to be stored separately from oxidizing agents, acids, alkalis and other substances. The chemical properties of this compound determine that contact with the above substances can easily cause chemical reactions, or cause product quality damage, or cause safety accidents. The storage place should also be clearly marked with key information such as its name, nature, and hazard characteristics, so that it can be accessed and managed, and it is convenient for relevant personnel to quickly know the countermeasures in case of emergency.
As for transportation, it is necessary to ensure that the packaging is complete and well sealed. The packaging material must be able to withstand a certain amount of external force to avoid packaging damage due to collision, vibration, etc. during transportation, and then the compound leakage. The transportation vehicle must also meet relevant safety standards and be equipped with corresponding fire equipment and leakage emergency treatment equipment. During transportation, route planning should not be ignored. Sensitive areas such as densely populated areas and water sources should be avoided as much as possible to prevent accidental leakage from causing serious harm to the public and the environment. Escorts must undergo professional training, be familiar with the properties of the compound and emergency treatment methods, pay close attention to the status of the goods during transportation, and dispose of it immediately if any abnormalities are detected.
Let's talk about storage first. This compound may be more active in nature and needs to be placed in a cool, dry and well-ventilated place. Due to high temperature and humid environment, it is very likely to cause its deterioration or chemical reaction. Warehouse temperature should be strictly controlled, not too high, so as to avoid internal structural changes or even danger caused by the substance due to heat. And should be kept away from fire and heat sources, because it may be flammable, in case of open flames and hot topics, there is a risk of combustion and explosion.
Furthermore, it needs to be stored separately from oxidizing agents, acids, alkalis and other substances. The chemical properties of this compound determine that contact with the above substances can easily cause chemical reactions, or cause product quality damage, or cause safety accidents. The storage place should also be clearly marked with key information such as its name, nature, and hazard characteristics, so that it can be accessed and managed, and it is convenient for relevant personnel to quickly know the countermeasures in case of emergency.
As for transportation, it is necessary to ensure that the packaging is complete and well sealed. The packaging material must be able to withstand a certain amount of external force to avoid packaging damage due to collision, vibration, etc. during transportation, and then the compound leakage. The transportation vehicle must also meet relevant safety standards and be equipped with corresponding fire equipment and leakage emergency treatment equipment. During transportation, route planning should not be ignored. Sensitive areas such as densely populated areas and water sources should be avoided as much as possible to prevent accidental leakage from causing serious harm to the public and the environment. Escorts must undergo professional training, be familiar with the properties of the compound and emergency treatment methods, pay close attention to the status of the goods during transportation, and dispose of it immediately if any abnormalities are detected.
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