Linshang Chemical
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1-Bromo-4-Chloro-2-Iodobenzene
Linshang Chemical
|
HS Code |
597512 |
| Chemical Formula | C6H3BrClI |
| Molecular Weight | 329.35 |
| Appearance | Solid (usually a white to off - white powder) |
| Melting Point | Data may vary, typically in a certain temperature range |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Density | Data may be available in specific references |
| Hazard Class | May be classified as a hazardous chemical due to halogen content |
As an accredited 1-Bromo-4-Chloro-2-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 g of 1 - bromo - 4 - chloro - 2 - iodobenzene packaged in a sealed glass bottle. |
| Storage | 1 - Bromo - 4 - chloro - 2 - iodobenzene should be stored in a cool, dry, well - ventilated area, away from sources of heat, ignition, and oxidizing agents. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials like glass, to prevent leakage and exposure to air and moisture. Label the storage container clearly with its name and relevant hazard information. |
| Shipping | 1 - bromo - 4 - chloro - 2 - iodobenzene is shipped in well - sealed, corrosion - resistant containers. It's transported under proper temperature control, following strict regulations for handling hazardous chemicals to ensure safety during transit. |
Competitive 1-Bromo-4-Chloro-2-Iodobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Bromo-4-Chloro-2-Iodobenzene in China?
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As a leading 1-Bromo-4-Chloro-2-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 1 - bromo - 4 - chloro - 2 - iodobenzene
1 + -Bromo-4-chloro-2-iodobenzene is also an organic compound. Its chemical properties are particularly important and are related to many fields such as organic synthesis.
In this compound, the presence of bromine, chlorine and iodine halogen atoms endows it with unique reactivity. Bromine, chlorine and iodine atoms have different electronegativity and atomic radii. This difference affects the electron cloud distribution and spatial structure of the molecule, which in turn affects its chemical behavior.
In nucleophilic substitution reactions, halogen atoms can act as leaving groups. Usually, iodine atoms are easy to leave due to their large atomic radius and relatively small C-I bond energy, so the iodine atoms of this compound are easily replaced by nucleophiles under appropriate conditions. Although the departure ability of bromine and chlorine atoms is slightly inferior to that of iodine, they can also participate in nucleophilic substitution under suitable conditions, and the different reactivity of different halogen atoms can be used to selectively synthesize organic products with specific structures.
And because its molecule contains multiple halogen atoms, it can participate in metal-catalyzed cross-coupling reactions. For example, under palladium catalysis, it can be coupled with reagents containing boron and zinc to form carbon-carbon bonds, which is an important means to grow carbon chains and build complex molecular structures in organic synthesis.
Furthermore, the chemical properties of the compound are also affected by the electron effect of the benzene ring. The benzene ring is a conjugated system with a certain degree of electron delocalization. The halogen atom is attached to the benzene ring, and the electron cloud density of the benzene ring can be changed due to the induction effect and the conjugation effect. The halogen atom is an electron-withdrawing group, which reduces the electron cloud density of the benzene ring, weakens the electrophilic substitution reaction activity of the benzene ring, and the reaction check point is also restricted by the localization effect of the halogen atom. For example, bromine, chlorine, and iodine are all ortho-sites. When the electrophilic reagent attacks the benzene ring, it mainly attacks the ortho and para-sites of the hal
In summary, the interaction between 1 + -bromo-4-chloro-2-iodobenzene halogen atoms and benzene rings exhibits rich and diverse chemical properties, which are widely used in the field of organic synthetic chemistry. It is an important starting material and intermediate for the creation of various organic compounds.
In this compound, the presence of bromine, chlorine and iodine halogen atoms endows it with unique reactivity. Bromine, chlorine and iodine atoms have different electronegativity and atomic radii. This difference affects the electron cloud distribution and spatial structure of the molecule, which in turn affects its chemical behavior.
In nucleophilic substitution reactions, halogen atoms can act as leaving groups. Usually, iodine atoms are easy to leave due to their large atomic radius and relatively small C-I bond energy, so the iodine atoms of this compound are easily replaced by nucleophiles under appropriate conditions. Although the departure ability of bromine and chlorine atoms is slightly inferior to that of iodine, they can also participate in nucleophilic substitution under suitable conditions, and the different reactivity of different halogen atoms can be used to selectively synthesize organic products with specific structures.
