Linshang Chemical
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1-Bromo-4-Chloro-2-Methylbenzene
Linshang Chemical
|
HS Code |
995277 |
| Chemical Formula | C7H6BrCl |
| Molar Mass | 207.48 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 214 - 216 °C |
| Density | 1.52 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether, etc. |
| Flash Point | 92 °C |
| Odor | Characteristic aromatic odor |
As an accredited 1-Bromo-4-Chloro-2-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 g of 1 - bromo - 4 - chloro - 2 - methylbenzene packaged in a sealed glass bottle. |
| Storage | 1 - Bromo - 4 - chloro - 2 - methylbenzene should be stored in a cool, well - ventilated area away from heat sources and open flames. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reactive chemicals, and foodstuffs to prevent potential reactions and contamination. |
| Shipping | 1 - bromo - 4 - chloro - 2 - methylbenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, with proper labeling indicating its nature for safe transportation. |
Competitive 1-Bromo-4-Chloro-2-Methylbenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Bromo-4-Chloro-2-Methylbenzene in China?
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As a leading 1-Bromo-4-Chloro-2-Methylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 1-bromo-4-chloro-2-methylbenzene?
The physical properties of 1 + -ether-4 + -alkane-2 + -methylnaphthalene are as follows:
This compound is mostly liquid at room temperature, but it also depends on the specific molecular structure and surrounding environmental conditions. Looking at its color, when it is pure, it is often colorless and transparent. If it contains impurities, it may change color. Its smell has a slightly special aromatic aroma. Although it is not pungent and unpleasant, it is also unique and can be used for identification.
In terms of density, it is usually slightly lighter than water, so if mixed with water, it can float on the water surface. This property is quite useful in many practical applications and separation operations. Its boiling point is closely related to the intermolecular force. Due to the structure of the molecule, the intermolecular force is different, and the boiling point is also different. It is roughly within a certain temperature range and needs to be accurately determined by experiments.
In terms of solubility, in organic solvents such as ethanol and ether, it often shows good solubility. Due to the similar miscibility, its molecular structure is compatible with organic solvents. In water, due to the large difference between its structure and the polarity of the water molecule, the solubility is not good, and it is mostly insoluble or slightly soluble.
In addition, the volatility of 1 + -ether-4 + -alkane-2 + -methylnaphthalene is moderate, and it is not extremely volatile, nor is it extremely volatile. Under appropriate temperature and air circulation conditions, it can gradually evaporate into the air. Its viscosity also has characteristics, higher than that of water, and the resistance can be felt slightly higher when flowing. This physical property needs to be taken into account in processes such as fluid transportation.
This compound is mostly liquid at room temperature, but it also depends on the specific molecular structure and surrounding environmental conditions. Looking at its color, when it is pure, it is often colorless and transparent. If it contains impurities, it may change color. Its smell has a slightly special aromatic aroma. Although it is not pungent and unpleasant, it is also unique and can be used for identification.
In terms of density, it is usually slightly lighter than water, so if mixed with water, it can float on the water surface. This property is quite useful in many practical applications and separation operations. Its boiling point is closely related to the intermolecular force. Due to the structure of the molecule, the intermolecular force is different, and the boiling point is also different. It is roughly within a certain temperature range and needs to be accurately determined by experiments.
In terms of solubility, in organic solvents such as ethanol and ether, it often shows good solubility. Due to the similar miscibility, its molecular structure is compatible with organic solvents. In water, due to the large difference between its structure and the polarity of the water molecule, the solubility is not good, and it is mostly insoluble or slightly soluble.
In addition, the volatility of 1 + -ether-4 + -alkane-2 + -methylnaphthalene is moderate, and it is not extremely volatile, nor is it extremely volatile. Under appropriate temperature and air circulation conditions, it can gradually evaporate into the air. Its viscosity also has characteristics, higher than that of water, and the resistance can be felt slightly higher when flowing. This physical property needs to be taken into account in processes such as fluid transportation.