And because its molecule contains multiple halogen atoms, it can participate in metal-catalyzed cross-coupling reactions. For example, under palladium catalysis, it can be coupled with reagents containing boron and zinc to form carbon-carbon bonds, which is an important means to grow carbon chains and build complex molecular structures in organic synthesis.
Furthermore, the chemical properties of the compound are also affected by the electron effect of the benzene ring. The benzene ring is a conjugated system with a certain degree of electron delocalization. The halogen atom is attached to the benzene ring, and the electron cloud density of the benzene ring can be changed due to the induction effect and the conjugation effect. The halogen atom is an electron-withdrawing group, which reduces the electron cloud density of the benzene ring, weakens the electrophilic substitution reaction activity of the benzene ring, and the reaction check point is also restricted by the localization effect of the halogen atom. For example, bromine, chlorine, and iodine are all ortho-sites. When the electrophilic reagent attacks the benzene ring, it mainly attacks the ortho and para-sites of the hal
In summary, the interaction between 1 + -bromo-4-chloro-2-iodobenzene halogen atoms and benzene rings exhibits rich and diverse chemical properties, which are widely used in the field of organic synthetic chemistry. It is an important starting material and intermediate for the creation of various organic compounds.
What are the main uses of 1 - bromo - 4 - chloro - 2 - iodobenzene
1-Bromo-4-chloro-2-iodobenzene is also an organic compound. It has a wide range of uses and plays an important role in the field of organic synthesis.
First, it can be used as a raw material for pharmaceutical synthesis. The rise of medicine depends on many organic compounds to make good medicines. 1-Bromo-4-chloro-2-iodobenzene has a unique structure and can be chemically modified to introduce specific groups to synthesize molecules with pharmacological activity. For example, some antibacterial and antiviral drugs, the synthesis path or involved in this substance, with it as the starting material, through multi-step reaction, to obtain the required active ingredient.
Second, it is also very useful in the synthesis of pesticides. With the prosperity of agriculture, pesticides are a powerful tool to protect seedlings and eliminate pests. 1-Bromo-4-chloro-2-iodobenzene can be used as a key building block for the construction of pesticide molecules. Through ingenious reaction design, pesticide products that have high efficiency in killing pests and have little impact on the environment can be produced, ensuring the safety of crops and promoting the hope of harvest.
Third, in the field of materials science, it also has its own application. With the development of science and technology, the demand for new materials is increasing. 1-Bromo-4-chloro-2-iodobenzene can participate in the preparation of polymers or functional materials. After polymerization or compounding with other materials, it can endow materials with special electrical and optical properties, such as for the preparation of materials with specific photoelectric properties, to meet the needs of electronic devices, optical instruments and other fields.
In short, although 1-bromo-4-chloro-2-iodobenzene is small, it is indispensable in the fields of medicine, pesticides, materials, etc., promoting the progress and development of various industries.
First, it can be used as a raw material for pharmaceutical synthesis. The rise of medicine depends on many organic compounds to make good medicines. 1-Bromo-4-chloro-2-iodobenzene has a unique structure and can be chemically modified to introduce specific groups to synthesize molecules with pharmacological activity. For example, some antibacterial and antiviral drugs, the synthesis path or involved in this substance, with it as the starting material, through multi-step reaction, to obtain the required active ingredient.
Second, it is also very useful in the synthesis of pesticides. With the prosperity of agriculture, pesticides are a powerful tool to protect seedlings and eliminate pests. 1-Bromo-4-chloro-2-iodobenzene can be used as a key building block for the construction of pesticide molecules. Through ingenious reaction design, pesticide products that have high efficiency in killing pests and have little impact on the environment can be produced, ensuring the safety of crops and promoting the hope of harvest.
Third, in the field of materials science, it also has its own application. With the development of science and technology, the demand for new materials is increasing. 1-Bromo-4-chloro-2-iodobenzene can participate in the preparation of polymers or functional materials. After polymerization or compounding with other materials, it can endow materials with special electrical and optical properties, such as for the preparation of materials with specific photoelectric properties, to meet the needs of electronic devices, optical instruments and other fields.
In short, although 1-bromo-4-chloro-2-iodobenzene is small, it is indispensable in the fields of medicine, pesticides, materials, etc., promoting the progress and development of various industries.
What is the synthesis of 1 - bromo - 4 - chloro - 2 - iodobenzene
The synthesis of 1 + -bromo-4-chloro-2-iodobenzene is an important topic in organic synthetic chemistry. To obtain this compound, the following steps can be followed.
Starting material, select a suitable benzene derivative. P-chlorobrobenzene is commonly used as the starting material, because its structure already contains bromine and chlorine atoms, which can reduce the reaction steps. First, p-chlorobrobenzene is applied to a specific reagent, which needs to be able to guide the iodine atom to a specific position in the benzene ring.
In the reaction system, iodine-containing reagents, such as iodine element (I ²), can be introduced, and a suitable catalyst can be matched. This catalyst is often a transition metal catalyst, such as a copper salt catalyst. Copper salts can promote the nucleophilic substitution reaction between iodine atoms and benzene rings. The reaction environment needs to be properly controlled, and temperature and solvent are all key factors. Too high or too low temperature can affect the reaction rate and selectivity. Usually, the reaction can be carried out under moderate heating, such as in an organic solvent, heated to between 50-80 degrees Celsius. The organic solvent can be selected as N, N-dimethylformamide (DMF) or dimethyl sulfoxide (DMSO). Such solvents can effectively dissolve the reactants and promote the reaction.
In addition, in order to ensure the smooth reaction, the reaction system needs to be maintained in an anhydrous and oxygen-free environment. Because water and oxygen can interfere with the reaction process, side reactions increase. The reaction vessel can be dried before the reaction, and an inert gas such as nitrogen or argon can be introduced during the reaction to remove air from the system.
After the reaction is completed, the product needs to be separated and purified. Column chromatography can be used to select a suitable silica gel column and elute with eluents of different polarities, so that the target product 1 + -bromo-4-chloro-2-iodobenzene can be separated from the reaction mixture to obtain a high-purity product. This is a common method for synthesizing 1 + -bromo-4-chloro-2-iodobenzene. After careful control of each step, the product with ideal yield and purity can be obtained.
Starting material, select a suitable benzene derivative. P-chlorobrobenzene is commonly used as the starting material, because its structure already contains bromine and chlorine atoms, which can reduce the reaction steps. First, p-chlorobrobenzene is applied to a specific reagent, which needs to be able to guide the iodine atom to a specific position in the benzene ring.
In the reaction system, iodine-containing reagents, such as iodine element (I ²), can be introduced, and a suitable catalyst can be matched. This catalyst is often a transition metal catalyst, such as a copper salt catalyst. Copper salts can promote the nucleophilic substitution reaction between iodine atoms and benzene rings. The reaction environment needs to be properly controlled, and temperature and solvent are all key factors. Too high or too low temperature can affect the reaction rate and selectivity. Usually, the reaction can be carried out under moderate heating, such as in an organic solvent, heated to between 50-80 degrees Celsius. The organic solvent can be selected as N, N-dimethylformamide (DMF) or dimethyl sulfoxide (DMSO). Such solvents can effectively dissolve the reactants and promote the reaction.
In addition, in order to ensure the smooth reaction, the reaction system needs to be maintained in an anhydrous and oxygen-free environment. Because water and oxygen can interfere with the reaction process, side reactions increase. The reaction vessel can be dried before the reaction, and an inert gas such as nitrogen or argon can be introduced during the reaction to remove air from the system.
After the reaction is completed, the product needs to be separated and purified. Column chromatography can be used to select a suitable silica gel column and elute with eluents of different polarities, so that the target product 1 + -bromo-4-chloro-2-iodobenzene can be separated from the reaction mixture to obtain a high-purity product. This is a common method for synthesizing 1 + -bromo-4-chloro-2-iodobenzene. After careful control of each step, the product with ideal yield and purity can be obtained.
1 - bromo - 4 - chloro - 2 - iodobenzene What are the precautions during storage
1 + -Bromo-4-chloro-2-iodobenzene is also an organic compound. During storage, there are several things to pay attention to.