What are the chemical properties of 1-bromo-4-chloro-2-methylbenzene
1 + -Ether-4 + -alkane-2 + -methylnaphthalene is an organic compound with unique chemical properties.
The ether structure gives it a certain solubility and stability. In many organic solvents, it can show good mutual solubility properties, just like the ancients said "water and oil are difficult to melt, and this ether can meet with many liquids". This property makes it able to play a key role in various extraction and separation processes, just like ancient craftsmen separated different materials and skillfully did it by virtue of its solubility.
The structure of 4 + -alkane gives the compound a certain saturation, making its chemical properties relatively peaceful. It is not easy to react violently with common oxidizing agents and reducing agents. It is like a calm person who is calm in the face of external disturbances. Under normal conditions, it can maintain its own structural stability and is not easy to be easily destroyed or transformed. It is like a strong fortress, which is difficult for foreign enemies to invade.
2 + -methyl naphthalene part, the naphthalene ring is a fused ring aromatic hydrocarbon structure, with certain aromaticity. This gives the compound its unique chemical activity. Under specific conditions, it can undergo electrophilic substitution reactions, like a keen hunter, capturing the reactants at the right time. The presence of methyl groups also affects the distribution of the naphthalene ring electron cloud, changing its reactivity and selectivity, just like guiding the hunter to a specific target direction.
Overall, 1 + -ether-4 + -alkane-2 + -methylnaphthalene is widely used in the field of chemistry due to its unique structure. Its solubility, stability and specific reactivity make it play an important role in organic synthesis, materials science and many other aspects, like a universal key, which can open the door to many chemical applications.
The ether structure gives it a certain solubility and stability. In many organic solvents, it can show good mutual solubility properties, just like the ancients said "water and oil are difficult to melt, and this ether can meet with many liquids". This property makes it able to play a key role in various extraction and separation processes, just like ancient craftsmen separated different materials and skillfully did it by virtue of its solubility.
The structure of 4 + -alkane gives the compound a certain saturation, making its chemical properties relatively peaceful. It is not easy to react violently with common oxidizing agents and reducing agents. It is like a calm person who is calm in the face of external disturbances. Under normal conditions, it can maintain its own structural stability and is not easy to be easily destroyed or transformed. It is like a strong fortress, which is difficult for foreign enemies to invade.
2 + -methyl naphthalene part, the naphthalene ring is a fused ring aromatic hydrocarbon structure, with certain aromaticity. This gives the compound its unique chemical activity. Under specific conditions, it can undergo electrophilic substitution reactions, like a keen hunter, capturing the reactants at the right time. The presence of methyl groups also affects the distribution of the naphthalene ring electron cloud, changing its reactivity and selectivity, just like guiding the hunter to a specific target direction.
Overall, 1 + -ether-4 + -alkane-2 + -methylnaphthalene is widely used in the field of chemistry due to its unique structure. Its solubility, stability and specific reactivity make it play an important role in organic synthesis, materials science and many other aspects, like a universal key, which can open the door to many chemical applications.
1-Bromo-4-chloro-2-methylbenzene is commonly used in which chemical reactions
1 + - + ether + - + 4 + - + alkane + - + 2 + - + methylbenzene is often used in many chemical reactions. The following is your detailed description.
In the field of organic synthesis, its uses are quite extensive. For example, in nucleophilic substitution reactions, the structural properties of the compound enable some of its atoms or groups to be replaced by nucleophiles. The existence of ether bonds allows the molecule to have a certain degree of stability and solubility, and can act as a solvent or reactant in the reaction system. When a suitable nucleophilic reagent, such as alkoxides, amines, etc., meets it, the nucleophilic reagent will attack the partially positively charged atoms in the molecule, and then realize the substitution reaction to generate new organic compounds, which is of great significance for the construction of more complex organic molecular structures.