First, avoid heat and open flames. This compound is heated or exposed to open flames, or causes combustion, or even the risk of explosion. Therefore, when stored in a cool, ventilated warehouse, away from fire and heat sources, the storage temperature should not exceed 30 ° C.
Second, moisture-proof. It is in a humid environment, or deterioration, affecting quality and performance. It must be stored in a dry place, and the packaging must be sealed to prevent moisture intrusion.
Furthermore, store separately from oxidizing agents, strong alkalis, etc. This compound comes into contact with an oxidizing agent, or reacts violently; coexists with a strong alkali, or causes a chemical reaction, which impairs its properties.
In addition, the storage place should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. If there is a leak, it can be disposed of according to its characteristics by appropriate methods.
In short, proper storage of 1 + -bromo-4-chloro-2-iodobenzene is related to safety and quality, and must not be ignored. It must be done in accordance with norms and requirements to prevent problems before they occur.
First, avoid heat and open flames. This compound is heated or exposed to open flames, or causes combustion, or even the risk of explosion. Therefore, when stored in a cool, ventilated warehouse, away from fire and heat sources, the storage temperature should not exceed 30 ° C.
Second, moisture-proof. It is in a humid environment, or deterioration, affecting quality and performance. It must be stored in a dry place, and the packaging must be sealed to prevent moisture intrusion.
Furthermore, store separately from oxidizing agents, strong alkalis, etc. This compound comes into contact with an oxidizing agent, or reacts violently; coexists with a strong alkali, or causes a chemical reaction, which impairs its properties.
In addition, the storage place should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. If there is a leak, it can be disposed of according to its characteristics by appropriate methods.
In short, proper storage of 1 + -bromo-4-chloro-2-iodobenzene is related to safety and quality, and must not be ignored. It must be done in accordance with norms and requirements to prevent problems before they occur.
What are the environmental effects of 1 - bromo - 4 - chloro - 2 - iodobenzene
1 + -Bromo-4-chloro-2-iodobenzene is a genus of organohalogenated aromatic hydrocarbons. In the environment, its impact is quite wide.
This compound has a certain stability and is difficult to degrade quickly. It enters the natural environment or persists in soil and water bodies for a long time. In soil, it can gradually penetrate, affecting soil texture and microbial community. Microorganisms depend on soil for survival, and their balance is broken, or soil fertility is reduced, which is unfavorable to plant growth and development.
It is also harmful in water bodies. If it flows into rivers, lakes and seas, it can cause water quality to deteriorate. Aquatic organisms are sensitive to it, or the number of some species decreases, breaking the balance of aquatic ecosystems. And it may be enriched through the food chain, small fish accidentally eat plankton containing this substance, big fish eat small fish, and eventually humans eat fish. This substance accumulates in the human body and damages human health, such as affecting the nervous system and reproductive system.
In the atmosphere, although its content is small, it enters through volatilization and other processes, or reacts with other pollutants to generate new harmful substances, affects air quality, and also has adverse effects on human respiration.
In short, 1-bromo-4-chloro-2-iodobenzene is harmful to the environment. When treated with caution, its emissions should be controlled to reduce its adverse effects on the environment and humans.
This compound has a certain stability and is difficult to degrade quickly. It enters the natural environment or persists in soil and water bodies for a long time. In soil, it can gradually penetrate, affecting soil texture and microbial community. Microorganisms depend on soil for survival, and their balance is broken, or soil fertility is reduced, which is unfavorable to plant growth and development.
It is also harmful in water bodies. If it flows into rivers, lakes and seas, it can cause water quality to deteriorate. Aquatic organisms are sensitive to it, or the number of some species decreases, breaking the balance of aquatic ecosystems. And it may be enriched through the food chain, small fish accidentally eat plankton containing this substance, big fish eat small fish, and eventually humans eat fish. This substance accumulates in the human body and damages human health, such as affecting the nervous system and reproductive system.
In the atmosphere, although its content is small, it enters through volatilization and other processes, or reacts with other pollutants to generate new harmful substances, affects air quality, and also has adverse effects on human respiration.
In short, 1-bromo-4-chloro-2-iodobenzene is harmful to the environment. When treated with caution, its emissions should be controlled to reduce its adverse effects on the environment and humans.
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