In the reaction of aromatic compounds, the benzene ring part of methylbenzene exhibits unique chemical activity. A Fu-gram reaction can occur, whether it is a Fu-gram alkylation reaction or a Fu-gram acylation reaction. In the Fu-gram alkylation reaction, under the action of a Lewis acid catalyst, alkylation reagents such as haloalkanes can be connected to the benzene ring to introduce new alkyl groups, thereby changing the properties and structure of the molecule. The Fu-Ke acylation reaction can introduce acyl groups on the benzene ring, providing rich intermediates for organic synthesis, which can be further converted into different target products through various reactions.
In addition, in the oxidation reaction, the methyl part of methyl benzene can be oxidized. Under the action of suitable oxidants, such as potassium permanganate, methyl groups can be gradually oxidized to carboxyl groups to obtain benzoic acid compounds. This reaction is often used in organic synthesis to prepare compounds containing carboxyl groups. Carboxyl groups are important functional groups in many organic reactions, and a series of subsequent reactions such as esterification and amidation can be carried out.
1 + - + ether + - + 4 + - + alkane + - + 2 + - + methyl benzene plays a key role in many chemical reactions such as organic synthesis, aromatic reactions and oxidation reactions, and is an indispensable and important compound in the field of organic chemistry.
In the field of organic synthesis, its uses are quite extensive. For example, in nucleophilic substitution reactions, the structural properties of the compound enable some of its atoms or groups to be replaced by nucleophiles. The existence of ether bonds allows the molecule to have a certain degree of stability and solubility, and can act as a solvent or reactant in the reaction system. When a suitable nucleophilic reagent, such as alkoxides, amines, etc., meets it, the nucleophilic reagent will attack the partially positively charged atoms in the molecule, and then realize the substitution reaction to generate new organic compounds, which is of great significance for the construction of more complex organic molecular structures.
In the reaction of aromatic compounds, the benzene ring part of methylbenzene exhibits unique chemical activity. A Fu-gram reaction can occur, whether it is a Fu-gram alkylation reaction or a Fu-gram acylation reaction. In the Fu-gram alkylation reaction, under the action of a Lewis acid catalyst, alkylation reagents such as haloalkanes can be connected to the benzene ring to introduce new alkyl groups, thereby changing the properties and structure of the molecule. The Fu-Ke acylation reaction can introduce acyl groups on the benzene ring, providing rich intermediates for organic synthesis, which can be further converted into different target products through various reactions.
In addition, in the oxidation reaction, the methyl part of methyl benzene can be oxidized. Under the action of suitable oxidants, such as potassium permanganate, methyl groups can be gradually oxidized to carboxyl groups to obtain benzoic acid compounds. This reaction is often used in organic synthesis to prepare compounds containing carboxyl groups. Carboxyl groups are important functional groups in many organic reactions, and a series of subsequent reactions such as esterification and amidation can be carried out.
1 + - + ether + - + 4 + - + alkane + - + 2 + - + methyl benzene plays a key role in many chemical reactions such as organic synthesis, aromatic reactions and oxidation reactions, and is an indispensable and important compound in the field of organic chemistry.
What is the synthesis method of 1-bromo-4-chloro-2-methylbenzene?
To prepare 1-bromo-4-iodine-2-methylbenzene, the following method can be followed.
First take toluene as the starting material, use the mixed acid of concentrated sulfuric acid and concentrated nitric acid as the reagent, and carry out the nitration reaction at an appropriate temperature. The methyl group of toluene is an ortho-para-localization group, so the nitro group is mainly introduced into the para-position of the methyl group to obtain p-nitrotoluene. The principle of this reaction is that the nitro positive ion attacks the benzene ring as an electrophilic reagent, and the methyl group increases the density of the ortho-para-electron cloud of the benzene ring, which is more prone to electrophilic substitution.
After obtaining p-nitrotoluene, iron powder and hydrochloric acid are used as reducing agents to reduce the nitro group to an amino group This reduction process is based on the generation of new hydrogen between iron powder and hydrochloric acid, and then the nitro group is gradually reduced to an amino group.
Next, p-aminotoluene is treated with sodium nitrite and hydrochloric acid at low temperature, and a diazotization reaction occurs to form a diazonium salt. This diazosalt is active and needs to be stored and reacted at low temperature to prevent its decomposition. After
, a potassium iodide solution is added, and the diazoyl group is replaced by an iodine atom to obtain p-iotoluene. This is a variant of the Sandmeier reaction, which uses the properties of diazonium salts to achieve the introduction of iodine atoms.
Then bromine and iron powder are used as reagents, and p-iotoluene and bromine are brominated under the catalysis Because methyl is an ortho-ortho-localization group, and the iodine atom has a weak activation effect on the benzene ring, bromine atoms are mainly introduced into the ortho-site of methyl to obtain the target product 1-bromo-4-iodine-2-methylbenzene. In this bromination reaction, iron powder first reacts with bromine to form iron bromide, which catalyzes bromine to produce positive bromide ions, and then attacks the benzene ring to undergo electrophilic substitution.
After these several steps, 1-bromo-4-iodine-2-methylbenzene can be obtained. The reaction conditions must be strictly controlled at each step to ensure the smooth progress of the reaction and the purity and yield of the product.
First take toluene as the starting material, use the mixed acid of concentrated sulfuric acid and concentrated nitric acid as the reagent, and carry out the nitration reaction at an appropriate temperature. The methyl group of toluene is an ortho-para-localization group, so the nitro group is mainly introduced into the para-position of the methyl group to obtain p-nitrotoluene. The principle of this reaction is that the nitro positive ion attacks the benzene ring as an electrophilic reagent, and the methyl group increases the density of the ortho-para-electron cloud of the benzene ring, which is more prone to electrophilic substitution.
After obtaining p-nitrotoluene, iron powder and hydrochloric acid are used as reducing agents to reduce the nitro group to an amino group This reduction process is based on the generation of new hydrogen between iron powder and hydrochloric acid, and then the nitro group is gradually reduced to an amino group.
Next, p-aminotoluene is treated with sodium nitrite and hydrochloric acid at low temperature, and a diazotization reaction occurs to form a diazonium salt. This diazosalt is active and needs to be stored and reacted at low temperature to prevent its decomposition. After
, a potassium iodide solution is added, and the diazoyl group is replaced by an iodine atom to obtain p-iotoluene. This is a variant of the Sandmeier reaction, which uses the properties of diazonium salts to achieve the introduction of iodine atoms.
Then bromine and iron powder are used as reagents, and p-iotoluene and bromine are brominated under the catalysis Because methyl is an ortho-ortho-localization group, and the iodine atom has a weak activation effect on the benzene ring, bromine atoms are mainly introduced into the ortho-site of methyl to obtain the target product 1-bromo-4-iodine-2-methylbenzene. In this bromination reaction, iron powder first reacts with bromine to form iron bromide, which catalyzes bromine to produce positive bromide ions, and then attacks the benzene ring to undergo electrophilic substitution.
After these several steps, 1-bromo-4-iodine-2-methylbenzene can be obtained. The reaction conditions must be strictly controlled at each step to ensure the smooth progress of the reaction and the purity and yield of the product.
What are the application fields of 1 - bromo - 4 - chloro - 2 - methylbenzene
1+-+%E6%BA%B4+-+4+-+%E6%B0%AF+-+2+-+%E7%94%B2%E5%9F%BA%E8%8B%AF, this medicine is also known as fairy grass, which is toxic to the kidney, liver and spleen meridians. Fairy grass is used in many fields:
- ** Supplement kidney yang **: Fairy grass is often used for kidney yang deficiency. Kidney yang is the root of human yang. If the kidney yang is insufficient, men can see impotence and premature ejaculation, waist and knee soreness, cold limbs, etc.; women have palace cold infertility, irregular menstruation, etc. Fairy grass can warm the kidney yang, stimulate the kidney's yang, and improve such symptoms. For example, Fairy grass pills in "Shengji General Records" are used to treat kidney yang deficiency, muscle and bone weakness.
- ** Strength the muscles and bones **: It can strengthen the tendons and bones, and has a good effect on the muscles and bones that are weak and soft, and the cold pain of the waist and knee caused by the lack of liver and kidney. Liver and kidney are closely related to the muscles and bones. The liver and kidney are the main tendons, and the kidney are the main bones. If the liver and kidney are deficient, the muscles and bones are not nourished. Curculiae can nourish the liver and kidney and enhance the function of the muscles and bones. As recorded in the Compendium of Materia Medica, Curculiae soaked in wine alone can treat the cold and convulsive paralysis of the waist and knee.
- ** Remove cold and dampness **: Curculiae has the ability to remove cold and dampness, which is suitable for cold and Fairy grass is hot, can dispel cold and dampness, clear collaterals and relieve pain. Such as the Sanbi Decoction in "Taiping Huimin and Pharmaceutical Bureau Prescription", can treat wind, cold and dampness.
- ** Warming the spleen and relieving diarrhea **: Fairy grass also has an effect on diarrhea caused by spleen and kidney yang deficiency. The spleen is the main transport and transformation, and the kidney is the gate of the stomach. The spleen and kidney yang are weak, and the transportation and transformation of the spleen and kidney are lost, which can cause diarrhea. Fairy grass can warm the spleen and yang, replenish the kidney yang, restore the function of spleen and kidney transportation and transformation, and stop diarrhea and diarrhea.
However, Fairy grass is toxic. It should be used with caution. The doctor's advice should be strictly
- ** Supplement kidney yang **: Fairy grass is often used for kidney yang deficiency. Kidney yang is the root of human yang. If the kidney yang is insufficient, men can see impotence and premature ejaculation, waist and knee soreness, cold limbs, etc.; women have palace cold infertility, irregular menstruation, etc. Fairy grass can warm the kidney yang, stimulate the kidney's yang, and improve such symptoms. For example, Fairy grass pills in "Shengji General Records" are used to treat kidney yang deficiency, muscle and bone weakness.
- ** Strength the muscles and bones **: It can strengthen the tendons and bones, and has a good effect on the muscles and bones that are weak and soft, and the cold pain of the waist and knee caused by the lack of liver and kidney. Liver and kidney are closely related to the muscles and bones. The liver and kidney are the main tendons, and the kidney are the main bones. If the liver and kidney are deficient, the muscles and bones are not nourished. Curculiae can nourish the liver and kidney and enhance the function of the muscles and bones. As recorded in the Compendium of Materia Medica, Curculiae soaked in wine alone can treat the cold and convulsive paralysis of the waist and knee.
- ** Remove cold and dampness **: Curculiae has the ability to remove cold and dampness, which is suitable for cold and Fairy grass is hot, can dispel cold and dampness, clear collaterals and relieve pain. Such as the Sanbi Decoction in "Taiping Huimin and Pharmaceutical Bureau Prescription", can treat wind, cold and dampness.
- ** Warming the spleen and relieving diarrhea **: Fairy grass also has an effect on diarrhea caused by spleen and kidney yang deficiency. The spleen is the main transport and transformation, and the kidney is the gate of the stomach. The spleen and kidney yang are weak, and the transportation and transformation of the spleen and kidney are lost, which can cause diarrhea. Fairy grass can warm the spleen and yang, replenish the kidney yang, restore the function of spleen and kidney transportation and transformation, and stop diarrhea and diarrhea.
However, Fairy grass is toxic. It should be used with caution. The doctor's advice should be strictly
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